{"id":"https://openalex.org/W2003449292","doi":"https://doi.org/10.1161/01.atv.0000258809.47285.07","title":"Deficiency of Glutathione Peroxidase-1 Accelerates the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice","display_name":"Deficiency of Glutathione Peroxidase-1 Accelerates the Progression of Atherosclerosis in Apolipoprotein E-Deficient Mice","publication_year":2007,"publication_date":"2007-01-26","ids":{"openalex":"https://openalex.org/W2003449292","doi":"https://doi.org/10.1161/01.atv.0000258809.47285.07","mag":"2003449292","pmid":"https://pubmed.ncbi.nlm.nih.gov/17255533"},"language":"en","primary_location":{"id":"doi:10.1161/01.atv.0000258809.47285.07","doi":"https://doi.org/10.1161/01.atv.0000258809.47285.07","is_oa":false,"landing_page_url":"https://doi.org/10.1161/01.atv.0000258809.47285.07","pdf_url":null,"source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030814855","display_name":"Michael Torzewski","orcid":"https://orcid.org/0000-0002-2756-2201","observed_orcids":["https://orcid.org/0000-0002-2756-2201"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Michael Torzewski","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019700293","display_name":"Viola Ochsenhirt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Viola Ochsenhirt","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111616121","display_name":"Andrei L. Kleschyov","orcid":"https://orcid.org/0000-0003-2300-1236","observed_orcids":["https://orcid.org/0000-0003-2300-1236"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Andrei L. Kleschyov","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064993444","display_name":"Matthias Walter Oelze","orcid":"https://orcid.org/0000-0002-5939-7263","observed_orcids":["https://orcid.org/0000-0002-5939-7263"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Matthias Oelze","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039361810","display_name":"Andreas Daiber","orcid":"https://orcid.org/0000-0002-2769-0094","observed_orcids":["https://orcid.org/0000-0002-2769-0094"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Andreas Daiber","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064206049","display_name":"Huige Li","orcid":"https://orcid.org/0000-0003-3458-7391","observed_orcids":["https://orcid.org/0000-0003-3458-7391"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Huige Li","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075123905","display_name":"Heidi Rossmann","orcid":"https://orcid.org/0000-0002-7532-8540","observed_orcids":["https://orcid.org/0000-0002-7532-8540"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Heidi Rossmann","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091030211","display_name":"Sotirios Tsimikas","orcid":"https://orcid.org/0000-0001-9834-9494","observed_orcids":["https://orcid.org/0000-0001-9834-9494"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Sotirios Tsimikas","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072726806","display_name":"Kurt Reifenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Kurt Reifenberg","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036614640","display_name":"Fei Cheng","orcid":"https://orcid.org/0000-0002-3309-0618","observed_orcids":["https://orcid.org/0000-0002-3309-0618","https://orcid.org/0009-0000-1201-5056"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Fei Cheng","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002090343","display_name":"Hans\u2010Anton Lehr","orcid":"https://orcid.org/0000-0001-8078-1035","observed_orcids":["https://orcid.org/0000-0001-8078-1035"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Hans-Anton Lehr","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030454575","display_name":"Stefan Blankenberg","orcid":"https://orcid.org/0000-0001-6488-2362","observed_orcids":["https://orcid.org/0000-0001-6488-2362"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Stefan Blankenberg","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111534684","display_name":"Ulrich F\u00f6rstermann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Ulrich Fo\u0308rstermann","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113521673","display_name":"Thomas F. M\u00fcnzel","orcid":"https://orcid.org/0000-0001-5503-4150","observed_orcids":["https://orcid.org/0000-0001-5503-4150"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Thomas Mu\u0308nzel","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075174977","display_name":"Karl Johannes Lackner","orcid":"https://orcid.org/0000-0002-1985-7931","observed_orcids":["https://orcid.org/0000-0002-1985-7931"]},"institutions":[{"id":"https://openalex.org/I197323543","display_name":"Johannes Gutenberg University Mainz","ror":"https://ror.org/023b0x485","country_code":"DE","type":"education","lineage":["https://openalex.org/I197323543"]},{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210094062","display_name":"University Medical Center of the Johannes Gutenberg University Mainz","ror":"https://ror.org/00q1fsf04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210094062"]}],"countries":["CH","DE","US"],"is_corresponding":false,"raw_author_name":"Karl J. Lackner","raw_affiliation_strings":["From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","Division