{"id":"https://openalex.org/W2004451402","doi":"https://doi.org/10.1097/00000478-198101000-00008","title":"Sarcomas of bone complicating osteitis deformans (Paget\u02bcs disease)","display_name":"Sarcomas of bone complicating osteitis deformans (Paget\u02bcs disease)","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W2004451402","doi":"https://doi.org/10.1097/00000478-198101000-00008","mag":"2004451402","pmid":"https://pubmed.ncbi.nlm.nih.gov/6941703"},"language":"en","primary_location":{"id":"doi:10.1097/00000478-198101000-00008","doi":"https://doi.org/10.1097/00000478-198101000-00008","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000478-198101000-00008","pdf_url":null,"source":{"id":"https://openalex.org/S37879208","display_name":"The American Journal of Surgical Pathology","issn_l":"0147-5185","issn":["0147-5185","1532-0979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055065582","display_name":"Mark Robert Wick","orcid":"https://orcid.org/0000-0002-6803-144X","observed_orcids":["https://orcid.org/0000-0002-6803-144X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark R. Wick","raw_affiliation_strings":["Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109918177","display_name":"Richard A. McLeod","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard A. McLeod","raw_affiliation_strings":["Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017208495","display_name":"Gene P. Siegal","orcid":"https://orcid.org/0000-0003-3857-3368","observed_orcids":["https://orcid.org/0000-0003-3857-3368"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gene P. Siegal","raw_affiliation_strings":["Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036760834","display_name":"Harry G. Greditzer","orcid":"https://orcid.org/0000-0002-6161-5426","observed_orcids":["https://orcid.org/0000-0002-6161-5426"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry G. Greditzer","raw_affiliation_strings":["Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113654214","display_name":"K. Krishnan Unni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Krishnan K. Unni","raw_affiliation_strings":["Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgical Pathology, Mayo Clinic, Rochester, Minnesota 55901","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":null,"apc_paid":null,"fwci":5.5616,"has_fulltext":false,"cited_by_count":182,"citation_normalized_percentile":{"value":0.95076122,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"5","issue":"1","first_page":"47","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.0681999996304512,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paget-s-disease-of-bone","display_name":"Paget's disease of bone","score":0.9789999723434448},{"id":"https://openalex.org/keywords/bone-sarcoma","display_name":"bone sarcoma","score":0.8410000205039978},{"id":"https://openalex.org/keywords/osteosarcoma","display_name":"osteosarcoma","score":0.8669999837875366},{"id":"https://openalex.org/keywords/fibrosarcoma","display_name":"fibrosarcoma","score":0.9890000224113464},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.8119999766349792},{"id":"https://openalex.org/keywords/sarcomatous-change","display_name":"sarcomatous change","score":0.7570000290870667},{"id":"https://openalex.org/keywords/pelvic-bone-tumors","display_name":"pelvic bone tumors","score":0.5839999914169312},{"id":"https://openalex.org/keywords/humerus","display_name":"humerus","score":0.6690000295639038},{"id":"https://openalex.org/keywords/femur","display_name":"femur","score":0.9909999966621399},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.49399998784065247},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.890999972820282},{"id":"https://openalex.org/keywords/local-tumor-spread","display_name":"local tumor extension","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9279474020004272},{"id":"https://openalex.org/C2909112397","wikidata":"https://www.wikidata.org/wiki/Q2035074","display_name":"Osteitis