{"id":"https://openalex.org/W2005124365","doi":"https://doi.org/10.4088/jcp.10m06176blu","title":"Comorbidity Patterns of Anxiety and Depressive Disorders in a Large Cohort Study","display_name":"Comorbidity Patterns of Anxiety and Depressive Disorders in a Large Cohort Study","publication_year":2011,"publication_date":"2011-01-24","ids":{"openalex":"https://openalex.org/W2005124365","doi":"https://doi.org/10.4088/jcp.10m06176blu","mag":"2005124365","pmid":"https://pubmed.ncbi.nlm.nih.gov/21294994"},"language":"en","primary_location":{"id":"doi:10.4088/jcp.10m06176blu","doi":"https://doi.org/10.4088/jcp.10m06176blu","is_oa":false,"landing_page_url":"https://doi.org/10.4088/jcp.10m06176blu","pdf_url":null,"source":{"id":"https://openalex.org/S17992710","display_name":"The Journal of Clinical Psychiatry","issn_l":"0160-6689","issn":["0160-6689","1534-8628","1555-2101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077808650","display_name":"Femke Lamers","orcid":"https://orcid.org/0000-0003-4344-5766","observed_orcids":["https://orcid.org/0000-0003-4344-5766"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Femke Lamers","raw_affiliation_strings":["Department of Psychiatry/EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands. f.lamers@vumc.nl","Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry/EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands. f.lamers@vumc.nl","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I911458345"]},{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080407285","display_name":"Patricia van Oppen","orcid":"https://orcid.org/0000-0002-9509-629X","observed_orcids":["https://orcid.org/0000-0002-9509-629X"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Patricia van Oppen","raw_affiliation_strings":["Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013982476","display_name":"Hannie C. Comijs","orcid":"https://orcid.org/0000-0001-6693-7363","observed_orcids":["https://orcid.org/0000-0001-6693-7363"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hannie C. Comijs","raw_affiliation_strings":["Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003786607","display_name":"Johannes H. Smit","orcid":"https://orcid.org/0000-0002-2062-8378","observed_orcids":["https://orcid.org/0000-0002-2062-8378","https://orcid.org/0000-0002-6070-4865"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Johannes H. Smit","raw_affiliation_strings":["Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059840812","display_name":"Philip Spinhoven","orcid":"https://orcid.org/0000-0002-4117-335X","observed_orcids":["https://orcid.org/0000-0002-4117-335X"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Philip Spinhoven","raw_affiliation_strings":["Leiden Univ, Leiden University, Inst Psychol"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leiden Univ, Leiden University, Inst Psychol","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045274254","display_name":"Anton J.L.M. van Balkom","orcid":"https://orcid.org/0000-0001-9171-0208","observed_orcids":["https://orcid.org/0000-0001-9171-0208"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anton J. L. M. van Balkom","raw_affiliation_strings":["Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090875089","display_name":"Willem A. Nolen","orcid":"https://orcid.org/0000-0002-2092-9891","observed_orcids":["https://orcid.org/0000-0002-2092-9891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Willem A. Nolen","raw_affiliation_strings":["Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032227732","display_name":"Frans G. Zitman","orcid":"https://orcid.org/0000-0003-1987-988X","observed_orcids":["https://orcid.org/0000-0003-1987-988X"]},"institutions":[{"id":"https://openalex.org/I121797337","display_name":"Leiden University","ror":"https://ror.org/027bh9e22","country_code":"NL","type":"education","lineage":["https://openalex.org/I121797337"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Frans G. Zitman","raw_affiliation_strings":["Leiden Univ, Leiden University, Dept Psychiat, Med Ctr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Leiden Univ, Leiden University, Dept Psychiat, Med Ctr","institution_ids":["https://openalex.org/I121797337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081531461","display_name":"Aartjan T.F. Beekman","orcid":"https://orcid.org/0000-0003-2382-1410","observed_orcids":["https://orcid.org/0000-0003-2382-1410"]},"institutions":[{"id":"https://openalex.org/I4210124285","display_name":"Amsterdam