{"id":"https://openalex.org/W2005160699","doi":"https://doi.org/10.1371/journal.pone.0011879","title":"Screening of In Vivo Activated Genes in Enterococcus faecalis during Insect and Mouse Infections and Growth in Urine","display_name":"Screening of In Vivo Activated Genes in Enterococcus faecalis during Insect and Mouse Infections and Growth in Urine","publication_year":2010,"publication_date":"2010-07-29","ids":{"openalex":"https://openalex.org/W2005160699","doi":"https://doi.org/10.1371/journal.pone.0011879","mag":"2005160699","pmid":"https://pubmed.ncbi.nlm.nih.gov/20686694","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2912369"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0011879","doi":"https://doi.org/10.1371/journal.pone.0011879","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0011879","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011879&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011879&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061831419","display_name":"Aur\u00e9lie Hanin","orcid":"https://orcid.org/0000-0003-4469-537X","observed_orcids":["https://orcid.org/0000-0003-4469-537X"]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aurelie Hanin","raw_affiliation_strings":["Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I98702875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066332691","display_name":"Irina G. Sava","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Irina Sava","raw_affiliation_strings":["Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":null,"display_name":"YinYin Bao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"YinYin Bao","raw_affiliation_strings":["Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025380845","display_name":"Johannes H\u00fcebner","orcid":"https://orcid.org/0000-0003-1232-4646","observed_orcids":["https://orcid.org/0000-0003-1232-4646"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johannes Huebner","raw_affiliation_strings":["Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infection Diseases, Department of Medicine, University Medical Center, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047541127","display_name":"Axel Hartke","orcid":"https://orcid.org/0000-0002-2537-0062","observed_orcids":["https://orcid.org/0000-0002-2537-0062"]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Axel Hartke","raw_affiliation_strings":["Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I98702875"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046141114","display_name":"Yanick Auffray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yanick Auffray","raw_affiliation_strings":["Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I98702875"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033663389","display_name":"Nicolas Sauvageot","orcid":"https://orcid.org/0000-0002-7595-4330","observed_orcids":["https://orcid.org/0000-0002-7595-4330"]},"institutions":[{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I98702875","display_name":"Universit\u00e9 de Caen Normandie","ror":"https://ror.org/051kpcy16","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210105918","https://openalex.org/I98702875"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Nicolas Sauvageot","raw_affiliation_strings":["Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Microbiologie de l'Environnement, EA956 USC INRA2017, Universit\u00e9 de Caen, Caen, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I98702875"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5033663389"],"corresponding_institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I98702875"],"apc_list":{"value":2382,"currency":"USD","value_usd":2382},"apc_paid":{"value":2382,"currency":"USD","value_usd":2382},"fwci":2.2233,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.88292599,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"5","issue":"7","first_page":"e11879","last_page":"e11879"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.6166999936103821,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.6166999936103821,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.350600004196167,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enterococcus-faecalis","display_name":"Enterococcus faecalis","score":1.0},{"id":"https://openalex.org/keywords/in-vivo-gene-expression","display_name":"in vivo gene expression","score":0.5770000219345093},{"id":"https://openalex.org/keywords/galleria-mellonella","display_name":"Galleria mellonella","score":0.7979999780654907},{"id":"https://openalex.org/keywords/peritonitis","display_name":"peritonitis","score":0.8379999995231628},{"id":"https://openalex.org/keywords/commensal-to-pathogen-transition","display_name":"commensal to pathogen transition","score":0.8320000171661377},{"id":"https://openalex.org/keywords/two-component-systems","display_name":"two-component systems","score":0.9890000224113464},{"id":"https://openalex.org/keywords/ankyrin","display_name":"ankyrin","score":0.6579999923706055},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.75},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C2779895986","wikidata":"https://www.wikidata.org/wiki/Q140014","display_name":"Enterococcus faecalis","level":4,"score":0.9008182287216187},{"id":"https://openalex.org/C2779032433","wikidata":"https://www.wikidata.org/wiki/Q761648","display_name":"Galleria mellonella","level":4,"score":0.7999566793441772},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7415428161621094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7202787399291992},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.7007078528404236},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.45170462131500244},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.44715213775634766},{"id":"https://openalex.org/C203075996","wikidata":"https://www.wikidata.org/wiki/Q139677","display_name":"Operon","level":4,"score":0.4181838035583496},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4044302701950073},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17044073343276978},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.12790855765342712}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013293","descriptor_name":"Enterococcus faecalis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013293","descriptor_name":"Enterococcus faecalis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014556","descriptor_name":"Urine","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015964","descriptor_name":"Gene Expression