{"id":"https://openalex.org/W2004347582","doi":"https://doi.org/10.1016/s0006-8993(01)03323-6","title":"cGMP-induced presynaptic depression and postsynaptic facilitation at glutamatergic synapses in visual cortex","display_name":"cGMP-induced presynaptic depression and postsynaptic facilitation at glutamatergic synapses in visual cortex","publication_year":2002,"publication_date":"2002-02-01","ids":{"openalex":"https://openalex.org/W2004347582","doi":"https://doi.org/10.1016/s0006-8993(01)03323-6","mag":"2004347582","pmid":"https://pubmed.ncbi.nlm.nih.gov/11814431"},"language":"en","primary_location":{"id":"doi:10.1016/s0006-8993(01)03323-6","doi":"https://doi.org/10.1016/s0006-8993(01)03323-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(01)03323-6","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108353621","display_name":"Ji-Ye Wei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ji-Ye Wei","raw_affiliation_strings":["Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111774426","display_name":"Xiao\u2010Tao Jin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaotao Jin","raw_affiliation_strings":["Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085203223","display_name":"Ethan David Cohen","orcid":"https://orcid.org/0000-0001-6365-2266","observed_orcids":["https://orcid.org/0000-0001-6365-2266"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ethan D. Cohen","raw_affiliation_strings":["Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109250727","display_name":"Nigel W. Daw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nigel W. Daw","raw_affiliation_strings":["Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001481519","display_name":"Colin James Barnstable","orcid":"https://orcid.org/0000-0002-7011-4068","observed_orcids":["https://orcid.org/0000-0002-7011-4068"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Colin J. Barnstable","raw_affiliation_strings":["Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology and Visual Science, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208061, New Haven, CT 06520-8061, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001481519"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":1.0456,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.70628661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"927","issue":"1","first_page":"42","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cgmp","display_name":"cyclic GMP","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cgmp-dependent-protein-kinase","display_name":"cGMP-dependent protein kinase","score":0.9760000109672546},{"id":"https://openalex.org/keywords/presynaptic-depression","display_name":"presynaptic depression","score":0.9800000190734863},{"id":"https://openalex.org/keywords/glutamatergic-synapses","display_name":"glutamatergic synapses","score":0.9850000143051147},{"id":"https://openalex.org/keywords/visual-cortex","display_name":"visual cortex","score":0.9950000047683716},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potentials","display_name":"excitatory postsynaptic potentials","score":0.7820000052452087},{"id":"https://openalex.org/keywords/spontaneous-epscs","display_name":"spontaneous EPSCs","score":0.7889999747276306},{"id":"https://openalex.org/keywords/calcium-current","display_name":"calcium current","score":0.8379999995231628},{"id":"https://openalex.org/keywords/synaptic-transmission-modulation","display_name":"synaptic transmission modulation","score":0.6919999718666077},{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"neuroplasticity","score":0.699999988079071}],"concepts":[{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7774806022644043},{"id":"https://openalex.org/C189184402","wikidata":"https://www.wikidata.org/wiki/Q3454536","display_name":"Kainate receptor","level":5,"score":0.7203947305679321},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.7023624181747437},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.6562865972518921},{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.6185525059700012},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.5758023262023926},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5600000619888306},{"id":"https://openalex.org/C2780648746","wikidata":"https://www.wikidata.org/wiki/Q28208871","display_name":"Glutamatergic","level":4,"score":0.5381499528884888},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.48101693391799927},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.46932452917099},{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.46436095237731934},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4319784641265869},{"id":"https://openalex.org/C2910581834","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Postsynaptic Current","level":4,"score":0.4249061942100525},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41844603419303894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37821125984191895},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14434733986854553},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11801379919052124}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006152","descriptor_name":"Cyclic