Deformans","level":4,"score":0.6871660351753235},{"id":"https://openalex.org/C2781343496","wikidata":"https://www.wikidata.org/wiki/Q1178507","display_name":"Osteitis","level":3,"score":0.6243259310722351},{"id":"https://openalex.org/C2776206872","wikidata":"https://www.wikidata.org/wiki/Q162595","display_name":"Humerus","level":2,"score":0.5007791519165039},{"id":"https://openalex.org/C2778357063","wikidata":"https://www.wikidata.org/wiki/Q713102","display_name":"Pelvis","level":2,"score":0.499096155166626},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.4750882685184479},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.46898800134658813},{"id":"https://openalex.org/C2780554211","wikidata":"https://www.wikidata.org/wiki/Q176503","display_name":"Femur","level":2,"score":0.46742576360702515},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4565458297729492},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.44541221857070923},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4372240900993347},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4322251081466675},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.39222681522369385},{"id":"https://openalex.org/C2776154862","wikidata":"https://www.wikidata.org/wiki/Q2035074","display_name":"Paget's disease of bone","level":3,"score":0.3912387490272522},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.30428367853164673},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.17797696590423584},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17292794585227966},{"id":"https://openalex.org/C2780551157","wikidata":"https://www.wikidata.org/wiki/Q938983","display_name":"Osteomyelitis","level":2,"score":0.16188758611679077},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001859","descriptor_name":"Bone Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010001","descriptor_name":"Osteitis Deformans","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010001","descriptor_name":"Osteitis Deformans","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010001","descriptor_name":"Osteitis Deformans","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/00000478-198101000-00008","doi":"https://doi.org/10.1097/00000478-198101000-00008","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00000478-198101000-00008","pdf_url":null,"source":{"id":"https://openalex.org/S37879208","display_name":"The American Journal of Surgical Pathology","issn_l":"0147-5185","issn":["0147-5185","1532-0979"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Surgical Pathology","raw_type":"journal-article"},{"id":"pmid:6941703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6941703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of surgical pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8799999952316284,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2089800656","https://openalex.org/W1863433568","https://openalex.org/W2039487093","https://openalex.org/W2106466477","https://openalex.org/W2078431616","https://openalex.org/W2065914064","https://openalex.org/W2046296857","https://openalex.org/W2045754602","https://openalex.org/W2143561401","https://openalex.org/W3101047001"],"abstract_inverted_index":{"Osteitis":[0],"deformans":[1],"(Paget's":[2],"disease":[3],"of":[4,29,32,36,54,62,79,82,98,107,115],"bone)":[5],"may":[6],"be":[7,130],"complicated":[8],"by":[9],"osseous":[10],"cancer.":[11],"Of":[12,67],"3964":[13],"patients":[14,119,139],"between":[15],"1927":[16],"and":[17,45,65,74],"1977,":[18],"38":[19,69],"had":[20],"primary":[21],"malignant":[22],"bone":[23],"tumors.":[24],"This":[25],"represents":[26],"an":[27],"incidence":[28],"sarcomatous":[30],"change":[31],"0.95%.":[33],"The":[34,88,104],"bones":[35],"the":[37,43,46,55,60,63,68,80,84,137,141],"pelvis":[38],"were":[39,48,72,76,120],"most":[40],"often":[41],"involved;":[42],"humerus":[44],"femur":[47],"next":[49],"in":[50,140],"frequency.":[51],"No":[52],"region":[53],"skeleton":[56],"was":[57,92,109],"spared,":[58],"with":[59,94],"exception":[61],"forearms":[64],"hands.":[66],"tumors,":[70],"six":[71],"fibrosarcomas":[73],"32":[75],"osteosarcomas.":[77],"Irrespective":[78],"site":[81],"involvement,":[83],"histopathologic":[85],"extremely":[86],"poor.":[87],"5-year":[89],"survival":[90],"rate":[91,97],"7.9%,":[93],"a":[95],"mortality":[96],"86.8%":[99],"36":[100],"months":[101],"after":[102],"diagnosis.":[103],"main":[105],"cause":[106],"death":[108],"pulmonary":[110],"metastasis":[111],"or":[112,126],"local":[113],"extension":[114],"tumor":[116],"growth.":[117],"Three":[118],"long-term":[121],"survivors,":[122],"but":[123],"no":[124],"clinical":[125],"pathologic":[127],"elements":[128],"could":[129],"identified":[131],"which":[132],"differentiated":[133],"these":[134],"survivors":[135],"from":[136],"other":[138],"study.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}