{"id":"https://openalex.org/W2005162085","doi":"https://doi.org/10.2214/ajr.143.5.1015","title":"Magnetic resonance imaging of multiple sclerosis: a study of pulse-technique efficacy","display_name":"Magnetic resonance imaging of multiple sclerosis: a study of pulse-technique efficacy","publication_year":1984,"publication_date":"1984-11-01","ids":{"openalex":"https://openalex.org/W2005162085","doi":"https://doi.org/10.2214/ajr.143.5.1015","mag":"2005162085","pmid":"https://pubmed.ncbi.nlm.nih.gov/6333143"},"language":"en","primary_location":{"id":"doi:10.2214/ajr.143.5.1015","doi":"https://doi.org/10.2214/ajr.143.5.1015","is_oa":false,"landing_page_url":"https://doi.org/10.2214/ajr.143.5.1015","pdf_url":null,"source":{"id":"https://openalex.org/S161085503","display_name":"American Journal of Roentgenology","issn_l":"0002-9580","issn":["0002-9580","0361-803X","1546-3141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315781","host_organization_name":"American Roentgen Ray Society","host_organization_lineage":["https://openalex.org/P4310315781"],"host_organization_lineage_names":["American Roentgen Ray Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Roentgenology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088392981","display_name":"Val Murray Runge","orcid":"https://orcid.org/0000-0002-2321-3338","observed_orcids":["https://orcid.org/0000-0002-2321-3338"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"VM Runge","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015064085","display_name":"AC Price","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"AC Price","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018338106","display_name":"Howard S. Kirshner","orcid":"https://orcid.org/0000-0002-0188-3306","observed_orcids":["https://orcid.org/0000-0002-0188-3306"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"HS Kirshner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001220646","display_name":"J H Allen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JH Allen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058006927","display_name":"C. Leon Partain","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"CL Partain","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110109290","display_name":"A. Everett James","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"AE James","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.5848,"has_fulltext":false,"cited_by_count":82,"citation_normalized_percentile":{"value":0.98169782,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"143","issue":"5","first_page":"1015","last_page":"1026"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-sclerosis","display_name":"multiple sclerosis","score":1.0},{"id":"https://openalex.org/keywords/proton-magnetic-resonance-imaging","display_name":"proton magnetic resonance imaging","score":0.9309999942779541},{"id":"https://openalex.org/keywords/t2-weighted-spin-echo","display_name":"T2-weighted spin echo","score":0.9279999732971191},{"id":"https://openalex.org/keywords/inversion-recovery","display_name":"inversion recovery","score":0.8840000033378601},{"id":"https://openalex.org/keywords/white-matter-lesions","display_name":"white matter lesions","score":0.6890000104904175},{"id":"https://openalex.org/keywords/brainstem-lesions","display_name":"brainstem lesions","score":0.9470000267028809},{"id":"https://openalex.org/keywords/brain-lesions","display_name":"brain lesions","score":0.6230000257492065},{"id":"https://openalex.org/keywords/cerebrospinal-fluid-signal-intensity","display_name":"cerebrospinal fluid signal intensity","score":0.7269999980926514},{"id":"https://openalex.org/keywords/diagnostic-sensitivity","display_name":"diagnostic sensitivity","score":0.4230000078678131}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9410245418548584},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.7165540456771851},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.599596381187439},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.5298561453819275},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.47626635432243347},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3276689648628235},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.15052974224090576},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07253119349479675},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2214/ajr.143.5.1015","doi":"https://doi.org/10.2214/ajr.143.5.1015","is_oa":false,"landing_page_url":"https://doi.org/10.2214/ajr.143.5.1015","pdf_url":null,"source":{"id":"https://openalex.org/S161085503","display_name":"American Journal of Roentgenology","issn_l":"0002-9580","issn":["0002-9580","0361-803X","1546-3141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315781","host_organization_name":"American Roentgen Ray Society","host_organization_lineage":["https://openalex.org/P4310315781"],"host_organization_lineage_names":["American Roentgen Ray Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Roentgenology","raw_type":"journal-article"},{"id":"pmid:6333143","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6333143","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJR. American journal of roentgenology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2063059050","https://openalex.org/W2417175602","https://openalex.org/W2299959830","https://openalex.org/W1972153555","https://openalex.org/W3190513696","https://openalex.org/W2415468308","https://openalex.org/W3096741266","https://openalex.org/W2343858431","https://openalex.org/W1968473274","https://openalex.org/W2993508860"],"abstract_inverted_index":{"Forty-two":[0],"patients":[1],"with":[2,43,98,144],"the":[3,30,81,99,112,129,138],"clinical":[4],"diagnosis":[5],"of":[6,29,32,63,141],"multiple":[7],"sclerosis":[8],"were":[9,37,72,86,95,108],"examined":[10],"by":[11,75],"proton":[12],"magnetic":[13],"resonance":[14],"imaging":[15],"(MRI)":[16],"at":[17],"0.5":[18],"T.":[19],"An":[20],"extensive":[21,89],"protocol":[22],"was":[23,58],"used":[24],"to":[25,120,125],"facilitate":[26],"a":[27],"comparison":[28],"efficacy":[31],"different":[33],"pulse":[34,146],"techniques.":[35],"Results":[36],"also":[38],"compared":[39],"in":[40,53,60,78],"39":[41],"cases":[42],"high-resolution":[44],"x-ray":[45],"computed":[46],"tomography":[47],"(CT).":[48],"MRI":[49,85],"revealed":[50],"characteristic":[51],"abnormalities":[52,82,94],"each":[54],"case,":[55],"whereas":[56],"CT":[57],"positive":[59],"only":[61],"15":[62],"33":[64],"patients.":[65],"Milder":[66],"grades":[67],"1":[68],"and":[69,77,123,133],"2":[70],"disease":[71],"usually":[73],"undetected":[74],"CT,":[76],"all":[79],"cases,":[80],"noted":[83],"on":[84,91,111],"much":[87],"more":[88],"than":[90],"CT.":[92],"Cerebral":[93],"best":[96,109],"shown":[97],"T2-weighted":[100],"spin-echo":[101],"sequence":[102,114],"(TE/TR":[103],"=":[104,116],"120/1000);":[105],"brainstem":[106],"lesions":[107],"defined":[110],"inversion-recovery":[113],"(TE/TI/TR":[115],"30/400/1250).":[117],"Increasing":[118],"TE":[119],"120":[121],"msec":[122,127],"TR":[124],"2000":[126],"heightened":[128],"contrast":[130],"between":[131],"normal":[132],"abnormal":[134],"white":[135],"matter.":[136],"However,":[137],"signal":[139],"intensity":[140],"cerebrospinal":[142],"fluid":[143],"this":[145],"technique":[147],"obscured":[148],"some":[149],"abnormalities.":[150]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}