{"id":"https://openalex.org/W2004254191","doi":"https://doi.org/10.1249/00005768-199002000-00015","title":"Physiologic and structural indices of vascular function in paraplegics","display_name":"Physiologic and structural indices of vascular function in paraplegics","publication_year":1990,"publication_date":"1990-02-01","ids":{"openalex":"https://openalex.org/W2004254191","doi":"https://doi.org/10.1249/00005768-199002000-00015","mag":"2004254191","pmid":"https://pubmed.ncbi.nlm.nih.gov/2406550"},"language":"en","primary_location":{"id":"doi:10.1249/00005768-199002000-00015","doi":"https://doi.org/10.1249/00005768-199002000-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1249/00005768-199002000-00015","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine & Science in Sports & Exercise","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059382904","display_name":"Jeffrey S. Shenberger","orcid":"https://orcid.org/0000-0003-4845-0847","observed_orcids":["https://orcid.org/0000-0003-4845-0847"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JEFFREY S. SHENBERGER","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","Department of Medicine, Milton S Hershey Medical Center, Pennsylvania State University, Hershey 17033"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Medicine, Milton S Hershey Medical Center, Pennsylvania State University, Hershey 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021510110","display_name":"GRETCHEN J. LEAMAN","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"GRETCHEN J. LEAMAN","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","Pennsylvania State Univ#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Pennsylvania State Univ#TAB#","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071569522","display_name":"Marsha M. Neumyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"MARSHA M. NEUMYER","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","Pennsylvania State Univ#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Pennsylvania State Univ#TAB#","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057426982","display_name":"Timothy I. Musch","orcid":"https://orcid.org/0000-0003-1599-1751","observed_orcids":["https://orcid.org/0000-0003-1599-1751"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"TIMOTHY I. MUSCH","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","Pennsylvania State Univ#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Pennsylvania State Univ#TAB#","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065596315","display_name":"Lawrence I. Sinoway","orcid":"https://orcid.org/0000-0001-9053-5153","observed_orcids":["https://orcid.org/0000-0001-9053-5153"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]},{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"LAWRENCE I. SINOWAY","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","Department of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA 17033","institution_ids":["https://openalex.org/I130769515","https://openalex.org/I82783531"]},{"raw_affiliation_string":"Department of Medicine","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.35034014,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"22","issue":"1","first_page":"96???101","last_page":"96???101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9229000210762024,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9229000210762024,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.07100000232458115,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paraplegia","display_name":"paraplegia","score":0.9300000071525574},{"id":"https://openalex.org/keywords/wheelchair-users","display_name":"wheelchair users","score":0.6930000185966492},{"id":"https://openalex.org/keywords/forearm-blood-flow","display_name":"forearm blood flow","score":0.6430000066757202},{"id":"https://openalex.org/keywords/reactive-hyperemia","display_name":"reactive hyperemia","score":0.9089999794960022},{"id":"https://openalex.org/keywords/brachial-artery-diameter","display_name":"brachial artery diameter","score":0.859000027179718},{"id":"https://openalex.org/keywords/peripheral-vasodilation","display_name":"peripheral vasodilation","score":0.7839999794960022},{"id":"https://openalex.org/keywords/resistance-vessels","display_name":"resistance vessels","score":0.5239999890327454},{"id":"https://openalex.org/keywords/arterial-occlusion","display_name":"arterial