{"id":"https://openalex.org/W2005106983","doi":"https://doi.org/10.1590/s1516-44462009005000015","title":"Effects of fluoxetine and imipramine in rat fetuses treated during a critical gestational period: a macro and microscopic study","display_name":"Effects of fluoxetine and imipramine in rat fetuses treated during a critical gestational period: a macro and microscopic study","publication_year":2009,"publication_date":"2009-12-18","ids":{"openalex":"https://openalex.org/W2005106983","doi":"https://doi.org/10.1590/s1516-44462009005000015","mag":"2005106983","pmid":"https://pubmed.ncbi.nlm.nih.gov/20027488"},"language":"en","primary_location":{"id":"doi:10.1590/s1516-44462009005000015","doi":"https://doi.org/10.1590/s1516-44462009005000015","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1516-44462009005000015","pdf_url":"https://www.scielo.br/j/rbp/a/9Q4FV9B33YqYy8RWtbf8rkC/?lang=en&format=pdf","source":{"id":"https://openalex.org/S71457257","display_name":"Brazilian Journal of Psychiatry","issn_l":"1516-4446","issn":["1516-4446","1809-452X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310312528","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Psiquiatria","host_organization_lineage":["https://openalex.org/P4310312528"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Psiquiatria"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Psiquiatria","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.scielo.br/j/rbp/a/9Q4FV9B33YqYy8RWtbf8rkC/?lang=en&format=pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070951922","display_name":"C\u00e1tia Aline Silva Swerts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143202","display_name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano","ror":"https://ror.org/04abxn418","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210143202"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"C\u00e1tia Aline Silva Swerts","raw_affiliation_strings":["Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil","institution_ids":["https://openalex.org/I4210143202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110914115","display_name":"Ana Maria Duarte Dias Costa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143202","display_name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano","ror":"https://ror.org/04abxn418","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210143202"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana Maria Duarte Dias Costa","raw_affiliation_strings":["Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil","institution_ids":["https://openalex.org/I4210143202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069730758","display_name":"Alessandra Esteves","orcid":"https://orcid.org/0000-0002-0228-2940","observed_orcids":["https://orcid.org/0000-0002-0228-2940"]},"institutions":[{"id":"https://openalex.org/I23925101","display_name":"Universidade Federal de Alfenas","ror":"https://ror.org/034vpja60","country_code":"BR","type":"education","lineage":["https://openalex.org/I23925101"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alessandra Esteves","raw_affiliation_strings":["Universidade Federal de Alfenas, Brazil","Universidade Federal de Alfenas, Alfenas, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Federal de Alfenas, Brazil","institution_ids":["https://openalex.org/I23925101"]},{"raw_affiliation_string":"Universidade Federal de Alfenas, Alfenas, Brazil","institution_ids":["https://openalex.org/I23925101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068251273","display_name":"Carla Elaine Silva Borato","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143202","display_name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano","ror":"https://ror.org/04abxn418","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210143202"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carla Elaine Silva Borato","raw_affiliation_strings":["Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil","institution_ids":["https://openalex.org/I4210143202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036550619","display_name":"M\u00e1rio S\u00e9rgio Oliveira Swerts","orcid":"https://orcid.org/0000-0003-1867-7880","observed_orcids":["https://orcid.org/0000-0003-1867-7880"]},"institutions":[{"id":"https://openalex.org/I4210143202","display_name":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano","ror":"https://ror.org/04abxn418","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210143202"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"M\u00e1rio S\u00e9rgio Oliveira Swerts","raw_affiliation_strings":["Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidade Jos\u00e9 do Ros\u00e1rio Vellano, Brazil","institution_ids":["https://openalex.org/I4210143202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2374,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.80245174,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"32","issue":"2","first_page":"152","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.6118000149726868,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11633","display_name":"Prenatal