{"id":"https://openalex.org/W2004336149","doi":"https://doi.org/10.1016/0005-2736(85)90296-2","title":"Abnormal transbilayer mobility of phosphatidylcholine in hereditary pyropoikilocytosis reflects the increased heat sensitivity of the membrane skeleton","display_name":"Abnormal transbilayer mobility of phosphatidylcholine in hereditary pyropoikilocytosis reflects the increased heat sensitivity of the membrane skeleton","publication_year":1985,"publication_date":"1985-05-01","ids":{"openalex":"https://openalex.org/W2004336149","doi":"https://doi.org/10.1016/0005-2736(85)90296-2","mag":"2004336149","pmid":"https://pubmed.ncbi.nlm.nih.gov/3995028"},"language":"en","primary_location":{"id":"doi:10.1016/0005-2736(85)90296-2","doi":"https://doi.org/10.1016/0005-2736(85)90296-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0005-2736(85)90296-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210187475","display_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","issn_l":"0005-2736","issn":["0005-2736","1879-2642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075636203","display_name":"Paul Franck","orcid":"https://orcid.org/0000-0002-0157-2022","observed_orcids":["https://orcid.org/0000-0002-0157-2022"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P.F.H. Franck","raw_affiliation_strings":["Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109032210","display_name":"Jos A.F. Op den Kamp","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J.A.F. Op den Kamp","raw_affiliation_strings":["Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108348524","display_name":"Bertram H. Lubin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Lubin","raw_affiliation_strings":["Bruce Lyon Memorial Research Laboratory and Department of Hematology/ Oncology, Children's Hospital Medical Center of Northern California, Oakland, CA 94609 U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bruce Lyon Memorial Research Laboratory and Department of Hematology/ Oncology, Children's Hospital Medical Center of Northern California, Oakland, CA 94609 U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051056909","display_name":"Wim Berendsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"W. Berendsen","raw_affiliation_strings":["Department of Molecular Cell Biology, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Cell Biology, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071948808","display_name":"P. Joosten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P. Joosten","raw_affiliation_strings":["Department of Hematology, University Hospital Leiden, Rijnsburgerweg 10, 2333 AA Leiden The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University Hospital Leiden, Rijnsburgerweg 10, 2333 AA Leiden The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113848878","display_name":"Ernest Bri\u00ebt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"E. Bri\u00ebt","raw_affiliation_strings":["Department of Hematology, University Hospital Leiden, Rijnsburgerweg 10, 2333 AA Leiden The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, University Hospital Leiden, Rijnsburgerweg 10, 2333 AA Leiden The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112806563","display_name":"L.L.M. Van Deenen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"L.L.M. van Deenen","raw_affiliation_strings":["Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025713708","display_name":"Ben Roelofsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"B. Roelofsen","raw_affiliation_strings":["Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, State University of Utrecht Padualaan 8, NL-3584 CH Utrecht, The Netherlands","institution_ids":["https://openalex.org/I193662353"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3870,"currency":"USD","value_usd":3870},"apc_paid":null,"fwci":1.5133,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.82557546,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"815","issue":"2","first_page":"259","last_page":"267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","score":0.227400004863739,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hereditary-pyropoikilocytosis","display_name":"hereditary pyropoikilocytosis","score":1.0},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.9660000205039978},{"id":"https://openalex.org/keywords/erythrocyte-membrane","display_name":"erythrocyte membrane","score":0.8730000257492065},{"id":"https://openalex.org/keywords/membrane-skeleton","display_name":"membrane skeleton","score":0.9190000295639038},{"id":"https://openalex.org/keywords/spectrin","display_name":"spectrin","score":0.8619999885559082},{"id":"https://openalex.org/keywords/thermal-sensitivity","display_name":"thermal sensitivity","score":0.7850000262260437},{"id":"https://openalex.org/keywords/lipid-bilayer-stability","display_name":"lipid bilayer stability","score":0.8370000123977661},{"id":"https://openalex.org/keywords/phospholipase-a2","display_name":"phospholipase A2","score":0.8320000171661377},{"id":"https://openalex.org/keywords/membrane-asymmetry","display_name":"membrane asymmetry","score":0.5249999761581421},{"id":"https://openalex.org/keywords/red-blood-cell-membrane-defects","display_name":"red blood cell membrane defects","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C18969341","wikidata":"https://www.wikidata.org/wiki/Q1169129","display_name":"Skeleton (computer programming)","level":2,"score":0.6706645488739014},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.4894498884677887},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.47619473934173584},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.4253653585910797},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39363470673561096},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33894288539886475},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2389661967754364},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2050803303718567},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11661034822463989},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09308740496635437},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.07780095934867859},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.06057402491569519},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000745","descriptor_name":"Anemia, Hemolytic, Congenital","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000745","descriptor_name":"Anemia, Hemolytic, Congenital","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004913","descriptor_name":"Erythrocytes, Abnormal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004913","descriptor_name":"Erythrocytes, Abnormal","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008560","descriptor_name":"Membrane Fluidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010713","descriptor_name":"Phosphatidylcholines","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013049","descriptor_name":"Spectrin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0005-2736(85)90296-2","doi":"https://doi.org/10.1016/0005-2736(85)90296-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0005-2736(85)90296-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210187475","display_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","issn_l":"0005-2736","issn":["0005-2736","1879-2642"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Biomembranes","raw_type":"journal-article"},{"id":"pmid:3995028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3995028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1336145280","display_name":null,"funder_award_id":"RR05467","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G84739426","display_name":null,"funder_award_id":"HL27059","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W141631069","https://openalex.org/W1486313261","https://openalex.org/W1554688619","https://openalex.org/W1582516167","https://openalex.org/W1586878603","https://openalex.org/W1608391891","https://openalex.org/W1972184105","https://openalex.org/W1973762235","https://openalex.org/W1975376384","https://openalex.org/W1981776612","https://openalex.org/W1993062631","https://openalex.org/W1997001075","https://openalex.org/W2002604567","https://openalex.org/W2003709444","https://openalex.org/W2005859080","https://openalex.org/W2023150271","https://openalex.org/W2033014359","https://openalex.org/W2035591072","https://openalex.org/W2057314484","https://openalex.org/W2062828619","https://openalex.org/W2067708770","https://openalex.org/W2075641729","https://openalex.org/W2083665434","https://openalex.org/W2088672032","https://openalex.org/W2091647374","https://openalex.org/W2103537552","https://openalex.org/W2116955854","https://openalex.org/W2157719407","https://openalex.org/W2179142653","https://openalex.org/W2186595494","https://openalex.org/W2397149717","https://openalex.org/W2412174089","https://openalex.org/W2414121199","https://openalex.org/W2414351942","https://openalex.org/W2419365886","https://openalex.org/W4236512430"],"related_works":["https://openalex.org/W1486313261","https://openalex.org/W2063810897","https://openalex.org/W1974255968","https://openalex.org/W1575458839","https://openalex.org/W961785807","https://openalex.org/W2000266304","https://openalex.org/W1608391891","https://openalex.org/W2414351942","https://openalex.org/W2414933268","https://openalex.org/W2116955854"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}