GMP","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D006152","descriptor_name":"Cyclic GMP","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009433","descriptor_name":"Neural Inhibition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009842","descriptor_name":"Oligopeptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015220","descriptor_name":"Calcium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017729","descriptor_name":"Presynaptic Terminals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017869","descriptor_name":"Cyclic GMP-Dependent Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018408","descriptor_name":"Patch-Clamp Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018690","descriptor_name":"Excitatory Amino Acid Agonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019706","descriptor_name":"Excitatory Postsynaptic Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0006-8993(01)03323-6","doi":"https://doi.org/10.1016/s0006-8993(01)03323-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0006-8993(01)03323-6","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:11814431","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11814431","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.5,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2202698264","display_name":null,"funder_award_id":"EY-11353","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G2746858311","display_name":"Molecular Determinants of Visual Cortical Plasticity","funder_award_id":"5r01ey011356-06","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3037146770","display_name":null,"funder_award_id":"EY10617","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G4937087079","display_name":"ANALYSIS OF VISUAL MICROCIRCUITS","funder_award_id":"5r01ey010617-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5482838575","display_name":"FUNCTION OF GLUTAMATE RECEPTORS IN VISUAL CORTEX","funder_award_id":"5r01ey011353-07","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6661595526","display_name":"Yale Core Grant For Vision Research","funder_award_id":"P30EY000785","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G746631196","display_name":null,"funder_award_id":"EY-00785","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G7935098529","display_name":null,"funder_award_id":"EY11356","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W401627714","https://openalex.org/W639366727","https://openalex.org/W1040659669","https://openalex.org/W1502426712","https://openalex.org/W1532214820","https://openalex.org/W1533926750","https://openalex.org/W1584397225","https://openalex.org/W1588361932","https://openalex.org/W1597810581","https://openalex.org/W1661090471","https://openalex.org/W1662420266","https://openalex.org/W1800713457","https://openalex.org/W1964403867","https://openalex.org/W1965477172","https://openalex.org/W1967380684","https://openalex.org/W1968430518","https://openalex.org/W1970706135","https://openalex.org/W1970818563","https://openalex.org/W1972392931","https://openalex.org/W1976262809","https://openalex.org/W1977223788","https://openalex.org/W1978411339","https://openalex.org/W1981515471","https://openalex.org/W1983547991","https://openalex.org/W1988189113","https://openalex.org/W1996698215","https://openalex.org/W2000424850","https://openalex.org/W2002031220","https://openalex.org/W2003861265","https://openalex.org/W2010403508","https://openalex.org/W2012275274","https://openalex.org/W2014316556","https://openalex.org/W2016008761","https://openalex.org/W2026655554","https://openalex.org/W2034510219","https://openalex.org/W2035584685","https://openalex.org/W2039547724","https://openalex.org/W2040470787","https://openalex.org/W2053731784","https://openalex.org/W2056020805","https://openalex.org/W2059003940","https://openalex.org/W2065388112","https://openalex.org/W2074667754","https://openalex.org/W2075360793","https://openalex.org/W2087758815","https://openalex.org/W2087848337","https://openalex.org/W2099834228","https://openalex.org/W2108999152","https://openalex.org/W2112058830","https://openalex.org/W2118969839","https://openalex.org/W2124333932","https://openalex.org/W2127265774","https://openalex.org/W2135718268","https://openalex.org/W2143046795","https://openalex.org/W2148342376","https://openalex.org/W2166777688","https://openalex.org/W2169280213","https://openalex.org/W2172527495","https://openalex.org/W2236009233","https://openalex.org/W2400699314","https://openalex.org/W2465320047","https://openalex.org/W2485688483"],"related_works":["https://openalex.org/W1995190911","https://openalex.org/W1597810581","https://openalex.org/W2094899105","https://openalex.org/W1972392931","https://openalex.org/W2958478601","https://openalex.org/W1824502655","https://openalex.org/W7163186293","https://openalex.org/W2102386138","https://openalex.org/W1977223788","https://openalex.org/W1661090471"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}