{"id":"https://openalex.org/W2004484191","doi":"https://doi.org/10.1212/wnl.53.5.1119","title":"Dysferlin is a surface membrane\u2013associated protein that is absent in Miyoshi myopathy","display_name":"Dysferlin is a surface membrane\u2013associated protein that is absent in Miyoshi myopathy","publication_year":1999,"publication_date":"1999-09-01","ids":{"openalex":"https://openalex.org/W2004484191","doi":"https://doi.org/10.1212/wnl.53.5.1119","mag":"2004484191","pmid":"https://pubmed.ncbi.nlm.nih.gov/10496277"},"language":"en","primary_location":{"id":"doi:10.1212/wnl.53.5.1119","doi":"https://doi.org/10.1212/wnl.53.5.1119","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.53.5.1119","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087755847","display_name":"Chie Matsuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"C. Matsuda","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073117349","display_name":"Masashi Aoki","orcid":"https://orcid.org/0000-0001-7284-1069","observed_orcids":["https://orcid.org/0000-0001-7284-1069"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"M. Aoki","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","MED - Medical Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]},{"raw_affiliation_string":"MED - Medical Sciences","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008182946","display_name":"Yukiko K Hayashi","orcid":"https://orcid.org/0000-0003-4043-1756","observed_orcids":["https://orcid.org/0000-0003-4043-1756"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Y.K. Hayashi","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006432577","display_name":"Mengfatt Ho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"M.F. Ho","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006328065","display_name":"Kiichi Arahata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"K. Arahata","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025571618","display_name":"Robert H. Brown","orcid":"https://orcid.org/0000-0001-6062-1528","observed_orcids":["https://orcid.org/0000-0001-6062-1528"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210103779","display_name":"National Center of Neurology and Psychiatry","ror":"https://ror.org/0254bmq54","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210103779"]},{"id":"https://openalex.org/I4405287400","display_name":"National Institute of Neuroscience","ror":"https://ror.org/052fnx536","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"R.H. Brown","raw_affiliation_strings":["From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Day Neuromuscular Research Laboratory (Drs. MatsudaAoki, Ho, and Brown), Massachusetts General Hospital\u2013East, Charlestown, MA; National Institute of Biosciences and Human Technology (Dr. Matsuda), Agency of Industrial Science and Technology, Tsukuba, Japan; Department of Neurology (Dr. Aoki), Tohoku University School of Medicine, Sendai, Japan; and Department of Neuromuscular Research (Y.K. Hayashi and Dr. Arahata), National Institute of Neuroscience, National Center of Neurology and","institution_ids":["https://openalex.org/I201537933","https://openalex.org/I4210087915","https://openalex.org/I4210103779","https://openalex.org/I4405287400"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6913,"has_fulltext":false,"cited_by_count":138,"citation_normalized_percentile":{"value":0.9396562,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"53","issue":"5","first_page":"1119","last_page":"1119"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.06289999932050705,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.03790000081062317,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dysferlin","display_name":"dysferlin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/miyoshi-myopathy","display_name":"Miyoshi