{"id":"https://openalex.org/W2004011968","doi":"https://doi.org/10.2337/diacare.24.4.654","title":"Baseline Characteristics of the Diabetic Participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)","display_name":"Baseline Characteristics of the Diabetic Participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W2004011968","doi":"https://doi.org/10.2337/diacare.24.4.654","mag":"2004011968","pmid":"https://pubmed.ncbi.nlm.nih.gov/11315826"},"language":"en","primary_location":{"id":"doi:10.2337/diacare.24.4.654","doi":"https://doi.org/10.2337/diacare.24.4.654","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.654","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/654/587499/654.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://diabetesjournals.org/care/article-pdf/24/4/654/587499/654.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006293947","display_name":"Joshua I. Barzilay","orcid":"https://orcid.org/0000-0001-7044-4166","observed_orcids":["https://orcid.org/0000-0001-7044-4166"]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua I. Barzilay","raw_affiliation_strings":["Division of Endocrinology, Kaiser Permanente of Georgia, Tucker, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Kaiser Permanente of Georgia, Tucker, Georgia","institution_ids":["https://openalex.org/I1343052199"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045442385","display_name":"Cheryl L. Jones","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cheryl L. Jones","raw_affiliation_strings":["Department of Biometry, University of Texas School of Public Health, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biometry, University of Texas School of Public Health, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042299275","display_name":"Barry R. Davis","orcid":"https://orcid.org/0000-0002-6943-5673","observed_orcids":["https://orcid.org/0000-0002-6943-5673"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry R. Davis","raw_affiliation_strings":["Department of Biometry, University of Texas School of Public Health, Houston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biometry, University of Texas School of Public Health, Houston, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056252103","display_name":"Jan Basile","orcid":"https://orcid.org/0000-0002-2302-7084","observed_orcids":["https://orcid.org/0000-0002-2302-7084"]},"institutions":[{"id":"https://openalex.org/I4210132004","display_name":"Ralph H. Johnson VA Medical Center","ror":"https://ror.org/030ma0n95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210131075","https://openalex.org/I4210132004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jan N. Basile","raw_affiliation_strings":["Department of Medicine, Ralph H. Johnson Veterans Administration Medical Center, Charleston, South Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Ralph H. Johnson Veterans Administration Medical Center, Charleston, South Carolina","institution_ids":["https://openalex.org/I4210132004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031644011","display_name":"David Calvin Goff","orcid":"https://orcid.org/0000-0001-7988-8361","observed_orcids":["https://orcid.org/0000-0001-7988-8361"]},"institutions":[{"id":"https://openalex.org/I4405269449","display_name":"Wake Forest University Health Sciences","ror":"https://ror.org/046r1r105","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]},{"id":"https://openalex.org/I47251452","display_name":"Wake Forest University","ror":"https://ror.org/0207ad724","country_code":"US","type":"education","lineage":["https://openalex.org/I47251452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David C. Goff","raw_affiliation_strings":["Public Health Sciences and Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Health Sciences and Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina","institution_ids":["https://openalex.org/I4405269449","https://openalex.org/I47251452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033334161","display_name":"Jerry O. Ciocon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108700","display_name":"Cleveland Clinic Florida","ror":"https://ror.org/0155k7414","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I4210108700"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jerry O. Ciocon","raw_affiliation_strings":["Geriatric Medicine Department, Cleveland Clinic Florida, Fort Lauderdale, Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric Medicine Department, Cleveland Clinic Florida, Fort Lauderdale, Florida","institution_ids":["https://openalex.org/I4210108700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111983252","display_name":"Mary Ellen Sweeney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152539","display_name":"Atlanta VA Medical Center","ror":"https://ror.org/04z89xx32","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210131075","https://openalex.org/I4210149289","https://openalex.org/I4210152539"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Ellen Sweeney","raw_affiliation_strings":["Department of Hypertension and Lipid Metabolism, Atlanta VA Medical Center, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hypertension and Lipid Metabolism, Atlanta VA Medical Center, Atlanta, Georgia","institution_ids":["https://openalex.org/I4210152539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038114801","display_name":"Otelio S. Randall","orcid":"https://orcid.org/0000-0003-3094-9420","observed_orcids":["https://orcid.org/0000-0003-3094-9420"]},"institutions":[{"id":"https://openalex.org/I137853757","display_name":"Howard University","ror":"https://ror.org/05gt1vc06","country_code":"US","type":"education","lineage":["https://openalex.org/I137853757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Otelio S. Randall","raw_affiliation_strings":["Division of Cardiovascular Diseases, Howard University, Washington, D.