of Cardiology (S.T), University of California, San Diego, Calif","Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institute of Clinical Chemistry and Laboratory Medicine (M.T., V.O., F.C., H.R., K.J.L.), Department of Medicine II (A.L.K., M.O., A.D., S.B., T.M.), Department of Pharmacology (H.L., U.F.), Central Laboratory Animal Facility (K.R.), Johannes Gutenberg University, Mainz, Germany; Division of Cardiology (S.T), University of California, San Diego, Calif; Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I197323543","https://openalex.org/I36258959","https://openalex.org/I4210094062"]},{"raw_affiliation_string":"Division of Cardiology (S.T), University of California, San Diego, Calif","institution_ids":["https://openalex.org/I36258959"]},{"raw_affiliation_string":"Institute Universitaire de Pathologie (H-A.L.), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6109,"has_fulltext":true,"cited_by_count":186,"citation_normalized_percentile":{"value":0.93809289,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"27","issue":"4","first_page":"850","last_page":"857"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.6894999742507935,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases","score":0.6894999742507935,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.14010000228881836,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.06589999794960022,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutathione-peroxidase-1","display_name":"glutathione peroxidase 1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/apolipoprotein-e-deficiency","display_name":"apolipoprotein E deficiency","score":0.9129999876022339},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.765999972820282},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9610000252723694},{"id":"https://openalex.org/keywords/peroxynitrite","display_name":"peroxynitrite","score":0.9610000252723694},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.8410000205039978},{"id":"https://openalex.org/keywords/tyrosine-nitration","display_name":"tyrosine nitration","score":0.9380000233650208},{"id":"https://openalex.org/keywords/macrophage-proliferation","display_name":"macrophage proliferation","score":0.8989999890327454},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.5429999828338623},{"id":"https://openalex.org/keywords/western-diet","display_name":"Western diet","score":0.7419999837875366},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2778760513","wikidata":"https://www.wikidata.org/wiki/Q24773045","display_name":"Glutathione peroxidase","level":4,"score":0.7562091946601868},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.696204662322998},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6951225996017456},{"id":"https://openalex.org/C57089818","wikidata":"https://www.wikidata.org/wiki/Q424728","display_name":"Apolipoprotein E","level":3,"score":0.6010853052139282},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5810279846191406},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.5118035674095154},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.4455114006996155},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.4127291738986969},{"id":"https://openalex.org/C182704531","wikidata":"https://www.wikidata.org/wiki/Q1364740","display_name":"Knockout mouse","level":3,"score":0.41128289699554443},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39711135625839233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3251921236515045},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26457488536834717},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20876100659370422},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.1947222650051117},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.12623143196105957},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.11196699738502502},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.054907768964767456},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000094765","descriptor_name":"Glutathione Peroxidase GPX1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001057","descriptor_name":"Apolipoproteins E","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005979","descriptor_name":"Glutathione Peroxidase","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008566","descriptor_name":"Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008929","descriptor_name":"Mitochondria, Heart","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013481","descriptor_name":"Superoxides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030421","descriptor_name":"Peroxynitrous Acid","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D050197","descriptor_name":"Atherosclerosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1161/01.atv.0000258809.47285.07","doi":"https://doi.org/10.1161/01.atv.0000258809.47285.07","is_oa":false,"landing_page_url":"https://doi.org/10.1161/01.atv.0000258809.47285.07","pdf_url":null,"source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},{"id":"pmid:17255533","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17255533","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, thrombosis, and vascular