{"id":"https://openalex.org/W2003702181","doi":"https://doi.org/10.1016/j.bpj.2011.11.3303","title":"Structure, Dynamics, and Mechanism of the Leucine Transporter Studied by Double Electron Electron Resonance Spectroscopy","display_name":"Structure, Dynamics, and Mechanism of the Leucine Transporter Studied by Double Electron Electron Resonance Spectroscopy","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2003702181","doi":"https://doi.org/10.1016/j.bpj.2011.11.3303","mag":"2003702181"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2011.11.3303","doi":"https://doi.org/10.1016/j.bpj.2011.11.3303","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.3303","pdf_url":"http://www.cell.com/article/S0006349511046510/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349511046510/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014782045","display_name":"Kelli N. Kazmier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelli Kazmier","raw_affiliation_strings":["Vanderbilt University, Nashville, TN, USA","Vanderbilt University Nashville TN USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt University Nashville TN USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028560103","display_name":"Matthias Quick","orcid":"https://orcid.org/0000-0002-8620-827X","observed_orcids":["https://orcid.org/0000-0002-8620-827X"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthias Quick","raw_affiliation_strings":["Columbia University College of Physicians and Surgeons, New York, NY, USA","Columbia University College of Physicians & Surgeons , New York, NY , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University College of Physicians and Surgeons, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University College of Physicians & Surgeons , New York, NY , USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025947629","display_name":"Lei Shi","orcid":"https://orcid.org/0000-0002-4137-096X","observed_orcids":["https://orcid.org/0000-0002-4137-096X"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lei Shi","raw_affiliation_strings":["Weill Medical College of Cornell University, New York, NY, USA","Weill Medical College of Cornell University New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Medical College of Cornell University, New York, NY, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Weill Medical College of Cornell University New York, NY, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014370221","display_name":"Harel Weinstein","orcid":"https://orcid.org/0000-0003-3473-9818","observed_orcids":["https://orcid.org/0000-0003-3473-9818"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harel Weinstein","raw_affiliation_strings":["Weill Medical College of Cornell University, New York, NY, USA","Weill Medical College of Cornell University New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Weill Medical College of Cornell University, New York, NY, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Weill Medical College of Cornell University New York, NY, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076865147","display_name":"Jonathan A. Javitch","orcid":"https://orcid.org/0000-0001-7395-2967","observed_orcids":["https://orcid.org/0000-0001-7395-2967"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan A. Javitch","raw_affiliation_strings":["Columbia University College of Physicians and Surgeons, New York, NY, USA","Columbia University College of Physicians & Surgeons , New York, NY , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Columbia University College of Physicians and Surgeons, New York, NY, USA","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Columbia University College of Physicians & Surgeons , New York, NY , USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059881003","display_name":"Hassane S. Mchaourab","orcid":"https://orcid.org/0000-0002-5673-0980","observed_orcids":["https://orcid.org/0000-0002-5673-0980"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hassane S. Mchaourab","raw_affiliation_strings":["Vanderbilt University, Nashville, TN, USA","Vanderbilt University Nashville TN USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Vanderbilt University Nashville TN USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1180203,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"102","issue":"3","first_page":"606a","last_page":"606a"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12381","display_name":"Electron Spin Resonance Studies","score":0.4860999882221222,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12381","display_name":"Electron Spin Resonance Studies","score":0.4860999882221222,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.2874000072479248,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.06809999793767929,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leut","display_name":"LeuT","score":0.9900000095367432},{"id":"https://openalex.org/keywords/neurotransmitter-sodium-symporters","display_name":"neurotransmitter:sodium symporters","score":0.925000011920929},{"id":"https://openalex.org/keywords/intracellular-dynamics","display_name":"intracellular dynamics","score":0.6959999799728394},{"id":"https://openalex.org/keywords/double-electron-electron-resonance","display_name":"double electron-electron resonance","score":0.7300000190734863},{"id":"https://openalex.org/keywords/distance-distribution","display_name":"distance distribution","score":0.7149999737739563},{"id":"https://openalex.org/keywords/dopamine-transporter","display_name":"dopamine transporter","score":0.5720000267028809},{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.9509999752044678},{"id":"https://openalex.org/keywords/norepinephrine-transporter","display_name":"norepinephrine transporter","score":0.9860000014305115},{"id":"https://openalex.org/keywords/neurotransmitter-reuptake","display_name":"neurotransmitter reuptake","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C2993285035","wikidata":"https://www.wikidata.org/wiki/Q2643251","display_name":"Synaptic cleft","level":4,"score":0.7341723442077637},{"id":"https://openalex.org/C99631742","wikidata":"https://www.wikidata.org/wiki/Q22290476","display_name":"Reuptake","level":4,"score":0.6349760293960571},{"id":"https://openalex.org/C16696662","wikidata":"https://www.wikidata.org/wiki/Q17079236","display_name":"Neurotransmitter transporter","level":4,"score":0.5638086199760437},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.5492883920669556},{"id":"https://openalex.org/C120405084","wikidata":"https://www.wikidata.org/wiki/Q285307","display_name":"Symporter","level":4,"score":0.5070044994354248},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4698454737663269},{"id":"https://openalex.org/C2779097318","wikidata":"https://www.wikidata.org/wiki/Q2993446","display_name":"Connectomics","level":4,"score":0.4443700313568115},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.4145594835281372},{"id":"https://openalex.org/C2776219046","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter","level":3,"score":0.41160643100738525},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3892000615596771},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.26556396484375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1786164939403534},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17155319452285767},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.14353108406066895},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.14058253169059753},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11981502175331116},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08699223399162292},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bpj.2011.11.3303","doi":"https://doi.org/10.1016/j.bpj.2011.11.3303","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.3303","pdf_url":"http://www.cell.com/article/S0006349511046510/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2011.11.3303","doi":"https://doi.org/10.1016/j.bpj.2011.11.3303","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2011.11.3303","pdf_url":"http://www.cell.com/article/S0006349511046510/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8500000238418579}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2003702181.pdf"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W2170737085"],"related_works":["https://openalex.org/W1512819039","https://openalex.org/W1579298346","https://openalex.org/W2516337184","https://openalex.org/W2568664960","https://openalex.org/W2049695640","https://openalex.org/W4225371759","https://openalex.org/W2088607649","https://openalex.org/W4319936545","https://openalex.org/W2526617467","https://openalex.org/W2600839259"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-10-10T00:00:00"}