occlusion","score":0.722000002861023}],"concepts":[{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.494476318359375},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.42828547954559326},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3617088198661804},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.32085976004600525},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.15206730365753174},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1194412112236023},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.03761675953865051}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000886","descriptor_name":"Anthropometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001783","descriptor_name":"Blood Flow Velocity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005542","descriptor_name":"Forearm","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006940","descriptor_name":"Hyperemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006940","descriptor_name":"Hyperemia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010264","descriptor_name":"Paraplegia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010264","descriptor_name":"Paraplegia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D014664","descriptor_name":"Vasodilation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1249/00005768-199002000-00015","doi":"https://doi.org/10.1249/00005768-199002000-00015","is_oa":false,"landing_page_url":"https://doi.org/10.1249/00005768-199002000-00015","pdf_url":null,"source":{"id":"https://openalex.org/S14544163","display_name":"Medicine & Science in Sports & Exercise","issn_l":"0195-9131","issn":["0195-9131","1530-0315"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine & Science in Sports & Exercise","raw_type":"journal-article"},{"id":"pmid:2406550","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2406550","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine and science in sports and exercise","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2373323250","display_name":"PERIPHERAL BLOOD FLOW CHARACTERISTICS","funder_award_id":"K08HL001744","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4073528644","display_name":null,"funder_award_id":"HL 01744","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2776754125","https://openalex.org/W1996375579","https://openalex.org/W2017641348","https://openalex.org/W2097238727","https://openalex.org/W2090769060","https://openalex.org/W2106591014","https://openalex.org/W2166068914","https://openalex.org/W2093922647","https://openalex.org/W2015909387","https://openalex.org/W2056498562"],"abstract_inverted_index":{"In":[0],"an":[1,166],"effort":[2],"to":[3,165,169,175],"determine":[4],"whether":[5],"chronic":[6,160],"physical":[7],"forearm":[8,19,100],"activity":[9,163],"would":[10],"increase":[11],"both":[12],"structural":[13,80,177],"and":[14,40,99,132,174],"physiologic":[15],"indices":[16],"of":[17,28,34,52,62,65,78,82,97,179],"peripheral":[18],"vasodilation,":[20],"we":[21],"studied":[22],"a":[23,79,115,133,176],"group":[24],"(N":[25],"=":[26,104],"7)":[27],"individuals":[29],"chronically":[30],"performing":[31],"high":[32],"levels":[33],"arm":[35],"work,":[36],"young":[37],"wheelchair-confined":[38],"paraplegics,":[39],"compared":[41],"them":[42],"with":[43,114],"ten":[44],"young,":[45],"able":[46],"bodied":[47],"control":[48],"subjects.":[49],"The":[50,76],"index":[51,77],"vasodilator":[53],"capacity":[54],"was":[55,87],"the":[56,60,68,85,88,112,155],"flow":[57,73,102],"response":[58,74],"following":[59],"release":[61],"10":[63],"min":[64],"arterial":[66],"occlusion,":[67],"peak":[69],"reactive":[70],"hyperemic":[71],"blood":[72,101],"(RHBF).":[75],"effect":[81],"training":[83],"on":[84],"vasculature":[86],"brachial":[89,135],"artery":[90,136],"diameter":[91,137],"(cm)":[92],"derived":[93],"by":[94],"simultaneous":[95],"measurement":[96],"velocity":[98],"(area":[103],"flow.forearm":[105],"volume.velocity-1).":[106],"Vascular":[107],"function":[108],"differed":[109],"significantly":[110],"between":[111],"groups,":[113],"greater":[116],"RHBF":[117],"(paraplegics,":[118,140],"53.8":[119],"+/-":[120,124,142,147],"3.7;":[121],"controls,":[122,145],"38.2":[123],"1.5":[125],"ml.min-1.100":[126],"ml-1;":[127],"P":[128,150],"less":[129,151],"than":[130,152],"0.05)":[131,153],"larger":[134],"at":[138],"rest":[139],"0.4":[141],"0.01":[143],"vs":[144],"0.3":[146],"0.02":[148],"cm;":[149],"in":[154],"paraplegics.":[156],"We":[157],"conclude":[158],"that":[159],"upper":[161],"extremity":[162],"leads":[164],"enhanced":[167],"capability":[168],"vasodilate":[170],"resistance":[171],"vessels":[172],"acutely":[173],"dilation":[178],"large":[180],"conductance":[181],"vessels.":[182]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}