biology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unil.ch:iris/240010","doi":null,"is_oa":false,"landing_page_url":"https://iris.unil.ch/handle/iris/240010","pdf_url":null,"source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:serval.unil.ch:BIB_E0AE7A0E32AB","doi":null,"is_oa":false,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_E0AE7A0E32AB","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Arteriosclerosis Thrombosis and Vascular Biology, vol. 27, no. 4, pp. 850-857","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309272","display_name":"Wayne State University","ror":"https://ror.org/01070mq45"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W1122013619","https://openalex.org/W1591054099","https://openalex.org/W1650965741","https://openalex.org/W1678920698","https://openalex.org/W1969459077","https://openalex.org/W1976616659","https://openalex.org/W1977597523","https://openalex.org/W1978640785","https://openalex.org/W1981868559","https://openalex.org/W1984124570","https://openalex.org/W1984486105","https://openalex.org/W1991726504","https://openalex.org/W1993047629","https://openalex.org/W1999880393","https://openalex.org/W2006313098","https://openalex.org/W2011119922","https://openalex.org/W2019337039","https://openalex.org/W2020438152","https://openalex.org/W2030929060","https://openalex.org/W2035909384","https://openalex.org/W2050461130","https://openalex.org/W2051124233","https://openalex.org/W2056333208","https://openalex.org/W2058000497","https://openalex.org/W2066367755","https://openalex.org/W2070834812","https://openalex.org/W2073703119","https://openalex.org/W2081182178","https://openalex.org/W2090253601","https://openalex.org/W2097082675","https://openalex.org/W2097155911","https://openalex.org/W2098279350","https://openalex.org/W2098883620","https://openalex.org/W2101518804","https://openalex.org/W2104061846","https://openalex.org/W2104128564","https://openalex.org/W2104989112","https://openalex.org/W2105791880","https://openalex.org/W2108390397","https://openalex.org/W2109166221","https://openalex.org/W2115871167","https://openalex.org/W2120845918","https://openalex.org/W2133031701","https://openalex.org/W2138189523","https://openalex.org/W2138239251","https://openalex.org/W2139527140","https://openalex.org/W2154098294","https://openalex.org/W2154500970","https://openalex.org/W2164792647","https://openalex.org/W2165421304","https://openalex.org/W2168595038","https://openalex.org/W2170450373","https://openalex.org/W2172249877","https://openalex.org/W2236001816","https://openalex.org/W2291692906"],"related_works":["https://openalex.org/W2026981610","https://openalex.org/W7100615330","https://openalex.org/W2104061846","https://openalex.org/W1974922478","https://openalex.org/W2050461130","https://openalex.org/W6889043317","https://openalex.org/W2015589441","https://openalex.org/W1981079353","https://openalex.org/W7211989210","https://openalex.org/W2022456632"],"abstract_inverted_index":{"BACKGROUND:":[0],"We":[1],"have":[2],"recently":[3],"demonstrated":[4],"that":[5,104],"activity":[6],"of":[7,19,34,146,159,164],"red":[8],"blood":[9],"cell":[10],"glutathione":[11,35,55,90,105],"peroxidase-1":[12,36,56,91,106],"is":[13],"inversely":[14],"associated":[15],"with":[16,24,52,98],"the":[17,32,41,116],"risk":[18],"cardiovascular":[20],"events":[21],"in":[22,40,115,133,136,174],"patients":[23],"coronary":[25],"artery":[26],"disease.":[27],"The":[28],"present":[29],"study":[30],"analyzed":[31],"effect":[33],"deficiency":[37,57,92,107],"on":[38,60,74],"atherogenesis":[39],"apolipoprotein":[42,49,86,175],"E-deficient":[43,50,87,176],"mouse.":[44],"METHODS":[45],"AND":[46],"RESULTS:":[47],"Female":[48],"mice":[51,78,130],"and":[53,169],"without":[54],"were":[58],"placed":[59],"a":[61,157],"Western-type":[62,75],"diet":[63],"for":[64],"another":[65],"6,":[66],"12,":[67],"or":[68],"24":[69,72],"weeks.":[70],"After":[71],"weeks":[73],"diet,":[76],"double-knockout":[77,129],"(GPx-1(-/-)ApoE(-/-))":[79],"developed":[80],"significantly":[81],"more":[82],"atherosclerosis":[83],"than":[84],"control":[85],"mice.":[88,177],"Moreover,":[89],"led":[93],"to":[94,109,138],"modified":[95],"atherosclerotic":[96,171],"lesions":[97],"increased":[99,110,122,132,153],"cellularity.":[100],"Functional":[101],"experiments":[102],"revealed":[103],"leads":[108],"reactive":[111],"oxygen":[112],"species":[113],"concentration":[114],"aortic":[117],"wall":[118],"as":[119,121,150,152,156],"well":[120,151],"overall":[123],"oxidative":[124],"stress.":[125],"Peritoneal":[126],"macrophages":[127],"from":[128],"showed":[131],"vitro":[134],"proliferation":[135],"response":[137],"macrophage-colony-stimulating":[139],"factor.":[140],"Also,":[141],"we":[142],"found":[143],"lower":[144],"levels":[145],"bioactive":[147],"nitric":[148],"oxide":[149],"tyrosine":[154],"nitration":[155],"marker":[158],"peroxynitrite":[160],"production.":[161],"CONCLUSIONS:":[162],"Deficiency":[163],"an":[165],"antioxidative":[166],"enzyme":[167],"accelerates":[168],"modifies":[170],"lesion":[172],"progression":[173]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":20},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":12}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}