{"id":"https://openalex.org/W2004019285","doi":"https://doi.org/10.1073/pnas.96.18.10344","title":"Bacterial inactivation by using near- and supercritical carbon dioxide","display_name":"Bacterial inactivation by using near- and supercritical carbon dioxide","publication_year":1999,"publication_date":"1999-08-31","ids":{"openalex":"https://openalex.org/W2004019285","doi":"https://doi.org/10.1073/pnas.96.18.10344","mag":"2004019285","pmid":"https://pubmed.ncbi.nlm.nih.gov/10468610","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/17890"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.96.18.10344","doi":"https://doi.org/10.1073/pnas.96.18.10344","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.96.18.10344","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2004019285"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC17890","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067000365","display_name":"Angela K. Dillow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Angela K. Dillow","raw_affiliation_strings":["Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I31746571","https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069374909","display_name":"Fariba Dehghani","orcid":"https://orcid.org/0000-0002-7805-8101","observed_orcids":["https://orcid.org/0000-0002-7805-8101"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Fariba Dehghani","raw_affiliation_strings":["Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I31746571","https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055252245","display_name":"Jeffrey S. Hrkach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Jeffrey S. Hrkach","raw_affiliation_strings":["Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I31746571","https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015794408","display_name":"Neil R. Foster","orcid":"https://orcid.org/0000-0003-2479-7977","observed_orcids":["https://orcid.org/0000-0003-2479-7977"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Neil R. Foster","raw_affiliation_strings":["Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I31746571","https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042597057","display_name":"R\u00f3bert Langer","orcid":"https://orcid.org/0000-0003-4255-0492","observed_orcids":["https://orcid.org/0000-0003-4255-0492","https://orcid.org/0000-0001-5746-9940"]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]},{"id":"https://openalex.org/I4210092658","display_name":"Harvard\u2013MIT Division of Health Sciences and Technology","ror":"https://ror.org/00jjeh629","country_code":"US","type":"education","lineage":["https://openalex.org/I4210092658"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["AU","US"],"is_corresponding":false,"raw_author_name":"Robert Langer","raw_affiliation_strings":["Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455; School of Chemical and Industrial Engineering, University of New South Wales, Sydney, Australia 2052; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02139","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I31746571","https://openalex.org/I4210092658","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.5998,"has_fulltext":false,"cited_by_count":331,"citation_normalized_percentile":{"value":0.87777778,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"96","issue":"18","first_page":"10344","last_page":"10348"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.33469998836517334,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.33469998836517334,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10402","display_name":"Phase Equilibria and Thermodynamics","score":0.3093000054359436,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.2858999967575073,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacterial-inactivation","display_name":"bacterial inactivation","score":0.9179999828338623},{"id":"https://openalex.org/keywords/supercritical-carbon-dioxide","display_name":"supercritical carbon dioxide","score":0.9580000042915344},{"id":"https://openalex.org/keywords/near-critical-carbon-dioxide","display_name":"near-critical carbon dioxide","score":0.9860000014305115},{"id":"https://openalex.org/keywords/sterilization","display_name":"sterilization","score":0.8399999737739563},{"id":"https://openalex.org/keywords/biodegradable-polymers","display_name":"biodegradable polymers","score":0.7979999780654907},{"id":"https://openalex.org/keywords/poly-lactic-co-glycolic-acid","display_name":"poly(lactic-co-glycolic acid)","score":0.9639999866485596},{"id":"https://openalex.org/keywords/polylactic-acid","display_name":"polylactic acid","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C148761745","wikidata":"https://www.wikidata.org/wiki/Q1563203","display_name":"Sterilization (economics)","level":4,"score":0.8908786773681641},{"id":"https://openalex.org/C2777801237","wikidata":"https://www.wikidata.org/wiki/Q407473","display_name":"Ethylene oxide","level":4,"score":0.6544658541679382},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.6349755525588989},{"id":"https://openalex.org/C2781162966","wikidata":"https://www.wikidata.org/wiki/Q413769","display_name":"Polylactic acid","level":3,"score":0.6058541536331177},{"id":"https://openalex.org/C118419359","wikidata":"https://www.wikidata.org/wiki/Q682585","display_name":"Supercritical fluid","level":2,"score":0.597117006778717},{"id":"https://openalex.org/C134458231","wikidata":"https://www.wikidata.org/wiki/Q332582","display_name":"Supercritical carbon dioxide","level":3,"score":0.5967645645141602},{"id":"https://openalex.org/C530467964","wikidata":"https://www.wikidata.org/wiki/Q1997","display_name":"Carbon