{"id":"https://openalex.org/W2005197797","doi":"https://doi.org/10.1063/1.3657855","title":"Interpreting single turnover catalysis measurements with constrained mean dwell times","display_name":"Interpreting single turnover catalysis measurements with constrained mean dwell times","publication_year":2011,"publication_date":"2011-11-07","ids":{"openalex":"https://openalex.org/W2005197797","doi":"https://doi.org/10.1063/1.3657855","mag":"2005197797","pmid":"https://pubmed.ncbi.nlm.nih.gov/22070308"},"language":"en","primary_location":{"id":"doi:10.1063/1.3657855","doi":"https://doi.org/10.1063/1.3657855","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.3657855","pdf_url":null,"source":{"id":"https://openalex.org/S77047749","display_name":"The Journal of Chemical Physics","issn_l":"0021-9606","issn":["0021-9606","1089-7690","1520-9032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Chemical Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062409757","display_name":"Maicol A. Ochoa","orcid":"https://orcid.org/0000-0003-2056-7736","observed_orcids":["https://orcid.org/0000-0003-2056-7736"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maicol A. Ochoa","raw_affiliation_strings":["Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077684535","display_name":"Xiaochun Zhou","orcid":"https://orcid.org/0000-0001-9793-6072","observed_orcids":["https://orcid.org/0000-0001-9793-6072"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaochun Zhou","raw_affiliation_strings":["Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100338438","display_name":"Peng Chen","orcid":"https://orcid.org/0000-0001-8582-7661","observed_orcids":["https://orcid.org/0000-0001-8582-7661"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peng Chen","raw_affiliation_strings":["Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019215700","display_name":"Roger F. Loring","orcid":"https://orcid.org/0000-0003-3954-9749","observed_orcids":["https://orcid.org/0000-0003-3954-9749"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roger F. Loring","raw_affiliation_strings":["Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell University Department of Chemistry and Chemical Biology, Baker Laboratory, , Ithaca, New York 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.9183,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.72121626,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"135","issue":"17","first_page":"174509","last_page":"174509"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.4936999976634979,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.4936999976634979,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10192","display_name":"Catalytic Processes in Materials Science","score":0.1256999969482422,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13187","display_name":"Diffusion and Search Dynamics","score":0.07779999822378159,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.7379999756813049},{"id":"https://openalex.org/keywords/fluorogenic-reaction","display_name":"fluorogenic reaction","score":0.7480000257492065},{"id":"https://openalex.org/keywords/single-molecule-kinetics","display_name":"single-molecule kinetics","score":0.7310000061988831},{"id":"https://openalex.org/keywords/heterogeneous-catalysis","display_name":"heterogeneous catalysis","score":0.8539999723434448},{"id":"https://openalex.org/keywords/dynamic-disorder","display_name":"dynamic disorder","score":0.7049999833106995},{"id":"https://openalex.org/keywords/product-desorption","display_name":"product desorption","score":0.7730000019073486}],"concepts":[{"id":"https://openalex.org/C151637689","wikidata":"https://www.wikidata.org/wiki/Q5318064","display_name":"Dwell time","level":2,"score":0.6593775153160095},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.567989706993103},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5182937979698181},{"id":"https://openalex.org/C135889238","wikidata":"https://www.wikidata.org/wiki/Q46276","display_name":"Kinetic energy","level":2,"score":0.5109590888023376},{"id":"https://openalex.org/C134121241","wikidata":"https://www.wikidata.org/wiki/Q899301","display_name":"Yield (engineering)","level":2,"score":0.4387704133987427},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.4209808111190796},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.38561052083969116},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.3852154612541199},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3665698170661926},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3219090700149536},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2616243064403534},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.11759236454963684},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.09209519624710083},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1063/1.3657855","doi":"https://doi.org/10.1063/1.3657855","is_oa":false,"landing_page_url":"https://doi.org/10.1063/1.3657855","pdf_url":null,"source":{"id":"https://openalex.org/S77047749","display_name":"The Journal of Chemical Physics","issn_l":"0021-9606","issn":["0021-9606","1089-7690","1520-9032"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Chemical Physics","raw_type":"journal-article"},{"id":"pmid:22070308","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22070308","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of chemical physics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4190072155","display_name":null,"funder_award_id":"DE-FG02-10ER16199","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G5779713942","display_name":"Classical