{"id":"https://openalex.org/W2005180114","doi":"https://doi.org/10.1016/0888-7543(95)80090-9","title":"Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human","display_name":"Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human","publication_year":1995,"publication_date":"1995-03-01","ids":{"openalex":"https://openalex.org/W2005180114","doi":"https://doi.org/10.1016/0888-7543(95)80090-9","mag":"2005180114","pmid":"https://pubmed.ncbi.nlm.nih.gov/7782070"},"language":"en","primary_location":{"id":"doi:10.1016/0888-7543(95)80090-9","doi":"https://doi.org/10.1016/0888-7543(95)80090-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0888-7543(95)80090-9","pdf_url":null,"source":{"id":"https://openalex.org/S146035217","display_name":"Genomics","issn_l":"0888-7543","issn":["0888-7543","1089-8646"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088427605","display_name":"Majambu Mbikay","orcid":"https://orcid.org/0000-0003-4854-6507","observed_orcids":["https://orcid.org/0000-0003-4854-6507"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]},{"id":"https://openalex.org/I4210158752","display_name":"Montreal Clinical Research Institute","ror":"https://ror.org/05m8pzq90","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA","US"],"is_corresponding":true,"raw_author_name":"Majambu Mbikay","raw_affiliation_strings":["Jackson Laboratory, Bar Harbor, Maine 04609, USA","Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7","The Jackson Laboratory, Bar Harbor, Maine 04609, University of Montreal, Montreal, Quebec, Canada H2W 1R7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jackson Laboratory, Bar Harbor, Maine 04609, USA","institution_ids":["https://openalex.org/I4210115256"]},{"raw_affiliation_string":"Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7","institution_ids":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]},{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, Maine 04609, University of Montreal, Montreal, Quebec, Canada H2W 1R7","institution_ids":["https://openalex.org/I4210115256","https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090995081","display_name":"Nabil Georges Seidah","orcid":"https://orcid.org/0000-0001-6503-9342","observed_orcids":["https://orcid.org/0000-0001-6503-9342"]},"institutions":[{"id":"https://openalex.org/I4210158752","display_name":"Montreal Clinical Research Institute","ror":"https://ror.org/05m8pzq90","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nabil G. Seidah","raw_affiliation_strings":["Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7","institution_ids":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009035456","display_name":"Michel Chr\u00e9tien","orcid":"https://orcid.org/0000-0002-8588-4460","observed_orcids":["https://orcid.org/0000-0002-8588-4460"]},"institutions":[{"id":"https://openalex.org/I4210158752","display_name":"Montreal Clinical Research Institute","ror":"https://ror.org/05m8pzq90","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Michel Chr\u00e9tien","raw_affiliation_strings":["Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada H2W 1R7","institution_ids":["https://openalex.org/I4210158752","https://openalex.org/I70931966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065488747","display_name":"Elizabeth M. Simpson","orcid":"https://orcid.org/0000-0002-0654-4303","observed_orcids":["https://orcid.org/0000-0002-0654-4303"]},"institutions":[{"id":"https://openalex.org/I4210115256","display_name":"Jackson Laboratory","ror":"https://ror.org/021sy4w91","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Elizabeth M. Simpson","raw_affiliation_strings":["The Jackson Laboratory, Bar Harbor, Maine 04609, University of Montreal, Montreal, Quebec, Canada H2W 1R7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Bar Harbor, Maine 04609, University of Montreal, Montreal, Quebec, Canada H2W 1R7","institution_ids":["https://openalex.org/I4210115256","https://openalex.org/I70931966"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5088427605"],"corresponding_institution_ids":["https://openalex.org/I4210115256","https://openalex.org/I4210158752","https://openalex.org/I70931966"],"apc_list":{"value":2980,"currency":"USD","value_usd":2980},"apc_paid":null,"fwci":1.3182,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.80673181,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"26","issue":"1","first_page":"123","last_page":"129"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.31470000743865967,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.31470000743865967,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.22660000622272491,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.051100000739097595,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/proprotein-convertases","display_name":"proprotein convertases","score":0.984000027179718},{"id":"https://openalex.org/keywords/pc4","display_name":"PC4","score":0.8610000014305115},{"id":"https://openalex.org/keywords/pc5","display_name":"PC5","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pace4","display_name":"PACE4","score":0.9929999709129333},{"id":"https://openalex.org/keywords/pcsk5","display_name":"PCSK5","score":1.0},{"id":"https://openalex.org/keywords/pcsk6","display_name":"PCSK6","score":1.0},{"id":"https://openalex.org/keywords/furin","display_name":"furin","score":0.921999990940094},{"id":"https://openalex.org/keywords/chromosome-mapping","display_name":"chromosome mapping","score":0.6899999976158142},{"id":"https://openalex.org/keywords/mouse-chromosome-10","display_name":"mouse chromosome 10","score":0.8370000123977661},{"id":"https://openalex.org/keywords/mouse-chromosome-19","display_name":"mouse chromosome 