{"id":"https://openalex.org/W2003557005","doi":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","title":"Occurrence and characteristics of hypodense eosinophils in rats infected with Trichinella spiralis","display_name":"Occurrence and characteristics of hypodense eosinophils in rats infected with Trichinella spiralis","publication_year":1992,"publication_date":"1992-09-01","ids":{"openalex":"https://openalex.org/W2003557005","doi":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","mag":"2003557005","pmid":"https://pubmed.ncbi.nlm.nih.gov/1437239"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-3024.1992.tb00024.x","doi":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","pdf_url":null,"source":{"id":"https://openalex.org/S80886111","display_name":"Parasite Immunology","issn_l":"0141-9838","issn":["0141-9838","1365-3024"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasite Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073085752","display_name":"Atsuo Hamada","orcid":"https://orcid.org/0000-0002-0481-9959","observed_orcids":["https://orcid.org/0000-0002-0481-9959"]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"ATSUO HAMADA","raw_affiliation_strings":["Department of Parasitology, Jikei University School of Medicine, Tokyo, Japan","Department of Parasitology, Jikei University School of Medicine, 3\u201025\u20108 Nishishinbashi, Minatoku, Tokyo 105. Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Jikei University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I115498069"]},{"raw_affiliation_string":"Department of Parasitology, Jikei University School of Medicine, 3\u201025\u20108 Nishishinbashi, Minatoku, Tokyo 105. Japan","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112470169","display_name":"Naohiro Watanabe","orcid":"https://orcid.org/0009-0009-8206-6399","observed_orcids":["https://orcid.org/0009-0009-8206-6399"]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"NAOHIRO WATANABE","raw_affiliation_strings":["Department of Parasitology, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minatoku, Tokyo 105. Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minatoku, Tokyo 105. Japan","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"last","author":{"id":null,"display_name":"AKIO KOBAYASHI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"AKIO KOBAYASHI","raw_affiliation_strings":["Department of Parasitology, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minatoku, Tokyo 105. Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minatoku, Tokyo 105. Japan","institution_ids":["https://openalex.org/I115498069"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5073085752"],"corresponding_institution_ids":["https://openalex.org/I115498069"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":0.3629,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.63450292,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"5","first_page":"503","last_page":"512"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12600","display_name":"Eosinophilic Disorders and Syndromes","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypodense-eosinophils","display_name":"hypodense eosinophils","score":0.9890000224113464},{"id":"https://openalex.org/keywords/eosinophil-density","display_name":"eosinophil density","score":0.8510000109672546},{"id":"https://openalex.org/keywords/trichinella-spiralis","display_name":"Trichinella spiralis","score":0.9629999995231628},{"id":"https://openalex.org/keywords/trichinellosis","display_name":"trichinellosis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/eosinophilia","display_name":"eosinophilia","score":0.8450000286102295},{"id":"https://openalex.org/keywords/helminth-infection","display_name":"helminthiasis","score":0.9259999990463257},{"id":"https://openalex.org/keywords/peritoneal-fluid","display_name":"peritoneal fluid","score":0.9480000138282776},{"id":"https://openalex.org/keywords/eosinophil-cytotoxicity","display_name":"eosinophil cytotoxicity","score":0.7639999985694885},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C2781320125","wikidata":"https://www.wikidata.org/wiki/Q730937","display_name":"Trichinella spiralis","level":3,"score":0.9344464540481567},{"id":"https://openalex.org/C2777129736","wikidata":"https://www.wikidata.org/wiki/Q505142","display_name":"Eosinophilia","level":2,"score":0.9095081090927124},{"id":"https://openalex.org/C2777037409","wikidata":"https://www.wikidata.org/wiki/Q107238","display_name":"Eosinophil","level":3,"score":0.8813254833221436},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6879696846008301},{"id":"https://openalex.org/C2780638806","wikidata":"https://www.wikidata.org/wiki/Q495146","display_name":"Trichinosis","level":3,"score":0.6698043346405029},{"id":"https://openalex.org/C2777581317","wikidata":"https://www.wikidata.org/wiki/Q630285","display_name":"Trichinella","level":3,"score":0.6281889081001282},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6061424016952515},{"id":"https://openalex.org/C2779726973","wikidata":"https://www.wikidata.org/wiki/Q578994","display_name":"Helminthiasis","level":2,"score":0.4732908606529236},{"id":"https://openalex.org/C3017910909","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Peripheral blood","level":2,"score":0.4573286771774292},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.4453392028808594},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4220760762691498},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.40018177032470703},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19242551922798157},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001202","descriptor_name":"Ascitic Fluid","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004802","descriptor_name":"Eosinophilia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004804","descriptor_name":"Eosinophils","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014235","descriptor_name":"Trichinellosis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014235","descriptor_name":"Trichinellosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017160","descriptor_name":"Trichinella spiralis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-3024.1992.tb00024.x","doi":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3024.1992.tb00024.x","pdf_url":null,"source":{"id":"https://openalex.org/S80886111","display_name":"Parasite Immunology","issn_l":"0141-9838","issn":["0141-9838","1365-3024"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasite Immunology","raw_type":"journal-article"},{"id":"pmid:1437239","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1437239","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parasite immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W151682496","https://openalex.org/W1494116981","https://openalex.org/W1561665048","https://openalex.org/W1974823087","https://openalex.org/W2011658825","https://openalex.org/W2012351354","https://openalex.org/W2013396311","https://openalex.org/W2028670863","https://openalex.org/W2033553738","https://openalex.org/W2040323612","https://openalex.org/W2069532627","https://openalex.org/W2070315710","https://openalex.org/W2093087623","https://openalex.org/W2099865106","https://openalex.org/W2165894071","https://openalex.org/W2188384027","https://openalex.org/W2407376086"],"related_works":["https://openalex.org/W2090045566","https://openalex.org/W1779466565","https://openalex.org/W2013509806","https://openalex.org/W2065130624","https://openalex.org/W2014401306","https://openalex.org/W2410084691","https://openalex.org/W7073970868","https://openalex.org/W2003201398","https://openalex.org/W2086928223","https://openalex.org/W2254527574"],"abstract_inverted_index":{"Hypodense":[0,33],"eosinophils":[1,34,58],"are":[2],"observed":[3,36],"in":[4,22,27,37,41,79,84],"peripheral":[5,39],"blood":[6,40],"and":[7,97],"tissue":[8,53,69],"from":[9],"patients":[10],"with":[11,43,91],"eosinophilia":[12,70],"due":[13],"to":[14],"helminthic":[15],"infections.":[16],"In":[17,46],"this":[18],"study,":[19],"the":[20,38,63,66,72,80,85],"variation":[21],"eosinophil":[23],"density":[24],"was":[25,50,75],"examined":[26],"rats":[28],"during":[29],"Trichinella":[30,44],"spiralis":[31],"infection.":[32,45,64],"were":[35,59],"association":[42],"peritoneal":[47],"fluid,":[48,54],"which":[49],"representative":[51],"of":[52,57,62,68,87],"a":[55,76],"majority":[56],"hypodense":[60,88],"regardless":[61],"During":[65],"course":[67],"after":[71],"infection,":[73],"there":[74],"particular":[77],"increase":[78],"lowest":[81],"dense":[82],"cells":[83],"population":[86],"eosinophils.":[89],"Eosinophils":[90],"lower":[92],"density,":[93],"demonstrated":[94],"larger":[95],"diameters":[96],"had":[98],"more":[99],"potent":[100],"cytotoxic":[101],"activity.":[102]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}