{"id":"https://openalex.org/W2004707866","doi":"https://doi.org/10.1007/bf00932193","title":"Induction of complement-sensitivity inLeishmania amazonensis metacyclic promastigotes by protease treatment but not by specific antibodies","display_name":"Induction of complement-sensitivity inLeishmania amazonensis metacyclic promastigotes by protease treatment but not by specific antibodies","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2004707866","doi":"https://doi.org/10.1007/bf00932193","mag":"2004707866","pmid":"https://pubmed.ncbi.nlm.nih.gov/8327457"},"language":"en","primary_location":{"id":"doi:10.1007/bf00932193","doi":"https://doi.org/10.1007/bf00932193","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00932193","pdf_url":null,"source":{"id":"https://openalex.org/S155128447","display_name":"Parasitology Research","issn_l":"0044-3255","issn":["0044-3255","0932-0113","1432-1955"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasitology Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.RI_UFBA:oai:192.168.11:11:ri/8716","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081718122","display_name":"Neci Matos Soares","orcid":"https://orcid.org/0000-0003-1409-9884","observed_orcids":["https://orcid.org/0000-0003-1409-9884"]},"institutions":[{"id":"https://openalex.org/I4405286606","display_name":"Instituto Gon\u00e7alo Moniz","ror":"https://ror.org/02kqr5716","country_code":"BR","type":"government","lineage":["https://openalex.org/I4405286606","https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"N. M. Soares","raw_affiliation_strings":["Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Gon\u00e7alo Moniz, FIOCRUZ, Salvador, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Gon\u00e7alo Moniz, FIOCRUZ, Salvador, Brazil","institution_ids":["https://openalex.org/I4405286606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015047591","display_name":"Edgar M. Carvalho","orcid":"https://orcid.org/0000-0002-2697-8002","observed_orcids":["https://orcid.org/0000-0002-2697-8002"]},"institutions":[{"id":"https://openalex.org/I126158947","display_name":"Universidade Federal da Bahia","ror":"https://ror.org/03k3p7647","country_code":"BR","type":"education","lineage":["https://openalex.org/I126158947"]},{"id":"https://openalex.org/I4210088441","display_name":"Complexo Hospitalar Universit\u00e1rio Professor Edgard Santos","ror":"https://ror.org/006k05x61","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210088441"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"E. M. Carvalho","raw_affiliation_strings":["Hospital Professor Edgard Santos, Universidade Federal da Bahia, 40000, Salvador, Brazil","Hospital Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Professor Edgard Santos, Universidade Federal da Bahia, 40000, Salvador, Brazil","institution_ids":["https://openalex.org/I126158947","https://openalex.org/I4210088441"]},{"raw_affiliation_string":"Hospital Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil","institution_ids":["https://openalex.org/I126158947","https://openalex.org/I4210088441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035155045","display_name":"Rosa T. Pinho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286966","display_name":"Instituto Oswaldo Cruz","ror":"https://ror.org/03pww0c55","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"R. T. Pinho","raw_affiliation_strings":["Departmento de Imunologia, Instituto Oswaldo Cruz, FIOCRUZ, 21040, Rio de Janeiro, Brazil","Departmento de Imunologia, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departmento de Imunologia, Instituto Oswaldo Cruz, FIOCRUZ, 21040, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]},{"raw_affiliation_string":"Departmento de Imunologia, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil","institution_ids":["https://openalex.org/I4405286966","https://openalex.org/I52325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108546201","display_name":"Lain C. Pontes de Carvalho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405286606","display_name":"Instituto Gon\u00e7alo Moniz","ror":"https://ror.org/02kqr5716","country_code":"BR","type":"government","lineage":["https://openalex.org/I4405286606","https://openalex.org/I52325"]},{"id":"https://openalex.org/I52325","display_name":"Funda\u00e7\u00e3o Oswaldo Cruz","ror":"https://ror.org/04jhswv08","country_code":"BR","type":"facility","lineage":["https://openalex.org/I52325"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"L. C. Pontes de Carvalho","raw_affiliation_strings":["Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Goncalo Moniz, FIOCRUZ, 41945, Salvador, Brazil","Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Gon\u00e7alo Moniz, Fiocruz, Salvador, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Goncalo Moniz, FIOCRUZ, 41945, Salvador, Brazil","institution_ids":["https://openalex.org/I4405286606","https://openalex.org/I52325"]},{"raw_affiliation_string":"Laborat\u00f3rio Avan\u00e7ado de Sa\u00fade P\u00fablica, Centro de Pesquisas Gon\u00e7alo Moniz, Fiocruz, Salvador, Brazil","institution_ids":["https://openalex.org/I4405286606"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4590,"currency":"USD","value_usd":4590},"apc_paid":null,"fwci":1.3355,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.81180338,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"79","issue":"4","first_page":"340","last_page":"342"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10823","display_name":"Research