{"id":"https://openalex.org/W2004884830","doi":"https://doi.org/10.1038/sj.bjc.6602246","title":"Characterisation of breast fine-needle aspiration biopsies by centrosome aberrations and genomic instability","display_name":"Characterisation of breast fine-needle aspiration biopsies by centrosome aberrations and genomic instability","publication_year":2004,"publication_date":"2004-11-23","ids":{"openalex":"https://openalex.org/W2004884830","doi":"https://doi.org/10.1038/sj.bjc.6602246","mag":"2004884830","pmid":"https://pubmed.ncbi.nlm.nih.gov/15558069","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2361862"},"language":"en","primary_location":{"id":"doi:10.1038/sj.bjc.6602246","doi":"https://doi.org/10.1038/sj.bjc.6602246","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6602246","pdf_url":"https://www.nature.com/articles/6602246.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/6602246.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081180398","display_name":"Ulrike Kronenwett","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"U Kronenwett","raw_affiliation_strings":["Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, 17176 Stockholm, Sweden. Ulrike.Kronenwett@cck.ki.se","Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, 17176 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, 17176 Stockholm, Sweden. Ulrike.Kronenwett@cck.ki.se","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, 17176 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071667561","display_name":"S\u00f6ren Huwendiek","orcid":"https://orcid.org/0000-0001-6116-9633","observed_orcids":["https://orcid.org/0000-0001-6116-9633"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"S Huwendiek","raw_affiliation_strings":["Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Castro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"J Castro","raw_affiliation_strings":["Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031392514","display_name":"Thomas Ried","orcid":"https://orcid.org/0000-0002-0767-6009","observed_orcids":["https://orcid.org/0000-0002-0767-6009"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210149717","display_name":"Center for Cancer Research","ror":"https://ror.org/05bjen692","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T Ried","raw_affiliation_strings":["Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, 20892-0913, MD, USA","Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, 20892-0913, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]},{"raw_affiliation_string":"Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4210149717"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066704814","display_name":"Gert Auer","orcid":"https://orcid.org/0000-0003-3911-0285","observed_orcids":["https://orcid.org/0000-0003-3911-0285"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"G Auer","raw_affiliation_strings":["Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, 17176, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Oncology and Pathology, Division of Cellular and Molecular Analysis, Cancer Center Karolinska (CCK), R8:04, Karolinska Institute and Hospital, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5081180398"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":{"value":5190,"currency":"USD","value_usd":5190},"fwci":1.0168,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.71120436,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"92","issue":"2","first_page":"389","last_page":"395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.8978999853134155,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.8978999853134155,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.04270000010728836,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.01979999989271164,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/centrosome-aberrations","display_name":"centrosome aberrations","score":0.9599999785423279},{"id":"https://openalex.org/keywords/genomic-instability","display_name":"genomic instability","score":0.984000027179718},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6729999780654907},{"id":"https://openalex.org/keywords/fine-needle-aspiration","display_name":"fine-needle aspiration","score":0.8970000147819519},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.8960000276565552},{"id":"https://openalex.org/keywords/dna-ploidy","display_name":"DNA ploidy","score":0.9829999804496765},{"id":"https://openalex.org/keywords/gamma-tubulin","display_name":"gamma-tubulin","score":0.7879999876022339},{"id":"https://openalex.org/keywords/breast-lesions","display_name":"breast lesions","score":0.4819999933242798},{"id":"https://openalex.org/keywords/dna-image-cytometry","display_name":"DNA image cytometry","score":0.6840000152587891}],"concepts":[{"id":"https://openalex.org/C10447061","wikidata":"https://www.wikidata.org/wiki/Q190769","display_name":"Centrosome","level":4,"score":0.9393255710601807},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.7255717515945435},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6355502605438232},{"id":"https://openalex.org/C178169997","wikidata":"https://www.wikidata.org/wiki/Q2892636","display_name":"Genome