Public Health","ror":"https://ror.org/0258apj61","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210124285"]},{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Aartjan T. F. Beekman","raw_affiliation_strings":["Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Univ Amsterdam, VU University Amsterdam, Dept Psychiat, Med Ctr, EMGO Inst Hlth & Care Res","institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055183685","display_name":"Brenda W.J.H. Penninx","orcid":"https://orcid.org/0000-0001-7779-9672","observed_orcids":["https://orcid.org/0000-0001-7779-9672"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brenda W. J. H. Penninx","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5077808650"],"corresponding_institution_ids":["https://openalex.org/I4210124285","https://openalex.org/I865915315","https://openalex.org/I911458345"],"apc_list":null,"apc_paid":null,"fwci":27.5353,"has_fulltext":false,"cited_by_count":913,"citation_normalized_percentile":{"value":0.99730474,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"72","issue":"03","first_page":"341","last_page":"348"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.6182000041007996,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.6182000041007996,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10272","display_name":"Mental Health Treatment and Access","score":0.2816999852657318,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.040800001472234726,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anxiety-disorders","display_name":"anxiety disorders","score":0.9980000257492065},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.9200000166893005},{"id":"https://openalex.org/keywords/childhood-trauma","display_name":"childhood trauma","score":0.9020000100135803},{"id":"https://openalex.org/keywords/neuroticism","display_name":"neuroticism","score":0.9950000047683716},{"id":"https://openalex.org/keywords/age-of-onset","display_name":"age of onset","score":0.890999972820282},{"id":"https://openalex.org/keywords/symptom-duration","display_name":"symptom duration","score":0.9539999961853027},{"id":"https://openalex.org/keywords/symptom-severity","display_name":"symptom severity","score":0.9769999980926514},{"id":"https://openalex.org/keywords/chronicity","display_name":"chronicity","score":0.7300000190734863},{"id":"https://openalex.org/keywords/netherlands-study-of-depression-and-anxiety","display_name":"NESDA","score":0.8489999771118164},{"id":"https://openalex.org/keywords/dsm-iv-tr-criteria","display_name":"DSM-IV-TR diagnostic criteria","score":0.7590000033378601},{"id":"https://openalex.org/keywords/vulnerability-factors","display_name":"vulnerability factors","score":0.4909999966621399},{"id":"https://openalex.org/keywords/risk-factors-for-depression","display_name":"risk factors for depression","score":0.4230000078678131}],"concepts":[{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.9189337491989136},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.7928997874259949},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.6203431487083435},{"id":"https://openalex.org/C2776317618","wikidata":"https://www.wikidata.org/wiki/Q544006","display_name":"Anxiety disorder","level":3,"score":0.5847853422164917},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5777596831321716},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4658281207084656},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.45209696888923645},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3932776153087616},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.368928462266922},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.05287006497383118},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D001008","descriptor_name":"Anxiety Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010555","descriptor_name":"Personality Inventory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":12,"locations":[{"id":"doi:10.4088/jcp.10m06176blu","doi":"https://doi.org/10.4088/jcp.10m06176blu","is_oa":false,"landing_page_url":"https://doi.org/10.4088/jcp.10m06176blu","pdf_url":null,"source":{"id":"https://openalex.org/S17992710","display_name":"The Journal of Clinical Psychiatry","issn_l":"0160-6689","issn":["0160-6689","1534-8628","1555-2101"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Clinical