{"id":"https://openalex.org/W200364192","doi":null,"title":"PROGRESS IN CHEMOTHERAPY OF CANCER.","display_name":"PROGRESS IN CHEMOTHERAPY OF CANCER.","publication_year":1964,"publication_date":"1964-01-01","ids":{"openalex":"https://openalex.org/W200364192","mag":"200364192","pmid":"https://pubmed.ncbi.nlm.nih.gov/14163957","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2554827"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:1449103","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2554827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/articles/PMC2554827","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"W DAVIS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W DAVIS","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058565751","display_name":"Larionov Lf","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L F LARIONOV","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2128,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.44095997,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"30","issue":null,"first_page":"327","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.8935999870300293,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11845","display_name":"Cancer therapeutics and mechanisms","score":0.8935999870300293,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14275","display_name":"Historical Medical Research and Treatments","score":0.030700000002980232,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13123","display_name":"Advances in Oncology and Radiotherapy","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-chemotherapy","display_name":"cancer chemotherapy","score":0.9819999933242798},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.8769999742507935},{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"mechanism of action","score":0.8240000009536743},{"id":"https://openalex.org/keywords/drug-screening","display_name":"drug screening","score":0.6179999709129333},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.9350000023841858},{"id":"https://openalex.org/keywords/drug-administration-methods","display_name":"drug administration methods","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7379791736602783},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.6858148574829102},{"id":"https://openalex.org/C2983288658","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Cancer chemotherapy","level":3,"score":0.5753459334373474},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5032119154930115},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.48949968814849854},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.48800554871559143},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.42770880460739136},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3535217046737671},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2694457173347473},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2109200656414032},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15779629349708557}],"mesh":[{"descriptor_ui":"D000470","descriptor_name":"Alkaloids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000904","descriptor_name":"Antibiotics, Antitubercular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000963","descriptor_name":"Antimetabolites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001681","descriptor_name":"Biological Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004938","descriptor_name":"Esophageal Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006728","descriptor_name":"Hormones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007116","descriptor_name":"Immunization, Passive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D010478","descriptor_name":"Chemotherapy, Cancer, Regional Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013514","descriptor_name":"Surgical Procedures, Operative","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:1449103","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2554827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:14163957","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14163957","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the World Health Organization","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2554827","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2554827/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bull World Health Organ","raw_type":"Text"},{"id":"mag:200364192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14163957","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1449103","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC2554827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1575767883","https://openalex.org/W1610650548","https://openalex.org/W1968418654","https://openalex.org/W1984444308","https://openalex.org/W1988210681","https://openalex.org/W2004322406","https://openalex.org/W2008373064","https://openalex.org/W2028079563","https://openalex.org/W2036675949","https://openalex.org/W2038839277","https://openalex.org/W2058784129","https://openalex.org/W2064488813","https://openalex.org/W2075425214","https://openalex.org/W2077604799","https://openalex.org/W2087739913","https://openalex.org/W2094070344","https://openalex.org/W2096548608","https://openalex.org/W2127197372","https://openalex.org/W2140853505","https://openalex.org/W2217868600","https://openalex.org/W2312553740","https://openalex.org/W2313427550","https://openalex.org/W2314700195","https://openalex.org/W2315015442","https://openalex.org/W2315503465","https://openalex.org/W2316087895","https://openalex.org/W2319696837","https://openalex.org/W2321597988","https://openalex.org/W2321961173","https://openalex.org/W2322193834","https://openalex.org/W2323953020","https://openalex.org/W2324637137","https://openalex.org/W2325958627","https://openalex.org/W2326104828","https://openalex.org/W2326106965","https://openalex.org/W2328102977","https://openalex.org/W2328635237","https://openalex.org/W2329473221","https://openalex.org/W2329586394","https://openalex.org/W2329725699","https://openalex.org/W2331977947","https://openalex.org/W2332711164","https://openalex.org/W2334490266","https://openalex.org/W2398593920","https://openalex.org/W2404219641","https://openalex.org/W2409209418","https://openalex.org/W2427086263","https://openalex.org/W2461229379"],"related_works":["https://openalex.org/W4230293270","https://openalex.org/W3129379715","https://openalex.org/W53903909","https://openalex.org/W2412630427","https://openalex.org/W613310956","https://openalex.org/W4230827926","https://openalex.org/W1489865395","https://openalex.org/W105887364","https://openalex.org/W4245808893","https://openalex.org/W118572239"],"abstract_inverted_index":{"The":[0,40,62],"chemotherapy":[1],"of":[2,14,33,42,66,68,85,130],"cancer,":[3],"in":[4,21,37,51,128,138],"relation":[5],"to":[6,57],"surgery":[7],"and":[8,48,64,74,80,90,117],"radiotherapy,":[9],"is":[10],"a":[11,58,81],"new":[12,112,134],"method":[13],"attack.":[15],"Its":[16],"development,":[17],"which":[18,94],"started":[19],"virtually":[20],"the":[22,27,43,69,86,91,99,106,139],"1940's,":[23],"was":[24,83,108],"reviewed":[25],"by":[26],"WHO":[28],"Expert":[29],"Committee":[30,44],"on":[31],"Chemotherapy":[32],"Cancer":[34],"that":[35,102],"met":[36],"September":[38],"1961.":[39],"report":[41,107],"dealt":[45],"with":[46],"experimental":[47],"clinical":[49,76,121],"studies":[50],"this":[52],"field":[53],"critically,":[54],"but":[55],"also":[56],"necessary":[59],"degree,":[60],"comprehensively.":[61],"design":[63],"mechanism":[65],"action":[67],"drugs,":[70],"their":[71],"biological":[72],"screening":[73],"subsequent":[75],"trials":[77],"were":[78,96],"discussed,":[79],"review":[82],"presented":[84],"clinically":[87],"available":[88],"drugs":[89],"neoplasms":[92],"for":[93],"they":[95],"indicated.":[97],"In":[98],"two":[100],"years":[101],"have":[103,114,119,124],"elapsed":[104],"since":[105],"drawn":[109],"up":[110],"many":[111],"compounds":[113],"been":[115,125],"tested":[116],"some":[118],"had":[120],"trials.":[122],"There":[123],"developments,":[126],"too,":[127],"methods":[129],"administration.":[131],"All":[132],"these":[133],"developments":[135],"are":[136],"discussed":[137],"present":[140],"paper.":[141]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}