{"id":"https://openalex.org/W2005177932","doi":"https://doi.org/10.1530/jrf.0.0270259","title":"PROTEASE ACTIVITY IN RABBIT UTERINE SECRETION 24 HOURS BEFORE IMPLANTATION","display_name":"PROTEASE ACTIVITY IN RABBIT UTERINE SECRETION 24 HOURS BEFORE IMPLANTATION","publication_year":1971,"publication_date":"1971-11-01","ids":{"openalex":"https://openalex.org/W2005177932","doi":"https://doi.org/10.1530/jrf.0.0270259","mag":"2005177932","pmid":"https://pubmed.ncbi.nlm.nih.gov/5125011"},"language":"en","primary_location":{"id":"doi:10.1530/jrf.0.0270259","doi":"https://doi.org/10.1530/jrf.0.0270259","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0270259","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/27/2/jrf_27_2_014.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/27/2/jrf_27_2_014.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108292804","display_name":"C. Kirchner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]},{"id":"https://openalex.org/I4210089242","display_name":"D\u00fcsseldorf University Hospital","ror":"https://ror.org/006k2kk72","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210089242"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C. KIRCHNER","raw_affiliation_strings":["Zoological Institute of the University Marburg and Dermatological Clinic of the University Duesseldorf Germany","Dermatological Clinic of the University Duesseldorf Germany","Zoological Institute of the University Marburg and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zoological Institute of the University Marburg and Dermatological Clinic of the University Duesseldorf Germany","institution_ids":[]},{"raw_affiliation_string":"Dermatological Clinic of the University Duesseldorf Germany","institution_ids":["https://openalex.org/I4210089242"]},{"raw_affiliation_string":"Zoological Institute of the University Marburg and","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027896031","display_name":"Claudius Hirschh\u00e4user","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]},{"id":"https://openalex.org/I4210089242","display_name":"D\u00fcsseldorf University Hospital","ror":"https://ror.org/006k2kk72","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210089242"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"C. HIRSCHH\u00c4USER","raw_affiliation_strings":["Dermatological Clinic of the University Duesseldorf Germany","Zoological Institute of the University Marburg and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dermatological Clinic of the University Duesseldorf Germany","institution_ids":["https://openalex.org/I4210089242"]},{"raw_affiliation_string":"Zoological Institute of the University Marburg and","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000522154","display_name":"Manfred Kionke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]},{"id":"https://openalex.org/I4210089242","display_name":"D\u00fcsseldorf University Hospital","ror":"https://ror.org/006k2kk72","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210089242"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M. KIONKE","raw_affiliation_strings":["Zoological Institute of the University Marburg and Dermatological Clinic of the University Duesseldorf Germany","Dermatological Clinic of the University Duesseldorf Germany","Zoological Institute of the University Marburg and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zoological Institute of the University Marburg and Dermatological Clinic of the University Duesseldorf Germany","institution_ids":[]},{"raw_affiliation_string":"Dermatological Clinic of the University Duesseldorf Germany","institution_ids":["https://openalex.org/I4210089242"]},{"raw_affiliation_string":"Zoological Institute of the University Marburg and","institution_ids":["https://openalex.org/I161103922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9062,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.73349899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"27","issue":"2","first_page":"259","last_page":"NP"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.9682999849319458,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.021700000390410423,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uterine-secretions","display_name":"uterine secretions","score":0.8460000157356262},{"id":"https://openalex.org/keywords/proteolytic-activity","display_name":"proteolytic activity","score":0.9739999771118164},{"id":"https://openalex.org/keywords/rabbit-uterus","display_name":"rabbit uterus","score":0.671999990940094},{"id":"https://openalex.org/keywords/implantation","display_name":"implantation","score":0.8519999980926514},{"id":"https://openalex.org/keywords/embryo-implantation","display_name":"embryo implantation","score":0.9070000052452087},{"id":"https://openalex.org/keywords/preimplantation-period","display_name":"preimplantation period","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.8269094228744507},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.6683699488639832},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.5948716998100281},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.5802031755447388},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.5301117897033691},{"id":"https://openalex.org/C2779884254","wikidata":"https://www.wikidata.org/wiki/Q492162","display_name":"Rabbit (cipher)","level":2,"score":0.5295549035072327},{"id":"https://openalex.org/C3018936355","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Neutral protease","level":4,"score":0.5065497159957886},{"id":"https://openalex.org/C2779742232","wikidata":"https://www.wikidata.org/wiki/Q839508","display_name":"Endometrium","level":2,"score":0.48316115140914917},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4722651243209839},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.46834370493888855},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45532822608947754},{"id":"https://openalex.org/C2779066055","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Uterus","level":2,"score":0.448181688785553},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3946702182292938},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3799736201763153},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3297358453273773},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.30762365460395813},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24442431330680847},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.09187522530555725},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000179","descriptor_name":"Acrylates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002850","descriptor_name":"Chromatography, Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002852","descriptor_name":"Chromatography, Ion Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004589","descriptor_name":"Electrophoresis, Disc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004971","descriptor_name":"Estrus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005612","descriptor_name":"Freeze Drying","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005780","descriptor_name":"Gelatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005782","descriptor_name":"Gels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010064","descriptor_name":"Embryo Implantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010447","descriptor_name":"Peptide Hydrolases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1530/jrf.0.0270259","doi":"https://doi.org/10.1530/jrf.0.0270259","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0270259","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/27/2/jrf_27_2_014.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},{"id":"pmid:5125011","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5125011","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of reproduction and fertility","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.511.7388","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.511.7388","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.reproduction-online.org/content/27/2/259.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1530/jrf.0.0270259","doi":"https://doi.org/10.1530/jrf.0.0270259","is_oa":true,"landing_page_url":"https://doi.org/10.1530/jrf.0.0270259","pdf_url":"https://rep.bioscientifica.com/downloadpdf/journals/rep/27/2/jrf_27_2_014.pdf","source":{"id":"https://openalex.org/S28473761","display_name":"Reproduction","issn_l":"1470-1626","issn":["1470-1626","1741-7899"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005177932.pdf","grobid_xml":"https://content.openalex.org/works/W2005177932.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W121900260","https://openalex.org/W1809187462","https://openalex.org/W1983169362","https://openalex.org/W2067317165"],"related_works":["https://openalex.org/W2281436197","https://openalex.org/W2395573914","https://openalex.org/W2005767999","https://openalex.org/W122832104","https://openalex.org/W2319095684","https://openalex.org/W2034294657","https://openalex.org/W2096212616","https://openalex.org/W118723464","https://openalex.org/W2208644118","https://openalex.org/W4241602075"],"abstract_inverted_index":{"Summary.":[0],"Protease":[1],"activity":[2,19],"in":[3,23],"rabbit":[4],"uterine":[5,33],"secretion,":[6],"24":[7],"hr":[8],"before":[9],"implantation,":[10],"was":[11],"demonstrated":[12],"by":[13],"film":[14],"gelatine":[15],"lysis.":[16],"The":[17,27],"enzyme":[18],"could":[20],"be":[21],"localized":[22],"the":[24,36,39],"\u03b2-glycoprotein":[25],"fraction.":[26],"authors":[28],"assume":[29],"a":[30],"relation":[31],"between":[32],"protease":[34],"and":[35],"implantation":[37],"of":[38],"blastocyst.":[40]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}