{"id":"https://openalex.org/W2005245887","doi":"https://doi.org/10.1016/s1059-1311(95)80098-0","title":"Deliberate overdose with the novel anticonvulsant tiagabine","display_name":"Deliberate overdose with the novel anticonvulsant tiagabine","publication_year":1995,"publication_date":"1995-06-01","ids":{"openalex":"https://openalex.org/W2005245887","doi":"https://doi.org/10.1016/s1059-1311(95)80098-0","mag":"2005245887","pmid":"https://pubmed.ncbi.nlm.nih.gov/7670769"},"language":"en","primary_location":{"id":"doi:10.1016/s1059-1311(95)80098-0","doi":"https://doi.org/10.1016/s1059-1311(95)80098-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","pdf_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","source":{"id":"https://openalex.org/S45493217","display_name":"Seizure","issn_l":"1059-1311","issn":["1059-1311","1532-2688"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seizure","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056844581","display_name":"John Paul Leach","orcid":"https://orcid.org/0000-0003-2086-9937","observed_orcids":["https://orcid.org/0000-0003-2086-9937"]},"institutions":[{"id":"https://openalex.org/I2801120601","display_name":"Western Infirmary","ror":"https://ror.org/02e22bh87","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800201399","https://openalex.org/I2801120601"]},{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J.P. Leach","raw_affiliation_strings":["University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland, UK","Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Department of Medicine and Therapeutics, Western Infirmary, Glasgow, Scotland, UK","institution_ids":["https://openalex.org/I2801120601","https://openalex.org/I7882870"]},{"raw_affiliation_string":"Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK","institution_ids":["https://openalex.org/I2801120601"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028419147","display_name":"Iwona Stolarek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801120601","display_name":"Western Infirmary","ror":"https://ror.org/02e22bh87","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800201399","https://openalex.org/I2801120601"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I. Stolarek","raw_affiliation_strings":["Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK","institution_ids":["https://openalex.org/I2801120601"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025489238","display_name":"Martin J. Brodie","orcid":"https://orcid.org/0000-0003-1781-2892","observed_orcids":["https://orcid.org/0000-0003-1781-2892"]},"institutions":[{"id":"https://openalex.org/I2801120601","display_name":"Western Infirmary","ror":"https://ror.org/02e22bh87","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800201399","https://openalex.org/I2801120601"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"M.J. Brodie","raw_affiliation_strings":["Epilepsy Research Unit, Department of Medicine and Therapeutics, Western Infirmary, Glasgow Gll 6NT, Scotland, UK","Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsy Research Unit, Department of Medicine and Therapeutics, Western Infirmary, Glasgow Gll 6NT, Scotland, UK","institution_ids":["https://openalex.org/I2801120601"]},{"raw_affiliation_string":"Epilepsy Research Unit, University Department of Medicine and Therapeutics, Western Infirmary, Glasgow G11 6NT, Scotland, UK","institution_ids":["https://openalex.org/I2801120601"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2970,"currency":"USD","value_usd":2970},"apc_paid":null,"fwci":3.8418,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.92780488,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"2","first_page":"155","last_page":"157"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.986299991607666,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tiagabine","display_name":"tiagabine","score":0.9359999895095825},{"id":"https://openalex.org/keywords/anticonvulsant-poisoning","display_name":"anticonvulsant poisoning","score":0.7799999713897705},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.8410000205039978},{"id":"https://openalex.org/keywords/phenytoin","display_name":"phenytoin","score":0.9480000138282776},{"id":"https://openalex.org/keywords/gaba-uptake-inhibition","display_name":"GABA uptake inhibition","score":0.6980000138282776},{"id":"https://openalex.org/keywords/coma","display_name":"coma","score":0.9490000009536743},{"id":"https://openalex.org/keywords/plasma-drug-concentration","display_name":"plasma drug concentration","score":0.9079999923706055},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.42500001192092896}],"concepts":[{"id":"https://openalex.org/C2776749334","wikidata":"https://www.wikidata.org/wiki/Q907219","display_name":"Tiagabine","level":4,"score":0.9654325842857361},{"id":"https://openalex.org/C2778337148","wikidata":"https://www.wikidata.org/wiki/Q410400","display_name":"Phenytoin","level":3,"score":0.7219681739807129},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6581885814666748},{"id":"https://openalex.org/C2775858608","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Anticonvulsant","level":3,"score":0.6367983222007751},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5731180906295776},{"id":"https://openalex.org/C2776315796","wikidata":"https://www.wikidata.org/wiki/Q3505252","display_name":"Drug