{"id":"https://openalex.org/W2004686592","doi":"https://doi.org/10.1016/s0016-5085(00)83213-8","title":"Red meat and colon cancer: The cytotoxic and hyperproliferative effects of low concentrations of dietary heme","display_name":"Red meat and colon cancer: The cytotoxic and hyperproliferative effects of low concentrations of dietary heme","publication_year":2000,"publication_date":"2000-04-01","ids":{"openalex":"https://openalex.org/W2004686592","doi":"https://doi.org/10.1016/s0016-5085(00)83213-8","mag":"2004686592"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(00)83213-8","doi":"https://doi.org/10.1016/s0016-5085(00)83213-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","pdf_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027060657","display_name":"Aloys L.A. Sesink","orcid":"https://orcid.org/0009-0006-7141-0324","observed_orcids":["https://orcid.org/0009-0006-7141-0324"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aloys L. Sesink","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113525503","display_name":"D S Termont","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Denise S. Termont","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111967385","display_name":"Jan H. Kleibeuker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan H. Kleibeuker","raw_affiliation_strings":["Guided Treatment in Optimal Selected Cancer Patients (GUTS)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guided Treatment in Optimal Selected Cancer Patients (GUTS)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108369563","display_name":"Roelof van der Meer","orcid":"https://orcid.org/0000-0002-7612-7660","observed_orcids":["https://orcid.org/0000-0002-7612-7660"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roelof Van der Meer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"118","issue":"4","first_page":"A282","last_page":"A282"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.2549000084400177,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.12520000338554382,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10333","display_name":"Meat and Animal Product Quality","score":0.07970000058412552,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/red-meat","display_name":"red meat","score":0.9580000042915344},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9359999895095825},{"id":"https://openalex.org/keywords/heme-iron","display_name":"heme iron","score":0.6539999842643738},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8899999856948853},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9240000247955322},{"id":"https://openalex.org/keywords/colorectal-carcinogenesis","display_name":"colorectal carcinogenesis","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2778089274","wikidata":"https://www.wikidata.org/wiki/Q3243069","display_name":"Red meat","level":2,"score":0.7355848550796509},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.7253352403640747},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7203042507171631},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.659400224685669},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43289974331855774},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4314059317111969},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42703548073768616},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41915076971054077},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.37157636880874634},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33568698167800903},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20831021666526794},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.05400243401527405},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/s0016-5085(00)83213-8","doi":"https://doi.org/10.1016/s0016-5085(00)83213-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","pdf_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/ebe6ed0e-79d8-4b4c-9ecc-7e876a567f1d","doi":null,"is_oa":false,"landing_page_url":"https://www.rug.nl/research/portal/en/publications/red-meat-and-colon-cancer(ebe6ed0e-79d8-4b4c-9ecc-7e876a567f1d).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Gastroenterology, 118(4), A282 - A282","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(00)83213-8","doi":"https://doi.org/10.1016/s0016-5085(00)83213-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","pdf_url":"https://doi.org/10.1016/s0016-5085(00)83213-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004686592.pdf","grobid_xml":"https://content.openalex.org/works/W2004686592.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2048038357","https://openalex.org/W1969769706","https://openalex.org/W2099219641","https://openalex.org/W4291213152","https://openalex.org/W2163516381","https://openalex.org/W2047075042","https://openalex.org/W2465321463","https://openalex.org/W2587035202","https://openalex.org/W2566678910","https://openalex.org/W1984930382"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}