{"id":"https://openalex.org/W2005256772","doi":"https://doi.org/10.1002/bimj.200800159","title":"Comparing Accuracy in an Unpaired Post\u2010market Device Study with Incomplete Disease Assessment","display_name":"Comparing Accuracy in an Unpaired Post\u2010market Device Study with Incomplete Disease Assessment","publication_year":2009,"publication_date":"2009-07-01","ids":{"openalex":"https://openalex.org/W2005256772","doi":"https://doi.org/10.1002/bimj.200800159","mag":"2005256772","pmid":"https://pubmed.ncbi.nlm.nih.gov/19572317"},"language":"en","primary_location":{"id":"doi:10.1002/bimj.200800159","doi":"https://doi.org/10.1002/bimj.200800159","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bimj.200800159","pdf_url":null,"source":{"id":"https://openalex.org/S126457381","display_name":"Biometrical Journal","issn_l":"0323-3847","issn":["0323-3847","1521-4036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-b","anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biometrical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066861312","display_name":"Todd A. Alonzo","orcid":"https://orcid.org/0000-0002-6772-6581","observed_orcids":["https://orcid.org/0000-0002-6772-6581"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Todd A. Alonzo","raw_affiliation_strings":["Division of Biostatistics, University of Southern California Keck School of Medicine, 440 E. Huntington Dr, 4th floor, Arcadia, CA 91006, USA. talonzo@childrensoncologygroup.org","Division of Biostatistics, University of Southern California Keck School of Medicine, 440 E Huntington Dr., 4th Floor, Arcadia, CA 91006, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biostatistics, University of Southern California Keck School of Medicine, 440 E. Huntington Dr, 4th floor, Arcadia, CA 91006, USA. talonzo@childrensoncologygroup.org","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Division of Biostatistics, University of Southern California Keck School of Medicine, 440 E Huntington Dr., 4th Floor, Arcadia, CA 91006, USA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5066861312"],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.2733,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62579067,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"51","issue":"3","first_page":"491","last_page":"503"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14374","display_name":"Statistical Methods in Epidemiology","score":0.18129999935626984,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-standard","display_name":"gold standard","score":0.5410000085830688},{"id":"https://openalex.org/keywords/confidence-intervals","display_name":"confidence intervals","score":0.7570000290870667},{"id":"https://openalex.org/keywords/small-sample-bias","display_name":"small sample bias","score":0.753000020980835},{"id":"https://openalex.org/keywords/variance-estimation","display_name":"variance estimation","score":0.7860000133514404},{"id":"https://openalex.org/keywords/cervical-cancer-screening","display_name":"cervical cancer screening","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.494431734085083},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3958035707473755},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3664920926094055},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.361357718706131},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3387730121612549},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.32700201869010925}],"mesh":[{"descriptor_ui":"D001699","descriptor_name":"Biometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001699","descriptor_name":"Biometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001699","descriptor_name":"Biometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011358","descriptor_name":"Product Surveillance, Postmarketing","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011933","descriptor_name":"Reagent Kits, Diagnostic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011933","descriptor_name":"Reagent Kits, Diagnostic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011933","descriptor_name":"Reagent Kits, Diagnostic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018401","descriptor_name":"Sample Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019544","descriptor_name":"Equipment Failure Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/bimj.200800159","doi":"https://doi.org/10.1002/bimj.200800159","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bimj.200800159","pdf_url":null,"source":{"id":"https://openalex.org/S126457381","display_name":"Biometrical Journal","issn_l":"0323-3847","issn":["0323-3847","1521-4036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["abdc-b","anvur-class-a","anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biometrical Journal","raw_type":"journal-article"},{"id":"pmid:19572317","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19572317","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biometrical journal. Biometrische Zeitschrift","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5899999737739563}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1982890131","https://openalex.org/W1985309655","https://openalex.org/W2017807729","https://openalex.org/W2027337728","https://openalex.org/W2076857458","https://openalex.org/W2110076575","https://openalex.org/W2134063700","https://openalex.org/W2165244071","https://openalex.org/W2326945647","https://openalex.org/W2339926369","https://openalex.org/W4233471163","https://openalex.org/W4388317518"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725","https://openalex.org/W2148612803"],"abstract_inverted_index":{"The":[0,134],"sensitivity":[1],"and":[2,24,78,95,123,130],"specificity":[3],"of":[4,15,22,75,90,93,120,126,143,152],"a":[5,144,153],"new":[6,154],"medical":[7],"device":[8,18,79,155],"are":[9,84,99,112,138],"often":[10,51],"compared":[11],"relative":[12],"to":[13,35,56,85,114,140,148],"that":[14],"an":[16],"existing":[17],"by":[19],"calculating":[20],"ratios":[21],"sensitivities":[23],"specificities.":[25],"Although":[26],"it":[27,49],"would":[28],"be":[29],"ideal":[30],"for":[31,46,60,101],"all":[32,47],"study":[33,147],"subjects":[34,83],"receive":[36,86],"the":[37,76,91,116,121,124,127,141,150,157],"gold":[38],"standard":[39],"so":[40],"true":[41],"disease":[42,58,87],"status":[43,59],"was":[44],"known":[45],"subjects,":[48],"is":[50,71],"not":[52],"feasible":[53],"or":[54],"ethical":[55],"obtain":[57],"everyone.":[61],"This":[62],"paper":[63],"proposes":[64],"two":[65],"unpaired":[66],"designs":[67,103],"where":[68],"each":[69],"subject":[70],"only":[72],"administered":[73],"one":[74],"devices":[77],"results":[80],"dictate":[81],"which":[82],"verification.":[88],"Estimators":[89],"ratio":[92],"accuracy":[94,151],"corresponding":[96],"confidence":[97],"intervals":[98],"proposed":[100],"these":[102],"as":[104,106],"well":[105],"sample":[107,118,131,135],"size":[108,132,136],"formulae.":[109,133],"Simulation":[110],"studies":[111],"performed":[113],"investigate":[115],"small":[117],"bias":[119],"estimators":[122,129],"performance":[125],"variance":[128],"formulae":[137],"applied":[139],"design":[142],"cervical":[145],"cancer":[146],"compare":[149],"with":[156],"conventional":[158],"Pap":[159],"smear.":[160]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-10T00:00:00"}