{"id":"https://openalex.org/W2005182309","doi":"https://doi.org/10.1016/0009-3084(87)90070-3","title":"Modification of human serum low density lipoprotein by oxidation \u2014 Characterization and pathophysiological implications","display_name":"Modification of human serum low density lipoprotein by oxidation \u2014 Characterization and pathophysiological implications","publication_year":1987,"publication_date":"1987-11-01","ids":{"openalex":"https://openalex.org/W2005182309","doi":"https://doi.org/10.1016/0009-3084(87)90070-3","mag":"2005182309","pmid":"https://pubmed.ncbi.nlm.nih.gov/3319231"},"language":"en","primary_location":{"id":"doi:10.1016/0009-3084(87)90070-3","doi":"https://doi.org/10.1016/0009-3084(87)90070-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0009-3084(87)90070-3","pdf_url":null,"source":{"id":"https://openalex.org/S99078529","display_name":"Chemistry and Physics of Lipids","issn_l":"0009-3084","issn":["0009-3084","1873-2941"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry and Physics of Lipids","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2005182309"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056239518","display_name":"G\u00fcnther J\u00fcrgens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"G\u00fcnther J\u00fcrgens","raw_affiliation_strings":["Institute of Medical Biochemistry, Karl-Franzens-Universit\u00e4t Graz, Austria","Institute of Medical Biochemistry, Karl-Franzens Universitat Graz, Graz, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biochemistry, Karl-Franzens-Universit\u00e4t Graz, Austria","institution_ids":["https://openalex.org/I15766117"]},{"raw_affiliation_string":"Institute of Medical Biochemistry, Karl-Franzens Universitat Graz, Graz, Austria","institution_ids":["https://openalex.org/I15766117"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109161636","display_name":"Henry F. Hoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Henry F. Hoff","raw_affiliation_strings":["Atherosclerosis Section, Department of Brain and Vascular Research, Research Institute of the Cleveland Clinic Foundation, Cleveland, Ohio U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Atherosclerosis Section, Department of Brain and Vascular Research, Research Institute of the Cleveland Clinic Foundation, Cleveland, Ohio U.S.A","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108789765","display_name":"Guy M. Chisolm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I4405287411","display_name":"Cleveland Clinic Research","ror":"https://ror.org/053229s83","country_code":"US","type":"facility","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guy M. Chisolm","raw_affiliation_strings":["Atherosclerosis Section, Department of Brain and Vascular Research, Research Institute of the Cleveland Clinic Foundation, Cleveland, Ohio U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Atherosclerosis Section, Department of Brain and Vascular Research, Research Institute of the Cleveland Clinic Foundation, Cleveland, Ohio U.S.A","institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I4405287411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111860735","display_name":"Hermann Esterbauer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I15766117","display_name":"University of Graz","ror":"https://ror.org/01faaaf77","country_code":"AT","type":"education","lineage":["https://openalex.org/I15766117"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Hermann Esterbauer","raw_affiliation_strings":["Institute of Biochemistry, Karl-Franzens-Universit\u00e4t Graz, Graz Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biochemistry, Karl-Franzens-Universit\u00e4t Graz, Graz Austria","institution_ids":["https://openalex.org/I15766117"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056239518"],"corresponding_institution_ids":["https://openalex.org/I15766117"],"apc_list":{"value":3870,"currency":"USD","value_usd":3870},"apc_paid":null,"fwci":2.8078,"has_fulltext":false,"cited_by_count":398,"citation_normalized_percentile":{"value":0.92015209,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"45","issue":"2-4","first_page":"315","last_page":"336"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.4343000054359436,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.4343000054359436,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.4065000116825104,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.1281999945640564,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxidized-ldl","display_name":"oxidized LDL","score":0.9390000104904175},{"id":"https://openalex.org/keywords/free-radical-oxidation","display_name":"free radical oxidation","score":0.8180000185966492},{"id":"https://openalex.org/keywords/apolipoprotein-b","display_name":"apolipoprotein B","score":0.7519999742507935},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.843999981880188},{"id":"https://openalex.org/keywords/vitamin-e-depletion","display_name":"vitamin E depletion","score":0.7179999947547913},{"id":"https://openalex.org/keywords/scavenger-receptors","display_name":"scavenger receptors","score":0.6949999928474426},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8759999871253967},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8299999833106995},{"id":"https://openalex.org/keywords/monocyte-chemotaxis","display_name":"monocyte chemotaxis","score":0.843999981880188},{"id":"https://openalex.org/keywords/platelet-derived-growth-factor","display_name":"platelet-derived growth factor","score":0.902999997138977},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.921999990940094},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.7630000114440918},{"id":"https://openalex.org/keywords/smooth-muscle-cells","display_name":"smooth muscle