myopathy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hereditary-myopathy","display_name":"hereditary myopathy","score":0.5690000057220459},{"id":"https://openalex.org/keywords/muscle-fiber-regeneration","display_name":"muscle fiber regeneration","score":0.3930000066757202},{"id":"https://openalex.org/keywords/muscle-fiber-necrosis","display_name":"muscle fiber necrosis","score":0.35499998927116394},{"id":"https://openalex.org/keywords/muscle-fiber-atrophy","display_name":"muscle fiber atrophy","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C37113945","wikidata":"https://www.wikidata.org/wiki/Q14885337","display_name":"Dysferlin","level":3,"score":0.9966335296630859},{"id":"https://openalex.org/C2778649560","wikidata":"https://www.wikidata.org/wiki/Q1531322","display_name":"Limb-girdle muscular dystrophy","level":4,"score":0.7856777906417847},{"id":"https://openalex.org/C3763915","wikidata":"https://www.wikidata.org/wiki/Q3331437","display_name":"Myogenesis","level":3,"score":0.7350594401359558},{"id":"https://openalex.org/C2779030066","wikidata":"https://www.wikidata.org/wiki/Q1137767","display_name":"Muscular dystrophy","level":2,"score":0.6674593091011047},{"id":"https://openalex.org/C2780394045","wikidata":"https://www.wikidata.org/wiki/Q412285","display_name":"Dystrophin","level":3,"score":0.6003935933113098},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.570002019405365},{"id":"https://openalex.org/C2777300911","wikidata":"https://www.wikidata.org/wiki/Q692536","display_name":"Myopathy","level":2,"score":0.5571472644805908},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4425016939640045},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.39361241459846497},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.3795052766799927},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.35453563928604126},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.28971153497695923},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2237667739391327},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.19693118333816528},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0764475166797638}],"mesh":[{"descriptor_ui":"D000073939","descriptor_name":"Dysferlin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D009132","descriptor_name":"Muscles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009136","descriptor_name":"Muscular Dystrophies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1212/wnl.53.5.1119","doi":"https://doi.org/10.1212/wnl.53.5.1119","is_oa":false,"landing_page_url":"https://doi.org/10.1212/wnl.53.5.1119","pdf_url":null,"source":{"id":"https://openalex.org/S79704628","display_name":"Neurology","issn_l":"0028-3878","issn":["0028-3878","1526-632X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"journal-article"},{"id":"pmid:10496277","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10496277","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1551910894","https://openalex.org/W1592698849","https://openalex.org/W1809106246","https://openalex.org/W1994599070","https://openalex.org/W2102958109","https://openalex.org/W2114243513","https://openalex.org/W2147997150","https://openalex.org/W2438506836"],"related_works":["https://openalex.org/W2417114004","https://openalex.org/W6990818042","https://openalex.org/W2544141659","https://openalex.org/W6885068664","https://openalex.org/W4312718400","https://openalex.org/W6927467459","https://openalex.org/W2042587660","https://openalex.org/W2961585674","https://openalex.org/W1966216369","https://openalex.org/W2160370499"],"abstract_inverted_index":{"Background":[0],"and":[1,36,48,102,114,136,161,182,210,219,257,273,363,366,379,389,397,427,441,460],"objectives":[2],"The":[3,52,71,107,138,232,437],"CGEP":[4,55,402,510,520,539,793],"(French":[5,31],"acronym":[6],"for":[7,34,40,123,133,201,242,282,284,302,321,338,354],"the":[8,64,99,144,152,164,243,253,276,303,322,326,339,