instability","level":4,"score":0.553030788898468},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5297953486442566},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.43749117851257324},{"id":"https://openalex.org/C143191323","wikidata":"https://www.wikidata.org/wiki/Q118406","display_name":"Ploidy","level":3,"score":0.4276408553123474},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.34088730812072754},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.29412469267845154},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2083669900894165},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.20425432920455933},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.167229562997818},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.16555899381637573},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.1378110647201538},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11096933484077454},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1095350980758667},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0953775942325592}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000782","descriptor_name":"Aneuploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018385","descriptor_name":"Centrosome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D042822","descriptor_name":"Genomic Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044963","descriptor_name":"Biopsy, Fine-Needle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/sj.bjc.6602246","doi":"https://doi.org/10.1038/sj.bjc.6602246","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6602246","pdf_url":"https://www.nature.com/articles/6602246.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2361862","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2361862","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Cancer","raw_type":"Text"},{"id":"pmid:15558069","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15558069","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/sj.bjc.6602246","doi":"https://doi.org/10.1038/sj.bjc.6602246","is_oa":true,"landing_page_url":"https://doi.org/10.1038/sj.bjc.6602246","pdf_url":"https://www.nature.com/articles/6602246.pdf","source":{"id":"https://openalex.org/S62966998","display_name":"British Journal of Cancer","issn_l":"0007-0920","issn":["0007-0920","1532-1827"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320324250","display_name":"Cancerf\u00f6reningen i Stockholm","ror":"https://ror.org/00m8d6786"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004884830.pdf","grobid_xml":"https://content.openalex.org/works/W2004884830.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W20768369","https://openalex.org/W91956966","https://openalex.org/W145583534","https://openalex.org/W1488637588","https://openalex.org/W1502721583","https://openalex.org/W1635186783","https://openalex.org/W1659503129","https://openalex.org/W1896077678","https://openalex.org/W1967149801","https://openalex.org/W1975778708","https://openalex.org/W1976977538","https://openalex.org/W1983461362","https://openalex.org/W1984642320","https://openalex.org/W1991033145","https://openalex.org/W1998052486","https://openalex.org/W2003886265","https://openalex.org/W2005194686","https://openalex.org/W2018444027","https://openalex.org/W2020544881","https://openalex.org/W2020658023","https://openalex.org/W2032920533","https://openalex.org/W2033306271","https://openalex.org/W2035569367","https://openalex.org/W2065313842","https://openalex.org/W2068121956","https://openalex.org/W2072864944","https://openalex.org/W2073213328","https://openalex.org/W2130394123","https://openalex.org/W2133745628","https://openalex.org/W2140760216","https://openalex.org/W2403115442","https://openalex.org/W2404329934","https://openalex.org/W2417823934","https://openalex.org/W2418222453","https://openalex.org/W4238918209"],"related_works":["https://openalex.org/W2142356167","https://openalex.org/W2025324864","https://openalex.org/W1967149801","https://openalex.org/W2004968303","https://openalex.org/W2130394123","https://openalex.org/W2175382320","https://openalex.org/W1531796755","https://openalex.org/W7099630719","https://openalex.org/W2031261666","https://openalex.org/W3138884706"],"abstract_inverted_index":{"Recent":[0],"studies":[1],"have":[2],"suggested":[3],"that":[4,191],"aneuploidy":[5],"in":[6,36,212],"malignant":[7,173],"tumours":[8,159],"could":[9,71],"be":[10,72],"a":[11,57,112,125],"consequence":[12],"of":[13,41,60,65,83,98,114,119,137,147,179,183,200,209,214],"centrosome":[14,30,51,86,122,150,192],"aberrations.":[15,52],"Using":[16],"immunofluorescence":[17],"analysis":[18,211],"with":[19,62,85,100,121,129,149,167,176,195],"an":[20],"antibody":[21],"against":[22],"gamma-tubulin":[23],"and":[24,32,89,92,135,171,181,198,217,224],"DNA":[25,33,53,102],"image":[26],"cytometry,":[27],"we":[28],"measured":[29],"aberrations":[31,87,123,151,193,220],"ploidy":[34],"patterns":[35],"fine-needle":[37],"aspiration":[38],"biopsies":[39],"(FNABs)":[40],"58":[42],"breast":[43,216],"lesions.":[44],"Benign":[45],"lesions":[46,166],"did":[47],"not":[48],"show":[49],"any":[50],"diploid":[54],"carcinomas":[55,70],"showed":[56],"mean":[58,177],"percentage":[59,82,97,118,146],"cells":[61,84,99,120,148],"centrosomal":[63,169,184,210,219],"defects":[64],"2.1%.":[66],"The":[67,117],"aneuploid":[68],"invasive":[69],"divided":[73],"into":[74,160],"two":[75,172],"subgroups":[76],"by":[77,106],"their":[78,93],"significantly":[79,94,162],"(P=0.0003)":[80,95],"different":[81,96,163],"(2.0":[88],"10.3%,":[90],"respectively)":[91],"nonmodal":[101],"content":[103],"values":[104,178],"determined":[105],"the":[107,130,145,157,207,215],"Stemline":[108],"Scatter":[109],"Index":[110],"(SSI),":[111],"measure":[113],"genomic":[115,196],"instability.":[116],"demonstrated":[124],"positive,":[126],"linear":[127],"correlation":[128],"corresponding":[131],"SSI":[132],"(r=0.82,":[133],"P<0.0001)":[134],"loss":[136,199],"tissue":[138,201],"differentiation":[139],"(r=0.78,":[140],"P<0.0001).":[141],"Our":[142],"results":[143,189],"indicate":[144],"as":[152,221],"being":[153],"sufficient":[154],"to":[155],"divide":[156],"investigated":[158],"three":[161],"groups:":[164],"benign":[165],"no":[168],"aberrations,":[170],"tumour":[174],"types":[175],"2.1":[180],"9.6%":[182],"defects,":[185],"respectively.":[186],"Together,":[187],"these":[188],"demonstrate":[190],"correlate":[194],"instability":[197],"differentiation.":[202],"Furthermore,":[203],"this":[204],"study":[205],"shows":[206],"feasibility":[208],"FNAB":[213],"suggests":[218],"possessing":[222],"diagnostic":[223],"prognostic":[225],"value.":[226]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}