{"id":"https://openalex.org/W2004642276","doi":"https://doi.org/10.1038/2211056a0","title":"Two-dimensional Resolution of Plasma Proteins by Combination of Polyacrylamide Disc and Gradient Gel Electrophoresis","display_name":"Two-dimensional Resolution of Plasma Proteins by Combination of Polyacrylamide Disc and Gradient Gel Electrophoresis","publication_year":1969,"publication_date":"1969-03-01","ids":{"openalex":"https://openalex.org/W2004642276","doi":"https://doi.org/10.1038/2211056a0","mag":"2004642276","pmid":"https://pubmed.ncbi.nlm.nih.gov/5774398"},"language":"en","primary_location":{"id":"doi:10.1038/2211056a0","doi":"https://doi.org/10.1038/2211056a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/2211056a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020630625","display_name":"Joel Margolis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802384191","display_name":"Children's Hospital at Westmead","ror":"https://ror.org/05k0s5494","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802384191"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J. MARGOLIS","raw_affiliation_strings":["Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney, NSW, 2050","Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney, NSW, 2050","institution_ids":["https://openalex.org/I2802384191"]},{"raw_affiliation_string":"Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney","institution_ids":["https://openalex.org/I2802384191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112388723","display_name":"Kenneth G Kenrick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802384191","display_name":"Children's Hospital at Westmead","ror":"https://ror.org/05k0s5494","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2802384191"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"K. G. KENRICK","raw_affiliation_strings":["Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney, NSW, 2050","Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney, NSW, 2050","institution_ids":["https://openalex.org/I2802384191"]},{"raw_affiliation_string":"Children's Medical Research Foundation, Royal Alexandra Hospital for Children, Camperdown, Sydney","institution_ids":["https://openalex.org/I2802384191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2802384191"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":1.3019,"has_fulltext":false,"cited_by_count":91,"citation_normalized_percentile":{"value":0.74174116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"221","issue":"5185","first_page":"1056","last_page":"1057"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9014000296592712,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9014000296592712,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.07609999924898148,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasma-proteins","display_name":"plasma proteins","score":0.9760000109672546},{"id":"https://openalex.org/keywords/gradient-gel-electrophoresis","display_name":"gradient gel electrophoresis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/molecular-sieving","display_name":"molecular sieving","score":0.7889999747276306},{"id":"https://openalex.org/keywords/electrophoretic-mobility","display_name":"electrophoretic mobility","score":0.828000009059906},{"id":"https://openalex.org/keywords/protein-migration","display_name":"protein migration","score":0.3140000104904175}],"concepts":[{"id":"https://openalex.org/C40250595","wikidata":"https://www.wikidata.org/wiki/Q185098","display_name":"Electrophoresis","level":2,"score":0.7957913875579834},{"id":"https://openalex.org/C2778862431","wikidata":"https://www.wikidata.org/wiki/Q416002","display_name":"Polyacrylamide","level":2,"score":0.698733925819397},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.5771595239639282},{"id":"https://openalex.org/C101660505","wikidata":"https://www.wikidata.org/wiki/Q898301","display_name":"Polyacrylamide gel electrophoresis","level":3,"score":0.5501863360404968},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5483201742172241},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.48000043630599976},{"id":"https://openalex.org/C35859425","wikidata":"https://www.wikidata.org/wiki/Q384609","display_name":"Gel electrophoresis of proteins","level":4,"score":0.42051199078559875},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.36544233560562134},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2193433940410614},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15280750393867493},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.05913165211677551},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000180","descriptor_name":"Acrylic Resins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001797","descriptor_name":"Blood Protein Electrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004589","descriptor_name":"Electrophoresis, Disc","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005782","descriptor_name":"Gels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/2211056a0","doi":"https://doi.org/10.1038/2211056a0","is_oa":false,"landing_page_url":"https://doi.org/10.1038/2211056a0","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:5774398","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5774398","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1970617599","https://openalex.org/W1978754520","https://openalex.org/W1983587311","https://openalex.org/W1993625807","https://openalex.org/W2015251911","https://openalex.org/W2034625412","https://openalex.org/W2054446576","https://openalex.org/W2071222197","https://openalex.org/W2111301002","https://openalex.org/W2132068224"],"related_works":["https://openalex.org/W1994048323","https://openalex.org/W1983587311","https://openalex.org/W2278285467","https://openalex.org/W2973988734","https://openalex.org/W1986603280","https://openalex.org/W2206019472","https://openalex.org/W2015251911","https://openalex.org/W4252895577","https://openalex.org/W2553179899","https://openalex.org/W1987439538"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}