{"id":"https://openalex.org/W2003551968","doi":"https://doi.org/10.1016/s0016-5085(96)70059-8","title":"Somatostatin receptor subtype 2 mediates inhibition of gastrin and histamine secretion from human, dog, and rat antrum","display_name":"Somatostatin receptor subtype 2 mediates inhibition of gastrin and histamine secretion from human, dog, and rat antrum","publication_year":1996,"publication_date":"1996-10-01","ids":{"openalex":"https://openalex.org/W2003551968","doi":"https://doi.org/10.1016/s0016-5085(96)70059-8","mag":"2003551968","pmid":"https://pubmed.ncbi.nlm.nih.gov/8831586"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(96)70059-8","doi":"https://doi.org/10.1016/s0016-5085(96)70059-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","pdf_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"M Zaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Zaki","raw_affiliation_strings":["Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081904339","display_name":"Leslie Harrington","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801770128","display_name":"Hunter Holmes McGuire VA Medical Center","ror":"https://ror.org/04fp78s33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801770128","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L Harrington","raw_affiliation_strings":["Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","institution_ids":["https://openalex.org/I2801770128","https://openalex.org/I72019824"]},{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004448875","display_name":"Robert W. McCuen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801770128","display_name":"Hunter Holmes McGuire VA Medical Center","ror":"https://ror.org/04fp78s33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801770128","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R McCuen","raw_affiliation_strings":["Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","institution_ids":["https://openalex.org/I2801770128","https://openalex.org/I72019824"]},{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110082148","display_name":"DH Coy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I2800269015","display_name":"Tulane Medical Center","ror":"https://ror.org/031w3f751","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800269015"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"DH Coy","raw_affiliation_strings":["Department of Medicine , Tulane University Medical Center , New Orleans , Louisiana ;","Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Tulane University Medical Center , New Orleans , Louisiana ;","institution_ids":["https://openalex.org/I114832834","https://openalex.org/I2800269015"]},{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078024136","display_name":"Akira Arimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Arimura","raw_affiliation_strings":["Department of Medicine , Tulane University , Belle Chase , Louisiana","Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Tulane University , Belle Chase , Louisiana","institution_ids":["https://openalex.org/I114832834"]},{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109309904","display_name":"M. L. Schubert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801770128","display_name":"Hunter Holmes McGuire VA Medical Center","ror":"https://ror.org/04fp78s33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801770128","https://openalex.org/I4210159720"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ML Schubert","raw_affiliation_strings":["Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","Department of Medicine, Medical College of Virginia, Richmond, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine , Medical College of Virginia and McGuire Veterans Affairs Medical Center , Richmond , Virginia ;","institution_ids":["https://openalex.org/I2801770128","https://openalex.org/I72019824"]},{"raw_affiliation_string":"Department of Medicine, Medical College of Virginia, Richmond, USA","institution_ids":["https://openalex.org/I72019824"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":1.5011,"has_fulltext":true,"cited_by_count":58,"citation_normalized_percentile":{"value":0.81855993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"111","issue":"4","first_page":"919","last_page":"924"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9359999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.9359999895095825,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.01140000019222498,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/somatostatin-receptor-2","display_name":"somatostatin receptor 2","score":0.9470000267028809},{"id":"https://openalex.org/keywords/somatostatin","display_name":"somatostatin","score":0.7490000128746033},{"id":"https://openalex.org/keywords/gastrin-secretion","display_name":"gastrin secretion","score":0.9860000014305115},{"id":"https://openalex.org/keywords/histamine-release","display_name":"histamine release","score":1.0},{"id":"https://openalex.org/keywords/gastric-antrum","display_name":"gastric antrum","score":0.9919999837875366},{"id":"https://openalex.org/keywords/somatostatin-analogs","display_name":"somatostatin analogues","score":0.8169999718666077},{"id":"https://openalex.org/keywords/species-comparison","display_name":"species comparison","score":0.49300000071525574}],"concepts":[{"id":"https://openalex.org/C2776297358","wikidata":"https://www.wikidata.org/wiki/Q407166","display_name":"Somatostatin","level":2,"score":0.8468637466430664},{"id":"https://openalex.org/C2776986829","wikidata":"https://www.wikidata.org/wiki/Q407181","display_name":"Gastrin","level":3,"score":0.8036988377571106},{"id":"https://openalex.org/C1122143","wikidata":"https://www.wikidata.org/wiki/Q61233","display_name":"Histamine","level":2,"score":0.7890950441360474},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7879956960678101},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.75824373960495},{"id":"https://openalex.org/C119811328","wikidata":"https://www.wikidata.org/wiki/Q2987004","display_name":"G cell","level":4,"score":0.6649275422096252},{"id":"https://openalex.org/C131253125","wikidata":"https://www.wikidata.org/wiki/Q609361","display_name":"Antrum","level":3,"score":0.6574435234069824},{"id":"https://openalex.org/C80115893","wikidata":"https://www.wikidata.org/wiki/Q2067077","display_name":"Somatostatin receptor","level":3,"score":0.5580812096595764},{"id":"https://openalex.org/C30862142","wikidata":"https://www.wikidata.org/wiki/Q288382","display_name":"Histamine H4 receptor","level":5,"score":0.5384194254875183},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.4878854751586914},{"id":"https://openalex.org/C55924715","wikidata":"https://www.wikidata.org/wiki/Q7309668","display_name":"Regulation of gastric function","level":4,"score":0.43872225284576416},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3768981397151947},{"id":"https://openalex.org/C34400551","wikidata":"https://www.wikidata.org/wiki/Q311568","display_name":"Histamine H2 receptor","level":4,"score":0.37058746814727783},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3587917685508728},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.34879350662231445},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.33762675523757935},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.26068711280822754},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2142222821712494},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.17746523022651672}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005755","descriptor_name":"Gastrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006636","descriptor_name":"Histamine Release","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011706","descriptor_name":"Pyloric Antrum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013004","descriptor_name":"Somatostatin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017481","descriptor_name":"Receptors, Somatostatin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0016-5085(96)70059-8","doi":"https://doi.org/10.1016/s0016-5085(96)70059-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","pdf_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},{"id":"pmid:8831586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8831586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(96)70059-8","doi":"https://doi.org/10.1016/s0016-5085(96)70059-8","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","pdf_url":"https://doi.org/10.1016/s0016-5085(96)70059-8","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2003551968.pdf","grobid_xml":"https://content.openalex.org/works/W2003551968.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W1963498145","https://openalex.org/W1992284590","https://openalex.org/W2046207475","https://openalex.org/W2066524003"],"related_works":["https://openalex.org/W4238321653","https://openalex.org/W2046207475","https://openalex.org/W2067838781","https://openalex.org/W2055934122","https://openalex.org/W1921949422","https://openalex.org/W1867187827","https://openalex.org/W2104587427","https://openalex.org/W1965939929","https://openalex.org/W2148340626","https://openalex.org/W2062599039"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}