{"id":"https://openalex.org/W2005189275","doi":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","title":"Autoantibodies from primary biliary cirrhosis patients with anti-p95c antibodies bind to recombinant p97/VCP and inhibitin vitronuclear envelope assembly","display_name":"Autoantibodies from primary biliary cirrhosis patients with anti-p95c antibodies bind to recombinant p97/VCP and inhibitin vitronuclear envelope assembly","publication_year":2004,"publication_date":"2004-05-04","ids":{"openalex":"https://openalex.org/W2005189275","doi":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","mag":"2005189275","pmid":"https://pubmed.ncbi.nlm.nih.gov/15147362","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1809050"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2249.2004.02456.x","doi":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","pdf_url":"https://academic.oup.com/cei/article-pdf/136/3/568/42146485/j.1365-2249.2004.02456.x.pdf","source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/cei/article-pdf/136/3/568/42146485/j.1365-2249.2004.02456.x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110051381","display_name":"Kiyomitsu Miyachi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"K MIYACHI","raw_affiliation_strings":["Health Sciences Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Research Institute","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006137910","display_name":"Yasuhiro Hirano","orcid":"https://orcid.org/0000-0001-7339-4053","observed_orcids":["https://orcid.org/0000-0001-7339-4053"]},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y HIRANO","raw_affiliation_strings":["Niigata University, Faculty of Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Niigata University, Faculty of Science","institution_ids":["https://openalex.org/I71395657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111591309","display_name":"Tuneyoshi Horigome","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T HORIGOME","raw_affiliation_strings":["Niigata University, Faculty of Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Niigata University, Faculty of Science","institution_ids":["https://openalex.org/I71395657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016575106","display_name":"Tsuneyo Mimori","orcid":"https://orcid.org/0000-0003-0016-2053","observed_orcids":["https://orcid.org/0000-0003-0016-2053"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T MIMORI","raw_affiliation_strings":["Kyoto University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109913116","display_name":"Hiroshi Miyakawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4400573282","display_name":"Teikyo University Hospital, Mizonokuchi","ror":"https://ror.org/02p6v5z38","country_code":"JP","type":"education","lineage":["https://openalex.org/I4400573282","https://openalex.org/I87531838"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H MIYAKAWA","raw_affiliation_strings":["Teikyo Misonokuchi Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Teikyo Misonokuchi Hospital","institution_ids":["https://openalex.org/I4400573282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066640417","display_name":"Yasushi Onozuka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y ONOZUKA","raw_affiliation_strings":["Social Insurance Central Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Social Insurance Central Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110002905","display_name":"M Shibata","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M SHIBATA","raw_affiliation_strings":["East Kanto NTT Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"East Kanto NTT Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110417103","display_name":"M. Hirakata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M HIRAKATA","raw_affiliation_strings":["Keio University, School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Keio University, School of Medicine","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038986805","display_name":"Akira Suwa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"A SUWA","raw_affiliation_strings":["Keio University, School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Keio University, School of Medicine","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038758775","display_name":"Hiroo Hosaka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H HOSAKA","raw_affiliation_strings":["Yokohama Nanbu Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yokohama Nanbu Hospital","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"S MATSUSHIMA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405283918","display_name":"National Hospital Organization Yokohama Medical Center","ror":"https://ror.org/02h7rhs19","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4405283918"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S MATSUSHIMA","raw_affiliation_strings":["Yokohama Medical Center, National Hospital, Japan","Yokohama Medical Center, National Hospital, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yokohama Medical Center, National Hospital, Japan","institution_ids":["https://openalex.org/I4405283918"]},{"raw_affiliation_string":"Yokohama Medical Center, National Hospital, Japan, and","institution_ids":["https://openalex.org/I4405283918"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113961065","display_name":"Tatsuji Komatsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405283918","display_name":"National Hospital Organization Yokohama Medical Center","ror":"https://ror.org/02h7rhs19","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4405283918"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T KOMATSU","raw_affiliation_strings":["Yokohama Medical Center, National Hospital, Japan","Yokohama Medical Center, National Hospital, Japan, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yokohama Medical Center, National Hospital, Japan","institution_ids":["https://openalex.org/I4405283918"]},{"raw_affiliation_string":"Yokohama Medical Center, National Hospital, Japan, and","institution_ids":["https://openalex.org/I4405283918"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101548565","display_name":"Hiroshi Matsushima","orcid":"https://orcid.org/0000-0001-9838-0627","observed_orcids":["https://orcid.org/0000-0001-9838-0627"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H MATSUSHIMA","raw_affiliation_strings":["Health Sciences Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Research Institute","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113678394","display_name":"Raleigh Hankins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R W HANKINS","raw_affiliation_strings":["Health Sciences Research Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health Sciences Research Institute","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011458972","display_name":"Marvin J. Fritzler","orcid":"https://orcid.org/0000-0003-1652-6608","observed_orcids":["https://orcid.org/0000-0003-1652-6608"]},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M J FRITZLER","raw_affiliation_strings":["University of Calgary, Faculty of Medicine, Calgary, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Calgary, Faculty of Medicine, Calgary, Canada","institution_ids":["https://openalex.org/I168635309"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5110051381"],"corresponding_institution_ids":[],"apc_list":{"value":2894,"currency":"GBP","value_usd":3816},"apc_paid":null,"fwci":1.7694,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.84792627,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"136","issue":"3","first_page":"568","last_page":"573"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11730","display_name":"Autoimmune Bullous Skin Diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-biliary-cholangitis","display_name":"primary biliary cirrhosis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/autoantibodies","display_name":"autoantibodies","score":0.9350000023841858},{"id":"https://openalex.org/keywords/vcp-p97","display_name":"VCP/p97","score":0.9390000104904175},{"id":"https://openalex.org/keywords/valosin-containing-protein","display_name":"VCP","score":0.972000002861023},{"id":"https://openalex.org/keywords/nuclear-envelope-assembly","display_name":"nuclear envelope assembly","score":0.9419999718666077},{"id":"https://openalex.org/keywords/autoantigen-identification","display_name":"autoantigen identification","score":0.6620000004768372},{"id":"https://openalex.org/keywords/autoimmune-liver-disease","display_name":"autoimmune liver disease","score":0.5680000185966492},{"id":"https://openalex.org/keywords/nuclear-swelling","display_name":"nuclear swelling","score":0.4309999942779541},{"id":"https://openalex.org/keywords/autoantibody-titres","display_name":"autoantibody titres","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.6774835586547852},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5914762020111084},{"id":"https://openalex.org/C133229898","wikidata":"https://www.wikidata.org/wiki/Q7239484","display_name":"Precipitin","level":3,"score":0.5789071321487427},{"id":"https://openalex.org/C71829478","wikidata":"https://www.wikidata.org/wiki/Q901305","display_name":"Immunoprecipitation","level":3,"score":0.5625330209732056},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5562607049942017},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.5552034974098206},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.521247923374176},{"id":"https://openalex.org/C2780366471","wikidata":"https://www.wikidata.org/wiki/Q1072420","display_name":"Primary biliary cirrhosis","level":2,"score":0.5005905628204346},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.35482507944107056},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2300524115562439},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2285519242286682},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000074405","descriptor_name":"Valosin Containing Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000251","descriptor_name":"Adenosine Triphosphatases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000937","descriptor_name":"Antigen-Antibody Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008105","descriptor_name":"Liver Cirrhosis, Biliary","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008105","descriptor_name":"Liver Cirrhosis, Biliary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011233","descriptor_name":"Precipitin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018613","descriptor_name":"Microscopy, Confocal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018797","descriptor_name":"Cell