{"id":"https://openalex.org/W2003855700","doi":"https://doi.org/10.1001/archopht.1957.00940010035004","title":"The Effect of Age upon Lens Metabolism","display_name":"The Effect of Age upon Lens Metabolism","publication_year":1957,"publication_date":"1957-07-01","ids":{"openalex":"https://openalex.org/W2003855700","doi":"https://doi.org/10.1001/archopht.1957.00940010035004","mag":"2003855700","pmid":"https://pubmed.ncbi.nlm.nih.gov/13434536"},"language":"en","primary_location":{"id":"doi:10.1001/archopht.1957.00940010035004","doi":"https://doi.org/10.1001/archopht.1957.00940010035004","is_oa":false,"landing_page_url":"https://doi.org/10.1001/archopht.1957.00940010035004","pdf_url":null,"source":{"id":"https://openalex.org/S80523760","display_name":"Archives of Ophthalmology","issn_l":"0003-9950","issn":["0003-9950","1538-3601"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"H. GREEN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. GREEN","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110000138","display_name":"S. A. SOLOMON","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. A. SOLOMON","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4047,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.77890521,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"58","issue":"1","first_page":"23","last_page":"36"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.6987000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11291","display_name":"Intraocular Surgery and Lenses","score":0.27000001072883606,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lens-metabolism","display_name":"lens metabolism","score":0.7889999747276306},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.8339999914169312},{"id":"https://openalex.org/keywords/age-related-cataract","display_name":"senile cataract","score":0.9819999933242798},{"id":"https://openalex.org/keywords/lens-opacification","display_name":"lens opacification","score":0.7649999856948853},{"id":"https://openalex.org/keywords/aqueous-humor","display_name":"aqueous humor","score":0.8769999742507935},{"id":"https://openalex.org/keywords/lens-growth","display_name":"lens growth","score":0.6359999775886536},{"id":"https://openalex.org/keywords/cataract-pathogenesis","display_name":"cataract pathogenesis","score":0.859000027179718}],"concepts":[{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.6323012113571167},{"id":"https://openalex.org/C15336307","wikidata":"https://www.wikidata.org/wiki/Q1766051","display_name":"Lens (geology)","level":2,"score":0.5979341864585876},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.41078561544418335},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3953942656517029},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.352841317653656},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2737087905406952},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2667655944824219},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D007887","descriptor_name":"Fabaceae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007908","descriptor_name":"Lens, Crystalline","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007909","descriptor_name":"Lenses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1001/archopht.1957.00940010035004","doi":"https://doi.org/10.1001/archopht.1957.00940010035004","is_oa":false,"landing_page_url":"https://doi.org/10.1001/archopht.1957.00940010035004","pdf_url":null,"source":{"id":"https://openalex.org/S80523760","display_name":"Archives of Ophthalmology","issn_l":"0003-9950","issn":["0003-9950","1538-3601"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Archives of Ophthalmology","raw_type":"journal-article"},{"id":"pmid:13434536","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/13434536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"A.M.A. archives of ophthalmology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, justice, and strong institutions"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W197951560","https://openalex.org/W1535643256","https://openalex.org/W1588180482","https://openalex.org/W1600775218","https://openalex.org/W2012718878","https://openalex.org/W2153435210"],"related_works":["https://openalex.org/W2394837942","https://openalex.org/W183949612","https://openalex.org/W200277955","https://openalex.org/W2415787739","https://openalex.org/W2441128486","https://openalex.org/W1979290229","https://openalex.org/W2438954070","https://openalex.org/W4254240089","https://openalex.org/W2333035725","https://openalex.org/W1976948875"],"abstract_inverted_index":{"Perhaps":[0],"the":[1,26,45,48,64,94,124],"most":[2],"common":[3],"type":[4],"of":[5,11,25,47,77,93,126,128],"ocular":[6],"ailment":[7],"resulting":[8],"in":[9,14,44],"diminution":[10],"visual":[12],"acuity":[13],"older":[15],"persons":[16],"is":[17,51,61,70,96,110,121,131],"senile":[18],"cataract,":[19],"a":[20,40],"condition":[21],"characterized":[22],"by":[23,63],"opacification":[24],"normally":[27,97],"transparent":[28],"lens":[29,38,95,130],"without":[30],"any":[31],"direct":[32],"local":[33],"or":[34],"constitutional":[35],"cause.":[36],"The":[37,91],"occupies":[39],"very":[41],"unique":[42],"position":[43],"economy":[46],"body.":[49],"It":[50],"entirely":[52],"self-contained,":[53],"having":[54],"neither":[55],"vascular":[56],"nor":[57],"nervous":[58],"connections,":[59],"and":[60,84,106,137],"surrounded":[62],"aqueous":[65],"humor,":[66],"on":[67],"which":[68,81],"it":[69],"almost":[71],"wholly":[72],"dependent":[73],"for":[74],"those":[75],"processes":[76],"metabolic":[78],"exchange":[79],"with":[80,144],"its":[82,107],"vitality":[83],"continuing":[85],"clarity":[86],"are":[87],"so":[88],"intimately":[89],"connected.":[90],"growth":[92],"continuous":[98],"from":[99],"early":[100],"fetal":[101],"life":[102],"until":[103],"somatic":[104],"death":[105],"crystal":[108],"clearness":[109],"maintained":[111],"normally.":[112],"Many":[113],"theories":[114],"have":[115],"been":[116],"advanced":[117],"but":[118],"relatively":[119],"little":[120],"known":[122],"concerning":[123],"mechanism":[125],"pathogenesis":[127],"cataract.1,2The":[129],"considered":[132],"to":[133,135,139],"grow":[134],"maturity":[136],"then":[138],"undergo":[140],"physicochemical":[141],"changes":[142],"associated":[143],"senescence.":[145],"These":[146],"include":[147]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}