on Leishmaniasis Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10890","display_name":"Trypanosoma species research and implications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leishmania-amazonensis","display_name":"Leishmania amazonensis","score":0.968999981880188},{"id":"https://openalex.org/keywords/metacyclic-promastigotes","display_name":"metacyclic promastigotes","score":0.9330000281333923},{"id":"https://openalex.org/keywords/complement-sensitivity","display_name":"complement sensitivity","score":0.972000002861023},{"id":"https://openalex.org/keywords/protease-treatment","display_name":"protease treatment","score":0.8600000143051147},{"id":"https://openalex.org/keywords/antibody-independent-complement-activation","display_name":"antibody-independent complement activation","score":0.45899999141693115},{"id":"https://openalex.org/keywords/complement-resistance","display_name":"complement resistance","score":0.41200000047683716}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8647128343582153},{"id":"https://openalex.org/C190139176","wikidata":"https://www.wikidata.org/wiki/Q598976","display_name":"Medical microbiology","level":2,"score":0.6626466512680054},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6474730968475342},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.6353256106376648},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5781797766685486},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5466365218162537},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.500084400177002},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.47520241141319275},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.21792098879814148},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10565030574798584}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000913","descriptor_name":"Antibodies, Protozoan","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003167","descriptor_name":"Complement Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007894","descriptor_name":"Leishmania mexicana","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007894","descriptor_name":"Leishmania mexicana","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014357","descriptor_name":"Trypsin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1007/bf00932193","doi":"https://doi.org/10.1007/bf00932193","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf00932193","pdf_url":null,"source":{"id":"https://openalex.org/S155128447","display_name":"Parasitology Research","issn_l":"0044-3255","issn":["0044-3255","0932-0113","1432-1955"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasitology Research","raw_type":"journal-article"},{"id":"pmid:8327457","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8327457","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasitology research","raw_type":"Journal Article"},{"id":"pmh:oai:agregador.ibict.br.RI_UFBA:oai:192.168.11:11:ri/8716","doi":null,"is_oa":true,"landing_page_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.RI_UFBA:oai:192.168.11:11:ri/8716","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:americanae.aecid.es:2317639","doi":null,"is_oa":true,"landing_page_url":"https://www.arca.fiocruz.br/handle/icict/8340","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da FIOCRUZ (ARCA)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:www.arca.fiocruz.br:icict/8340","doi":null,"is_oa":true,"landing_page_url":"https://www.arca.fiocruz.br/handle/icict/8340","pdf_url":"https://www.arca.fiocruz.br/handle/icict/8340","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da FIOCRUZ (ARCA)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:arca.fiocruz.br:icict/8340","doi":null,"is_oa":true,"landing_page_url":"https://arca.fiocruz.br/handle/icict/8340","pdf_url":null,"source":{"id":"https://openalex.org/S7407055450","display_name":"Arca - Reposit\u00f3rio Institucional da Fiocruz","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:agregador.ibict.br.RI_UFBA:oai:192.168.11:11:ri/8716","doi":null,"is_oa":true,"landing_page_url":"https://www.rcaap.pt/detail.jsp?id=oai:agregador.ibict.br.RI_UFBA:oai:192.168.11:11:ri/8716","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004707866.pdf","grobid_xml":"https://content.openalex.org/works/W2004707866.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W89695407","https://openalex.org/W1492856261","https://openalex.org/W1521195001","https://openalex.org/W1776020366","https://openalex.org/W1949772429","https://openalex.org/W1963968233","https://openalex.org/W1970030817","https://openalex.org/W2009055218","https://openalex.org/W2056582402","https://openalex.org/W2071190956","https://openalex.org/W2082071395","https://openalex.org/W2082978673","https://openalex.org/W2086436315","https://openalex.org/W2260543582","https://openalex.org/W2338770458","https://openalex.org/W2396674967","https://openalex.org/W2419443274","https://openalex.org/W2461757281","https://openalex.org/W4211009645"],"related_works":["https://openalex.org/W1601506490","https://openalex.org/W2157875324","https://openalex.org/W1971178554","https://openalex.org/W3109133911","https://openalex.org/W3101947977","https://openalex.org/W6958162305","https://openalex.org/W3027490153","https://openalex.org/W3022319311","https://openalex.org/W2911533564","https://openalex.org/W2948709970"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}