{"id":"https://openalex.org/W2004042706","doi":"https://doi.org/10.1093/hmg/3.7.1053","title":"Absence of the XIST gene from late-replicating isodicentric X chromosomes in leukaemia","display_name":"Absence of the XIST gene from late-replicating isodicentric X chromosomes in leukaemia","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2004042706","doi":"https://doi.org/10.1093/hmg/3.7.1053","mag":"2004042706","pmid":"https://pubmed.ncbi.nlm.nih.gov/7981672"},"language":"en","primary_location":{"id":"doi:10.1093/hmg/3.7.1053","doi":"https://doi.org/10.1093/hmg/3.7.1053","is_oa":false,"landing_page_url":"https://doi.org/10.1093/hmg/3.7.1053","pdf_url":null,"source":{"id":"https://openalex.org/S166515463","display_name":"Human Molecular Genetics","issn_l":"0964-6906","issn":["0964-6906","1460-2083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Molecular Genetics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111104659","display_name":"Katrina A. Rack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]},{"id":"https://openalex.org/I4387152343","display_name":"MRC Molecular Haematology Unit","ror":"https://ror.org/02khxwt12","country_code":"GB","type":"facility","lineage":["https://openalex.org/I40120149","https://openalex.org/I4210087105","https://openalex.org/I4210110594","https://openalex.org/I4387152343","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K. A. Rack","raw_affiliation_strings":["MRC Molecular Haematology Unit, John Radcliffe Hospital, Headington, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Molecular Haematology Unit, John Radcliffe Hospital, Headington, Oxford, UK","institution_ids":["https://openalex.org/I2802742124","https://openalex.org/I4387152343"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048501611","display_name":"Jamel Chelly","orcid":"https://orcid.org/0000-0002-0939-8719","observed_orcids":["https://orcid.org/0000-0002-0939-8719"]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Chelly","raw_affiliation_strings":["Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe HospitalHeadington, Oxford OX3 9DU, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe HospitalHeadington, Oxford OX3 9DU, Oxford, UK","institution_ids":["https://openalex.org/I2802742124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060337902","display_name":"Richard J. Gibbons","orcid":"https://orcid.org/0000-0002-7680-9311","observed_orcids":["https://orcid.org/0000-0002-7680-9311"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. J. Gibbons","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087892570","display_name":"Sue H. Rider","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"S. Rider","raw_affiliation_strings":["Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital Headington, Oxford OX3 9DU, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital Headington, Oxford OX3 9DU, Oxford, UK","institution_ids":["https://openalex.org/I2802742124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112017201","display_name":"D. Rosen Benjamin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Benjamin","raw_affiliation_strings":["Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113561555","display_name":"R. G. Lafrenl\u00e8re","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. G. Lafrenl\u00e8re","raw_affiliation_strings":["Department of Genetics, Case Western Reserve University, School of Medicine 10900 Euclid Avenue, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Case Western Reserve University, School of Medicine 10900 Euclid Avenue, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108611534","display_name":"D. Oscier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799967250","display_name":"Royal Bournemouth Hospital","ror":"https://ror.org/01v14jr37","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799967250","https://openalex.org/I4387155041"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"D. Oscier","raw_affiliation_strings":["Department of Haematology, Royal Bournemouth Hospital Castle Lane East, Bournemouth BH7 7DW, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Royal Bournemouth Hospital Castle Lane East, Bournemouth BH7 7DW, UK","institution_ids":["https://openalex.org/I2799967250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051066209","display_name":"Rudi W. Hendriks","orcid":"https://orcid.org/0000-0003-2291-0382","observed_orcids":["https://orcid.org/0000-0003-2291-0382"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. W. Hendriks","raw_affiliation_strings":["Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043641502","display_name":"Ian Craig","orcid":"https://orcid.org/0000-0002-4063-1005","observed_orcids":["https://orcid.org/0000-0002-4063-1005"]},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"I. W. Craig","raw_affiliation_strings":["Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics Laboratory, Department of Biochemistry, Oxford University South Parks Road, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109872049","display_name":"Huntington F. Willard","orcid":"https://orcid.org/0000-0002-7755-0727","observed_orcids":["https://orcid.org/0000-0002-7755-0727"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. F. Willard","raw_affiliation_strings":["Department of Genetics, Case Western Reserve University, School of Medicine 10900 Euclid Avenue, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, Case Western Reserve University, School of Medicine 10900 Euclid Avenue, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038938677","display_name":"Anthony P. Monaco","orcid":"https://orcid.org/0000-0001-7480-3197","observed_orcids":["https://orcid.org/0000-0001-7480-3197"]},"institutions":[{"id":"https://openalex.org/I2802742124","display_name":"John Radcliffe Hospital","ror":"https://ror.org/0080acb59","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802742124","https://openalex.org/I4210127145","https://openalex.org/I4210147381"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. P. Monaco","raw_affiliation_strings":["Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital Headington, Oxford OX3 9DU, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital Headington, Oxford OX3 