{"id":"https://openalex.org/W2004116785","doi":"https://doi.org/10.1002/oby.20338","title":"Dexamethasone reduces energy expenditure and increases susceptibility to diet\u2010induced obesity in mice","display_name":"Dexamethasone reduces energy expenditure and increases susceptibility to diet\u2010induced obesity in mice","publication_year":2013,"publication_date":"2013-02-14","ids":{"openalex":"https://openalex.org/W2004116785","doi":"https://doi.org/10.1002/oby.20338","mag":"2004116785","pmid":"https://pubmed.ncbi.nlm.nih.gov/23408649","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4451231"},"language":"en","primary_location":{"id":"doi:10.1002/oby.20338","doi":"https://doi.org/10.1002/oby.20338","is_oa":true,"landing_page_url":"https://doi.org/10.1002/oby.20338","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.20338","source":{"id":"https://openalex.org/S29918858","display_name":"Obesity","issn_l":"1930-7381","issn":["1930-7381","1930-739X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.20338","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060206665","display_name":"Raffaella Poggioli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raffaella Poggioli","raw_affiliation_strings":["Division of Endocrinology, Diabetes, and Metabolism University of Miami Miller School of Medicine Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes, and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048322341","display_name":"Cintia B. Ueta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cintia B. Ueta","raw_affiliation_strings":["Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051703391","display_name":"Rafael Arrojo e Drigo","orcid":"https://orcid.org/0000-0001-7712-013X","observed_orcids":["https://orcid.org/0000-0001-7712-013X"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rafael Arrojo e Drigo","raw_affiliation_strings":["Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051495627","display_name":"Melany Castillo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melany Castillo","raw_affiliation_strings":["Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044191707","display_name":"Tatiana L. Fonseca","orcid":"https://orcid.org/0000-0003-2655-9585","observed_orcids":["https://orcid.org/0000-0003-2655-9585"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tatiana L. Fonseca","raw_affiliation_strings":["Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026395401","display_name":"Antonio Carlos Bianco","orcid":"https://orcid.org/0000-0001-7737-6813","observed_orcids":["https://orcid.org/0000-0001-7737-6813"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Antonio C. Bianco","raw_affiliation_strings":["Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology Diabetes and Metabolism University of Miami Miller School of Medicine Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"University of Miami Miller School of Medicine Division of Endocrinology Diabetes and Metabolism Miami Florida USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026395401"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":{"value":4980,"currency":"USD","value_usd":4980},"apc_paid":null,"fwci":1.863,"has_fulltext":true,"cited_by_count":76,"citation_normalized_percentile":{"value":0.83738585,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"21","issue":"9","first_page":"E415","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.03700000047683716,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.01940000057220459,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dexamethasone","display_name":"dexamethasone","score":1.0},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"energy expenditure","score":0.8259999752044678},{"id":"https://openalex.org/keywords/diet-induced-obesity","display_name":"diet-induced obesity","score":0.996999979019165},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.9929999709129333},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.6940000057220459},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/brown-adipose-tissue","display_name":"brown adipose tissue","score":0.8949999809265137},{"id":"https://openalex.org/keywords/thermogenesis","display_name":"thermogenesis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/ucp1","display_name":"UCP1","score":0.8840000033378601},{"id":"https://openalex.org/keywords/respiratory-quotient","display_name":"respiratory quotient","score":0.8610000014305115},{"id":"https://openalex.org/keywords/metabolic-rate","display_name":"metabolic rate","score":0.8320000171661377},{"id":"https://openalex.org/keywords/glucocorticoids","display_name":"glucocorticoids","score":0.753000020980835}],"concepts":[{"id":"https://openalex.org/C2780401358","wikidata":"https://www.wikidata.org/wiki/Q422252","display_name":"Dexamethasone","level":2,"score":0.935495913028717},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8574827313423157},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8393775224685669},{"id":"https://openalex.org/C151279926","wikidata":"https://www.wikidata.org/wiki/Q965695","display_name":"Thermogenesis","level":3,"score":0.7437076568603516},{"id":"https://openalex.org/C98488077","wikidata":"https://www.wikidata.org/wiki/Q1428512","display_name":"Respiratory quotient","level":2,"score":0.644773542881012},{"id":"https://openalex.org/C2776175330","wikidata":"https://www.wikidata.org/wiki/Q1365091","display_name":"Steatosis","level":2,"score":0.6442497968673706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6344271898269653},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6210492849349976},{"id":"https://openalex.org/C2780642333","wikidata":"https://www.wikidata.org/wiki/Q901269","display_name":"Brown adipose tissue","level":3,"score":0.6155354976654053},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.5031725764274597}],"mesh":[{"descriptor_ui":"D000071256","descriptor_name":"Uncoupling Protein 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001481","descriptor_name":"Basal Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002001","descriptor_name":"Adipose Tissue, Brown","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005234","descriptor_name":"Fatty