and semiclassical studies of molecular motions and spectroscopy","funder_award_id":"0743299","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6626075952","display_name":null,"funder_award_id":"W911NF0910232","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G7048365490","display_name":"Single-Molecule Investigation of Nanocatalysis","funder_award_id":"0851257","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1680233762","https://openalex.org/W1973237572","https://openalex.org/W1974579817","https://openalex.org/W1981231268","https://openalex.org/W1981369125","https://openalex.org/W1983405198","https://openalex.org/W1983588639","https://openalex.org/W1989920272","https://openalex.org/W1994532328","https://openalex.org/W1997618810","https://openalex.org/W1998252865","https://openalex.org/W1998376814","https://openalex.org/W2001627350","https://openalex.org/W2008959714","https://openalex.org/W2022006299","https://openalex.org/W2023386050","https://openalex.org/W2023573388","https://openalex.org/W2025326118","https://openalex.org/W2025606037","https://openalex.org/W2027337291","https://openalex.org/W2030162988","https://openalex.org/W2030448721","https://openalex.org/W2032376057","https://openalex.org/W2032896731","https://openalex.org/W2033675143","https://openalex.org/W2040087656","https://openalex.org/W2040391135","https://openalex.org/W2045124049","https://openalex.org/W2049761345","https://openalex.org/W2051805075","https://openalex.org/W2052404294","https://openalex.org/W2054551687","https://openalex.org/W2054977363","https://openalex.org/W2061306622","https://openalex.org/W2062246937","https://openalex.org/W2063784655","https://openalex.org/W2065952168","https://openalex.org/W2076289581","https://openalex.org/W2084158739","https://openalex.org/W2084991928","https://openalex.org/W2085174160","https://openalex.org/W2088010772","https://openalex.org/W2088659153","https://openalex.org/W2094624283","https://openalex.org/W2098787719","https://openalex.org/W2101263378","https://openalex.org/W2130344693","https://openalex.org/W2131805585","https://openalex.org/W2139431996","https://openalex.org/W2141299120","https://openalex.org/W2142337964","https://openalex.org/W2146181030","https://openalex.org/W2148362226","https://openalex.org/W2149865300","https://openalex.org/W2151960001","https://openalex.org/W2155748850","https://openalex.org/W2161836601","https://openalex.org/W2164985359","https://openalex.org/W2165430487","https://openalex.org/W2166364963","https://openalex.org/W2322939815","https://openalex.org/W4240315944"],"related_works":["https://openalex.org/W2331041498","https://openalex.org/W2527854516","https://openalex.org/W2023386050","https://openalex.org/W1973237572","https://openalex.org/W3136335020","https://openalex.org/W2946876688","https://openalex.org/W2139431996","https://openalex.org/W1949335783","https://openalex.org/W2152420961","https://openalex.org/W3010262917"],"abstract_inverted_index":{"Observation":[0],"of":[1,13,27,97,118,154,191],"a":[2,10,23,28,54,65,86,130,150,160,180],"chemical":[3],"transformation":[4],"at":[5,175,201],"the":[6,18,98,116,125,133,136,142],"single-molecule":[7],"level":[8],"yields":[9],"detailed":[11],"view":[12],"kinetic":[14,161],"pathways":[15],"contributing":[16],"to":[17,85,110],"averaged":[19],"results":[20,196],"obtained":[21],"in":[22,57,68,79,104,129,141],"bulk":[24,87],"measurement.":[25,88],"Studies":[26],"fluorogenic":[29],"reaction":[30,38,211],"catalyzed":[31],"by":[32],"gold":[33],"nanoparticles":[34,46],"have":[35],"revealed":[36],"heterogeneous":[37],"dynamics":[39],"for":[40,146,159],"these":[41,168],"catalysts.":[42],"Measurements":[43],"on":[44,179],"single":[45,192],"yield":[47],"binary":[48],"trajectories":[49],"with":[50,132,163],"stochastic":[51],"transitions":[52],"between":[53],"dark":[55],"state":[56,67,81,131,144],"which":[58,69],"no":[59],"product":[60,71,217],"molecules":[61],"are":[62,102,187,205],"adsorbed":[63],"and":[64,207],"fluorescent":[66],"one":[70],"molecule":[72],"is":[73],"present.":[74],"The":[75,195],"mean":[76,92,120,126,156,184],"dwell":[77,121,127,139,157,185],"time":[78,112,128,140],"either":[80],"gives":[82],"information":[83],"corresponding":[84],"Quantifying":[89],"fluctuations":[90,174,200],"from":[91,189],"kinetics":[93],"requires":[94],"identifying":[95],"properties":[96],"fluorescence":[99],"trajectory":[100],"that":[101,135,167,198,208],"selective":[103],"emphasizing":[105],"certain":[106],"dynamic":[107,164,173],"processes":[108],"according":[109],"their":[111],"scales.":[113],"We":[114],"propose":[115],"use":[117],"constrained":[119,155],"times,":[122],"defined":[123],"as":[124],"constraint":[134],"immediately":[137],"preceding":[138],"other":[143],"is,":[145],"example,":[147],"less":[148],"than":[149],"variable":[151],"time.":[152],"Calculations":[153],"times":[158,186],"model":[162],"disorder":[165],"demonstrate":[166],"quantities":[169],"reveal":[170],"correlations":[171],"among":[172],"different":[176,202],"active":[177,203],"sites":[178,204],"multisite":[181],"catalyst.":[182],"Constrained":[183],"determined":[188],"measurements":[190],"nanoparticle":[193],"catalysis.":[194],"indicate":[197],"dynamical":[199],"correlated,":[206],"especially":[209],"rapid":[210],"events":[212],"produce":[213],"particularly":[214],"slowly":[215],"desorbing":[216],"molecules.":[218]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}