{"id":"https://openalex.org/W2003751712","doi":"https://doi.org/10.1016/0165-5728(89)90056-8","title":"Suppressive activity of long-term myelin basic protein-specific SJL T cell lines","display_name":"Suppressive activity of long-term myelin basic protein-specific SJL T cell lines","publication_year":1989,"publication_date":"1989-08-01","ids":{"openalex":"https://openalex.org/W2003751712","doi":"https://doi.org/10.1016/0165-5728(89)90056-8","mag":"2003751712","pmid":"https://pubmed.ncbi.nlm.nih.gov/2473998"},"language":"en","primary_location":{"id":"doi:10.1016/0165-5728(89)90056-8","doi":"https://doi.org/10.1016/0165-5728(89)90056-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-5728(89)90056-8","pdf_url":null,"source":{"id":"https://openalex.org/S137419829","display_name":"Journal of Neuroimmunology","issn_l":"0165-5728","issn":["0165-5728","1872-8421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroimmunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088076344","display_name":"M.Elena Barzaga-Gilbert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.Elena Barzaga-Gilbert","raw_affiliation_strings":["Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067448158","display_name":"Marianne J. Skeen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marianne J. Skeen","raw_affiliation_strings":["Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108368735","display_name":"C.-H. Jen Chou","orcid":"https://orcid.org/0009-0008-2572-5485","observed_orcids":["https://orcid.org/0009-0008-2572-5485"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.-H.J. Chou","raw_affiliation_strings":["Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113538433","display_name":"Robert B. Fritz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert B. Fritz","raw_affiliation_strings":["Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, U.S.A","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":1.1462,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.77581212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"3","first_page":"241","last_page":"247"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.6068999767303467,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.6068999767303467,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.3815999925136566,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelin-basic-protein","display_name":"myelin basic protein","score":0.9430000185966492},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.7059999704360962},{"id":"https://openalex.org/keywords/experimental-autoimmune-encephalomyelitis","display_name":"experimental autoimmune encephalomyelitis","score":0.9490000009536743},{"id":"https://openalex.org/keywords/sjl-mice","display_name":"SJL mice","score":0.8960000276565552},{"id":"https://openalex.org/keywords/t-cell-co-culture","display_name":"T cell co-culture","score":0.6940000057220459},{"id":"https://openalex.org/keywords/adoptive-transfer","display_name":"adoptive transfer","score":0.906000018119812},{"id":"https://openalex.org/keywords/t-cell-proliferation-inhibition","display_name":"T cell proliferation inhibition","score":0.7239999771118164},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.7390000224113464},{"id":"https://openalex.org/keywords/tumor-necrosis-factor-beta","display_name":"lymphotoxin","score":0.9800000190734863},{"id":"https://openalex.org/keywords/prostaglandins","display_name":"prostaglandins","score":0.9700000286102295}],"concepts":[{"id":"https://openalex.org/C2780876595","wikidata":"https://www.wikidata.org/wiki/Q410974","display_name":"Myelin basic protein","level":4,"score":0.7879780530929565},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.6839284896850586},{"id":"https://openalex.org/C90375314","wikidata":"https://www.wikidata.org/wiki/Q3537484","display_name":"Adoptive cell transfer","level":4,"score":0.6301825046539307},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5525574088096619},{"id":"https://openalex.org/C2781017270","wikidata":"https://www.wikidata.org/wiki/Q2756638","display_name":"Galactocerebroside","level":5,"score":0.5431763529777527},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5300946831703186},{"id":"https://openalex.org/C2778486448","wikidata":"https://www.wikidata.org/wiki/Q494066","display_name":"Experimental autoimmune encephalomyelitis","level":3,"score":0.5160970091819763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5103158354759216},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.4818469285964966},{"id":"https://openalex.org/C2777899865","wikidata":"https://www.wikidata.org/wiki/Q1634879","display_name":"Encephalomyelitis","level":3,"score":0.4394034147262573},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4350094795227051},{"id":"https://openalex.org/C73588182","wikidata":"https://www.wikidata.org/wiki/Q2663023","display_name":"Cytolysis","level":4,"score":0.43342751264572144},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42053499817848206},{"id":"https://openalex.org/C2776985911","wikidata":"https://www.wikidata.org/wiki/Q916698","display_name":"Oligodendrocyte","level":4,"score":0.29558804631233215},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.2326917052268982},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.1531236171722412},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.1509430706501007},{"id":"https://openalex.org/C2780640218","wikidata":"https://www.wikidata.org/wiki/Q8277","display_name":"Multiple sclerosis","level":2,"score":0.12531310319900513},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1000438928604126},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09353658556938171},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004676","descriptor_name":"Myelin Basic Protein","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004681","descriptor_name":"Encephalomyelitis, Autoimmune, Experimental","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0165-5728(89)90056-8","doi":"https://doi.org/10.1016/0165-5728(89)90056-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0165-5728(89)90056-8","pdf_url":null,"source":{"id":"https://openalex.org/S137419829","display_name":"Journal of Neuroimmunology","issn_l":"0165-5728","issn":["0165-5728","1872-8421"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neuroimmunology","raw_type":"journal-article"},{"id":"pmid:2473998","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2473998","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neuroimmunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2046473211","display_name":null,"funder_award_id":"NS10721","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1503094954","https://openalex.org/W1504285588","https://openalex.org/W1512091369","https://openalex.org/W1528730409","https://openalex.org/W1535663915","https://openalex.org/W1554708598","https://openalex.org/W1760370576","https://openalex.org/W1782640926","https://openalex.org/W1818355503","https://openalex.org/W1832527043","https://openalex.org/W1926067995","https://openalex.org/W1982021670","https://openalex.org/W1994994439","https://openalex.org/W2044578153","https://openalex.org/W2057123987","https://openalex.org/W2057715643","https://openalex.org/W2072842550","https://openalex.org/W2077257956","https://openalex.org/W2090456637","https://openalex.org/W2092621634","https://openalex.org/W2127534922","https://openalex.org/W2142320812","https://openalex.org/W2409914144","https://openalex.org/W2412334361","https://openalex.org/W2412981086"],"related_works":["https://openalex.org/W2042268869","https://openalex.org/W2092359075","https://openalex.org/W2040360711","https://openalex.org/W1968098231","https://openalex.org/W2077257956","https://openalex.org/W2058032864","https://openalex.org/W2095156247","https://openalex.org/W1506050835","https://openalex.org/W2044578153","https://openalex.org/W2001782625"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}