Liver","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005938","descriptor_name":"Glucocorticoids","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D005938","descriptor_name":"Glucocorticoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D022722","descriptor_name":"Thermogenesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050154","descriptor_name":"Adiposity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1002/oby.20338","doi":"https://doi.org/10.1002/oby.20338","is_oa":true,"landing_page_url":"https://doi.org/10.1002/oby.20338","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.20338","source":{"id":"https://openalex.org/S29918858","display_name":"Obesity","issn_l":"1930-7381","issn":["1930-7381","1930-739X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity","raw_type":"journal-article"},{"id":"pmid:23408649","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23408649","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity (Silver Spring, Md.)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3418223","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4451231","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4451231","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4451231","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Obesity (Silver Spring)","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.781.8329","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.781.8329","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/34/e1/nihms434493.PMC4451231.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1002/oby.20338","doi":"https://doi.org/10.1002/oby.20338","is_oa":true,"landing_page_url":"https://doi.org/10.1002/oby.20338","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/oby.20338","source":{"id":"https://openalex.org/S29918858","display_name":"Obesity","issn_l":"1930-7381","issn":["1930-7381","1930-739X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obesity","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2127142383","display_name":null,"funder_award_id":"DK 65055","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4567732092","display_name":"Thyroid-adrenergic synergism and adaptive thermogenesis","funder_award_id":"R01DK065055","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004116785.pdf","grobid_xml":"https://content.openalex.org/works/W2004116785.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W27306674","https://openalex.org/W44823491","https://openalex.org/W1923807681","https://openalex.org/W1965079305","https://openalex.org/W1965276243","https://openalex.org/W1968522350","https://openalex.org/W1974269777","https://openalex.org/W1976555898","https://openalex.org/W1987396115","https://openalex.org/W1991845771","https://openalex.org/W1994514157","https://openalex.org/W1995185931","https://openalex.org/W1999429145","https://openalex.org/W2005827500","https://openalex.org/W2014122597","https://openalex.org/W2025688934","https://openalex.org/W2027996208","https://openalex.org/W2036456258","https://openalex.org/W2040328785","https://openalex.org/W2041066379","https://openalex.org/W2048192635","https://openalex.org/W2049079411","https://openalex.org/W2054020841","https://openalex.org/W2054125205","https://openalex.org/W2058815263","https://openalex.org/W2061962280","https://openalex.org/W2067333236","https://openalex.org/W2081953333","https://openalex.org/W2089004128","https://openalex.org/W2099438920","https://openalex.org/W2107958082","https://openalex.org/W2114821999","https://openalex.org/W2115274616","https://openalex.org/W2119926838","https://openalex.org/W2132358997","https://openalex.org/W2140596302","https://openalex.org/W2144285392","https://openalex.org/W2159967827","https://openalex.org/W2169311730","https://openalex.org/W2337250838"],"related_works":["https://openalex.org/W1992618900","https://openalex.org/W2067333236","https://openalex.org/W4405952310","https://openalex.org/W1482552654","https://openalex.org/W4237062404","https://openalex.org/W1975541020","https://openalex.org/W2096459247","https://openalex.org/W2797640654","https://openalex.org/W4225392200","https://openalex.org/W2909412223"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"how":[3],"long-term":[4],"treatment":[5,74,87,146],"with":[6,56,88,147],"dexamethasone":[7,42,57,73,89,148],"affects":[8],"energy":[9],"expenditure":[10],"and":[11,15,39,97,161,164],"adiposity":[12,163],"in":[13,67,94,102,114,122,132,136,149],"mice":[14],"whether":[16],"this":[17],"is":[18],"influenced":[19],"by":[20,80],"feeding":[21],"on":[22,33,41,71,106],"a":[23,34,127,150],"high-fat":[24],"diet":[25],"(HFD).":[26],"DESIGN":[27],"AND":[28],"METHODS:":[29],"Mice":[30],"were":[31],"placed":[32],"HFD":[35],"for":[36],"2":[37],"weeks":[38],"started":[40],"at":[43],"5":[44],"mg/kg":[45],"every":[46],"other":[47],"day":[48],"during":[49],"the":[50,68,81,84,91,103,110,123,137],"next":[51],"7":[52],"weeks.":[53],"RESULTS:":[54],"Treatment":[55],"increased":[58],"body":[59],"fat,":[60],"an":[61],"effect":[62],"that":[63],"was":[64,119],"more":[65],"pronounced":[66],"animals":[69,96,104],"kept":[70,105],"HFD;":[72],"also":[75],"worsened":[76],"liver":[77,165],"steatosis":[78],"caused":[79],"HFD.":[82,107],"At":[83],"same":[85],"time,":[86],"lowered":[90],"respiratory":[92],"quotient":[93],"chow-fed":[95],"slowed":[98],"nightly":[99],"metabolic":[100],"rate":[101],"In":[108],"addition,":[109],"acute":[111],"VO2":[112],"acceleration":[113],"response":[115],"to":[116],"\u03b23":[117],"adrenergic-stimulation":[118],"significantly":[120],"limited":[121],"dexamethasone-treated":[124],"animals,":[125],"as":[126],"result":[128],"of":[129,141,153,171],"marked":[130],"decrease":[131],"UCP-1":[133],"mRNA":[134],"observed":[135],"brown":[138,157],"adipose":[139,158],"tissue":[140,159],"these":[142],"animals.":[143],"CONCLUSIONS:":[144],"Long-term":[145],"mouse":[151],"model":[152],"diet-induced":[154],"obesity":[155],"decreases":[156],"thermogenesis":[160],"exaggerates":[162],"steatosis.":[166],"\u00a9":[167],"2013":[168],"American":[169],"Institute":[170],"Chemical":[172],"Engineers":[173],"AIChE":[174],"J,":[175],"2013.":[176]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}