{"id":"https://openalex.org/W2004247011","doi":"https://doi.org/10.1016/j.etp.2007.02.002","title":"A modified Ames assay reveals the mutagenicity of native cigarette mainstream smoke and its gas vapour phase","display_name":"A modified Ames assay reveals the mutagenicity of native cigarette mainstream smoke and its gas vapour phase","publication_year":2007,"publication_date":"2007-06-07","ids":{"openalex":"https://openalex.org/W2004247011","doi":"https://doi.org/10.1016/j.etp.2007.02.002","mag":"2004247011","pmid":"https://pubmed.ncbi.nlm.nih.gov/17555953"},"language":"en","primary_location":{"id":"doi:10.1016/j.etp.2007.02.002","doi":"https://doi.org/10.1016/j.etp.2007.02.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.etp.2007.02.002","pdf_url":null,"source":{"id":"https://openalex.org/S93526581","display_name":"Experimental and Toxicologic Pathology","issn_l":"0940-2993","issn":["0940-2993","1618-1433"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Toxicologic Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059863738","display_name":"Michaela Aufderheide","orcid":"https://orcid.org/0000-0003-0928-8445","observed_orcids":["https://orcid.org/0000-0003-0928-8445"]},"institutions":[{"id":"https://openalex.org/I4210111966","display_name":"Fraunhofer Institute for Toxicology and Experimental Medicine","ror":"https://ror.org/02byjcr11","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210111966","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Michaela Aufderheide","raw_affiliation_strings":["Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, Hannover, Germany. michaela.aufderheide@item.fraunhofer.de","Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625 Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, Hannover, Germany. michaela.aufderheide@item.fraunhofer.de","institution_ids":["https://openalex.org/I4210111966"]},{"raw_affiliation_string":"Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625 Hannover, Germany","institution_ids":["https://openalex.org/I4210111966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042823681","display_name":"Helga Gressmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210111966","display_name":"Fraunhofer Institute for Toxicology and Experimental Medicine","ror":"https://ror.org/02byjcr11","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210111966","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Helga Gressmann","raw_affiliation_strings":["Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625 Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of In-Vitro Toxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Nikolai-Fuchs-Strasse 1, 30625 Hannover, Germany","institution_ids":["https://openalex.org/I4210111966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5059863738"],"corresponding_institution_ids":["https://openalex.org/I4210111966"],"apc_list":null,"apc_paid":null,"fwci":1.156,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.7845476,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"58","issue":"6","first_page":"383","last_page":"392"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11493","display_name":"Water Treatment and Disinfection","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mainstream-smoke","display_name":"mainstream smoke","score":0.9190000295639038},{"id":"https://openalex.org/keywords/mutagenicity","display_name":"mutagenicity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/ames-test","display_name":"Ames test","score":0.5989999771118164},{"id":"https://openalex.org/keywords/smoking-machine","display_name":"smoking machine","score":0.7549999952316284},{"id":"https://openalex.org/keywords/salmonella-typhimurium","display_name":"Salmonella typhimurium","score":0.925000011920929},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":0.6940000057220459},{"id":"https://openalex.org/keywords/aerosol-exposure","display_name":"aerosol exposure","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C129990765","wikidata":"https://www.wikidata.org/wiki/Q7508482","display_name":"Sidestream smoke","level":3,"score":0.8409185409545898},{"id":"https://openalex.org/C117632636","wikidata":"https://www.wikidata.org/wiki/Q30912","display_name":"Ames test","level":4,"score":0.6600675582885742},{"id":"https://openalex.org/C58874564","wikidata":"https://www.wikidata.org/wiki/Q130768","display_name":"Smoke","level":2,"score":0.6585580110549927},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.638566792011261},{"id":"https://openalex.org/C2993351451","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Cigarette smoke","level":2,"score":0.6250293850898743},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5526465177536011},{"id":"https://openalex.org/C3020013744","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Gas phase","level":2,"score":0.5053675770759583},{"id":"https://openalex.org/C2778355491","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Tobacco smoke","level":2,"score":0.4475491940975189},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.4207209348678589},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.41015997529029846},{"id":"https://openalex.org/C2781065037","wikidata":"https://www.wikidata.org/wiki/Q150839","display_name":"Salmonella","level":3,"score":0.40645813941955566},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.35223227739334106},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22070801258087158},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1269587278366089},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005740","descriptor_name":"Gases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009152","descriptor_name":"Mutagenicity Tests","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D009152","descriptor_name":"Mutagenicity Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D009153","descriptor_name":"Mutagens","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D012486","descriptor_name":"Salmonella typhimurium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012486","descriptor_name":"Salmonella typhimurium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014028","descriptor_name":"Tobacco Smoke Pollution","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014835","descriptor_name":"Volatilization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.etp.2007.02.002","doi":"https://doi.org/10.1016/j.etp.2007.02.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.etp.2007.02.002","pdf_url":null,"source":{"id":"https://openalex.org/S93526581","display_name":"Experimental and Toxicologic Pathology","issn_l":"0940-2993","issn":["0940-2993","1618-1433"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Toxicologic Pathology","raw_type":"journal-article"},{"id":"pmid:17555953","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17555953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie","raw_type":"Journal Article"},{"id":"pmh:oai:fraunhofer.de:N-63133","doi":null,"is_oa":false,"landing_page_url":"http://publica.fraunhofer.de/documents/N-63133.html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400801","display_name":"Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Fraunhofer ITEM","raw_type":"Journal Article"},{"id":"pmh:oai:publica.fraunhofer.de:publica/213509","doi":null,"is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/213509","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322099","display_name":"Korea Institute of Energy Research","ror":"https://ror.org/0298pes53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1965433424","https://openalex.org/W1966456621","https://openalex.org/W1967854466","https://openalex.org/W1970276930","https://openalex.org/W1973195696","https://openalex.org/W2003241922","https://openalex.org/W2005156172","https://openalex.org/W2005932183","https://openalex.org/W2013675206","https://openalex.org/W2014592407","https://openalex.org/W2017067698","https://openalex.org/W2023670376","https://openalex.org/W2026051826","https://openalex.org/W2037433191","https://openalex.org/W2055294823","https://openalex.org/W2075762160","https://openalex.org/W2079797036","https://openalex.org/W2087362148","https://openalex.org/W2087646741","https://openalex.org/W2145678417","https://openalex.org/W2166853334","https://openalex.org/W2169358061","https://openalex.org/W2432888119"],"related_works":["https://openalex.org/W2393783753","https://openalex.org/W1963590746","https://openalex.org/W2032930312","https://openalex.org/W2343824066","https://openalex.org/W2014592407","https://openalex.org/W2154523730","https://openalex.org/W2376178030","https://openalex.org/W2543485760","https://openalex.org/W4307774717","https://openalex.org/W2080454864"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}