{"id":"https://openalex.org/W2005237857","doi":"https://doi.org/10.1097/00128360-200607000-00010","title":"A Phase 2, Randomized, Multicenter Study of 1 or 3 Doses of ZYC101A in the Treatment of High-grade Squamous Intraepithelial Lesions of the Uterine Cervix","display_name":"A Phase 2, Randomized, Multicenter Study of 1 or 3 Doses of ZYC101A in the Treatment of High-grade Squamous Intraepithelial Lesions of the Uterine Cervix","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2005237857","doi":"https://doi.org/10.1097/00128360-200607000-00010","mag":"2005237857"},"language":"en","primary_location":{"id":"doi:10.1097/00128360-200607000-00010","doi":"https://doi.org/10.1097/00128360-200607000-00010","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00128360-200607000-00010","pdf_url":null,"source":{"id":"https://openalex.org/S6499114","display_name":"Journal of Lower Genital Tract Disease","issn_l":"1089-2591","issn":["1089-2591","1526-0976"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lower Genital Tract Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111526604","display_name":"Laila I. Muderspach","orcid":"https://orcid.org/0009-0006-4439-7216","observed_orcids":["https://orcid.org/0009-0006-4439-7216"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Muderspach","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110562007","display_name":"L. Roman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Roman","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091834693","display_name":"Alexander Burnett","orcid":"https://orcid.org/0000-0002-1682-785X","observed_orcids":["https://orcid.org/0000-0002-1682-785X"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Burnett","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108495127","display_name":"P. Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Lin","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113669934","display_name":"A. O\u2019Meara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. O'Meara","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022221184","display_name":"Dominic P. Bua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Bua","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091540540","display_name":"Sharon Poltis Wilczynski","orcid":"https://orcid.org/0009-0004-3063-786X","observed_orcids":["https://orcid.org/0009-0004-3063-786X"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Wilczynski","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047177507","display_name":"Jeffrey S. Weber","orcid":"https://orcid.org/0000-0002-4962-2957","observed_orcids":["https://orcid.org/0000-0002-4962-2957"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Weber","raw_affiliation_strings":["Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","The University of Southern California, Los Angeles, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug supplies used to conduct this study were provided by MGI PHARMA Biologics, Lexington, Mass","institution_ids":[]},{"raw_affiliation_string":"The University of Southern California, Los Angeles, CA","institution_ids":["https://openalex.org/I1174212"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1174212"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"3","first_page":"170","last_page":"170"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-grade-squamous-intraepithelial-lesion","display_name":"high-grade squamous intraepithelial lesion","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cervix","display_name":"uterine cervix","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"cervical intraepithelial neoplasia","score":0.800000011920929},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.3970000147819519},{"id":"https://openalex.org/keywords/oncolytic-adenovirus","display_name":"oncolytic adenovirus","score":0.5630000233650208},{"id":"https://openalex.org/keywords/dose-comparison","display_name":"dose comparison","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9216336011886597},{"id":"https://openalex.org/C2992879611","wikidata":"https://www.wikidata.org/wiki/Q666412","display_name":"Uterine cervix","level":3,"score":0.6417385935783386},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.6077938675880432},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4986710548400879},{"id":"https://openalex.org/C2777740455","wikidata":"https://www.wikidata.org/wiki/Q666412","display_name":"Cervix","level":3,"score":0.49259454011917114},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.41827893257141113},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2984965741634369},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.04800030589103699},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00128360-200607000-00010","doi":"https://doi.org/10.1097/00128360-200607000-00010","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00128360-200607000-00010","pdf_url":null,"source":{"id":"https://openalex.org/S6499114","display_name":"Journal of Lower Genital Tract Disease","issn_l":"1089-2591","issn":["1089-2591","1526-0976"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lower Genital Tract Disease","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1973871686","https://openalex.org/W2081481464","https://openalex.org/W4245361766","https://openalex.org/W7043978175","https://openalex.org/W2321014394","https://openalex.org/W2967758309","https://openalex.org/W3034280807","https://openalex.org/W7036659720","https://openalex.org/W2424254617","https://openalex.org/W2064401768"],"abstract_inverted_index":{"Muderspach,":[0],"L.":[1,4],"MD;":[2,5,8,11,14,17,20],"Roman,":[3],"Burnett,":[6],"A.":[7,13],"Lin,":[9],"P.":[10],"O'Meara,":[12],"Bua,":[15],"D.":[16],"Wilczynski,":[18],"S.":[19],"Weber,":[21],"J.":[22],"MD,":[23],"PhD":[24],"Author":[25],"Information":[26]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}