{"id":"https://openalex.org/W2005201877","doi":"https://doi.org/10.1016/0039-128x(90)90098-v","title":"Peptidyl aminosteroids as potential new antiarrhythmic agents","display_name":"Peptidyl aminosteroids as potential new antiarrhythmic agents","publication_year":1990,"publication_date":"1990-09-01","ids":{"openalex":"https://openalex.org/W2005201877","doi":"https://doi.org/10.1016/0039-128x(90)90098-v","mag":"2005201877","pmid":"https://pubmed.ncbi.nlm.nih.gov/2281517"},"language":"en","primary_location":{"id":"doi:10.1016/0039-128x(90)90098-v","doi":"https://doi.org/10.1016/0039-128x(90)90098-v","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0039-128x(90)90098-v","pdf_url":null,"source":{"id":"https://openalex.org/S70286497","display_name":"Steroids","issn_l":"0039-128X","issn":["0039-128X","1878-5867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015945268","display_name":"Michael Mokotoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Mokotoff","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261","Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh , Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh , Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014915114","display_name":"Ming Zhao","orcid":"https://orcid.org/0000-0001-5184-4826","observed_orcids":["https://orcid.org/0000-0001-5184-4826"]},"institutions":[{"id":"https://openalex.org/I161716053","display_name":"China Pharmaceutical University","ror":"https://ror.org/01sfm2718","country_code":"CN","type":"education","lineage":["https://openalex.org/I161716053"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Ming Zhao","raw_affiliation_strings":["China Pharmaceutical University, Nanjing, People's Republic of China","Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China Pharmaceutical University, Nanjing, People's Republic of China","institution_ids":["https://openalex.org/I161716053"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035160663","display_name":"Richard Marshall","orcid":"https://orcid.org/0000-0001-8278-167X","observed_orcids":["https://orcid.org/0000-0001-8278-167X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard J. Marshall","raw_affiliation_strings":["Organon Laboratories, Ltd., Newhouse, Lanarkshire, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organon Laboratories, Ltd., Newhouse, Lanarkshire, Scotland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110078084","display_name":"EILEEN WINSLOW","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eileen Winslow","raw_affiliation_strings":["Organon Laboratories, Ltd., Newhouse, Lanarkshire, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organon Laboratories, Ltd., Newhouse, Lanarkshire, Scotland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110361011","display_name":"Lan K. Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lan K. Wong","raw_affiliation_strings":["Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073426289","display_name":"Liao Qing-jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161716053","display_name":"China Pharmaceutical University","ror":"https://ror.org/01sfm2718","country_code":"CN","type":"education","lineage":["https://openalex.org/I161716053"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing-Jiang Liao","raw_affiliation_strings":["China Pharmaceutical University, Nanjing, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China Pharmaceutical University, Nanjing, People's Republic of China","institution_ids":["https://openalex.org/I161716053"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5015945268"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":0.4409,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.55459664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"55","issue":"9","first_page":"399","last_page":"404"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.739300012588501,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.739300012588501,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.20759999752044678,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.011599999852478504,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiarrhythmic-drugs","display_name":"antiarrhythmic drugs","score":0.9900000095367432},{"id":"https://openalex.org/keywords/peptide-synthesis","display_name":"peptide synthesis","score":0.6980000138282776},{"id":"https://openalex.org/keywords/hydrochloride","display_name":"hydrochloride salts","score":0.5910000205039978},{"id":"https://openalex.org/keywords/proline-containing-peptides","display_name":"proline-containing peptides","score":0.5789999961853027},{"id":"https://openalex.org/keywords/oral-bioavailability","display_name":"oral bioavailability","score":0.5820000171661377},{"id":"https://openalex.org/keywords/intravenous-administration","display_name":"intravenous administration","score":0.6660000085830688}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7109935283660889},{"id":"https://openalex.org/C2776460385","wikidata":"https://www.wikidata.org/wiki/Q420060","display_name":"Hydrochloride","level":2,"score":0.6458188891410828},{"id":"https://openalex.org/C40875361","wikidata":"https://www.wikidata.org/wiki/Q2356542","display_name":"Reagent","level":2,"score":0.5864270925521851},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4433768093585968},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4003427028656006},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.3763883113861084},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15521034598350525},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12988024950027466},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11124145984649658}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000732","descriptor_name":"Androstanols","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D000732","descriptor_name":"Androstanols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000889","descriptor_name":"Anti-Arrhythmia Agents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D007275","descriptor_name":"Injections, Intravenous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011355","descriptor_name":"Prodrugs","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0039-128x(90)90098-v","doi":"https://doi.org/10.1016/0039-128x(90)90098-v","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0039-128x(90)90098-v","pdf_url":null,"source":{"id":"https://openalex.org/S70286497","display_name":"Steroids","issn_l":"0039-128X","issn":["0039-128X","1878-5867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"journal-article"},{"id":"pmid:2281517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2281517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W129728540","https://openalex.org/W1963962146","https://openalex.org/W1975320825","https://openalex.org/W2021185924","https://openalex.org/W2023970272","https://openalex.org/W2042229465","https://openalex.org/W2053681205","https://openalex.org/W2056426468","https://openalex.org/W2066455616","https://openalex.org/W2094426747","https://openalex.org/W2163947903"],"related_works":["https://openalex.org/W2951911965","https://openalex.org/W2951614292","https://openalex.org/W2051707022","https://openalex.org/W67534787","https://openalex.org/W2055725040","https://openalex.org/W2048654882","https://openalex.org/W2952100778","https://openalex.org/W2949326243","https://openalex.org/W1991729437","https://openalex.org/W2364839478"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}