{"id":"https://openalex.org/W2004674477","doi":"https://doi.org/10.1016/s0140-6736(76)90296-8","title":"ORAL CONTRACEPTIVES, ANTITHROMBIN-III ACTIVITY, AND POSTOPERATIVE DEEP-VEIN THROMBOSIS","display_name":"ORAL CONTRACEPTIVES, ANTITHROMBIN-III ACTIVITY, AND POSTOPERATIVE DEEP-VEIN THROMBOSIS","publication_year":1976,"publication_date":"1976-03-01","ids":{"openalex":"https://openalex.org/W2004674477","doi":"https://doi.org/10.1016/s0140-6736(76)90296-8","mag":"2004674477","pmid":"https://pubmed.ncbi.nlm.nih.gov/55783"},"language":"en","primary_location":{"id":"doi:10.1016/s0140-6736(76)90296-8","doi":"https://doi.org/10.1016/s0140-6736(76)90296-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(76)90296-8","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108937273","display_name":"S Sagar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Sagar","raw_affiliation_strings":["Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon","institution_ids":["https://openalex.org/I4210153400"]}]},{"author_position":"middle","author":{"id":null,"display_name":"D.P. Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D.P. Thomas","raw_affiliation_strings":["Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon","institution_ids":["https://openalex.org/I4210153400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113548979","display_name":"Jeffrey D. Stamatakis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J.D. Stamatakis","raw_affiliation_strings":["Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon","institution_ids":["https://openalex.org/I4210153400"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108684235","display_name":"V V Kakkar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153400","display_name":"King's College Hospital","ror":"https://ror.org/044nptt90","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V.V. Kakkar","raw_affiliation_strings":["Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, King's College Hospital Medical School, Denmark Hill, London SE5 8RX, United Kingdon","institution_ids":["https://openalex.org/I4210153400"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210153400"],"apc_list":{"value":7890,"currency":"USD","value_usd":7890},"apc_paid":null,"fwci":23.4377,"has_fulltext":false,"cited_by_count":142,"citation_normalized_percentile":{"value":0.99459194,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"307","issue":"7958","first_page":"509","last_page":"511"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.046799998730421066,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-contraceptives","display_name":"oral contraceptives","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antithrombin-iii","display_name":"antithrombin III","score":0.8450000286102295},{"id":"https://openalex.org/keywords/deep-vein-thrombosis","display_name":"deep vein thrombosis","score":0.9750000238418579},{"id":"https://openalex.org/keywords/postoperative-thrombosis","display_name":"postoperative thrombosis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/emergency-abdominal-surgery","display_name":"emergency abdominal surgery","score":0.7630000114440918},{"id":"https://openalex.org/keywords/tooth-extraction","display_name":"tooth extraction","score":0.6919999718666077},{"id":"https://openalex.org/keywords/fibrinogen-uptake-test","display_name":"fibrinogen uptake test","score":0.7870000004768372},{"id":"https://openalex.org/keywords/heparin-prophylaxis","display_name":"heparin prophylaxis","score":0.8769999742507935}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8993982076644897},{"id":"https://openalex.org/C2779026020","wikidata":"https://www.wikidata.org/wiki/Q416336","display_name":"Antithrombin","level":3,"score":0.8086869120597839},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.6601130962371826},{"id":"https://openalex.org/C2778959117","wikidata":"https://www.wikidata.org/wiki/Q430892","display_name":"Deep vein","level":3,"score":0.5788548588752747},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.5316734313964844},{"id":"https://openalex.org/C2778432500","wikidata":"https://www.wikidata.org/wiki/Q3704732","display_name":"Antithrombin III deficiency","level":4,"score":0.4980638027191162},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.4425725042819977},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.4406869113445282},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.42233967781066895},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4169454872608185},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28874456882476807}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000361","descriptor_name":"Agammaglobulinemia","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D000510","descriptor_name":"Alpha-Globulins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D000990","descriptor_name":"Antithrombin III","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001064","descriptor_name":"Appendicitis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006493","descriptor_name":"Heparin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011182","descriptor_name":"Postoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013924","descriptor_name":"Thrombophlebitis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D013924","descriptor_name":"Thrombophlebitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014081","descriptor_name":"Tooth Extraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020152","descriptor_name":"Antithrombin III Deficiency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D045166","descriptor_name":"Estradiol Congeners","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0140-6736(76)90296-8","doi":"https://doi.org/10.1016/s0140-6736(76)90296-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0140-6736(76)90296-8","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet","raw_type":"journal-article"},{"id":"pmid:55783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/55783","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lancet (London, England)","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1593132442","https://openalex.org/W1658016274","https://openalex.org/W1963505457","https://openalex.org/W1973619994","https://openalex.org/W1991151971","https://openalex.org/W2029413749","https://openalex.org/W2039013570","https://openalex.org/W2044471714","https://openalex.org/W2046276801","https://openalex.org/W2082143091","https://openalex.org/W2095565910","https://openalex.org/W3145556378"],"related_works":["https://openalex.org/W2992958656","https://openalex.org/W2069546451","https://openalex.org/W2060284351","https://openalex.org/W2045778633","https://openalex.org/W1599957815","https://openalex.org/W2411989424","https://openalex.org/W2056113186","https://openalex.org/W132072165","https://openalex.org/W2884288293","https://openalex.org/W2036821565"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}