Psychiatry","raw_type":"journal-article"},{"id":"pmid:21294994","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21294994","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/32b6b5c0-5479-4ae9-93ff-dcc41f6018ad","doi":null,"is_oa":false,"landing_page_url":"https://research.vumc.nl/en/publications/32b6b5c0-5479-4ae9-93ff-dcc41f6018ad","pdf_url":null,"source":{"id":"https://openalex.org/S7407055350","display_name":"Amsterdam UMC (VU Amsterdam) - Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lamers, F, van Oppen, P C, Comijs, H C, Smit, J H, Spinhoven, P, van Balkom, A J L M, Nolen, W A, Zitman, F G, Beekman, A T F & Penninx, B W J H 2011, 'Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)', Journal of Clinical Psychiatry, vol. 72, no. 3, pp. 341-348. https://doi.org/10.4088/JCP.10m06176blu","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:lumc:oai:scholarlypublications.universiteitleiden.nl:item_3013809","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1887/118231","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"VOLUME=72;ISSUE=3;STARTPAGE=341;ENDPAGE=348;TITLE=None","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:alma.31UKB_LEU:9940753587902711","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1887/118231","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/110a95e1-28b8-417a-9e84-9088b95becbd","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/110a95e1-28b8-417a-9e84-9088b95becbd","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lamers, F, van Oppen, P C, Comijs, H C, Smit, J H, Spinhoven, P, van Balkom, A J L M, Nolen, W A, Zitman, F G, Beekman, A T F & Penninx, B W J H 2011, 'Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)', Journal of clinical psychiatry, vol. 72, no. 3, pp. 341-348. https://doi.org/10.4088/JCP.10m06176blu","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.rug.nl:openaire_cris_publications/2f49130b-680f-423d-bfb2-e365808109b1","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11370/2f49130b-680f-423d-bfb2-e365808109b1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lamers, F, van Oppen, P, Comijs, H C, Smit, J H, Spinhoven, P, van Balkom, A J L M, Nolen, W A, Zitman, F G, Beekman, A T F & Penninx, B 2011, 'Comorbidity Patterns of Anxiety and Depressive Disorders in a Large Cohort Study : The Netherlands Study of Depression and Anxiety (NESDA)', Journal of Clinical Psychiatry, vol. 72, no. 3, pp. 341-348. https://doi.org/10.4088/JCP.10m06176blu","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:research.vu.nl:openaire_cris_publications/5f6cfa3a-590e-4a2a-a6b4-8f49126bb941","doi":null,"is_oa":false,"landing_page_url":"https://research.vu.nl/en/publications/5f6cfa3a-590e-4a2a-a6b4-8f49126bb941","pdf_url":null,"source":{"id":"https://openalex.org/S4306401107","display_name":"VU Research Portal","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I865915315","host_organization_name":"Vrije Universiteit Amsterdam","host_organization_lineage":["https://openalex.org/I865915315"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lamers, F, van Oppen, P C, Comijs, H C, Smit, J H, Spinhoven, P, van Balkom, A J L M, Nolen, W A, Zitman, F G, Beekman, A T F & Penninx, B W J H 2011, 'Comorbidity patterns of anxiety and depressive disorders in a large cohort study: the Netherlands Study of Depression and Anxiety (NESDA)', Journal of Clinical Psychiatry, vol. 72, no. 3, pp. 341-348. https://doi.org/10.4088/JCP.10m06176blu","raw_type":"article"},{"id":"pmh:oai:scholarlypublications.universiteitleiden.nl:item_3013809","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1887/118231","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:rug:oai:pure.rug.nl:publications/2f49130b-680f-423d-bfb2-e365808109b1","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/2f49130b-680f-423d-bfb2-e365808109b1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Psychiatry, 72(3), 341 - 348. Physicians Postgraduate Press Inc.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vu:oai:research.vu.nl:publications/5f6cfa3a-590e-4a2a-a6b4-8f49126bb941","doi":null,"is_oa":false,"landing_page_url":"https://research.vu.nl/en/publications/5f6cfa3a-590e-4a2a-a6b4-8f49126bb941","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Psychiatry, 72(3), 341 - 348. AIP Press","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/32b6b5c0-5479-4ae9-93ff-dcc41f6018ad","doi":null,"is_oa":false,"landing_page_url":"https://research.vumc.nl/en/publications/32b6b5c0-5479-4ae9-93ff-dcc41f6018ad","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Clinical Psychiatry, 72(3), 341 - 348. Physicians Postgraduate Press Inc.