Cycle Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1365-2249.2004.02456.x","doi":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","pdf_url":"https://academic.oup.com/cei/article-pdf/136/3/568/42146485/j.1365-2249.2004.02456.x.pdf","source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1809050","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1809050","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Exp Immunol","raw_type":"Text"},{"id":"pmid:15147362","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15147362","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental immunology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1365-2249.2004.02456.x","doi":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2249.2004.02456.x","pdf_url":"https://academic.oup.com/cei/article-pdf/136/3/568/42146485/j.1365-2249.2004.02456.x.pdf","source":{"id":"https://openalex.org/S11896317","display_name":"Clinical & Experimental Immunology","issn_l":"0009-9104","issn":["0009-9104","1365-2249"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320310537","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005189275.pdf","grobid_xml":"https://content.openalex.org/works/W2005189275.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W208521481","https://openalex.org/W1420696562","https://openalex.org/W1526505522","https://openalex.org/W1528145391","https://openalex.org/W1552738427","https://openalex.org/W1850593990","https://openalex.org/W1973058495","https://openalex.org/W1976265039","https://openalex.org/W1983848672","https://openalex.org/W1999158929","https://openalex.org/W2000612383","https://openalex.org/W2012090583","https://openalex.org/W2025155991","https://openalex.org/W2034714335","https://openalex.org/W2039545804","https://openalex.org/W2042708317","https://openalex.org/W2042752473","https://openalex.org/W2044603150","https://openalex.org/W2044778337","https://openalex.org/W2051764674","https://openalex.org/W2057608934","https://openalex.org/W2059793819","https://openalex.org/W2063187773","https://openalex.org/W2063214782","https://openalex.org/W2067911054","https://openalex.org/W2071345047","https://openalex.org/W2079352870","https://openalex.org/W2079615280","https://openalex.org/W2082029871","https://openalex.org/W2082544726","https://openalex.org/W2099990582","https://openalex.org/W2117669076","https://openalex.org/W2129962217","https://openalex.org/W2150355013","https://openalex.org/W2321394641","https://openalex.org/W2399361647","https://openalex.org/W2422099324","https://openalex.org/W4237125214","https://openalex.org/W6717362661"],"related_works":["https://openalex.org/W2063187773","https://openalex.org/W1965380773","https://openalex.org/W2097173189","https://openalex.org/W2051079941","https://openalex.org/W7096848102","https://openalex.org/W1998294654","https://openalex.org/W2068944545","https://openalex.org/W2034714335","https://openalex.org/W2138252981","https://openalex.org/W1832430407"],"abstract_inverted_index":{"We":[0,24],"have":[1,190],"reported":[2],"previously":[3,31],"that":[4,28,159,171,216],"p95c,":[5],"a":[6,34,44,145,155],"novel":[7],"95-kDa":[8],"cytosolic":[9],"protein,":[10],"was":[11,76,87,114,125,160],"the":[12,56,81,97,110,128,138,149,174,199],"target":[13],"of":[14,18,58,92,96,112,122,130,140,148,173,201],"autoantibodies":[15],"in":[16,48,66,68,71,163],"sera":[17,27,51,99,178,202],"patients":[19],"with":[20,127,179],"autoimmune":[21],"hepatic":[22],"diseases.":[23],"studied":[25],"30":[26],"were":[29,52],"shown":[30],"to":[32,54,61,79,103,153,181],"immunoprecipitate":[33],"95":[35],"kDa":[36],"protein":[37,151,158],"from":[38,101],"[(35)S]-methionine-labelled":[39],"HeLa":[40],"lysates":[41],"and":[42,105,109,188,194,197,206,218],"had":[43],"specific":[45],"precipitin":[46],"band":[47],"immunodiffusion.":[49,135],"Thirteen":[50],"available":[53],"test":[55],"ability":[57],"p95c":[59,182,187,217],"antibodies":[60,180,208],"inhibit":[62,209],"nuclear":[63,85,93,106,123,210],"envelope":[64,94,107],"assembly":[65,86,95,108,124],"an":[67,164],"vitro":[69],"assay":[70],"which":[72,84],"confocal":[73],"fluorescence":[74],"microscopy":[75],"also":[77],"used":[78,144,162],"identify":[80],"stages":[82],"at":[83,116],"inhibited.":[88],"The":[89,119],"percentage":[90,120],"inhibition":[91,121],"13":[98,175],"ranged":[100],"7%":[102],"99%":[104],"swelling":[111],"nucleus":[113],"inhibited":[115],"several":[117],"stages.":[118],"correlated":[126],"titre":[129],"anti-p95c":[131,207],"as":[132],"determined":[133],"by":[134],"To":[136],"confirm":[137],"identity":[139],"this":[141,212],"autoantigen,":[142],"we":[143],"full-length":[146],"cDNA":[147],"p97/valosin-containing":[150],"(VCP)":[152],"produce":[154],"radiolabelled":[156],"recombinant":[157,184,204],"then":[161],"immunoprecipitation":[165],"(IP)":[166],"assay.":[167],"Our":[168],"study":[169],"demonstrated":[170],"12":[172],"(93%)":[176],"human":[177],"immunoprecipitated":[183],"p97/VCP.":[185],"Because":[186],"p97":[189],"similar":[191],"molecular":[192],"masses":[193],"cell":[195],"localization,":[196],"because":[198],"majority":[200],"bind":[203],"p97/VCP":[205,219],"assembly,":[211],"is":[213],"compelling":[214],"evidence":[215],"are":[220],"identical.":[221]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}