overdose","level":3,"score":0.5286564826965332},{"id":"https://openalex.org/C100136789","wikidata":"https://www.wikidata.org/wiki/Q1772448","display_name":"Coma (optics)","level":2,"score":0.5246812701225281},{"id":"https://openalex.org/C2777288759","wikidata":"https://www.wikidata.org/wiki/Q4164182","display_name":"Dosing","level":2,"score":0.486095666885376},{"id":"https://openalex.org/C2994127763","wikidata":"https://www.wikidata.org/wiki/Q576618","display_name":"Antiepileptic drug","level":3,"score":0.48202550411224365},{"id":"https://openalex.org/C2777172819","wikidata":"https://www.wikidata.org/wiki/Q240642","display_name":"Valproic Acid","level":3,"score":0.48043227195739746},{"id":"https://openalex.org/C2779253243","wikidata":"https://www.wikidata.org/wiki/Q410412","display_name":"Carbamazepine","level":3,"score":0.4596824645996094},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.44460269808769226},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.4418075382709503},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.3595413565635681},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.2771165668964386},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.16136899590492249},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14475983381271362},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000078308","descriptor_name":"Tiagabine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000927","descriptor_name":"Anticonvulsants","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":true},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008657","descriptor_name":"Metabolic Clearance Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009557","descriptor_name":"Nipecotic Acids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D009557","descriptor_name":"Nipecotic Acids","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D009557","descriptor_name":"Nipecotic Acids","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":true},{"descriptor_ui":"D010672","descriptor_name":"Phenytoin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010672","descriptor_name":"Phenytoin","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D017029","descriptor_name":"Epilepsy, Complex Partial","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D017029","descriptor_name":"Epilepsy, Complex Partial","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1059-1311(95)80098-0","doi":"https://doi.org/10.1016/s1059-1311(95)80098-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","pdf_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","source":{"id":"https://openalex.org/S45493217","display_name":"Seizure","issn_l":"1059-1311","issn":["1059-1311","1532-2688"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seizure","raw_type":"journal-article"},{"id":"pmid:7670769","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7670769","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seizure","raw_type":"Case Reports"}],"best_oa_location":{"id":"doi:10.1016/s1059-1311(95)80098-0","doi":"https://doi.org/10.1016/s1059-1311(95)80098-0","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","pdf_url":"https://doi.org/10.1016/s1059-1311(95)80098-0","source":{"id":"https://openalex.org/S45493217","display_name":"Seizure","issn_l":"1059-1311","issn":["1059-1311","1532-2688"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seizure","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005245887.pdf","grobid_xml":"https://content.openalex.org/works/W2005245887.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1974018738","https://openalex.org/W1975242088","https://openalex.org/W1991325525","https://openalex.org/W1993363672","https://openalex.org/W1999183705","https://openalex.org/W1999563355","https://openalex.org/W2000282731","https://openalex.org/W2008994051","https://openalex.org/W2017477656","https://openalex.org/W2041907686","https://openalex.org/W2048138234","https://openalex.org/W2108104758","https://openalex.org/W2121413985","https://openalex.org/W2133283083","https://openalex.org/W2398941113","https://openalex.org/W2418352060","https://openalex.org/W2432135359","https://openalex.org/W4244558413","https://openalex.org/W4253708312"],"related_works":["https://openalex.org/W2115916359","https://openalex.org/W7095565463","https://openalex.org/W2033964706","https://openalex.org/W2082773281","https://openalex.org/W2234990544","https://openalex.org/W2000278577","https://openalex.org/W1981123624","https://openalex.org/W2013672722","https://openalex.org/W2476117120","https://openalex.org/W2067249871"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}