Substance Exposure Effects","score":0.6118000149726868,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.2190999984741211,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.13349999487400055,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluoxetine","display_name":"fluoxetine","score":0.996999979019165},{"id":"https://openalex.org/keywords/imipramine","display_name":"imipramine","score":1.0},{"id":"https://openalex.org/keywords/antidepressants","display_name":"antidepressants","score":0.628000020980835},{"id":"https://openalex.org/keywords/prenatal-drug-exposure","display_name":"prenatal drug exposure","score":0.7889999747276306},{"id":"https://openalex.org/keywords/fetal-development","display_name":"fetal development","score":0.6859999895095825},{"id":"https://openalex.org/keywords/placental-weight","display_name":"placental weight","score":0.8230000138282776},{"id":"https://openalex.org/keywords/fetal-brain-weight","display_name":"fetal brain weight","score":0.9010000228881836},{"id":"https://openalex.org/keywords/neuronal-count","display_name":"neuronal count","score":0.503000020980835},{"id":"https://openalex.org/keywords/maternal-antidepressant-use","display_name":"maternal antidepressant use","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.8354489207267761},{"id":"https://openalex.org/C2776134451","wikidata":"https://www.wikidata.org/wiki/Q422244","display_name":"Fluoxetine","level":4,"score":0.75470370054245},{"id":"https://openalex.org/C2779145073","wikidata":"https://www.wikidata.org/wiki/Q58396","display_name":"Imipramine","level":3,"score":0.695357620716095},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.6164601445198059},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6013160347938538},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5031489729881287},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.49211591482162476},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.4913868010044098},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4500008225440979},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.43995600938796997},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.4201255738735199},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39585036039352417},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.275290310382843},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13530904054641724},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.09053424000740051},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005473","descriptor_name":"Fluoxetine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007099","descriptor_name":"Imipramine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018765","descriptor_name":"Dopamine Uptake Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D020567","descriptor_name":"Fetal Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1590/s1516-44462009005000015","doi":"https://doi.org/10.1590/s1516-44462009005000015","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1516-44462009005000015","pdf_url":"https://www.scielo.br/j/rbp/a/9Q4FV9B33YqYy8RWtbf8rkC/?lang=en&format=pdf","source":{"id":"https://openalex.org/S71457257","display_name":"Brazilian Journal of Psychiatry","issn_l":"1516-4446","issn":["1516-4446","1809-452X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310312528","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Psiquiatria","host_organization_lineage":["https://openalex.org/P4310312528"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Psiquiatria"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Psiquiatria","raw_type":"journal-article"},{"id":"pmid:20027488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20027488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)","raw_type":"Journal Article"},{"id":"pmh:oai:scielo:S1516-44462010000200010","doi":null,"is_oa":true,"landing_page_url":"http://old.scielo.br/scielo.php?script=sci_arttext&amp;pid=S1516-44462010000200010","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian Journal of Psychiatry v.32 n.2 2010","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2745902","doi":null,"is_oa":true,"landing_page_url":"http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462010000200010","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brazilian Journal of Psychiatry v.32 n.2 2010","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:93e48458fd5743cdaeb53e4c7661e459","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/93e48458fd5743cdaeb53e4c7661e459","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brazilian Journal of Psychiatry, Vol 32, Iss 2, Pp 152-158 (2010)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1590/s1516-44462009005000015","doi":"https://doi.org/10.1590/s1516-44462009005000015","is_oa":true,"landing_page_url":"https://doi.org/10.1590/s1516-44462009005000015","pdf_url":"https://www.scielo.br/j/rbp/a/9Q4FV9B33YqYy8RWtbf8rkC/?lang=en&format=pdf","source":{"id":"https://openalex.org/S71457257","display_name":"Brazilian Journal of Psychiatry","issn_l":"1516-4446","issn":["1516-4446","1809-452X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","scielo","vabb-shw"],"host_organization":"https://openalex.org/P4310312528","host_organization_name":"Associa\u00e7\u00e3o Brasileira de Psiquiatria","host_organization_lineage":["https://openalex.org/P4310312528"],"host_organization_lineage_names":["Associa\u00e7\u00e3o Brasileira de Psiquiatria"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Brasileira de Psiquiatria","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2005106983.pdf","grobid_xml":"https://content.openalex.org/works/W2005106983.