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases, Howard University, Washington, D.C","institution_ids":["https://openalex.org/I137853757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.5771,"has_fulltext":true,"cited_by_count":35,"citation_normalized_percentile":{"value":0.9478613,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"24","issue":"4","first_page":"654","last_page":"658"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.6830000281333923},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9210000038146973},{"id":"https://openalex.org/keywords/allhat-trial","display_name":"ALLHAT trial","score":0.7039999961853027},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.6589999794960022},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6899999976158142},{"id":"https://openalex.org/keywords/diuretic-therapy","display_name":"diuretic therapy","score":0.6380000114440918},{"id":"https://openalex.org/keywords/chlorthalidone","display_name":"chlorthalidone","score":0.9900000095367432},{"id":"https://openalex.org/keywords/amlodipine","display_name":"amlodipine","score":0.9829999804496765},{"id":"https://openalex.org/keywords/lisinopril","display_name":"lisinopril","score":1.0},{"id":"https://openalex.org/keywords/doxazosin","display_name":"doxazosin","score":1.0},{"id":"https://openalex.org/keywords/antihypertensive-therapy","display_name":"antihypertensive therapy","score":0.7839999794960022},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.6480000019073486},{"id":"https://openalex.org/keywords/baseline-characteristics","display_name":"baseline characteristics","score":0.6359999775886536},{"id":"https://openalex.org/keywords/african-american-patients","display_name":"African American patients","score":0.5049999952316284},{"id":"https://openalex.org/keywords/hispanic-patients","display_name":"Hispanic patients","score":0.9390000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9567784070968628},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6597496867179871},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6262922286987305},{"id":"https://openalex.org/C2779646130","wikidata":"https://www.wikidata.org/wiki/Q411347","display_name":"Amlodipine","level":3,"score":0.6103532314300537},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6003787517547607},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.596327543258667},{"id":"https://openalex.org/C2777880890","wikidata":"https://www.wikidata.org/wiki/Q412208","display_name":"Lisinopril","level":4,"score":0.554246187210083},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5390959978103638},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4985027313232422},{"id":"https://openalex.org/C2777590997","wikidata":"https://www.wikidata.org/wiki/Q419939","display_name":"Doxazosin","level":3,"score":0.49421337246894836},{"id":"https://openalex.org/C2778425758","wikidata":"https://www.wikidata.org/wiki/Q180762","display_name":"Angina","level":3,"score":0.4730868935585022},{"id":"https://openalex.org/C2780427769","wikidata":"https://www.wikidata.org/wiki/Q425289","display_name":"Chlorthalidone","level":3,"score":0.47193285822868347},{"id":"https://openalex.org/C2779918671","wikidata":"https://www.wikidata.org/wiki/Q200656","display_name":"Diuretic","level":2,"score":0.46883171796798706},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4574631154537201},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.45464712381362915},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.26860180497169495},{"id":"https://openalex.org/C27016395","wikidata":"https://www.wikidata.org/wiki/Q128861","display_name":"Angiotensin-converting enzyme","level":3,"score":0.17730841040611267},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.1375599503517151},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1317809522151947},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000317","descriptor_name":"Adrenergic alpha-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000317","descriptor_name":"Adrenergic alpha-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000317","descriptor_name":"Adrenergic alpha-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000959","descriptor_name":"Antihypertensive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002791","descriptor_name":"Cholesterol, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002791","descriptor_name":"Cholesterol, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002791","descriptor_name":"Cholesterol, Dietary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D003327","descriptor_name":"Coronary Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005006","descriptor_name":"Ethnicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017035","descriptor_name":"Pravastatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017035","descriptor_name":"Pravastatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017035","descriptor_name":"Pravastatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017292","descriptor_name":"Doxazosin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017292","descriptor_name":"Doxazosin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017292","descriptor_name":"Doxazosin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017311","descriptor_name":"Amlodipine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017311","descriptor_name":"Amlodipine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017311","descriptor_name":"Amlodipine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017706","descriptor_name":"Lisinopril","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017706","descriptor_name":"Lisinopril","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017706","descriptor_name":"Lisinopril","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D019161","descriptor_name":"Hydroxymethylglutaryl-CoA Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D044469","descriptor_name":"Racial Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044469","descriptor_name":"Racial Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044469","descriptor_name":"Racial Groups","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2337/diacare.24.4.654","doi":"https://doi.org/10.2337/diacare.24.4.654","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.654","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/654/587499/654.