{"id":"https://openalex.org/W2005166817","doi":"https://doi.org/10.1016/s0011-3840(79)80011-8","title":"Secondary bacterial peritonitis: The biologic basis of treatment","display_name":"Secondary bacterial peritonitis: The biologic basis of treatment","publication_year":1979,"publication_date":"1979-10-01","ids":{"openalex":"https://openalex.org/W2005166817","doi":"https://doi.org/10.1016/s0011-3840(79)80011-8","mag":"2005166817","pmid":"https://pubmed.ncbi.nlm.nih.gov/387340"},"language":"en","primary_location":{"id":"doi:10.1016/s0011-3840(79)80011-8","doi":"https://doi.org/10.1016/s0011-3840(79)80011-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0011-3840(79)80011-8","pdf_url":null,"source":{"id":"https://openalex.org/S84847770","display_name":"Current Problems in Surgery","issn_l":"0011-3840","issn":["0011-3840","1535-6337"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Problems in Surgery","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110894937","display_name":"Toni Hau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toni Hau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110060580","display_name":"David H. Ahrenholz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David H. Ahrenholz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108903982","display_name":"Richard L. Simmons","orcid":"https://orcid.org/0000-0001-6735-9913","observed_orcids":["https://orcid.org/0000-0001-6735-9913"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard L. Simmons","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2780,"currency":"USD","value_usd":2780},"apc_paid":null,"fwci":1.1667,"has_fulltext":false,"cited_by_count":177,"citation_normalized_percentile":{"value":0.71428571,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"16","issue":"10","first_page":"1","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.44429999589920044,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.44429999589920044,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.2992999851703644,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.08820000290870667,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/secondary-bacterial-peritonitis","display_name":"secondary bacterial peritonitis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/chronic-peritonitis","display_name":"chronic peritonitis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.8669999837875366},{"id":"https://openalex.org/keywords/anti-il-10-antibody","display_name":"anti-IL-10 antibody","score":0.9440000057220459},{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.9340000152587891},{"id":"https://openalex.org/keywords/neutrophil-accumulation","display_name":"neutrophil accumulation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.9290000200271606},{"id":"https://openalex.org/keywords/bacterial-clearance","display_name":"bacterial clearance","score":0.8679999709129333},{"id":"https://openalex.org/keywords/host-immune-response","display_name":"host immune response","score":0.7900000214576721},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.414000004529953},{"id":"https://openalex.org/keywords/gentamicin","display_name":"gentamicin","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C2780199535","wikidata":"https://www.wikidata.org/wiki/Q223102","display_name":"Peritonitis","level":2,"score":0.7930060625076294},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7893517017364502},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.7604283094406128},{"id":"https://openalex.org/C2775832221","wikidata":"https://www.wikidata.org/wiki/Q422482","display_name":"Gentamicin","level":3,"score":0.6310011744499207},{"id":"https://openalex.org/C2779116282","wikidata":"https://www.wikidata.org/wiki/Q131854","display_name":"Klebsiella","level":4,"score":0.6212855577468872},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5497005581855774},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5273830890655518},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4682192802429199},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4501877725124359},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4192243814468384},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.41075512766838074},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26746106147766113},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1511927843093872},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.11756962537765503},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002981","descriptor_name":"Clindamycin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007507","descriptor_name":"Therapeutic Irrigation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010537","descriptor_name":"Peritoneum","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010538","descriptor_name":"Peritonitis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013369","descriptor_name":"Subphrenic Abscess","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013369","descriptor_name":"Subphrenic Abscess","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0011-3840(79)80011-8","doi":"https://doi.org/10.1016/s0011-3840(79)80011-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0011-3840(79)80011-8","pdf_url":null,"source":{"id":"https://openalex.org/S84847770","display_name":"Current Problems in Surgery","issn_l":"0011-3840","issn":["0011-3840","1535-6337"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Problems in Surgery","raw_type":"journal-article"},{"id":"pmid:387340","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/387340","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current problems in surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":162,"referenced_works":["https://openalex.org/W22081447","https://openalex.org/W44419167","https://openalex.org/W73077642","https://openalex.org/W85194748","https://openalex.org/W163244200","https://openalex.org/W171664310","https://openalex.org/W215088563","https://openalex.org/W813844500","https://openalex.org/W1486596698","https://openalex.org/W1486678714","https://openalex.org/W1488071304","https://openalex.org/W1505647794","https://openalex.org/W1523370258","https://openalex.org/W1548788093","https://openalex.org/W1551228423","https://openalex.org/W1562572015","https://openalex.org/W1571636720","https://openalex.org/W1595569199","https://openalex.org/W1596213316","https://openalex.org/W1607744318","https://openalex.org/W1622744560","https://openalex.org/W1652316892","https://openalex.org/W1828555478","https://openalex.org/W1891285339","https://openalex.org/W1898285415","https://openalex.org/W1963688157","https://openalex.org/W1965613740","https://openalex.org/W1965887484","https://openalex.org/W1967227805","https://openalex.org/W1968235008","https://openalex.org/W1968758209","https://openalex.org/W1973820893","https://openalex.org/W1975314474","https://openalex.org/W1976430547","https://openalex.org/W1986365503","https://openalex.org/W1987271080","https://openalex.org/W1993981848","https://openalex.org/W1998262692","https://openalex.org/W1998396521","https://openalex.org/W1999574510","https://openalex.org/W2000601630","https://openalex.org/W2001742314","https://openalex.org/W2002159053","https://openalex.org/W2004061569","https://openalex.org/W2016102249","https://openalex.org/W2023154641","https://openalex.org/W2023886887","https://openalex.org/W2024275427","https://openalex.org/W2024286715","https://openalex.org/W2026235476","https://openalex.org/W2026745572","https://openalex.org/W2027847342","https://openalex.org/W2028479087","https://openalex.org/W2029504229","https://openalex.org/W2035820635","https://openalex.org/W2036872389","https://openalex.org/W2037353286","https://openalex.org/W2038095674","https://openalex.org/W2040660587","https://openalex.org/W2049722044","https://openalex.org/W2051542807","https://openalex.org/W2053760222","https://openalex.org/W2054202140","https://openalex.org/W2057320646","https://openalex.org/W2057601505","https://openalex.org/W2058561120","https://openalex.org/W2058834053","https://openalex.org/W2059486898","https://openalex.org/W2062085924","https://openalex.org/W2063073670","https://openalex.org/W2065510401","https://openalex.org/W2065678867","https://openalex.org/W2066666045","https://openalex.org/W2066957627","https://openalex.org/W2068151609","https://openalex.org/W2070144094","https://openalex.org/W2076971181","https://openalex.org/W2077934518","https://openalex.org/W2078701019","https://openalex.org/W2079423626","https://openalex.org/W2080864548","https://openalex.org/W2084922023","https://openalex.org/W2085657694","https://openalex.org/W2085835712","https://openalex.org/W2089341319","https://openalex.org/W2091967767","https://openalex.org/W2093559215","https://openalex.org/W2095035439","https://openalex.org/W2097405719","https://openalex.org/W2098033555","https://openalex.org/W2099086253","https://openalex.org/W2114161580","https://openalex.org/W2115631282","https://openalex.org/W2118885210","https://openalex.org/W2119704169","https://openalex.org/W2123432499","https://openalex.org/W2128040436","https://openalex.org/W2136818130","https://openalex.org/W2137814851","https://openalex.org/W2138737466","https://openalex.org/W2139347335","https://openalex.org/W2144982457","https://openalex.org/W2153565837","https://openalex.org/W2164332181","https://openalex.org/W2167793467","https://openalex.org/W2208191392","https://openalex.org/W2226607332","https://openalex.org/W2233700956","https://openalex.org/W2285763371","https://openalex.org/W2314521522","https://openalex.org/W2325409000","https://openalex.org/W2333562334","https://openalex.org/W2335460732","https://openalex.org/W2337380454","https://openalex.org/W2342131823","https://openalex.org/W2396197345","https://openalex.org/W2397126588","https://openalex.org/W2398185343","https://openalex.org/W2399386951","https://openalex.org/W2399786089","https://openalex.org/W2402130958","https://openalex.org/W2402825124","https://openalex.org/W2403255738","https://openalex.org/W2405770165","https://openalex.org/W2406521277","https://openalex.org/W2408695535","https://openalex.org/W2411091176","https://openalex.org/W2411947087","https://openalex.org/W2413034916","https://openalex.org/W2415022196","https://openalex.org/W2416588962","https://openalex.org/W2418637069","https://openalex.org/W2419646808","https://openalex.org/W2422167823","https://openalex.org/W2425037681","https://openalex.org/W2426592118","https://openalex.org/W2434462555","https://openalex.org/W2436968320","https://openalex.org/W2461524334","https://openalex.org/W2462244846","https://openalex.org/W2463753825","https://openalex.org/W2470877470","https://openalex.org/W2472719845","https://openalex.org/W2473648369","https://openalex.org/W2502228213","https://openalex.org/W2542201181","https://openalex.org/W2592808188","https://openalex.org/W2596885835","https://openalex.org/W2783145767","https://openalex.org/W2794473183","https://openalex.org/W2976878719","https://openalex.org/W3021540719","https://openalex.org/W4229599606","https://openalex.org/W4231178418","https://openalex.org/W4236006014","https://openalex.org/W4237778250","https://openalex.org/W4243736118","https://openalex.org/W4250433798","https://openalex.org/W4252219140","https://openalex.org/W4285719527","https://openalex.org/W4313309063","https://openalex.org/W6813360369"],"related_works":["https://openalex.org/W1967324780","https://openalex.org/W1549542172","https://openalex.org/W2144824088","https://openalex.org/W2114155585","https://openalex.org/W1903746872","https://openalex.org/W1938627047","https://openalex.org/W2041408258","https://openalex.org/W2148739955","https://openalex.org/W2041097059","https://openalex.org/W2041697294"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
