{"id":"https://openalex.org/W2004546191","doi":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","title":"Electrophysiological properties of electrical synapses between rat sympathetic preganglionic neurones in vitro","display_name":"Electrophysiological properties of electrical synapses between rat sympathetic preganglionic neurones in vitro","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W2004546191","doi":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","mag":"2004546191","pmid":"https://pubmed.ncbi.nlm.nih.gov/10457088","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2269542"},"language":"en","primary_location":{"id":"doi:10.1111/j.1469-7793.1999.0753n.x","doi":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","pdf_url":null,"source":{"id":"https://openalex.org/S2090548","display_name":"The Journal of Physiology","issn_l":"0022-3751","issn":["0022-3751","1469-7793"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2269542/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079209289","display_name":"Matthew F. Nolan","orcid":"https://orcid.org/0000-0003-1062-6501","observed_orcids":["https://orcid.org/0000-0003-1062-6501"]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Matthew F. Nolan","raw_affiliation_strings":["Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK","institution_ids":["https://openalex.org/I195460627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102078717","display_name":"Stephen D. Logan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen D. Logan","raw_affiliation_strings":["Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK,","institution_ids":["https://openalex.org/I195460627"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040623262","display_name":"David\u00a0C. Spanswick","orcid":"https://orcid.org/0000-0002-8129-8173","observed_orcids":["https://orcid.org/0000-0002-8129-8173"]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Spanswick","raw_affiliation_strings":["Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK,","institution_ids":["https://openalex.org/I195460627"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I195460627"],"apc_list":{"value":5400,"currency":"USD","value_usd":5400},"apc_paid":null,"fwci":0.6704,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.62505831,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"519","issue":"3","first_page":"753","last_page":"764"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.0502999983727932,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.030300000682473183,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electrical-synapses","display_name":"electrical synapses","score":0.9810000061988831},{"id":"https://openalex.org/keywords/gap-junctions","display_name":"gap junctions","score":0.7300000190734863},{"id":"https://openalex.org/keywords/spinal-cord-slices","display_name":"spinal cord slices","score":0.8019999861717224},{"id":"https://openalex.org/keywords/electrical-coupling","display_name":"electrical coupling","score":0.8619999885559082},{"id":"https://openalex.org/keywords/coupling-coefficient","display_name":"coupling coefficient","score":0.8299999833106995},{"id":"https://openalex.org/keywords/junctional-conductance","display_name":"junctional conductance","score":0.7110000252723694}],"concepts":[{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.7603612542152405},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.7453171014785767},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7446876764297485},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6448349356651306},{"id":"https://openalex.org/C4141045","wikidata":"https://www.wikidata.org/wiki/Q83183","display_name":"Depolarization","level":2,"score":0.595974862575531},{"id":"https://openalex.org/C181911157","wikidata":"https://www.wikidata.org/wiki/Q389844","display_name":"Membrane potential","level":2,"score":0.5570258498191833},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.5402154326438904},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5307502746582031},{"id":"https://openalex.org/C2908872077","wikidata":"https://www.wikidata.org/wiki/Q1187365","display_name":"Electrical Synapses","level":4,"score":0.47549211978912354},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.4518536627292633},{"id":"https://openalex.org/C54407271","wikidata":"https://www.wikidata.org/wiki/Q194277","display_name":"Action potential","level":3,"score":0.4287460446357727},{"id":"https://openalex.org/C179053475","wikidata":"https://www.wikidata.org/wiki/Q7662040","display_name":"Synaptic potential","level":4,"score":0.4273773431777954},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3832789957523346},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.35034477710723877},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.3466203510761261},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31671345233917236},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.12958797812461853},{"id":"https://openalex.org/C158157758","wikidata":"https://www.wikidata.org/wiki/Q232438","display_name":"Gap junction","level":3,"score":0.11937525868415833},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.11714628338813782},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09989869594573975},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001339","descriptor_name":"Autonomic Fibers, Preganglionic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018408","descriptor_name":"Patch-Clamp Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1469-7793.1999.0753n.x","doi":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1469-7793.1999.0753n.x","pdf_url":null,"source":{"id":"https://openalex.org/S2090548","display_name":"The