{"id":"https://openalex.org/W2004656106","doi":"https://doi.org/10.1006/bbrc.1998.9530","title":"A Multifunctional Transcription Factor (A1p145) Regulates the Smooth Muscle Phenotype in Mesangial Cells","display_name":"A Multifunctional Transcription Factor (A1p145) Regulates the Smooth Muscle Phenotype in Mesangial Cells","publication_year":1998,"publication_date":"1998-11-01","ids":{"openalex":"https://openalex.org/W2004656106","doi":"https://doi.org/10.1006/bbrc.1998.9530","mag":"2004656106","pmid":"https://pubmed.ncbi.nlm.nih.gov/9826522"},"language":"en","primary_location":{"id":"doi:10.1006/bbrc.1998.9530","doi":"https://doi.org/10.1006/bbrc.1998.9530","is_oa":false,"landing_page_url":"https://doi.org/10.1006/bbrc.1998.9530","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091790413","display_name":"Hiroya Takeoka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroya Takeoka","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Division of Artificial Kidneys, Faculty of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Kyoto, Sakyo-ku, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Division of Artificial Kidneys, Faculty of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Kyoto, Sakyo-ku, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019170168","display_name":"Noriyuki Iehara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriyuki Iehara","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043638480","display_name":"Motoko Uematsu-Yanagita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motoko Uematsu-Yanagita","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069412789","display_name":"Hideharu Abe","orcid":"https://orcid.org/0000-0002-1480-9674","observed_orcids":["https://orcid.org/0000-0002-1480-9674"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideharu Abe","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070796571","display_name":"Masaaki Sunamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Sunamoto","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102398216","display_name":"Yoshihiko Yamada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoshihiko Yamada","raw_affiliation_strings":["Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland, 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Developmental Biology, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland, 20892","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109115866","display_name":"Toru Kita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toru Kita","raw_affiliation_strings":["Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatric Medicine, Division of Clinical Bio-regulatory Science, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5132257851","display_name":"Toshio Doi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshio Doi","raw_affiliation_strings":["Division of Artificial Kidneys, Faculty of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Artificial Kidneys, Faculty of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":0.8384,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.7191108,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"252","issue":"2","first_page":"290","last_page":"295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.8790000081062317},{"id":"https://openalex.org/keywords/mesangial-cells","display_name":"mesangial cells","score":0.9390000104904175},{"id":"https://openalex.org/keywords/smooth-muscle-cell-phenotype","display_name":"smooth muscle cell phenotype","score":0.9079999923706055},{"id":"https://openalex.org/keywords/type-iv-collagen","display_name":"type IV collagen","score":0.8259999752044678},{"id":"https://openalex.org/keywords/smooth-muscle-alpha-actin","display_name":"smooth muscle actin","score":0.9819999933242798},{"id":"https://openalex.org/keywords/phenotypic-modulation","display_name":"phenotypic modulation","score":0.6990000009536743},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.6010000109672546},{"id":"https://openalex.org/keywords/antisense-rna","display_name":"antisense RNA","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5973170399665833},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5657378435134888},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5294532179832458},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5109557509422302},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.45130714774131775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4395281672477722},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4390745460987091},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39615097641944885},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.38221848011016846},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.37350666522979736},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3636133670806885},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3546462953090668},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12365168333053589},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05478808283805847},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005920","descriptor_name":"Glomerular Mesangium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D005920","descriptor_name":"Glomerular Mesangium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009130","descriptor_name":"Muscle, Smooth","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017931","descriptor_name":"DNA Primers","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020319","descriptor_name":"Oligodeoxyribonucleotides, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020319","descriptor_name":"Oligodeoxyribonucleotides, Antisense","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/bbrc.1998.9530","doi":"https://doi.org/10.1006/bbrc.1998.9530","is_oa":false,"landing_page_url":"https://doi.org/10.1006/bbrc.1998.9530","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:9826522","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9826522","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W38887023","https://openalex.org/W1485442163","https://openalex.org/W1949650266","https://openalex.org/W1978831674","https://openalex.org/W1981481692","https://openalex.org/W1992041665","https://openalex.org/W1993243592","https://openalex.org/W1993402154","https://openalex.org/W2001534689","https://openalex.org/W2003688210","https://openalex.org/W2013629550","https://openalex.org/W2040279078","https://openalex.org/W2049702083","https://openalex.org/W2053229508","https://openalex.org/W2056223190","https://openalex.org/W2063374742","https://openalex.org/W2105454524","https://openalex.org/W2126196172","https://openalex.org/W2128118061","https://openalex.org/W2128635872","https://openalex.org/W2128940002","https://openalex.org/W2141283516","https://openalex.org/W2145750252","https://openalex.org/W2165123145","https://openalex.org/W2170571176","https://openalex.org/W2221020875","https://openalex.org/W2413949809","https://openalex.org/W2417964770","https://openalex.org/W2418991305"],"related_works":["https://openalex.org/W2276713478","https://openalex.org/W1987135542","https://openalex.org/W3032923013","https://openalex.org/W2417782672","https://openalex.org/W1975916930","https://openalex.org/W2379381487","https://openalex.org/W2490131123","https://openalex.org/W2164938444","https://openalex.org/W3214269928","https://openalex.org/W4388048450"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}