{"id":"https://openalex.org/W2004182889","doi":"https://doi.org/10.1136/archdischild-2014-307384.521","title":"PS-222 Staphylococcus Capitis In Neonatal Late-onset Sepsis: Unexpected Worldwide Dissemination Of An Endemic Multi-resistant Clone","display_name":"PS-222 Staphylococcus Capitis In Neonatal Late-onset Sepsis: Unexpected Worldwide Dissemination Of An Endemic Multi-resistant Clone","publication_year":2014,"publication_date":"2014-10-01","ids":{"openalex":"https://openalex.org/W2004182889","doi":"https://doi.org/10.1136/archdischild-2014-307384.521","mag":"2004182889"},"language":"en","primary_location":{"id":"doi:10.1136/archdischild-2014-307384.521","doi":"https://doi.org/10.1136/archdischild-2014-307384.521","is_oa":true,"landing_page_url":"https://doi.org/10.1136/archdischild-2014-307384.521","pdf_url":"https://adc.bmj.com/content/archdischild/99/Suppl_2/A193.1.full.pdf","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neonatal Sepsis","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://adc.bmj.com/content/archdischild/99/Suppl_2/A193.1.full.pdf","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063350863","display_name":"Marine Butin","orcid":"https://orcid.org/0000-0001-9453-4641","observed_orcids":["https://orcid.org/0000-0001-9453-4641"]},"institutions":[{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"M Butin","raw_affiliation_strings":["Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]},{"raw_affiliation_string":"1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030636312","display_name":"Patr\u00edcia Martins-Sim\u00f5es","orcid":"https://orcid.org/0000-0001-5130-6016","observed_orcids":["https://orcid.org/0000-0001-5130-6016"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"P Martins Simoes","raw_affiliation_strings":["U1111 - CIRI, Inserm, Lyon, France","2U1111 - CIRI, Inserm, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U1111 - CIRI, Inserm, Lyon, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210161906"]},{"raw_affiliation_string":"2U1111 - CIRI, Inserm, Lyon, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210161906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045613894","display_name":"Hajar Lemriss","orcid":"https://orcid.org/0000-0003-2858-731X","observed_orcids":["https://orcid.org/0000-0003-2858-731X"]},"institutions":[{"id":"https://openalex.org/I4210140404","display_name":"Laboratoire de Recherche et d\u2019Analyses M\u00e9dicales de la Fraternelle de la Gendarmerie Royale","ror":"https://ror.org/031y5ny63","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210140404"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"H Lemriss","raw_affiliation_strings":["Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","3Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","institution_ids":["https://openalex.org/I4210140404"]},{"raw_affiliation_string":"3Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","institution_ids":["https://openalex.org/I4210140404"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011379957","display_name":"Sana\u00e2 Lemriss","orcid":"https://orcid.org/0000-0001-5183-6148","observed_orcids":["https://orcid.org/0000-0001-5183-6148"]},"institutions":[{"id":"https://openalex.org/I4210140404","display_name":"Laboratoire de Recherche et d\u2019Analyses M\u00e9dicales de la Fraternelle de la Gendarmerie Royale","ror":"https://ror.org/031y5ny63","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210140404"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"S Lemriss","raw_affiliation_strings":["Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","3Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","institution_ids":["https://openalex.org/I4210140404"]},{"raw_affiliation_string":"3Laboratoire de Recherche Et d\u2019Analyses M\u00e9dicales, Fraternelle de La Gendarmerie Royale, Rabbat, Morocco","institution_ids":["https://openalex.org/I4210140404"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065171970","display_name":"Fran\u00e7ois Vandenesch","orcid":"https://orcid.org/0000-0001-9412-7106","observed_orcids":["https://orcid.org/0000-0001-9412-7106"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210161906","display_name":"Centre International de Recherche en Infectiologie","ror":"https://ror.org/059sz6q14","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I113428412","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I203339264","https://openalex.org/I4210100596","https://openalex.org/I4210161906","https://openalex.org/I4405259976"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Vandenesch","raw_affiliation_strings":["U1111 - CIRI, Inserm, Lyon, France","2U1111 - CIRI, Inserm, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U1111 - CIRI, Inserm, Lyon, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210161906"]},{"raw_affiliation_string":"2U1111 - CIRI, Inserm, Lyon, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210161906"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026637793","display_name":"Olivier Claris","orcid":"https://orcid.org/0000-0001-5006-0317","observed_orcids":["https://orcid.org/0000-0001-5006-0317"]},"institutions":[{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"O Claris","raw_affiliation_strings":["NICU, Hospices Civils de Lyon, Lyon, France","4NICU, Hospices Civils de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NICU, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]},{"raw_affiliation_string":"4NICU, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112679977","display_name":"JC Picaud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"JC Picaud","raw_affiliation_strings":["NICU, Hospices Civils de Lyon, Lyon, France","4NICU, Hospices Civils de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NICU, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]},{"raw_affiliation_string":"4NICU, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026659189","display_name":"JP Rasigade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"JP Rasigade","raw_affiliation_strings":["Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]},{"raw_affiliation_string":"1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069009054","display_name":"Frederic J. Laurent","orcid":"https://orcid.org/0000-0003-0609-9091","observed_orcids":["https://orcid.org/0000-0003-0609-9091","https://orcid.org/0009-0000-6066-4114","https://orcid.org/0000-0001-7563-9800"]},"institutions":[{"id":"https://openalex.org/I4210100596","display_name":"Hospices Civils de Lyon","ror":"https://ror.org/01502ca60","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210100596"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"F Laurent","raw_affiliation_strings":["Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]},{"raw_affiliation_string":"1Clinical Microbiology, Hospices Civils de Lyon, Lyon, France","institution_ids":["https://openalex.org/I4210100596"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"A193.1","last_page":"A193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcus-capitis","display_name":"Staphylococcus capitis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/late-onset-sepsis","display_name":"late-onset sepsis","score":0.9490000009536743},{"id":"https://openalex.org/keywords/neonatal-sepsis","display_name":"neonatal sepsis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.7649999856948853},{"id":"https://openalex.org/keywords/antimicrobial-resistance-dissemination","display_name":"antimicrobial resistance dissemination","score":0.578000009059906},{"id":"https://openalex.org/keywords/vancomycin-heteroresistance","display_name":"vancomycin heteroresistance","score":0.8970000147819519},{"id":"https://openalex.org/keywords/methicillin-resistance","display_name":"methicillin resistance","score":0.8389999866485596},{"id":"https://openalex.org/keywords/aminoglycoside-resistance","display_name":"aminoglycoside resistance","score":0.8970000147819519},{"id":"https://openalex.org/keywords/sccmec-typing","display_name":"SCCmec typing","score":0.9419999718666077},{"id":"https://openalex.org/keywords/molecular-epidemiology","display_name":"molecular epidemiology","score":0.5860000252723694},{"id":"https://openalex.org/keywords/daptomycin","display_name":"daptomycin","score":0.6990000009536743},{"id":"https://openalex.org/keywords/linezolid","display_name":"linezolid","score":0.9850000143051147}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9354763031005859},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6019386649131775},{"id":"https://openalex.org/C81089528","wikidata":"https://www.wikidata.org/wiki/Q5134986","display_name":"clone (Java method)","level":3,"score":0.5207076668739319},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.4841764271259308},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4668937921524048},{"id":"https://openalex.org/C2777334864","wikidata":"https://www.wikidata.org/wiki/Q34879","display_name":"Staphylococcal infections","level":4,"score":0.45590442419052124},{"id":"https://openalex.org/C2775953899","wikidata":"https://www.wikidata.org/wiki/Q6993495","display_name":"Neonatal