9DU, Oxford, UK","institution_ids":["https://openalex.org/I2802742124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021904108","display_name":"Veronica J. Buckle","orcid":"https://orcid.org/0000-0003-1195-2608","observed_orcids":["https://orcid.org/0000-0003-1195-2608"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"V. J. Buckle","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5021904108"],"corresponding_institution_ids":[],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":1.7988,"has_fulltext":false,"cited_by_count":74,"citation_normalized_percentile":{"value":0.84761201,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"3","issue":"7","first_page":"1053","last_page":"1059"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xist-gene","display_name":"Xist gene","score":0.9869999885559082},{"id":"https://openalex.org/keywords/x-chromosome-inactivation","display_name":"X chromosome inactivation","score":0.8650000095367432},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.7620000243186951},{"id":"https://openalex.org/keywords/xq13","display_name":"Xq13","score":0.902999997138977},{"id":"https://openalex.org/keywords/x-inactivation-center","display_name":"X inactivation center","score":0.7250000238418579},{"id":"https://openalex.org/keywords/gene-deletion","display_name":"gene deletion","score":0.6819999814033508},{"id":"https://openalex.org/keywords/inactive-x-chromosome","display_name":"inactive X chromosome","score":0.722000002861023},{"id":"https://openalex.org/keywords/xist-expression","display_name":"Xist expression","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C110411900","wikidata":"https://www.wikidata.org/wiki/Q18032385","display_name":"XIST","level":5,"score":0.9932391047477722},{"id":"https://openalex.org/C4323932","wikidata":"https://www.wikidata.org/wiki/Q898914","display_name":"X-inactivation","level":4,"score":0.8759266138076782},{"id":"https://openalex.org/C35158069","wikidata":"https://www.wikidata.org/wiki/Q61333","display_name":"X chromosome","level":3,"score":0.8618207573890686},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.846750795841217},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.5859801769256592},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5587072372436523},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48778802156448364},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4518031179904938},{"id":"https://openalex.org/C92509807","wikidata":"https://www.wikidata.org/wiki/Q13417137","display_name":"Dosage compensation","level":4,"score":0.43839210271835327}],"mesh":[{"descriptor_ui":"D000754","descriptor_name":"Anemia, Refractory, with Excess of Blasts","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002869","descriptor_name":"Chromosome Aberrations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004261","descriptor_name":"DNA Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004303","descriptor_name":"Dosage Compensation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005796","descriptor_name":"Genes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007948","descriptor_name":"Leukemia, Monocytic, Acute","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014960","descriptor_name":"X Chromosome","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D015973","descriptor_name":"Gene Expression Regulation, Leukemic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017404","descriptor_name":"In Situ Hybridization, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062085","descriptor_name":"RNA, Long Noncoding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/hmg/3.7.1053","doi":"https://doi.org/10.1093/hmg/3.7.1053","is_oa":false,"landing_page_url":"https://doi.org/10.1093/hmg/3.7.1053","pdf_url":null,"source":{"id":"https://openalex.org/S166515463","display_name":"Human Molecular Genetics","issn_l":"0964-6906","issn":["0964-6906","1460-2083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Molecular Genetics","raw_type":"journal-article"},{"id":"pmid:7981672","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7981672","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human molecular genetics","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-03990563v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-03990563","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Human Molecular Genetics, 1994, 3 (7), pp.1053-1059. ⟨10.1093/hmg/3.7.1053⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:open-archive.highwire.org:hmg:3/7/1053","doi":null,"is_oa":false,"landing_page_url":"http://hmg.oxfordjournals.org/cgi/content/short/3/7/1053","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2001841820","https://openalex.org/W1973445288","https://openalex.org/W2054897842","https://openalex.org/W2008098961","https://openalex.org/W1999696194","https://openalex.org/W1975906404","https://openalex.org/W1968116524","https://openalex.org/W1986277038","https://openalex.org/W2029872802","https://openalex.org/W2047333953"],"abstract_inverted_index":{"The":[0,21,106],"mechanism":[1],"of":[2,71,79,97,117],"X-inactivation":[3,16,49,118],"in":[4,44,77],"man":[5],"is":[6,30,94,111],"thought":[7],"to":[8,66],"involve":[9],"a":[10,67],"specific":[11,26],"cis-acting":[12],"locus":[13],"within":[14,73],"the":[15,35,48,55,80,101,115],"centre":[17],"at":[18,28],"Xq13":[19,29],"(1,2).":[20],"XIST":[22,81,98,110],"gene":[23],"(X":[24],"inactive":[25,36,90],"transcript)":[27],"ubiquitously":[31],"expressed":[32],"only":[33],"from":[34,100],"X":[37,61,104,123],"and":[38,91],"as":[39],"such":[40],"may":[41],"be":[42],"involved":[43],"or":[45],"influenced":[46],"by":[47],"process":[50],"(3,4).":[51],"We":[52,83],"have":[53,84],"localised":[54],"breakpoints":[56],"on":[57,119],"two":[58],"acquired":[59],"isodicentric":[60],"chromosomes":[62,88],"associated":[63],"with":[64],"leukaemia":[65],"450":[68],"kilobase":[69],"region":[70],"DNA":[72],"Xq13,":[74],"which":[75],"result":[76],"deletion":[78],"gene.":[82],"demonstrated":[85],"that":[86,92,109],"these":[87,120],"remain":[89],"there":[93],"no":[95],"evidence":[96],"expression":[99],"remaining":[102],"intact":[103],"chromosomes.":[105,124],"data":[107],"suggest":[108],"not":[112],"required":[113],"for":[114],"maintenance":[116],"somatically":[121],"rearranged":[122]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}