398,406,425,469,478,482,485],"College":[9],"of":[10,13,54,66,112,116,143,149,166,174,184,213,226,299,329,342,416,431,439,471,484],"General":[11],"Practitioners":[12],"East":[14],"Paris)":[15],"is":[16,56,73,350,359,374,418],"an":[17,110,450],"independent":[18],"association":[19,494],"with":[20,103,151,224,266],"no":[21,147,375,381],"funding":[22],"from":[23,295,317,334],"industry":[24],"which":[25],"has":[26],"been":[27],"certified":[28],"by":[29,60,98,118,269,275,395,421,428],"HAS":[30,396,971],"National":[32],"Authority":[33],"Health)":[35],"CNFMC":[37],"(National":[38],"Councils":[39],"Continuous":[41],"Medical":[42],"Education).":[43],"Its":[44],"members":[45],"are":[46,171,369,387],"private":[47],"salaried":[49],"general":[50,167],"practitioners.":[51],"objective":[53],"to":[57,158,191,207,237,297,319,336,344,404,454,465,476],"improve":[58],"health":[59,153,175,443,463],"improving":[61],"care":[62,154],"through":[63,177],"use":[65,328],"good":[67],"practice":[68,75,82,113,202,216,223,241,376],"indicators":[69,233],"(GPI).":[70],"focus":[72],"on":[74,81,120,198,325],"improvement":[76,377],"(the":[77,86],"aim)":[78],"rather":[79],"than":[80],"assessment":[83],"per":[84],"se":[85,571,694],"tool).":[87],"Programme":[88,560],"This":[89],"was":[90,255,260],"a":[91,189,261,279,306,351,410,540,563,715],"3-year":[92],"programme":[93,108,562,621,950,984,1037],"initiated":[94],"in":[95,240,433,468,474],"2007,":[96],"run":[97],"association9s":[100],"committee,":[101],"29":[104,576],"participating":[105],"GPs.":[106],"involves":[109],"analysis":[111,181],"sharing":[115,183],"experience":[117,185],"GPs":[119,432],"chosen":[121],"GPIs":[122,368,386],"common":[124,472],"diseases":[125,473],"(in":[126],"particular":[127],"iatrogenic":[128],"disease,":[129],"sleep":[130],"disturbances,":[131],"orders":[132,283],"tests,":[134,285],"diabetes,":[135,286],"hypertension).":[137],"GPI":[139,304,323,340],"criteria":[140,170],"were":[141,205,234],"reliability":[142],"recommendations":[145,268],"(ie,":[146],"conflict":[148],"interest":[150],"industry),":[155],"their":[156,214,222,227],"relevance":[157],"professional":[159],"practice,":[160],"feasibility":[162],"within":[163],"scope":[165,415],"practice.":[168],"These":[169],"potential":[172],"guarantors":[173],"improvements":[176],"guideline":[178,267],"implementation.":[179],"Practice":[180],"occurred":[186],"twice":[187],"at":[188,229,481],"6":[190,700],"12":[192,702],"months":[193],"interval.":[194],"Participants":[195],"received":[196],"guides":[197],"each":[199],"indicator":[200],"analysis.":[203],"They":[204],"able":[206],"make":[208],"qualitative":[209],"quantitative":[211],"comparisons":[212],"own":[215],"over":[217],"time":[218],"also":[220,235],"compare":[221],"that":[225,252],"peers":[228],"different":[230],"times.":[231],"used":[236],"measure":[238],"trends":[239],"whole":[244,280],"group.":[245],"Results":[246],"No":[247],"participant":[248],"dropped":[249],"out":[250],"suggesting":[251],"initiative":[254,408],"relevant":[256],"feasible.":[258],"There":[259],"positive":[262,827],"trend":[263],"towards":[264],"compliance":[265,292,349],"almost":[270],"all":[271],"participants":[272,705,722,837],"especially":[274],"group":[277,291],"as":[278],"(eg,":[281],"child":[287],"obesity).":[288],"For":[289],"example,":[290],"showed":[293],"increases:":[294],"37%":[296,335,876,922],"86%":[298,883],"patient":[300,479,1062],"files":[301],"\u2018no":[305],"non":[307,557,819,991],"steroidal":[308],"anti-inflammatory":[309],"drug":[310],"during":[311,315],"pregnancy\u2019":[312],"(iatrogenic":[313],"disease":[314],"pregnancy);":[316],"33%":[318,899],"79%":[320,901],"\u2018advice":[324],"correct":[327],"condoms\u2019":[330],"(sexually":[331],"transmitted":[332],"infections);":[333],"56%":[337,924],"\u2018prescription":[341],"alternatives":[343,914],"benzodiazepines\u2019":[345],"(sleep":[346