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},{"id":"pmid:11315826","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11315826","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes care","raw_type":"Clinical Trial"}],"best_oa_location":{"id":"doi:10.2337/diacare.24.4.654","doi":"https://doi.org/10.2337/diacare.24.4.654","is_oa":true,"landing_page_url":"https://doi.org/10.2337/diacare.24.4.654","pdf_url":"https://diabetesjournals.org/care/article-pdf/24/4/654/587499/654.pdf","source":{"id":"https://openalex.org/S49878492","display_name":"Diabetes Care","issn_l":"0149-5992","issn":["0149-5992","1935-5548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320274","host_organization_name":"American Diabetes Association","host_organization_lineage":["https://openalex.org/P4310320274"],"host_organization_lineage_names":["American Diabetes Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Care","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2004011968.pdf","grobid_xml":"https://content.openalex.org/works/W2004011968.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W4714463","https://openalex.org/W180946569","https://openalex.org/W1495650721","https://openalex.org/W1601936699","https://openalex.org/W1990084311","https://openalex.org/W1999904792","https://openalex.org/W2009438838","https://openalex.org/W2030350015","https://openalex.org/W2035885346","https://openalex.org/W2036529741","https://openalex.org/W2041663203","https://openalex.org/W2042539002","https://openalex.org/W2063130359","https://openalex.org/W2074108261","https://openalex.org/W2081593917","https://openalex.org/W2090202989","https://openalex.org/W2102979143","https://openalex.org/W2111596975","https://openalex.org/W2123036055","https://openalex.org/W2128864868","https://openalex.org/W2134270369","https://openalex.org/W2137408480","https://openalex.org/W2138119952","https://openalex.org/W2165817140","https://openalex.org/W2166089332","https://openalex.org/W2203067263","https://openalex.org/W2300192540","https://openalex.org/W2312999996","https://openalex.org/W2325609900","https://openalex.org/W2333063712","https://openalex.org/W2414167269","https://openalex.org/W2566199751","https://openalex.org/W2975364463","https://openalex.org/W3021438309","https://openalex.org/W4235435263","https://openalex.org/W4237577779","https://openalex.org/W4242344507","https://openalex.org/W4244643829","https://openalex.org/W4247347459","https://openalex.org/W4247891747","https://openalex.org/W4250583835","https://openalex.org/W4255609792","https://openalex.org/W4297972022","https://openalex.org/W6793995901"],"related_works":["https://openalex.org/W2145964826","https://openalex.org/W2588725266","https://openalex.org/W2028947900","https://openalex.org/W2413851649","https://openalex.org/W2154420335","https://openalex.org/W2076068521","https://openalex.org/W2071333973","https://openalex.org/W2138665521","https://openalex.org/W2003888948","https://openalex.org/W2166089332"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Hypertension":[1],"(HTN)":[2],"is":[3,18,143],"a":[4,37,48,126],"major":[5],"risk":[6,240],"factor":[7],"for":[8,212,241],"cardiovascular":[9,101],"disease":[10,97],"(CVD)":[11],"in":[12,63,160,221,235],"the":[13,34,59,64,89,161,166,187,197,213,231],"setting":[14,65],"of":[15,36,39,47,61,66,91,146,165,186,193,196,233],"diabetes.":[16,30,67],"There":[17,155],"no":[19],"consensus":[20],"on":[21],"how":[22],"best":[23],"to":[24,86,149,191,226],"treat":[25],"hypertension":[26,234],"among":[27],"those":[28,192],"with":[29,42,201],"Here":[31],"we":[32],"describe":[33],"characteristics":[35,185],"cohort":[38,188,220],"hypertensive":[40,77],"adults":[41],"diabetes":[43],"who":[44],"are":[45,156,173,176,180,189],"part":[46],"large":[49],"prospective":[50],"blood":[51],"pressure":[52],"study.":[53],"This":[54],"study":[55,163,215],"will":[56],"help":[57],"clarify":[58],"treatment":[60,120,232],"HTN":[62],"RESEARCH":[68],"DESIGN":[69],"AND":[70],"METHODS:":[71],"The":[72,140,203,218],"Antihypertensive":[73],"and":[74,93,99,104,114,121,135,178,183,208],"Lipid-Lowering":[75],"high-risk":[76],"participants,":[78],"ages":[79],">":[80],"or":[81],"=":[82],"55":[83],"years,":[84,148],"designed":[85],"determine":[87],"whether":[88],"incidence":[90],"fatal":[92],"nonfatal":[94,105],"coronary":[95],"heart":[96,112],"(CHD)":[98],"combined":[100],"events":[102],"(fatal":[103],"CHD,":[106],"revascularization":[107],"surgery,":[108],"angina":[109],"pectoris,":[110],"congestive":[111],"failure,":[113],"stroke)":[115],"differs":[116],"between":[117],"diuretic":[118],"(chlorthalidone)":[119],"three":[122],"alternative":[123],"antihypertensive":[124],"therapies:":[125],"calcium":[127],"channel":[128],"blocker":[129,138],"(amlodipine),":[130],"an":[131,136,144],"ACE":[132],"inhibitor":[133],"(lisinopril),":[134],"alpha-adrenergic":[137],"(doxazosin).":[139],"planned":[141],"follow-up":[142],"average":[145],"6":[147],"be":[150,224],"completed":[151],"March":[152],"2002.":[153],"RESULTS:":[154],"15,297":[157],"diabetic":[158,219,237],"individuals":[159],"ALLHAT":[162,222],"(36.0%":[164],"entire":[167],"cohort).":[168],"Of":[169],"these":[170],"individuals,":[171],"50.2%":[172],"male,":[174],"39.4%":[175],"African-American,":[177],"17.7%":[179],"Hispanic.":[181],"Demographic":[182],"laboratory":[184],"similar":[190],"other":[194],"studies":[195],"U.S.":[198],"elderly":[199],"population":[200],"HTN.":[202],"sample":[204],"size":[205],"has":[206],"42":[207],"93%":[209],"confidence,":[210],"treatments":[211],"two":[214],"outcomes.":[216],"CONCLUSIONS:":[217],"wil":[223],"able":[225],"provide":[227],"valuable":[228],"information":[229],"about":[230],"older":[236],"patients":[238],"at":[239],"incident":[242],"CVD.":[243]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}