Journal of Physiology","issn_l":"0022-3751","issn":["0022-3751","1469-7793"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Physiology","raw_type":"journal-article"},{"id":"pmid:10457088","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10457088","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of physiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2269542","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2269542/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Physiol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2269542","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2269542/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Physiol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W16541135","https://openalex.org/W162431773","https://openalex.org/W1521633888","https://openalex.org/W1549407977","https://openalex.org/W1588059035","https://openalex.org/W1631571478","https://openalex.org/W1889733078","https://openalex.org/W1953927931","https://openalex.org/W1956230030","https://openalex.org/W1971027471","https://openalex.org/W1983020085","https://openalex.org/W1985183665","https://openalex.org/W2004853618","https://openalex.org/W2010627844","https://openalex.org/W2029719613","https://openalex.org/W2030670571","https://openalex.org/W2031031033","https://openalex.org/W2035220073","https://openalex.org/W2042431572","https://openalex.org/W2051710352","https://openalex.org/W2053834193","https://openalex.org/W2056116232","https://openalex.org/W2057685701","https://openalex.org/W2063134736","https://openalex.org/W2079843155","https://openalex.org/W2087108004","https://openalex.org/W2090289611","https://openalex.org/W2101574428","https://openalex.org/W2107051929","https://openalex.org/W2153813372","https://openalex.org/W2158798405","https://openalex.org/W2160607236","https://openalex.org/W2163038565","https://openalex.org/W2397483734","https://openalex.org/W2408801304","https://openalex.org/W2412927807","https://openalex.org/W2509080906"],"related_works":["https://openalex.org/W2010627844","https://openalex.org/W1910835545","https://openalex.org/W7095200762","https://openalex.org/W1971255672","https://openalex.org/W1988797439","https://openalex.org/W2021440135","https://openalex.org/W1970703440","https://openalex.org/W7098240696","https://openalex.org/W7213709573","https://openalex.org/W3176595466"],"abstract_inverted_index":{"1.":[0],"The":[1],"electrophysiological":[2],"properties":[3,98],"of":[4,15,34,44,74,88,102,121,134,172,176,193,228,239,256,263],"electrical":[5,116,245],"synaptic":[6,104],"transmission":[7],"between":[8,31,85,197],"sympathetic":[9,258],"preganglionic":[10],"neurones":[11,46,200,217],"(SPNs)":[12],"in":[13,80,95,111,165,214],"slices":[14],"rat":[16],"spinal":[17],"cord":[18],"were":[19,67,109],"investigated":[20],"using":[21],"simultaneous":[22],"dual-electrode":[23],"patch-clamp":[24],"recordings.":[25],"Electrotonic":[26],"coupling":[27,77,84],"was":[28,91,180,201],"directly":[29],"demonstrated":[30],"21":[32],"pairs":[33,90],"SPNs.":[35],"2.":[36],"Coupling":[37],"coefficients":[38,78],"determined":[39,155],"from":[40,55],"the":[41,72,103,157,173,177],"steady-state":[42],"response":[43],"both":[45],"to":[47,58,93,182,254,265],"current":[48],"steps":[49],"injected":[50],"into":[51],"either":[52,81],"neurone":[53],"ranged":[54],"0.":[56],"02":[57],"0.48":[59],"(0.18":[60],"+/-":[61,64,136,140],"0.02,":[62],"mean":[63],"s.e.m.).":[65],"Synapses":[66],"bidirectional":[68],"and":[69,138,160,241,260],"symmetrical":[70],"for":[71],"majority":[73],"connections":[75],"with":[76,132,152],"similar":[79],"direction.":[82],"Asymmetrical":[83],"a":[86,122,128,229],"minority":[87],"cell":[89],"due":[92],"differences":[94],"passive":[96],"neuronal":[97],"rather":[99],"than":[100],"rectification":[101],"conductances.":[105],"3.":[106],"Action":[107],"potentials":[108,118,146,196],"manifest":[110],"adjoining":[112,231],"cells":[113],"as":[114],"biphasic":[115],"postsynaptic":[117,161],"(ePSPs),":[119],"composed":[120],"rapid":[123],"depolarising":[124],"component":[125,175],"followed":[126],"by":[127,156,203,221,225,244],"more":[129,188],"prolonged":[130],"hyperpolarisation":[131],"amplitudes":[133],"1.2":[135],"0.2":[137],"2.1":[139],"0.6":[141],"mV,":[142],"respectively.":[143],"4.":[144],"Postsynaptic":[145],"resembled":[147],"low-pass":[148],"filtered":[149],"presynaptic":[150,166,185],"spikes":[151,186],"frequency":[153,169],"dependence":[154],"junctional":[158],"conductance":[159],"membrane":[162,205],"properties.":[163],"Increases":[164],"action":[167,195],"potential":[168,206],"caused":[170],"attenuation":[171],"hyperpolarising":[174],"ePSP":[178],"that":[179],"attributed":[181],"shorter":[183],"duration":[184],"being":[187],"markedly":[189],"filtered.":[190],"5.":[191],"Synchronisation":[192],"spontaneous":[194],"electrotonically":[198],"coupled":[199],"driven":[202,220],"subthreshold":[204],"activity":[207,243],"resembling":[208],"repetitive":[209],"ePSPs.":[210],"Synchronous":[211],"spike":[212],"firing":[213,250],"previously":[215],"silent":[216],"could":[218],"be":[219],"suprathreshold":[222,226,242],"ePSPs":[223],"induced":[224],"depolarisation":[227],"single":[230],"neurone.":[232],"6.":[233],"These":[234],"data":[235],"characterise":[236],"reliable":[237],"communication":[238],"sub-":[240],"synapses":[246],"enabling":[247],"synchronised":[248],"SPN":[249],"which":[251],"may":[252],"contribute":[253],"generation":[255],"coherent":[257],"rhythms":[259],"promote":[261],"summation":[262],"inputs":[264],"postganglionic":[266],"neurones.":[267]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}