{"id":"https://openalex.org/W2004805936","doi":"https://doi.org/10.1073/pnas.81.19.6240","title":"Differential sleep-promoting effects of five sleep substances nocturnally infused in unrestrained rats.","display_name":"Differential sleep-promoting effects of five sleep substances nocturnally infused in unrestrained rats.","publication_year":1984,"publication_date":"1984-10-01","ids":{"openalex":"https://openalex.org/W2004805936","doi":"https://doi.org/10.1073/pnas.81.19.6240","mag":"2004805936","pmid":"https://pubmed.ncbi.nlm.nih.gov/6592612","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/391896"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.81.19.6240","doi":"https://doi.org/10.1073/pnas.81.19.6240","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.81.19.6240","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC391896","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014577195","display_name":"Seiji Inoue","orcid":"https://orcid.org/0009-0000-5872-0383","observed_orcids":["https://orcid.org/0009-0000-5872-0383"]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210165886","display_name":"Research Corporation of The University of Hawaii","ror":"https://ror.org/05wd11c32","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210165886"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"S Inou\u00e9","raw_affiliation_strings":["Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","Research Development Corporation of Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","institution_ids":[]},{"raw_affiliation_string":"Research Development Corporation of Japan,","institution_ids":["https://openalex.org/I4210165886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102137265","display_name":"Kazuki Honda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210165886","display_name":"Research Corporation of The University of Hawaii","ror":"https://ror.org/05wd11c32","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210165886"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"K Honda","raw_affiliation_strings":["Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","Research Development Corporation of Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","institution_ids":[]},{"raw_affiliation_string":"Research Development Corporation of Japan,","institution_ids":["https://openalex.org/I4210165886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087982989","display_name":"Yasuo Komoda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I125602781","display_name":"Tokyo Medical and Dental University","ror":"https://ror.org/051k3eh31","country_code":"JP","type":"education","lineage":["https://openalex.org/I125602781","https://openalex.org/I4400009020"]},{"id":"https://openalex.org/I4210165886","display_name":"Research Corporation of The University of Hawaii","ror":"https://ror.org/05wd11c32","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210165886"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Y Komoda","raw_affiliation_strings":["Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","Research Development Corporation of Japan,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Kanda-Surugadai 2-3-10, Chiyoda-ku, Tokyo 101; tNational Institute for Physiological Sciences,","institution_ids":["https://openalex.org/I125602781"]},{"raw_affiliation_string":"Myodaiji, Okazaki 444; and tHayaishi Bioinformation Transfer Project,","institution_ids":[]},{"raw_affiliation_string":"Research Development Corporation of Japan,","institution_ids":["https://openalex.org/I4210165886"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009990752","display_name":"Koji Uchizono","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205143321","display_name":"Osaka Medical and Pharmaceutical University","ror":"https://ror.org/01y2kdt21","country_code":"JP","type":"education","lineage":["https://openalex.org/I205143321"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Uchizono","raw_affiliation_strings":["Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan","institution_ids":["https://openalex.org/I205143321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032405444","display_name":"R Ueno","orcid":"https://orcid.org/0000-0003-4008-8871","observed_orcids":["https://orcid.org/0000-0003-4008-8871"]},"institutions":[{"id":"https://openalex.org/I205143321","display_name":"Osaka Medical and Pharmaceutical University","ror":"https://ror.org/01y2kdt21","country_code":"JP","type":"education","lineage":["https://openalex.org/I205143321"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"R Ueno","raw_affiliation_strings":["Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan","institution_ids":["https://openalex.org/I205143321"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064701201","display_name":"Osamu Hayaishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205143321","display_name":"Osaka Medical and Pharmaceutical University","ror":"https://ror.org/01y2kdt21","country_code":"JP","type":"education","lineage":["https://openalex.org/I205143321"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"O Hayaishi","raw_affiliation_strings":["Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osaka Medical College, Daigakumachi 2-7, Takatsuki 569, Japan","institution_ids":["https://openalex.org/I205143321"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0888,"has_fulltext":false,"cited_by_count":99,"citation_normalized_percentile":{"value":0.94122846,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"81","issue":"19","first_page":"6240","last_page":"6244"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/delta-sleep-inducing-peptide","display_name":"delta sleep-inducing peptide","score":0.9190000295639038},{"id":"https://openalex.org/keywords/muramyl-dipeptide","display_name":"muramyl dipeptide","score":0.9409999847412109},{"id":"https://openalex.org/keywords/prostaglandin-d2","display_name":"prostaglandin D2","score":0.9789999723434448},{"id":"https://openalex.org/keywords/uridine","display_name":"uridine","score":1.0},{"id":"https://openalex.org/keywords/slow-wave-sleep","display_name":"slow-wave sleep","score":0.949999988079071},{"id":"https://openalex.org/keywords/rem-sleep","display_name":"REM sleep","score":0.9950000047683716},{"id":"https://openalex.org/keywords/intracerebroventricular-infusion","display_name":"intracerebroventricular infusion","score":0.8870000243186951},{"id":"https://openalex.org/keywords/sleep-deprivation","display_name":"sleep