{"id":"https://openalex.org/W2004453547","doi":"https://doi.org/10.1007/s11030-009-9151-y","title":"New tetracyclic tetrahydro-\u03b2-carbolines as tryptophan-derived peptidomimetics","display_name":"New tetracyclic tetrahydro-\u03b2-carbolines as tryptophan-derived peptidomimetics","publication_year":2009,"publication_date":"2009-06-15","ids":{"openalex":"https://openalex.org/W2004453547","doi":"https://doi.org/10.1007/s11030-009-9151-y","mag":"2004453547","pmid":"https://pubmed.ncbi.nlm.nih.gov/19529982"},"language":"en","primary_location":{"id":"doi:10.1007/s11030-009-9151-y","doi":"https://doi.org/10.1007/s11030-009-9151-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11030-009-9151-y","pdf_url":null,"source":{"id":"https://openalex.org/S105791650","display_name":"Molecular Diversity","issn_l":"1381-1991","issn":["1381-1991","1573-501X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Diversity","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033534347","display_name":"Karolina Pulka\u2010Ziach","orcid":"https://orcid.org/0000-0002-2861-1466","observed_orcids":["https://orcid.org/0000-0002-2861-1466"]},"institutions":[{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Karolina Pulka","raw_affiliation_strings":["Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. karola@chem.uw.edu.pl","University of Warsaw"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. karola@chem.uw.edu.pl","institution_ids":["https://openalex.org/I4654613"]},{"raw_affiliation_string":"University of Warsaw","institution_ids":["https://openalex.org/I4654613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059081351","display_name":"Debby Feytens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Debby Feytens","raw_affiliation_strings":["Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium","Vrije Universiteit Brussel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"Vrije Universiteit Brussel","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037449952","display_name":"Aleksandra Misicka","orcid":"https://orcid.org/0000-0001-7446-2396","observed_orcids":["https://orcid.org/0000-0001-7446-2396"]},"institutions":[{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Aleksandra Misicka","raw_affiliation_strings":["Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland","Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02-106, Warsaw, Poland","Polish Academy of Sciences","University of Warsaw"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland","institution_ids":["https://openalex.org/I4654613"]},{"raw_affiliation_string":"Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02-106, Warsaw, Poland","institution_ids":["https://openalex.org/I99542240"]},{"raw_affiliation_string":"Polish Academy of Sciences","institution_ids":["https://openalex.org/I99542240"]},{"raw_affiliation_string":"University of Warsaw","institution_ids":["https://openalex.org/I4654613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064093167","display_name":"Dirk Tourw\u00e9","orcid":"https://orcid.org/0000-0002-2329-0798","observed_orcids":["https://orcid.org/0000-0002-2329-0798"]},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Dirk Tourw\u00e9","raw_affiliation_strings":["Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium","Vrije Universiteit Brussel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"Vrije Universiteit Brussel","institution_ids":["https://openalex.org/I13469542"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033534347","https://openalex.org/A5064093167"],"corresponding_institution_ids":["https://openalex.org/I13469542","https://openalex.org/I4654613"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":null,"fwci":0.6011,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.61091546,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"14","issue":"1","first_page":"97","last_page":"108"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13188","display_name":"Synthesis and bioactivity of alkaloids","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13188","display_name":"Synthesis and bioactivity of alkaloids","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12973","display_name":"Synthesis of Indole Derivatives","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pictet-spengler-reaction","display_name":"Pictet-Spengler reaction","score":0.9900000095367432},{"id":"https://openalex.org/keywords/heterocyclic-cyclization","display_name":"heterocyclic cyclization","score":0.8730000257492065},{"id":"https://openalex.org/keywords/peptidomimetics","display_name":"peptidomimetics","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C124790011","wikidata":"https://www.wikidata.org/wiki/Q2069797","display_name":"Peptidomimetic","level":3,"score":0.9180353283882141},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.7671247124671936},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7641916275024414},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5857515335083008},{"id":"https://openalex.org/C204921945","wikidata":"https://www.wikidata.org/wiki/Q899689","display_name":"Side chain","level":3,"score":0.5720120072364807},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.4470500648021698},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4251856207847595},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3308963179588318},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.29868772625923157},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10024222731590271},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002243","descriptor_name":"Carbolines","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D002243","descriptor_name":"Carbolines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D048289","descriptor_name":"Imidazolidines","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D048289","descriptor_name":"Imidazolidines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11030-009-9151-y","doi":"https://doi.org/10.1007/s11030-009-9151-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11030-009-9151-y","pdf_url":null,"source":{"id":"https://openalex.org/S105791650","display_name":"Molecular Diversity","issn_l":"1381-1991","issn":["1381-1991","1573-501X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Diversity","raw_type":"journal-article"},{"id":"pmid:19529982","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19529982","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular diversity","raw_type":"Journal Article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:68800","doi":null,"is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/new-tetracyclic-tetrahydrobetacarbolines-as-tryptophanderived-peptidomimetics(bdc5701d-2389-4260-ad8e-00ecda7b00d1).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323873","display_name":"Uniwersytet Warszawski","ror":"https://ror.org/039bjqg32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1969278485","https://openalex.org/W1974916883","https://openalex.org/W1977357075","https://openalex.org/W1978705163","https://openalex.org/W1983245237","https://openalex.org/W1996196279","https://openalex.org/W2003641169","https://openalex.org/W2003927082","https://openalex.org/W2007172166","https://openalex.org/W2017505146","https://openalex.org/W2021005940","https://openalex.org/W2022290382","https://openalex.org/W2025489019","https://openalex.org/W2030953755","https://openalex.org/W2047029005","https://openalex.org/W2047730466","https://openalex.org/W2057491831","https://openalex.org/W2058668626","https://openalex.org/W2068937181","https://openalex.org/W2070259701","https://openalex.org/W2071579644","https://openalex.org/W2072677818","https://openalex.org/W2077187202","https://openalex.org/W2082189667","https://openalex.org/W2086244857","https://openalex.org/W2092408053","https://openalex.org/W2102401508","https://openalex.org/W2111917331","https://openalex.org/W2126896985","https://openalex.org/W2131124255","https://openalex.org/W2296797928","https://openalex.org/W2408914305","https://openalex.org/W2949097810","https://openalex.org/W2949131629","https://openalex.org/W2950175214","https://openalex.org/W2952355883","https://openalex.org/W2952804833"],"related_works":["https://openalex.org/W2002596407","https://openalex.org/W2178302278","https://openalex.org/W2408914305","https://openalex.org/W2300931628","https://openalex.org/W7221192974","https://openalex.org/W2020258238","https://openalex.org/W7074195213","https://openalex.org/W1999521576","https://openalex.org/W2060460016","https://openalex.org/W4417477140"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}