{"id":"https://openalex.org/W2005229673","doi":"https://doi.org/10.1101/sqb.1983.048.01.059","title":"Do Monoclonal Antibodies Stain Sets of Functionally Related Leech Neurons?","display_name":"Do Monoclonal Antibodies Stain Sets of Functionally Related Leech Neurons?","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W2005229673","doi":"https://doi.org/10.1101/sqb.1983.048.01.059","mag":"2005229673","pmid":"https://pubmed.ncbi.nlm.nih.gov/6373109"},"language":"en","primary_location":{"id":"doi:10.1101/sqb.1983.048.01.059","doi":"https://doi.org/10.1101/sqb.1983.048.01.059","is_oa":false,"landing_page_url":"https://doi.org/10.1101/sqb.1983.048.01.059","pdf_url":null,"source":{"id":"https://openalex.org/S78756772","display_name":"Cold Spring Harbor Symposia on Quantitative Biology","issn_l":"0091-7451","issn":["0091-7451","1943-4456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Symposia on Quantitative Biology","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041733259","display_name":"Birgit Zipser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Zipser","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027","institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108610863","display_name":"Randall R. Stewart","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Stewart","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027","institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Flanagan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Flanagan","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027","institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111761967","display_name":"Murray S. Flaster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Flaster","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027","institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111491820","display_name":"ER Macagno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.R. Macagno","raw_affiliation_strings":["Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724; Department of Biological Sciences, Columbia University, New York, New York 10027","institution_ids":["https://openalex.org/I2750212522","https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"48","issue":"0","first_page":"551","last_page":"556"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.8398000001907349,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13767","display_name":"Leech Biology and Applications","score":0.048900000751018524,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.04340000078082085,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leeches","display_name":"leeches","score":0.7260000109672546},{"id":"https://openalex.org/keywords/neuron-identification","display_name":"neuronal identification","score":0.43299999833106995},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8429999947547913},{"id":"https://openalex.org/keywords/serotonergic-neurons","display_name":"serotonergic neurons","score":0.7760000228881836},{"id":"https://openalex.org/keywords/cholinergic-neurons","display_name":"cholinergic neurons","score":0.9990000128746033},{"id":"https://openalex.org/keywords/segmental-ganglia","display_name":"segmental ganglia","score":0.7699999809265137},{"id":"https://openalex.org/keywords/molecular-markers","display_name":"molecular markers","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C180746962","wikidata":"https://www.wikidata.org/wiki/Q243147","display_name":"Leech","level":2,"score":0.9653294682502747},{"id":"https://openalex.org/C2781334511","wikidata":"https://www.wikidata.org/wiki/Q108158","display_name":"Ganglion","level":2,"score":0.8009384870529175},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.6704736351966858},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5622934103012085},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4866688847541809},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.46678483486175537},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.288138747215271},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1993863880634308},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08981850743293762},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005724","descriptor_name":"Ganglia","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D005724","descriptor_name":"Ganglia","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007865","descriptor_name":"Leeches","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1101/sqb.1983.048.01.059","doi":"https://doi.org/10.1101/sqb.1983.048.01.059","is_oa":false,"landing_page_url":"https://doi.org/10.1101/sqb.1983.048.01.059","pdf_url":null,"source":{"id":"https://openalex.org/S78756772","display_name":"Cold Spring Harbor Symposia on Quantitative Biology","issn_l":"0091-7451","issn":["0091-7451","1943-4456"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor Symposia on Quantitative Biology","raw_type":"journal-article"},{"id":"pmid:6373109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6373109","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cold Spring Harbor symposia on quantitative biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053437366","https://openalex.org/W1965109462","https://openalex.org/W2060947097","https://openalex.org/W1484033711","https://openalex.org/W1961435717","https://openalex.org/W934671993","https://openalex.org/W2003557119","https://openalex.org/W2042819511","https://openalex.org/W1552456854","https://openalex.org/W2027568528"],"abstract_inverted_index":{"Are":[0],"sets":[1],"of":[2,33,48,62,75,90,99],"functionally":[3],"related":[4],"neurons":[5,27,34,47,61,76,101],"made":[6],"recognizable":[7],"by":[8],"a":[9,36,87,97],"common":[10,37],"molecular":[11,38],"marker?":[12],"This":[13],"question":[14],"is":[15],"favorably":[16],"studied":[17],"in":[18,40,92,102],"an":[19],"organism":[20],"such":[21],"as":[22],"the":[23,41,44,49,58,63,73,80],"leech,":[24],"where":[25],"all":[26],"are":[28],"individually":[29],"identifiable.":[30],"Three":[31],"examples":[32],"sharing":[35],"marker":[39],"leech":[42],"included":[43],"seven":[45],"serotonergic":[46],"standard":[50,64],"midbody":[51,65],"segmental":[52,66,94],"ganglion":[53,67,95],"(Stuart":[54],"et":[55],"al.":[56],"1974),":[57],"44":[59],"cholinergic":[60],"(Wallace":[68],"and":[69,72,96,105,108],"Gillon":[70],"1981),":[71],"set":[74],"that":[77],"stains":[78,86],"with":[79],"monoclonal":[81],"antibody":[82],"(mAb)":[83],"Lan3-1.":[84],"Lan3-1":[85],"single":[88],"pair":[89,98],"cells":[91],"each":[93],"sex":[100],"ganglia":[103],"5":[104],"6":[106],"(Zipser":[107],"McKay":[109],"1981;":[110],"Zipser":[111],"1982).":[112]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}