dioxide","level":2,"score":0.5808266997337341},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5488114356994629},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.47208496928215027},{"id":"https://openalex.org/C45211672","wikidata":"https://www.wikidata.org/wiki/Q4119016","display_name":"Biodegradable polymer","level":3,"score":0.4517667591571808},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.36454248428344727},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.343960165977478},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C536366893","wikidata":"https://www.wikidata.org/wiki/Q66076","display_name":"Foreign exchange market","level":3,"score":0.0},{"id":"https://openalex.org/C2983132609","wikidata":"https://www.wikidata.org/wiki/Q66076","display_name":"Foreign exchange","level":2,"score":0.0},{"id":"https://openalex.org/C556758197","wikidata":"https://www.wikidata.org/wiki/Q580018","display_name":"Monetary economics","level":1,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077182","descriptor_name":"Polylactic Acid-Polyglycolic Acid Copolymer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D001673","descriptor_name":"Biodegradation, Environmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008863","descriptor_name":"Microspheres","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011100","descriptor_name":"Polyglycolic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013171","descriptor_name":"Spores, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013242","descriptor_name":"Sterilization","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D013242","descriptor_name":"Sterilization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018407","descriptor_name":"Bacterial Physiological Phenomena","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.96.18.10344","doi":"https://doi.org/10.1073/pnas.96.18.10344","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.96.18.10344","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:188628","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC17890","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:10468610","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10468610","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:17890","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC17890/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:188628","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC17890","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W175252489","https://openalex.org/W1536081943","https://openalex.org/W1923399248","https://openalex.org/W1970238355","https://openalex.org/W1971549732","https://openalex.org/W1980803266","https://openalex.org/W1988470045","https://openalex.org/W1991440683","https://openalex.org/W1992657521","https://openalex.org/W1993883437","https://openalex.org/W2001685327","https://openalex.org/W2012389920","https://openalex.org/W2012807283","https://openalex.org/W2023153841","https://openalex.org/W2027367361","https://openalex.org/W2027491080","https://openalex.org/W2030660868","https://openalex.org/W2031803722","https://openalex.org/W2037683864","https://openalex.org/W2039634067","https://openalex.org/W2044356914","https://openalex.org/W2046133313","https://openalex.org/W2067927114","https://openalex.org/W2079686060","https://openalex.org/W2081995388","https://openalex.org/W2091470744","https://openalex.org/W2092682658","https://openalex.org/W2139438415","https://openalex.org/W2143213238","https://openalex.org/W2162294498","https://openalex.org/W2167194423","https://openalex.org/W4211147424","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4387339409","https://openalex.org/W2052366163","https://openalex.org/W2117013460","https://openalex.org/W7098479060","https://openalex.org/W2017210991","https://openalex.org/W2015031230","https://openalex.org/W4281766620","https://openalex.org/W2073358157","https://openalex.org/W3172159730","https://openalex.org/W7034043245"],"abstract_inverted_index":{"The":[0],"three":[1],"most":[2],"common":[3],"methods":[4,21],"of":[5,19,28,56,71,75,85,94,107],"sterilization":[6,27,57,123],"in":[7,32,43,82,121],"use":[8],"today":[9],"are":[10],"ethylene":[11],"oxide":[12],"exposure,":[13],"gamma-irradiation,":[14],"and":[15,36,42,81,103,116,142],"steam":[16],"sterilization.":[17],"Each":[18],"these":[20,140],"has":[22],"serious":[23],"limitations":[24],"for":[25],"the":[26,83,96,99,104,108,122,130],"some":[29],"materials":[30,145],"used":[31],"medicine,":[33],"especially":[34],"thermally":[35,141],"hydrolytically":[37,143],"sensitive":[38],"polymers":[39,113],"by":[40,58],"themselves":[41],"combination":[44],"with":[45],"proteins.":[46],"In":[47],"this":[48,65],"work,":[49],"we":[50,67],"demonstrate":[51],"a":[52,72,92],"potential":[53],"new":[54],"method":[55,66],"using":[59],"supercritical":[60],"fluid":[61,109],"carbon":[62],"dioxide.":[63],"Using":[64],"achieve":[68],"complete":[69],"inactivation":[70,131],"wide":[73],"variety":[74],"bacterial":[76],"organisms":[77],"at":[78],"moderate":[79],"temperatures":[80],"absence":[84],"organic":[86],"solvents":[87],"or":[88,136],"irradiation.":[89],"Sterilization":[90],"is":[91],"function":[93],"both":[95],"proximity":[97],"to":[98,139],"fluid's":[100],"critical":[101],"point":[102],"chemical":[105,137],"nature":[106],"itself.":[110],"When":[111],"biodegradable":[112],"poly(lactic-co-glycolic)":[114],"acid":[115,118],"polylactic":[117],"were":[119],"included":[120],"process,":[124],"there":[125],"was":[126,146],"no":[127,134],"effect":[128],"on":[129],"efficiency,":[132],"yet":[133],"physical":[135],"damage":[138],"labile":[144],"observed.":[147]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":14},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":17}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}