19","score":0.9509999752044678},{"id":"https://openalex.org/keywords/mouse-chromosome-7","display_name":"mouse chromosome 7","score":0.9980000257492065},{"id":"https://openalex.org/keywords/human-chromosome-19","display_name":"chromosome 19","score":0.9800000190734863},{"id":"https://openalex.org/keywords/chromosome-9","display_name":"chromosome 9","score":0.9879999756813049},{"id":"https://openalex.org/keywords/imprinting","display_name":"imprinting","score":0.6639999747276306},{"id":"https://openalex.org/keywords/adipsin","display_name":"adipsin","score":0.5820000171661377},{"id":"https://openalex.org/keywords/anti-mullerian-hormone","display_name":"anti-M\u00fcllerian hormone","score":0.9629999995231628},{"id":"https://openalex.org/keywords/annexin-a1","display_name":"annexin A1","score":0.9860000014305115}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8270507454872131},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.7839411497116089},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6351596713066101},{"id":"https://openalex.org/C109748351","wikidata":"https://www.wikidata.org/wiki/Q657319","display_name":"Chromosome 7 (human)","level":4,"score":0.5543703436851501},{"id":"https://openalex.org/C137555145","wikidata":"https://www.wikidata.org/wiki/Q753218","display_name":"Chromosome 21","level":4,"score":0.5055739879608154},{"id":"https://openalex.org/C122735190","wikidata":"https://www.wikidata.org/wiki/Q715789","display_name":"Gene mapping","level":4,"score":0.4951838552951813},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4931146800518036},{"id":"https://openalex.org/C165237769","wikidata":"https://www.wikidata.org/wiki/Q765245","display_name":"Chromosome 15","level":4,"score":0.45124930143356323},{"id":"https://openalex.org/C174553679","wikidata":"https://www.wikidata.org/wiki/Q4388138","display_name":"Gene map","level":5,"score":0.4355143904685974},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4233933091163635},{"id":"https://openalex.org/C167752854","wikidata":"https://www.wikidata.org/wiki/Q220677","display_name":"Chromosome 17 (human)","level":4,"score":0.4199722409248352},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.3268964886665344}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002884","descriptor_name":"Chromosomes, Human, Pair 15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002888","descriptor_name":"Chromosomes, Human, Pair 19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002899","descriptor_name":"Chromosomes, Human, Pair 9","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006239","descriptor_name":"Haplotypes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006822","descriptor_name":"Hybrid Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012150","descriptor_name":"Polymorphism, Restriction Fragment Length","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013381","descriptor_name":"Subtilisins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D043484","descriptor_name":"Proprotein Convertases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045702","descriptor_name":"Proprotein Convertase 5","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0888-7543(95)80090-9","doi":"https://doi.org/10.1016/0888-7543(95)80090-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0888-7543(95)80090-9","pdf_url":null,"source":{"id":"https://openalex.org/S146035217","display_name":"Genomics","issn_l":"0888-7543","issn":["0888-7543","1089-8646"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics","raw_type":"journal-article"},{"id":"pmid:7782070","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7782070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G44229997","display_name":null,"funder_award_id":"CA44196","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320324195","display_name":"Medical Research Council Canada","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W400688913","https://openalex.org/W1501424340","https://openalex.org/W1508932783","https://openalex.org/W1510487353","https://openalex.org/W1563977056","https://openalex.org/W1568930548","https://openalex.org/W1578843331","https://openalex.org/W1583922438","https://openalex.org/W1593390085","https://openalex.org/W1812255132","https://openalex.org/W1969935465","https://openalex.org/W1973041446","https://openalex.org/W1973416843","https://openalex.org/W1975096426","https://openalex.org/W1980284138","https://openalex.org/W1984247755","https://openalex.org/W1989873968","https://openalex.org/W1990887736","https://openalex.org/W1995563543","https://openalex.org/W2014669590","https://openalex.org/W2025089318","https://openalex.org/W2031196190","https://openalex.org/W2031937019","https://openalex.org/W2035930617","https://openalex.org/W2040633136","https://openalex.org/W2042485106","https://openalex.org/W2045288483","https://openalex.org/W2054328794","https://openalex.org/W2070610372","https://openalex.org/W2078210518","https://openalex.org/W2080891422","https://openalex.org/W2082012658","https://openalex.org/W2099336487","https://openalex.org/W2180906670","https://openalex.org/W2233592850","https://openalex.org/W2404745717","https://openalex.org/W2411978009","https://openalex.org/W2412671923","https://openalex.org/W2576734941","https://openalex.org/W2589071211","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4237894187","https://openalex.org/W1983946794","https://openalex.org/W2042485106","https://openalex.org/W1980284138","https://openalex.org/W2043328403","https://openalex.org/W1990887736","https://openalex.org/W2042674588","https://openalex.org/W1964037924","https://openalex.org/W1971075195","https://openalex.org/W2042041658"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}