sepsis","level":3,"score":0.41542285680770874},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23559734225273132},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.11129254102706909},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08893835544586182},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.04456070065498352},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1136/archdischild-2014-307384.521","doi":"https://doi.org/10.1136/archdischild-2014-307384.521","is_oa":true,"landing_page_url":"https://doi.org/10.1136/archdischild-2014-307384.521","pdf_url":"https://adc.bmj.com/content/archdischild/99/Suppl_2/A193.1.full.pdf","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neonatal Sepsis","raw_type":"proceedings-article"},{"id":"pmh:oai:open-archive.highwire.org:archdischild:99/Suppl_2/A193-a","doi":null,"is_oa":false,"landing_page_url":"http://adc.bmj.com/cgi/content/short/99/Suppl_2/A193-a","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1136/archdischild-2014-307384.521","doi":"https://doi.org/10.1136/archdischild-2014-307384.521","is_oa":true,"landing_page_url":"https://doi.org/10.1136/archdischild-2014-307384.521","pdf_url":"https://adc.bmj.com/content/archdischild/99/Suppl_2/A193.1.full.pdf","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neonatal Sepsis","raw_type":"proceedings-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004182889.pdf","grobid_xml":"https://content.openalex.org/works/W2004182889.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2924664342","https://openalex.org/W1878688897","https://openalex.org/W1984402144","https://openalex.org/W3020029772","https://openalex.org/W3008410385","https://openalex.org/W2582094738","https://openalex.org/W2248279190","https://openalex.org/W4387326835","https://openalex.org/W2315301165","https://openalex.org/W4408046346"],"abstract_inverted_index":{"Background":[0],"Multi-resistant":[1],"Staphylococcus":[2],"capitis":[3,31,48,94,186],"NRCS-A":[4,106,170,199,235],"is":[5],"involved":[6],"in":[7,11,189,236],"late-onset":[8],"sepsis":[9],"(LOS)":[10],"French":[12],"NICUs.":[13,190],"Aims":[14],"To":[15,67],"investigate":[16],"the":[17,117,203,212,240,247],"geographical":[18],"distribution":[19,183],"of":[20,70,99,149,154,184,215,242],"NRCS-A,":[21,187],"and":[22,45,63,84,102,134,137,142,156,209,220,238,246],"to":[23,105,198,223,226,234],"precise":[24],"its":[25,221],"susceptibility":[26,65,130,144],"profile.":[27],"Methods":[28],"Twelve":[29],"S.":[30,47,93,185],"isolates":[32,49,171,196],"from":[33,50,147,200],"distant":[34],"NICUs":[35],"(Australia,":[36],"Belgium,":[37],"France,":[38],"United":[39],"Kingdom,":[40],"n":[41],"=":[42],"3":[43],"each)":[44],"2":[46],"adult":[51,150],"patients":[52],"were":[53,103],"analysed":[54],"using":[55],"PFGE,":[56],"SCCmec":[57,113],"typing,":[58],"dru-typing,":[59],"a":[60,110,122,127,231],"MLST-like":[61],"analysis,":[62],"antimicrobial":[64,129,143,251],"testing.":[66],"explore":[68],"impact":[69],"vancomycin":[71,138,155,227],"selective":[72,228,232],"pressure,":[73,229],"after":[74],"15":[75],"daily":[76],"subcultures":[77],"with":[78],"vancomycin,":[79,82],"we":[80,192],"determined":[81],"daptomycin":[83,157],"linezolid":[85],"minimal":[86],"inhibitory":[87],"concentrations":[88],"(MICs).":[89],"Results":[90],"All":[91],"NICU":[92,195],"(i)":[95],"shared":[96],">80%":[97],"similarity":[98],"PFGE":[100],"profile":[101,131,219],"similar":[104],"profile,":[107],"(ii)":[108],"harboured":[109,126],"type":[111],"V-related":[112],"element,":[114],"(iii)":[115],"exhibited":[116],"same":[118,128],"dru-type,":[119],"(iv)":[120],"formed":[121],"monophyletic":[123],"group,":[124],"(v)":[125],"including":[132],"aminoglycosides":[133],"methicillin":[135],"resistance,":[136],"heteroresistance.":[139],"These":[140],"molecular":[141],"profiles":[145],"differed":[146],"those":[148],"isolates.":[151],"An":[152],"increase":[153],"(but":[158],"not":[159],"linezolid)":[160],"MICs":[161],"was":[162],"observed,":[163],"significantly":[164],"faster":[165],"(p":[166],"<":[167],"0.05)":[168],"for":[169,249],"than":[172],"other":[173],"tested":[174],"strains.":[175],"Conclusion":[176],"Our":[177],"analysis":[178],"demonstrates":[179],"an":[180],"unexpected":[181],"worldwide":[182],"specifically":[188],"Recently,":[191],"collected":[193],"complementary":[194],"belonging":[197],"Norway,":[201],"Denmark,":[202],"Netherlands,":[204],"USA,":[205],"Brazil,":[206],"New":[207],"Zealand":[208],"Canada,":[210],"confirming":[211],"worrisome":[213],"dissemination":[214],"NRCS-A.":[216],"Its":[217],"multi-resistant":[218],"ability":[222],"rapidly":[224],"adapt":[225],"constitute":[230],"advantage":[233],"NICUs,":[237],"raise":[239],"issue":[241],"potential":[243],"therapeutic":[244],"failure":[245],"need":[248],"alternative":[250],"regimens.":[252]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}