{"id":"https://openalex.org/W2003887464","doi":"https://doi.org/10.1098/rspb.2000.1085","title":"Testosterone treatment is immunosuppressive in superb fairy\u2013wrens, yet free\u2013living males with high testosterone are more immunocompetent","display_name":"Testosterone treatment is immunosuppressive in superb fairy\u2013wrens, yet free\u2013living males with high testosterone are more immunocompetent","publication_year":2000,"publication_date":"2000-05-07","ids":{"openalex":"https://openalex.org/W2003887464","doi":"https://doi.org/10.1098/rspb.2000.1085","mag":"2003887464","pmid":"https://pubmed.ncbi.nlm.nih.gov/10853730","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1690613"},"language":"en","primary_location":{"id":"doi:10.1098/rspb.2000.1085","doi":"https://doi.org/10.1098/rspb.2000.1085","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rspb.2000.1085","pdf_url":null,"source":{"id":"https://openalex.org/S3006207977","display_name":"Proceedings of the Royal Society B Biological Sciences","issn_l":"0080-4649","issn":["0080-4649","0962-8452","1471-2954","2053-9193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Royal Society of London. Series B: Biological Sciences","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2003887464"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1690613/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043413628","display_name":"Anne Peters","orcid":"https://orcid.org/0000-0001-8071-0560","observed_orcids":["https://orcid.org/0000-0001-8071-0560"]},"institutions":[{"id":"https://openalex.org/I118347636","display_name":"Australian National University","ror":"https://ror.org/019wvm592","country_code":"AU","type":"education","lineage":["https://openalex.org/I118347636"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Anne Peters","raw_affiliation_strings":["Evolutionary Ecology Group, Division of Botany and Zoology, Australian National University, Canberra ACT 0200, Australia ()"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Evolutionary Ecology Group, Division of Botany and Zoology, Australian National University, Canberra ACT 0200, Australia ()","institution_ids":["https://openalex.org/I118347636"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043413628"],"corresponding_institution_ids":["https://openalex.org/I118347636"],"apc_list":null,"apc_paid":null,"fwci":16.398,"has_fulltext":false,"cited_by_count":268,"citation_normalized_percentile":{"value":0.99556919,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"267","issue":"1446","first_page":"883","last_page":"889"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10174","display_name":"Animal Behavior and Reproduction","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10174","display_name":"Animal Behavior and Reproduction","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11665","display_name":"Animal Vocal Communication and Behavior","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10089","display_name":"Avian ecology and behavior","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.8859999775886536},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9150000214576721},{"id":"https://openalex.org/keywords/immunocompetence-handicap-hypothesis","display_name":"immunocompetence handicap hypothesis","score":0.9279999732971191},{"id":"https://openalex.org/keywords/superb-fairy-wren","display_name":"superb fairy-wren","score":0.9300000071525574},{"id":"https://openalex.org/keywords/malurus-cyaneus","display_name":"Malurus cyaneus","score":0.9940000176429749},{"id":"https://openalex.org/keywords/sexual-signaling","display_name":"sexual signals","score":0.527999997138977},{"id":"https://openalex.org/keywords/antibody-response","display_name":"antibody response","score":0.5350000262260437},{"id":"https://openalex.org/keywords/nuptial-plumage","display_name":"nuptial plumage","score":0.7900000214576721},{"id":"https://openalex.org/keywords/molting","display_name":"molting","score":0.828000009059906},{"id":"https://openalex.org/keywords/intersexual-selection","display_name":"intersexual selection","score":0.7239999771118164},{"id":"https://openalex.org/keywords/humoral-immunity","display_name":"humoral immunity","score":0.7590000033378601},{"id":"https://openalex.org/keywords/phenotypic-quality","display_name":"phenotypic quality","score":0.6179999709129333}],"concepts":[{"id":"https://openalex.org/C2779594111","wikidata":"https://www.wikidata.org/wiki/Q3303665","display_name":"Plumage","level":2,"score":0.899452805519104},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.8612625598907471},{"id":"https://openalex.org/C2777422395","wikidata":"https://www.wikidata.org/wiki/Q3149136","display_name":"Immunocompetence","level":3,"score":0.7852765917778015},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7802144289016724},{"id":"https://openalex.org/C41905685","wikidata":"https://www.wikidata.org/wiki/Q381084","display_name":"Moulting","level":3,"score":0.5190761685371399},{"id":"https://openalex.org/C2776787076","wikidata":"https://www.wikidata.org/wiki/Q2920296","display_name":"Captivity","level":2,"score":0.5111919045448303},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44780102372169495},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4021183252334595},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.34071287512779236},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.23935163021087646},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.18961456418037415},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.09320789575576782},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07384836673736572},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007114","descriptor_name":"Immunization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007121","descriptor_name":"Immunocompetence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012726","descriptor_name":"Sexual Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020308","descriptor_name":"Songbirds","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D020308","descriptor_name":"Songbirds","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1098/rspb.2000.1085","doi":"https://doi.org/10.1098/rspb.2000.1085","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rspb.2000.1085","pdf_url":null,"source":{"id":"https://openalex.org/S3006207977","display_name":"Proceedings