],"disturbances).":[347],"Although":[348],"surrogate":[352],"endpoint":[353],"determining":[355],"clinical":[356,383],"impact,":[357],"it":[358],"nevertheless":[360],"essential.":[361,370],"Discussion":[362,932],"conclusion":[364],"Relevant":[365],"reliable":[367],"Without":[371],"them,":[372],"there":[373],"plan":[378,453],"consequently":[380],"managed":[382],"improvement.":[384],"However,":[385],"few":[388],"far":[390],"between":[391],"despite":[392],"work":[393],"done":[394],"first-rate":[399],"journal":[400],"Prescrire.":[401],"plans":[403],"turn":[405],"present":[407],"into":[409],"permanent":[411,989],"project":[412],"but":[413],"its":[414],"action":[417],"seriously":[419],"hampered":[420],"administrative":[422],"\u2018beating":[423],"about":[424],"bush\u2019":[426],"mandatory":[429],"participation":[430,438,1016],"various":[434],"schemes":[435],"(CME/PPA/CDP).":[436],"specialists":[440],"allied":[442,462],"professionals,":[444],"besides":[445],"GPs,":[446],"would":[447],"probably":[448],"be":[449],"asset.":[451],"We":[452],"invite":[455],"interested":[456],"specialists,":[457],"pharmacists,":[458],"nurses":[459],"other":[461],"professionals":[464],"join":[466],"us":[467],"management":[470],"order":[475],"put":[477],"back":[480],"centre":[483,1064],"action.":[486,1067],"Le":[487,509,538,620,983],"Coll\u00e8ge":[488],"des":[489,512,528,532,545,602,635,663,692,707,711,765,777,798,831,836,896],"G\u00e9n\u00e9ralistes":[490],"de":[491,498,523,534,590,597,631,637,649,654,669,673,680,682,684,699,719,730,740,746,756,785,789,809,833,862,875,878,880,884,898,903,921,925,934,940,949,969,973,1000,1017,1020,1022,1048,1059,1065],"l9Est":[492],"Parisien,":[493],"1901":[495],"strictement":[496],"ind\u00e9pendante":[497],"tout":[499],"financement":[500],"industriel,":[501],"est":[502,521,622,761,801,873,919,985,1041],"un":[503,554,595,802,1004,1033],"organisme":[504],"agr\u00e9\u00e9":[505],"(HAS":[506],"et":[507,516,556,580,690,726,734,788,838,946,952,962,972,990,1019,1055],"CNFMC).":[508],"regroupe":[511],"m\u00e9decins":[513,1028],"g\u00e9n\u00e9ralistes":[514,578,1029],"lib\u00e9raux":[515,579],"salari\u00e9s.":[517],"L9objectif":[518],"du":[519,613,629,759,840,911,1009,1013],"l9am\u00e9lioration":[522,527,681,796],"la":[524,591,655,661,685,757,834,857,863,869,906,970,974,1001],"sant\u00e9":[525,683],"par":[526,626,641],"soins":[529],"reposant":[530],"sur":[531,573,587,713],"indicateurs":[533,603,636,712,766],"bonne":[535,638,935],"pratique":[536,592,639,662,733,737,758],"(IBP).":[537],"pr\u00e9f\u00e9r\u00e9":[541],"le":[542,642,667,792,829,871,917,938,958,1061],"terme":[543,550],"d9Am\u00e9lioration":[544],"pratiques":[546,598,693,799],"professionnelles":[547,800],"(APP)":[548],"au":[549,779,860,1063],"d9EPP":[551],"qui":[552],"constitue":[553],"outil":[555],"une":[558,588,751,775,825],"finalit\u00e9.":[559],"Ce":[561],"\u00e9t\u00e9":[564],"mis":[565,623],"en":[566,568,624,676,678,687,928],"place":[567],"2007.":[569],"Il":[570,585,748],"d\u00e9roule":[572],"3":[574],"ans.":[575],"professionnels,":[577],"salari\u00e9s,":[581],"y":[582],"sont":[583,771,821],"inscrits.":[584],"repose":[586],"analyse":[589,718],"coupl\u00e9e":[593],"\u00e0":[594,660,701,738,743,763,882,900,923,1007],"\u00e9change":[596],"entre":[599],"professionnels":[600,1021],"concernant":[601,709,997],"choisis":[604],"dans":[605,828,842,908],"les":[606,627,815,890,909,967,1026,1043],"pathologies":[607,1049],"fr\u00e9quentes":[608],"(notamment":[609],"Pathologies":[610],"iatrog\u00e8nes,":[611],"Troubles":[612],"sommeil,":[614],"Prescription":[615],"d9examens":[616,849],"compl\u00e9mentaires,":[617],"Diab\u00e8te,":[618],"HTA).":[619],"\u0153uvre":[625,677],"membres":[628],"bureau":[630],"l9association.":[632],"Les":[633,704,721,769,994],"crit\u00e8res":[634],"s\u00e9lectionn\u00e9s":[640],"groupe":[643,760,841,872,918],"EPP-CGEP":[644],"sont:":[645],"fiabilit\u00e9":[646],"(recommandations":[647],"indemnes":[648],"conflits":[650],"d9int\u00e9r\u00eats":[651],"avec":[652,887,930],"l9industrie":[653],"sant\u00e9),":[656],"pertinence":[657,787],"(par":[658],"rapport":[659],"professionnels),":[664],"faisabilit\u00e9":[665,791],"(dans":[666],"cadre":[668],"l9exercice":[670],"professionnel),":[671],"garantes":[672],"leur":[674,717,731,736],"mise":[675],"vue":[679],"population":[686],"charge.":[688],"L9analyse":[689],"l9\u00e9change":[691],"fait":[695],"2":[696],"fois,":[697],"espac\u00e9es":[698],"mois.":[703],"re\u00e7oivent":[706],"\u2018aide-m\u00e9moire\u2019":[708],"chacun":[710],"lesquels":[714],"port\u00e9":[716],"pratique.":[720],"peuvent":[723],"ainsi,":[724],"qualitativement":[725],"quantitativement,":[727],"comparer":[728,735],"l9\u00e9volution":[729,754],"propre":[732],"celle":[739],"leurs":[741],"pairs":[742],"plusieurs":[744],"mois":[745],"distance.":[747],"existe":[749],"enfin":[750],"dimension":[752],"collective:":[753],"globale":[755],"mesur\u00e9e":[762],"l9aune":[764],"choisis.":[767],"R\u00e9sultats":[768],"r\u00e9sultats":[770],"positifs.":[772],"Nous":[773,823],"constatons:":[774],"adh\u00e9sion":[776],"inscrits":[778],"projet,":[780],"sans":[781,1031],"d\u00e9fection,":[782],"rendant":[783],"compte":[784],"sa":[786,790],"estime":[794],"que":[795,818,1025,1052],"objectiv\u00e9e":[797],"crit\u00e8re":[803],"certes":[804],"interm\u00e9diaire":[805],"mais":[806],"essentiel":[807],"d9am\u00e9lioration":[808,954],"l9impact":[810],"clinique.":[811],"A":[812],"ce":[813],"titre,":[814],"r\u00e9sultats,":[816],"bien":[817],"homog\u00e8nes,":[820],"encourageants.":[822],"constatons":[824],"\u00e9volution":[826],"sens":[830],"recommandations,":[832],"quasi-totalit\u00e9":[835],"surtout":[839],"son":[843],"ensemble.":[844],"Quelques":[845],"exemples":[846],"(outre":[847],"prescription":[848,907],"compl\u00e9mentaires":[850],"ou":[851,853],"diab\u00e8te":[852],"ob\u00e9sit\u00e9":[854],"infantile):":[855],"pour":[856,889,905,987,1035],"pathologie":[858],"iatrog\u00e8ne":[859],"cours":[861],"grossesse":[864],"(Indicateur:":[865,892],"pas":[866,948,953,992],"d9AINS":[867],"durant":[868],"grossesse)":[870],"pass\u00e9":[874,920],"seulement":[877],"d\u00e9marches":[879,926],"BP":[881],"dossiers":[885],"concordants":[886],"l9IBP.":[888,931],"InfectionsSexuellementTransmissibles":[891],"conseils":[893],"d9utilisation":[894],"correcte":[895],"pr\u00e9servatifs)":[897],"d9application":[902],"BP.":[904],"troubles":[910],"sommeil":[912],"(IBP:":[913],"aux":[915],"BZD)":[916],"cliniques":[927],"accord":[929],"Indicateurs":[933],"pratique:":[936],"c9est":[937],"socle":[939],"notre":[941,1036,1066],"action:":[942],"Sans":[943],"IBP":[944],"pertinents":[945,963],"fiables,":[947],"d9APP":[951],"clinique":[955],"organis\u00e9e.":[956],"Or,":[957],"nombre":[959],"d9indicateurs":[960],"valides":[961],"reste":[964],"insuffisant":[965],"malgr\u00e9":[966],"travaux":[968],"revue":[975],"Prescrire":[976],"dont":[977],"nous":[978],"sommes":[979],"proches.":[980],"Action":[981],"continue:":[982],"pr\u00e9vu":[986],"devenir":[988],"ponctuel.":[993],"tergiversations":[995],"administratives":[996],"l9obligation":[998],"effective":[999],"FMC/EPP/DPC":[1002],"constituent":[1003],"frein":[1005],"notable":[1006],"l9action":[1008],"CGEP.":[1010],"Polydisciplinarit\u00e9":[1011],"autour":[1012,1047],"patient.":[1014],"La":[1015],"sp\u00e9cialistes":[1018],"sant\u00e9,":[1023],"autres":[1024,1044,1056],"seuls":[1027],"serait":[1030],"doute":[1032],"plus":[1034],"d9APP.":[1038],"Notre":[1039],"projet":[1040],"d9int\u00e9grer":[1042],"sp\u00e9cialit\u00e9s":[1045],"int\u00e9ress\u00e9es,":[1046],"fr\u00e9quentes,":[1050],"ainsi":[1051],"pharmaciens,":[1053],"infirmi\u00e8res":[1054],"param\u00e9dicaux,":[1057],"afin":[1058],"replacer":[1060]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}