cells","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9275806546211243},{"id":"https://openalex.org/C41443022","wikidata":"https://www.wikidata.org/wiki/Q27796666","display_name":"Scavenger receptor","level":4,"score":0.7096152901649475},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.6165418028831482},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5915282964706421},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.5614879131317139},{"id":"https://openalex.org/C2779620165","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Low-density lipoprotein","level":3,"score":0.553703248500824},{"id":"https://openalex.org/C8004288","wikidata":"https://www.wikidata.org/wiki/Q2619230","display_name":"Intermediate-density lipoprotein","level":5,"score":0.4570155441761017},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.30155444145202637},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.27069520950317383}],"mesh":[{"descriptor_ui":"D005609","descriptor_name":"Free Radicals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008077","descriptor_name":"Lipoproteins, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0009-3084(87)90070-3","doi":"https://doi.org/10.1016/0009-3084(87)90070-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0009-3084(87)90070-3","pdf_url":null,"source":{"id":"https://openalex.org/S99078529","display_name":"Chemistry and Physics of Lipids","issn_l":"0009-3084","issn":["0009-3084","1873-2941"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry and Physics of Lipids","raw_type":"journal-article"},{"id":"pmid:3319231","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3319231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry and physics of lipids","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5880499879","display_name":"Mechanisms linking inflammation, metabolism, and atherosclerosis.","funder_award_id":"P01HL029582","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":101,"referenced_works":["https://openalex.org/W18245585","https://openalex.org/W61911447","https://openalex.org/W104468390","https://openalex.org/W149019623","https://openalex.org/W236822603","https://openalex.org/W1483555478","https://openalex.org/W1487164341","https://openalex.org/W1490632139","https://openalex.org/W1516730660","https://openalex.org/W1534702626","https://openalex.org/W1541126435","https://openalex.org/W1546909579","https://openalex.org/W1604900522","https://openalex.org/W1871621847","https://openalex.org/W1920171370","https://openalex.org/W1935057314","https://openalex.org/W1968103962","https://openalex.org/W1970496775","https://openalex.org/W1971900576","https://openalex.org/W1978896699","https://openalex.org/W1984393490","https://openalex.org/W1985016196","https://openalex.org/W1986344428","https://openalex.org/W1987828976","https://openalex.org/W1988003237","https://openalex.org/W1991035131","https://openalex.org/W1995490285","https://openalex.org/W1995696342","https://openalex.org/W1995818837","https://openalex.org/W2000239031","https://openalex.org/W2003599469","https://openalex.org/W2007424719","https://openalex.org/W2008819827","https://openalex.org/W2017315967","https://openalex.org/W2022149465","https://openalex.org/W2028475330","https://openalex.org/W2033931529","https://openalex.org/W2035612792","https://openalex.org/W2036660517","https://openalex.org/W2040847281","https://openalex.org/W2046715847","https://openalex.org/W2048342807","https://openalex.org/W2048686621","https://openalex.org/W2052467614","https://openalex.org/W2053130274","https://openalex.org/W2053357004","https://openalex.org/W2055095303","https://openalex.org/W2055529538","https://openalex.org/W2057401811","https://openalex.org/W2058841561","https://openalex.org/W2061658519","https://openalex.org/W2064680640","https://openalex.org/W2065790541","https://openalex.org/W2070951814","https://openalex.org/W2073781371","https://openalex.org/W2073961509","https://openalex.org/W2075558237","https://openalex.org/W2077708148","https://openalex.org/W2082658073","https://openalex.org/W2083267747","https://openalex.org/W2085600362","https://openalex.org/W2086643536","https://openalex.org/W2087887854","https://openalex.org/W2092202672","https://openalex.org/W2092883171","https://openalex.org/W2096766134","https://openalex.org/W2096808813","https://openalex.org/W2105976663","https://openalex.org/W2109068111","https://openalex.org/W2110569594","https://openalex.org/W2111171453","https://openalex.org/W2113553969","https://openalex.org/W2121972309","https://openalex.org/W2123805157","https://openalex.org/W2127071379","https://openalex.org/W2128488935","https://openalex.org/W2129613538","https://openalex.org/W2129962657","https://openalex.org/W2139835405","https://openalex.org/W2140328938","https://openalex.org/W2141605053","https://openalex.org/W2159157018","https://openalex.org/W2161188230","https://openalex.org/W2162458714","https://openalex.org/W2166102788","https://openalex.org/W2168971665","https://openalex.org/W2181693634","https://openalex.org/W2188707394","https://openalex.org/W2205448180","https://openalex.org/W2218255345","https://openalex.org/W2309615146","https://openalex.org/W2320785245","https://openalex.org/W2321228901","https://openalex.org/W2336492617","https://openalex.org/W2395778722","https://openalex.org/W2398161220","https://openalex.org/W2398455818","https://openalex.org/W2402878181","https://openalex.org/W2417519586","https://openalex.org/W4248097812","https://openalex.org/W4402015178"],"related_works":["https://openalex.org/W2044900626","https://openalex.org/W2403087287","https://openalex.org/W2121972309","https://openalex.org/W1125403992","https://openalex.org/W1223371499","https://openalex.org/W250302887","https://openalex.org/W2104573407","https://openalex.org/W2418587812","https://openalex.org/W1984393490","https://openalex.org/W1970211770"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