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6899999976158142,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2964000526","https://openalex.org/W2378173657","https://openalex.org/W2019864473","https://openalex.org/W2040883278","https://openalex.org/W4299915278","https://openalex.org/W2105517360","https://openalex.org/W2088478022","https://openalex.org/W1988050647","https://openalex.org/W2079488088","https://openalex.org/W4284886562"],"abstract_inverted_index":{"BACKGROUND:":[0],"Comorbidity":[1,20,144,225,274],"of":[2,18,41,60,64,92,103,145,174,185,213,239,241,295,323],"depressive":[3,24,43,83,112,142,146,186,242,279],"and":[4,9,25,38,44,66,72,78,84,97,100,118,137,147,196,219,263,278,318,321],"anxiety":[5,26,45,85,124,131,148,188,216,232,244,277],"disorders":[6,27,46,86,104,149,280,292],"is":[7,287,302],"common":[8],"has":[10],"been":[11,30],"shown":[12],"to":[13,204,230,289],"be":[14],"a":[15,50,111,116,121,129,135,140,236,309],"consistent":[16],"predictor":[17],"chronicity.":[19],"patterns":[21,37],"among":[22],"specific":[23,310],"have":[28],"not":[29],"extensively":[31],"reported.":[32],"This":[33,301],"study":[34],"examines":[35],"comorbidity":[36,80,93],"temporal":[39,101],"sequencing":[40,102],"separate":[42],"using":[47],"data":[48,56],"from":[49,202],"large":[51],"psychiatric":[52],"cohort.":[53],"METHOD:":[54],"Baseline":[55],"(N":[57],"=":[58,157,165,178,191,247,258,268],"1,783)":[59],"the":[61,296],"Netherlands":[62],"Study":[63],"Depression":[65],"Anxiety,":[67],"collected":[68],"between":[69],"September":[70],"2004":[71],"February":[73],"2007,":[74],"were":[75,89,105,281],"used.":[76],"Current":[77],"lifetime":[79,122,141],"rates":[81,275],"for":[82,299],"(DSM-IV-TR":[87],"criteria)":[88],"calculated.":[90],"Associations":[91],"with":[94,110,128,152,226,235,313],"sociodemographic,":[95],"vulnerability,":[96],"clinical":[98],"characteristics,":[99],"examined.":[106],"RESULTS:":[107],"Of":[108,126],"those":[109],"disorder,":[113,132],"67%":[114],"had":[115,120,134,139],"current":[117,130,136],"75%":[119],"comorbid":[123,214,306],"disorder.":[125,143],"persons":[127],"63%":[133],"81%":[138],"was":[150,233],"associated":[151,234],"more":[153,314],"childhood":[154,315],"trauma":[155],"(OR":[156,164,177,190,246,257,267],"1.19;":[158],"95%":[159,167,180,193,249,260,270],"CI,":[160,168,181,194,250,261,271],"1.06-1.33),":[161],"higher":[162,197,319],"neuroticism":[163],"1.05;":[166],"1.02-1.08),":[169],"earlier":[170,252],"age":[171,253],"at":[172,254],"onset":[173,256],"first":[175,255],"disorder":[176],"1.59;":[179],"1.22-2.07),":[182],"longer":[183],"duration":[184,238,322],"and/or":[187,243],"symptoms":[189,240,245,266],"1.01;":[192],"1.01-1.01),":[195],"symptom":[198],"severity":[199,320],"(ORs":[200],"ranging":[201],"1.01":[203],"1.03;":[205],"all":[206],"P":[207],"values":[208],"<":[209],".05).":[210],"In":[211],"57%":[212],"cases,":[215],"preceded":[217,223],"depression,":[218],"in":[220,276],"18%,":[221],"depression":[222,228],"anxiety.":[224],"preceding":[227,231],"compared":[229],"shorter":[237],"0.99;":[248],"0.98-0.99),":[251],"0.46;":[259],"0.31-0.68),":[262],"fewer":[264],"fear":[265],"0.98;":[269],"0.97-0.99).":[272],"CONCLUSIONS:":[273],"very":[282],"high,":[283],"indicating":[284],"that":[285],"it":[286],"advisable":[288],"assess":[290],"both":[291],"routinely":[293],"regardless":[294],"primary":[297],"reason":[298],"consultation.":[300],"especially":[303],"important":[304],"since":[305],"patients":[307],"showed":[308],"vulnerability":[311],"pattern,":[312],"trauma,":[316],"neuroticism,":[317],"symptoms.":[324]},"counts_by_year":[{"year":2026,"cited_by_count":72},{"year":2025,"cited_by_count":85},{"year":2024,"cited_by_count":93},{"year":2023,"cited_by_count":89},{"year":2022,"cited_by_count":112},{"year":2021,"cited_by_count":104},{"year":2020,"cited_by_count":72},{"year":2019,"cited_by_count":36},{"year":2018,"cited_by_count":66},{"year":2017,"cited_by_count":42},{"year":2016,"cited_by_count":43},{"year":2015,"cited_by_count":28},{"year":2014,"cited_by_count":26},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":13}],"updated_date":"2026-10-22T09:42:04.148104","created_date":"2016-06-24T00:00:00"}