of the Royal Society B Biological Sciences","issn_l":"0080-4649","issn":["0080-4649","0962-8452","1471-2954","2053-9193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Royal Society of London. Series B: Biological Sciences","raw_type":"journal-article"},{"id":"pmid:10853730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10853730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. Biological sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1690613","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1690613/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Biol Sci","raw_type":"Text"},{"id":"pmh:oai:openresearch-repository.anu.edu.au:1885/89233","doi":null,"is_oa":false,"landing_page_url":"https://openresearch-repository.anu.edu.au/items/e92365bd-fe77-4e61-83a0-a688f7f61522/request-a-copy?bitstream=cc8c61bf-13fc-4a2b-a85e-b054dcb362ca","pdf_url":null,"source":{"id":"https://openalex.org/S4306402539","display_name":"ANU Open Research (Australian National University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118347636","host_organization_name":"Australian National University","host_organization_lineage":["https://openalex.org/I118347636"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the Royal Society of London Series B: Biological Sciences","raw_type":"Journal article"},{"id":"pmh:oai:escidoc.org:escidoc:2327918","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002B-1E47-1","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210088280","host_organization_name":"Max Planck Digital Library","host_organization_lineage":["https://openalex.org/I4210088280"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.mpg.de:item_2327918","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-002B-1E47-1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proceedings of the Royal Society B: Biological Sciences","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1690613","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1690613/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Biol Sci","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1968570718","https://openalex.org/W1974533368","https://openalex.org/W1985626518","https://openalex.org/W1988867811","https://openalex.org/W1990735694","https://openalex.org/W1991945930","https://openalex.org/W1997315390","https://openalex.org/W2005022192","https://openalex.org/W2012169853","https://openalex.org/W2027586930","https://openalex.org/W2045587537","https://openalex.org/W2052735134","https://openalex.org/W2058109426","https://openalex.org/W2058561523","https://openalex.org/W2059838988","https://openalex.org/W2067482350","https://openalex.org/W2069247969","https://openalex.org/W2078121933","https://openalex.org/W2080260687","https://openalex.org/W2084332918","https://openalex.org/W2084718508","https://openalex.org/W2122929839","https://openalex.org/W2124590824","https://openalex.org/W2133417675","https://openalex.org/W2148110689","https://openalex.org/W2150826881","https://openalex.org/W2165091688","https://openalex.org/W2316063032","https://openalex.org/W2896817248","https://openalex.org/W4231600642"],"related_works":["https://openalex.org/W2148110689","https://openalex.org/W7097310868","https://openalex.org/W2111254984","https://openalex.org/W2168200838","https://openalex.org/W2114637576","https://openalex.org/W2068495948","https://openalex.org/W2136096269","https://openalex.org/W2060348119","https://openalex.org/W2144433850","https://openalex.org/W2089762154"],"abstract_inverted_index":{"The":[0,163],"immunocompetence":[1,41,167],"handicap":[2],"hypothesis":[3],"proposes":[4],"that":[5,27],"the":[6,38,63,76,121,139,185],"immunosuppressive":[7,30,170],"effect":[8],"of":[9,13,100,123],"testosterone":[10,28,43,60,107,119,146,161,171,204],"enforces":[11],"honesty":[12],"sexual":[14],"signalling":[15],"via":[16],"a":[17,49,98],"physiological":[18],"trade-off":[19],"between":[20,40,165],"signal":[21],"intensity":[22],"and":[23,42,59,91,96,105,112,142,168,214],"immunocompetence.":[24],"However,":[25],"evidence":[26],"is":[29,31,205],"scant,":[32],"particularly":[33,201],"in":[34,44,88,94,113,129,156],"birds.":[35,131],"I":[36,74],"studied":[37],"correlation":[39],"superb":[45],"fairy-wrens":[46],"(Malurus":[47],"cyaneus),":[48],"species":[50],"with":[51,82,103,118,159,179],"intense":[52],"intersexual":[53],"selection.":[54],"Males":[55],"are":[56,176],"seasonally":[57],"dichromatic":[58],"increases":[61],"during":[62],"moult":[64],"from":[65],"dull":[66],"brown":[67],"eclipse":[68,109,157],"plumage":[69,141,158],"into":[70],"bright":[71],"nuptial":[72,114,140],"plumage.":[73],"determined":[75],"primary":[77],"antibody":[78,125],"response":[79,126],"to":[80,127,150,152,207],"immunization":[81],"sheep":[83],"red":[84],"blood":[85],"cells":[86],"(SRBCs)":[87],"(i)":[89],"control":[90],"testosterone-implanted":[92],"males":[93,102,135,155,190],"captivity,":[95],"(ii)":[97],"cross-section":[99],"free-living":[101,134],"basal":[104,160],"elevated":[106,145],"(in":[108],"plumage,":[110],"moulting":[111,213],"plumage).":[115],"Experimental":[116],"treatment":[117],"decreased":[120],"likelihood":[122],"an":[124],"SRBCs":[128,153],"captive":[130],"In":[132,183],"contrast,":[133],"which":[136],"had":[137,143],"acquired":[138],"naturally":[144],"were":[147],"more":[148],"likely":[149],"respond":[151],"than":[154],"levels.":[162],"association":[164,186],"higher":[166,169],"could":[172,187],"arise":[173],"if":[174,189],"both":[175],"positively":[177],"correlated":[178],"male":[180],"phenotypic":[181],"quality":[182],"addition,":[184],"result":[188],"compensate":[191],"for":[192],"potential":[193],"immunosuppression":[194],"by":[195],"enhancing":[196],"their":[197],"humoral":[198],"immune":[199],"responses,":[200],"since":[202],"high":[203],"linked":[206],"other":[208],"demanding":[209],"activities":[210],"such":[211],"as":[212],"courtship":[215],"displays.":[216]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}