Regulation, Bacterial","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1371/journal.pone.0011879","doi":"https://doi.org/10.1371/journal.pone.0011879","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0011879","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011879&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},{"id":"pmid:20686694","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20686694","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2912369","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2912369/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.354.521","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.521","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/a5/a7/PLoS_One_2010_Jul_29_5(7)_e11879.tar.gz","raw_type":"text"},{"id":"pmh:oai:HAL:hal-02180953v1","doi":null,"is_oa":false,"landing_page_url":"https://normandie-univ.hal.science/hal-02180953","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, 2010, 5 (7), pp.e11879. ⟨10.1371/journal.pone.0011879⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-05347180v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05347180","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, 2010, 5 (7), pp.e11879. ⟨10.1371/journal.pone.0011879⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:b59b6f386e68442398724add34bcb790","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b59b6f386e68442398724add34bcb790","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 5, Iss 7, p e11879 (2010)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/142424","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/Screening_of_In_Vivo_Activated_Genes_in_Enterococcus_faecalis_during_Insect_and_Mouse_Infections_and_Growth_in_Urine/142424","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0011879","doi":"https://doi.org/10.1371/journal.pone.0011879","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pone.0011879","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011879&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005160699.pdf","grobid_xml":"https://content.openalex.org/works/W2005160699.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W1860199759","https://openalex.org/W1901904957","https://openalex.org/W1943327251","https://openalex.org/W1973069935","https://openalex.org/W1978163337","https://openalex.org/W1981777358","https://openalex.org/W1985725647","https://openalex.org/W1990306704","https://openalex.org/W1994475681","https://openalex.org/W1998633553","https://openalex.org/W2003204260","https://openalex.org/W2003707624","https://openalex.org/W2019410656","https://openalex.org/W2020978794","https://openalex.org/W2026330028","https://openalex.org/W2028403456","https://openalex.org/W2039048807","https://openalex.org/W2048483633","https://openalex.org/W2049944840","https://openalex.org/W2051181165","https://openalex.org/W2054763963","https://openalex.org/W2055326033","https://openalex.org/W2059163900","https://openalex.org/W2061181988","https://openalex.org/W2072761181","https://openalex.org/W2078811516","https://openalex.org/W2082088410","https://openalex.org/W2085972597","https://openalex.org/W2096039834","https://openalex.org/W2097804984","https://openalex.org/W2098093769","https://openalex.org/W2102172950","https://openalex.org/W2103682680","https://openalex.org/W2109276669","https://openalex.org/W2109310735","https://openalex.org/W2109847239","https://openalex.org/W2118181458","https://openalex.org/W2118242179","https://openalex.org/W2126687190","https://openalex.org/W2127520891","https://openalex.org/W2128658507","https://openalex.org/W2131948067","https://openalex.org/W2132736261","https://openalex.org/W2134005894","https://openalex.org/W2137515140","https://openalex.org/W2139325759","https://openalex.org/W2141409425","https://openalex.org/W2146193543","https://openalex.org/W2152845055","https://openalex.org/W2154515245","https://openalex.org/W2156960740","https://openalex.org/W2159435025","https://openalex.org/W2161214679","https://openalex.org/W2164248975","https://openalex.org/W2170856048","https://openalex.org/W2170975445","https://openalex.org/W6996356457"],"related_works":["https://openalex.org/W7066551896","https://openalex.org/W196883183","https://openalex.org/W7100256153","https://openalex.org/W2003080181","https://openalex.org/W2025199218","https://openalex.org/W7149537684","https://openalex.org/W2103008742","https://openalex.org/W1781996060","https://openalex.org/W7097755873","https://openalex.org/W4392515758"],"abstract_inverted_index":{"Enterococcus":[0],"faecalis":[1,24,73,143,175,188],"is":[2,14],"part":[3],"of":[4,8,31,41,65,106,129,185,198],"the":[5,15,39,80,104,114,124,141,183],"commensal":[6,44],"microbiota":[7],"humans":[9],"and":[10,77,93,153,161,195],"its":[11],"main":[12],"habitat":[13],"gastrointestinal":[16],"tract.":[17],"Although":[18],"harmless":[19,43],"in":[20,70,79,87,89,94,108,123,146,151,173,191,192],"healthy":[21],"individuals,":[22],"E.":[23,57,72,142,174,187],"has":[25,156,163],"emerged":[26],"as":[27],"a":[28,42,46,51,71,90,95],"major":[29],"cause":[30],"nosocomial":[32],"infections.":[33],"In":[34,53],"order":[35],"to":[36,103,119,140,182],"better":[37],"understand":[38],"transformation":[40],"into":[45],"life-threatening":[47],"pathogen,":[48],"we":[49],"developed":[50],"Recombination-based":[52],"VivoExpression":[54],"Technology":[55],"for":[56],"faecalis.":[58],"Two":[59],"R-IVET":[60,179],"systems":[61],"with":[62],"different":[63],"levels":[64],"sensitivity":[66],"have":[67],"been":[68,158,164],"constructed":[69],"V583":[74],"derivative":[75],"strain":[76],"tested":[78],"insect":[81,125,152],"model":[82],"Galleria":[83],"mellonella,":[84],"during":[85],"growth":[86],"urine,":[88],"mouse":[91,96],"bacteremia":[92],"peritonitis":[97],"model.":[98,127],"Our":[99],"combined":[100],"results":[101],"led":[102,181],"identification":[105,184],"81":[107],"vivo":[109,193],"activated":[110],"genes.":[111],"Among":[112],"them,":[113],"ef_3196/7":[115],"operon":[116],"was":[117,138,170],"shown":[118],"be":[120],"strongly":[121],"induced":[122,150],"host":[126],"Deletion":[128],"this":[130,135,167,199],"operonic":[131],"structure":[132],"demonstrated":[133,165],"that":[134,166],"two-component":[136],"system":[137],"essential":[139],"pathogenic":[144,196],"potential":[145,197],"Galleria.":[147],"Gene":[148],"ef_0377,":[149],"mammalian":[154],"models,":[155],"also":[157,171],"further":[159],"analyzed":[160],"it":[162],"ankyrin-encoding":[168],"gene":[169],"involved":[172],"virulence.":[176],"Thus":[177],"these":[178],"screenings":[180],"new":[186],"factors":[189],"implied":[190],"persistence":[194],"opportunistic":[200],"pathogen.":[201]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}