{"id":"https://openalex.org/W2004140403","doi":"https://doi.org/10.3109/00365517209102760","title":"Sequential Changes of Plasma Proteins after Surgical Trauma","display_name":"Sequential Changes of Plasma Proteins after Surgical Trauma","publication_year":1972,"publication_date":"1972-01-01","ids":{"openalex":"https://openalex.org/W2004140403","doi":"https://doi.org/10.3109/00365517209102760","mag":"2004140403","pmid":"https://pubmed.ncbi.nlm.nih.gov/5041008"},"language":"en","primary_location":{"id":"doi:10.3109/00365517209102760","doi":"https://doi.org/10.3109/00365517209102760","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365517209102760","pdf_url":null,"source":{"id":"https://openalex.org/S5501027","display_name":"Scandinavian Journal of Clinical and Laboratory Investigation","issn_l":"0036-5513","issn":["0036-5513","1502-7686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Clinical and Laboratory Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111522571","display_name":"Karl Fredrik Aronsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"K.-F. Aronsen","raw_affiliation_strings":["Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051296485","display_name":"G\u00f6ran R. Ekelund","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"G. Ekelund","raw_affiliation_strings":["Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111627455","display_name":"Co. Kindmark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Co. Kindmark","raw_affiliation_strings":["Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110072701","display_name":"C.\u2010B. Laurell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"C.-B. Laurell","raw_affiliation_strings":["Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery and Clinical Chemistry, University of Lund, Malm\u00f6 General Hospital, Malm\u00f6, Sweden","institution_ids":["https://openalex.org/I187531555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I187531555"],"apc_list":null,"apc_paid":null,"fwci":2.6356,"has_fulltext":false,"cited_by_count":350,"citation_normalized_percentile":{"value":0.89358579,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"29","issue":"sup124","first_page":"127","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":0.5619999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms","score":0.5619999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.19539999961853027,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.14100000262260437,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plasma-proteins","display_name":"plasma proteins","score":0.8149999976158142},{"id":"https://openalex.org/keywords/acute-phase-response","display_name":"acute phase response","score":0.8090000152587891},{"id":"https://openalex.org/keywords/surgical-trauma","display_name":"surgical trauma","score":0.9070000052452087},{"id":"https://openalex.org/keywords/cholecystectomy","display_name":"cholecystectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mastectomy","display_name":"mastectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.8529999852180481},{"id":"https://openalex.org/keywords/antichymotrypsin","display_name":"antichymotrypsin","score":0.8389999866485596},{"id":"https://openalex.org/keywords/alpha-1-acid-glycoprotein","display_name":"alpha-1-acid glycoprotein","score":0.7770000100135803},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9039999842643738},{"id":"https://openalex.org/keywords/haptoglobin","display_name":"haptoglobin","score":0.9079999923706055},{"id":"https://openalex.org/keywords/alpha-1-antitrypsin","display_name":"alpha-1-antitrypsin","score":0.859000027179718},{"id":"https://openalex.org/keywords/transferrin","display_name":"transferrin","score":0.8669999837875366},{"id":"https://openalex.org/keywords/prealbumin","display_name":"prealbumin","score":0.8450000286102295},{"id":"https://openalex.org/keywords/alpha-2-macroglobulin","display_name":"alpha2-macroglobulin","score":0.8309999704360962},{"id":"https://openalex.org/keywords/internal-standard","display_name":"internal standard","score":0.7020000219345093},{"id":"https://openalex.org/keywords/postoperative-changes","display_name":"postoperative changes","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C2776474381","wikidata":"https://www.wikidata.org/wiki/Q409414","display_name":"Hemopexin","level":4,"score":0.9138121604919434},{"id":"https://openalex.org/C57194454","wikidata":"https://www.wikidata.org/wiki/Q424211","display_name":"Acute-phase protein","level":3,"score":0.8556797504425049},{"id":"https://openalex.org/C206396517","wikidata":"https://www.wikidata.org/wiki/Q422025","display_name":"Haptoglobin","level":2,"score":0.8262791633605957},{"id":"https://openalex.org/C28452662","wikidata":"https://www.wikidata.org/wiki/Q422752","display_name":"Ceruloplasmin","level":2,"score":0.7551645636558533},{"id":"https://openalex.org/C30787643","wikidata":"https://www.wikidata.org/wiki/Q24779782","display_name":"Orosomucoid","level":3,"score":0.7054541707038879},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.6679229736328125},{"id":"https://openalex.org/C146543888","wikidata":"https://www.wikidata.org/wiki/Q425056","display_name":"Blood