deprivation","score":0.7300000190734863},{"id":"https://openalex.org/keywords/brain-temperature","display_name":"brain temperature","score":0.7839999794960022},{"id":"https://openalex.org/keywords/sleep-regulation","display_name":"sleep regulation","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.852152943611145},{"id":"https://openalex.org/C110539466","wikidata":"https://www.wikidata.org/wiki/Q3964845","display_name":"Slow-wave sleep","level":3,"score":0.6956357359886169},{"id":"https://openalex.org/C31094802","wikidata":"https://www.wikidata.org/wiki/Q7539756","display_name":"Sleep induction","level":3,"score":0.5870854258537292},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5659177899360657},{"id":"https://openalex.org/C63759246","wikidata":"https://www.wikidata.org/wiki/Q7539762","display_name":"Sleep onset","level":3,"score":0.5360790491104126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4929182529449463},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4902392029762268},{"id":"https://openalex.org/C207743973","wikidata":"https://www.wikidata.org/wiki/Q2623205","display_name":"Delta wave","level":4,"score":0.45171666145324707},{"id":"https://openalex.org/C2779213384","wikidata":"https://www.wikidata.org/wiki/Q211402","display_name":"Rapid eye movement sleep","level":3,"score":0.41405269503593445},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35431721806526184},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.33285701274871826},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.27968114614486694},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.22613242268562317},{"id":"https://openalex.org/C2781210498","wikidata":"https://www.wikidata.org/wiki/Q1869874","display_name":"Insomnia","level":2,"score":0.21833455562591553},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000119","descriptor_name":"Acetylmuramyl-Alanyl-Isoglutamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003701","descriptor_name":"Delta Sleep-Inducing Peptide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006020","descriptor_name":"Glycopeptides","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011457","descriptor_name":"Prostaglandins D","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012895","descriptor_name":"Sleep, REM","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014529","descriptor_name":"Uridine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D015230","descriptor_name":"Prostaglandin D2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.81.19.6240","doi":"https://doi.org/10.1073/pnas.81.19.6240","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.81.19.6240","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:64278","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC391896","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:391896","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/391896","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:6592612","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6592612","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:64278","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC391896","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309791","display_name":"Suzuken Memorial Foundation","ror":"https://ror.org/03yvcwz92"},{"id":"https://openalex.org/F4320310466","display_name":"Universit\u00e4t Basel","ror":"https://ror.org/02s6k3f65"},{"id":"https://openalex.org/F4320323874","display_name":"Universit\u00e4t Z\u00fcrich","ror":"https://ror.org/02crff812"},{"id":"https://openalex.org/F4320333003","display_name":"Chugai Pharmaceutical","ror":"https://ror.org/01vepzj85"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W594697724","https://openalex.org/W1559956276","https://openalex.org/W1976612946","https://openalex.org/W1987522424","https://openalex.org/W1989246693","https://openalex.org/W1999344041","https://openalex.org/W2001812566","https://openalex.org/W2004834257","https://openalex.org/W2020414910","https://openalex.org/W2066270109","https://openalex.org/W2079112878","https://openalex.org/W2115576097","https://openalex.org/W2171389116","https://openalex.org/W2173973727","https://openalex.org/W2413619006","https://openalex.org/W2437561641","https://openalex.org/W2465173313","https://openalex.org/W2465911495","https://openalex.org/W2887407214"],"related_works":["https://openalex.org/W1968993049","https://openalex.org/W2018423683","https://openalex.org/W2059356984","https://openalex.org/W4214854855","https://openalex.org/W2409054284","https://openalex.org/W2046381747","https://openalex.org/W2002930297","https://openalex.org/W1968797569","https://openalex.org/W2079112878","https://openalex.org/W3046906343"],"abstract_inverted_index":{"Sleep-inducing":[0],"and":[1,45,106],"sleep-maintaining":[2],"effects":[3,50],"of":[4,65,73,84,97,110,126],"five":[5],"different":[6],"putative":[7],"sleep":[8,44,47,61,78,98,121],"substances":[9],"were":[10,51],"compared":[11],"by":[12],"the":[13,49,63,66,123,127],"same":[14],"nocturnal":[15],"10-hr":[16],"intracerebroventricular":[17],"infusion":[18,67,128],"technique":[19],"in":[20,40,62,104,119,139,142],"otherwise":[21],"saline-infused,":[22],"freely":[23],"moving":[24],"male":[25],"rats.":[26],"Delta-sleep-inducing":[27],"peptide":[28],"(2.5":[29],"nmol),":[30],"which":[31],"induces":[32],"electroencephalogram":[33],"delta":[34],"(slow)-wave":[35],"patterns,":[36],"was":[37,79,101,116],"rapidly":[38],"effective":[39,103,118],"increasing":[41],"both":[42,108],"slow-wave":[43,60],"paradoxical":[46,77,143],"but":[48,136],"not":[52,80],"long-lasting.":[53],"Muramyl":[54],"dipeptide":[55],"(2":[56,87],"nmol)":[57,115],"induced":[58],"excessive":[59],"middle":[64],"period,":[68],"accompanying":[69],"a":[70,90,134],"simultaneous":[71],"elevation":[72],"brain":[74],"temperature.":[75],"However,":[76],"affected.":[81],"Component":[82],"B":[83],"sleep-promoting":[85],"substance":[86,147],"brainstem":[88],"equivalents),":[89],"partially":[91],"purified":[92],"extract":[93],"from":[94],"rats":[95],"deprived":[96],"for":[99],"24-hr,":[100],"markedly":[102],"inducing":[105],"maintaining":[107],"kinds":[109],"sleep.":[111,144],"Prostaglandin":[112],"D2":[113],"(0.36":[114],"more":[117],"enhancing":[120],"at":[122],"later":[124],"period":[125],"period.":[129],"Uridine":[130],"(10":[131],"pmol)":[132],"caused":[133],"mild":[135],"long-lasting":[137],"increase":[138],"sleep,":[140],"especially":[141],"Thus,":[145],"each":[146],"exhibited":[148],"compound-specific":[149],"sleep-modulating":[150],"properties.":[151]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}