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W18348504","https://openalex.org/W165896979","https://openalex.org/W192156036","https://openalex.org/W1534177995","https://openalex.org/W1576939133","https://openalex.org/W1802397543","https://openalex.org/W1894813147","https://openalex.org/W1972980176","https://openalex.org/W1977221292","https://openalex.org/W1979391895","https://openalex.org/W1979423926","https://openalex.org/W1981212202","https://openalex.org/W1988030263","https://openalex.org/W1989830600","https://openalex.org/W2001373350","https://openalex.org/W2003164196","https://openalex.org/W2005110036","https://openalex.org/W2010487484","https://openalex.org/W2017406364","https://openalex.org/W2020407075","https://openalex.org/W2040917199","https://openalex.org/W2049760008","https://openalex.org/W2055997114","https://openalex.org/W2075267318","https://openalex.org/W2084206783","https://openalex.org/W2086907721","https://openalex.org/W2089541107","https://openalex.org/W2091703967","https://openalex.org/W2101143167","https://openalex.org/W2107835998","https://openalex.org/W2116435621","https://openalex.org/W2136107811","https://openalex.org/W2139735674","https://openalex.org/W2154550415","https://openalex.org/W2164579326","https://openalex.org/W2332320054","https://openalex.org/W2403189216","https://openalex.org/W2410516448","https://openalex.org/W2417966821","https://openalex.org/W2464907126","https://openalex.org/W2559961688","https://openalex.org/W3203814282"],"related_works":["https://openalex.org/W2184500259","https://openalex.org/W7096545752","https://openalex.org/W2055997114","https://openalex.org/W3005972374","https://openalex.org/W2189470156","https://openalex.org/W2010043022","https://openalex.org/W1576939133","https://openalex.org/W2024213407","https://openalex.org/W2800299960","https://openalex.org/W3081584802"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"morphological":[3],"alterations":[4,216],"in":[5,180,185,191,212,217],"rat":[6],"fetuses":[7,80,213],"treated":[8,32],"with":[9,33],"fluoxetine":[10],"and":[11,31,43,71,84,88,103,124,138,170,188],"imipramine":[12,51],"during":[13],"the":[14,40,65,92,106,129,154,159,192,202],"\"critical\"":[15],"period":[16],"of":[17,36,46,91,162,178,194,204],"gestation.":[18],"METHOD:":[19],"Fifteen":[20],"female":[21],"rats":[22,181],"were":[23,61,69,81,95],"separated":[24],"into":[25],"three":[26],"groups":[27],"(n":[28],"=":[29],"5)":[30],"10":[34],"mg/kg/day":[35],"test":[37],"substances":[38],"on":[39],"ninth,":[41],"tenth":[42],"eleventh":[44],"day":[45,57],"pregnancy:":[47],"G1,":[48],"fluoxetine;":[49],"G2,":[50],"hydrochloride;":[52],"G3":[53,136,157],"(control),":[54],"saline.":[55],"On":[56],"21,":[58],"cesarean":[59],"sections":[60],"performed":[62],"to":[63,168,215],"release":[64],"fetuses,":[66],"whose":[67],"bodies":[68],"weighed":[70,120],"macroscopically":[72],"analyzed.":[73],"The":[74,79,176],"placenta":[75],"was":[76],"also":[77],"weighed.":[78,89],"then":[82],"fixed":[83],"their":[85,218],"encephala":[86],"removed":[87],"Sections":[90],"frontal":[93,196],"lobe":[94,197],"taken":[96],"for":[97],"histological":[98],"neuron":[99],"counting.":[100],"RESULTS:":[101],"G1":[102,119,140,145,169],"G2":[104,123,127,171],"showed":[105,113,158],"highest":[107,130,160],"fetal":[108,186,195],"body":[109],"weight.":[110],"Placental":[111],"weight":[112,187],"statistical":[114],"differences":[115],"(p":[116,141,149,172],"<":[117,142,173],"0.01):":[118],"more":[121],"than":[122],"G3.":[125],"Otherwise,":[126],"exhibited":[128],"encephalon":[131],"weight,":[132],"statistically":[133,148],"differing":[134],"from":[135,153],"(control)":[137],"fluoxetine-treated":[139],"0.01).":[143,174],"However,":[144],"did":[146],"not":[147],">":[150],"0.01)":[151],"differ":[152],"control":[155],"group.":[156],"number":[161,193],"neurons":[163],"per":[164],"area":[165],"when":[166],"compared":[167],"CONCLUSION:":[175],"use":[177,203],"antidepressants":[179,205],"caused":[182],"an":[183],"increase":[184],"a":[189],"decrease":[190],"neurons,":[198],"thus":[199],"suggesting":[200],"that":[201],"by":[206],"pregnant":[207],"women":[208],"can":[209],"induce":[210],"depression":[211],"due":[214],"neural":[219],"development.":[220]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}