proteins","level":2,"score":0.6450034976005554},{"id":"https://openalex.org/C81358767","wikidata":"https://www.wikidata.org/wiki/Q321710","display_name":"Globulin","level":2,"score":0.6133634448051453},{"id":"https://openalex.org/C22814914","wikidata":"https://www.wikidata.org/wiki/Q410473","display_name":"Transferrin","level":2,"score":0.6057718992233276},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.57252436876297},{"id":"https://openalex.org/C2781054842","wikidata":"https://www.wikidata.org/wiki/Q6725283","display_name":"Macroglobulin","level":2,"score":0.5667633414268494},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.5644869804382324},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5219668745994568},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4629097580909729},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.43758854269981384},{"id":"https://openalex.org/C121157162","wikidata":"https://www.wikidata.org/wiki/Q419999","display_name":"Transthyretin","level":2,"score":0.42872804403305054},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39400967955589294},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3323436379432678},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.32935088872909546},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2537938356399536},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.21644127368927002},{"id":"https://openalex.org/C2776217839","wikidata":"https://www.wikidata.org/wiki/Q189621","display_name":"Heme","level":3,"score":0.13719233870506287},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002763","descriptor_name":"Cholecystectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007122","descriptor_name":"Immunoelectrophoresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008408","descriptor_name":"Mastectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/00365517209102760","doi":"https://doi.org/10.3109/00365517209102760","is_oa":false,"landing_page_url":"https://doi.org/10.3109/00365517209102760","pdf_url":null,"source":{"id":"https://openalex.org/S5501027","display_name":"Scandinavian Journal of Clinical and Laboratory Investigation","issn_l":"0036-5513","issn":["0036-5513","1502-7686"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Clinical and Laboratory Investigation","raw_type":"journal-article"},{"id":"pmid:5041008","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5041008","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of clinical and laboratory investigation. Supplementum","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W92290914","https://openalex.org/W121672891","https://openalex.org/W1696482745","https://openalex.org/W1731414354","https://openalex.org/W1965011982","https://openalex.org/W1971754545","https://openalex.org/W1989710231","https://openalex.org/W1990986783","https://openalex.org/W2002983094","https://openalex.org/W2019524205","https://openalex.org/W2027153643","https://openalex.org/W2037095201","https://openalex.org/W2044095144","https://openalex.org/W2069176124","https://openalex.org/W2074193041","https://openalex.org/W2085524414","https://openalex.org/W2087184285","https://openalex.org/W2326648679","https://openalex.org/W2367179591","https://openalex.org/W2394618465","https://openalex.org/W2405592926","https://openalex.org/W2411838391","https://openalex.org/W2430753305","https://openalex.org/W2442537206","https://openalex.org/W2468665588","https://openalex.org/W2474009287","https://openalex.org/W2528974569","https://openalex.org/W2616569894"],"related_works":["https://openalex.org/W2085524414","https://openalex.org/W2034100322","https://openalex.org/W338136136","https://openalex.org/W2324004369","https://openalex.org/W2150621731","https://openalex.org/W2083289496","https://openalex.org/W2008105487","https://openalex.org/W7155184524","https://openalex.org/W2093312323","https://openalex.org/W2126432898"],"abstract_inverted_index":{"The":[0,15,26,40,57,124],"response":[1,27],"of":[2],"18":[3],"plasma":[4],"proteins":[5],"after":[6,24,38],"cholecystectomy":[7],"has":[8,19],"been":[9,20],"followed":[10],"up":[11],"for":[12,66],"3":[13],"weeks.":[14],"acute":[16],"phase":[17],"reaction":[18,116],"compared":[21],"with":[22,117],"that":[23,43],"mastectomy.":[25],"to":[28,82],"these":[29],"tissue":[30],"lesions":[31],"were":[32],"very":[33],"similar":[34],"but":[35],"more":[36],"intense":[37],"cholecystectomy.":[39],"finding":[41],"suggest":[42],"a2-macroglobulin":[44],"may":[45],"be":[46],"used":[47],"as":[48],"an":[49],"internal":[50],"standard":[51],"since":[52],"no":[53],"apparent":[54],"changes":[55],"appear.":[56],"concentration":[58],"decreases":[59],"during":[60],"the":[61],"first":[62],"few":[63],"postoperative":[64],"days":[65],"albumin,":[67],"\u03b1-lipoproteins,":[68],"transferrin":[69],"and":[70,79,93,109],"prealbumin.":[71],"No":[72],"common":[73],"cause":[74],"is":[75],"probable.":[76],"C-reactive":[77],"protein":[78],"antichymotrypsin":[80],"begin":[81],"rise":[83],"within":[84,121],"eight":[85],"hours.":[86],"One":[87],"day":[88],"later":[89],"orosomucoid,":[90],"fibrinogen,":[91],"haptoglobin":[92],"\u03b11-antitrypsin":[94],"show":[95,126],"a":[96,114,118,122],"strong":[97],"reaction.":[98],"Hemopexin,":[99],"\u03b21c-globulin,":[100],"prothrombin,":[101],"ceruloplasmin,":[102],"Gc-globulin,":[103],"\u03b11,":[104],"easily":[105],"precipitable":[106],"glycoprotein,":[107],"plasminogen":[108],"cold":[110],"insoluble":[111],"globulin":[112],"showed":[113],"delayed":[115],"moderate":[119],"increase":[120],"week.":[123],"immunoglobulins":[125],"insignificant":[127],"changes.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}