{"id":"https://openalex.org/W2003442364","doi":"https://doi.org/10.1002/bies.950150602","title":"Genetic control of fungal differentiation: The three sporulation pathways of Neurospora crassa","display_name":"Genetic control of fungal differentiation: The three sporulation pathways of Neurospora crassa","publication_year":1993,"publication_date":"1993-06-01","ids":{"openalex":"https://openalex.org/W2003442364","doi":"https://doi.org/10.1002/bies.950150602","mag":"2003442364","pmid":"https://pubmed.ncbi.nlm.nih.gov/8357339"},"language":"en","primary_location":{"id":"doi:10.1002/bies.950150602","doi":"https://doi.org/10.1002/bies.950150602","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bies.950150602","pdf_url":null,"source":{"id":"https://openalex.org/S27819959","display_name":"BioEssays","issn_l":"0265-9247","issn":["0265-9247","1521-1878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioEssays","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2003442364"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086579894","display_name":"Matthew L. Springer","orcid":"https://orcid.org/0000-0002-6689-8234","observed_orcids":["https://orcid.org/0000-0002-6689-8234"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matthew L. Springer","raw_affiliation_strings":["Department of Biochemistry, Stanford University School of Medicine, CA 94305","Departments of Biochemistry and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Stanford University School of Medicine, CA 94305","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"raw_affiliation_string":"Departments of Biochemistry and Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5086579894"],"corresponding_institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"],"apc_list":{"value":5330,"currency":"USD","value_usd":5330},"apc_paid":null,"fwci":0.2839,"has_fulltext":false,"cited_by_count":168,"citation_normalized_percentile":{"value":0.32887701,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"15","issue":"6","first_page":"365","last_page":"374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurospora-crassa","display_name":"Neurospora crassa","score":0.984000027179718},{"id":"https://openalex.org/keywords/fungal-sporulation","display_name":"fungal sporulation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/asexual-sporulation","display_name":"asexual sporulation","score":0.7950000166893005},{"id":"https://openalex.org/keywords/macroconidia","display_name":"macroconidia","score":0.8730000257492065},{"id":"https://openalex.org/keywords/microconidia","display_name":"microconidia","score":1.0},{"id":"https://openalex.org/keywords/perithecia","display_name":"perithecia","score":0.9639999866485596},{"id":"https://openalex.org/keywords/asci","display_name":"asci","score":0.7559999823570251},{"id":"https://openalex.org/keywords/ascospores","display_name":"ascospores","score":0.9369999766349792},{"id":"https://openalex.org/keywords/meiosis","display_name":"meiosis","score":0.8560000061988831},{"id":"https://openalex.org/keywords/developmental-gene-regulation","display_name":"developmental gene regulation","score":0.5640000104904175},{"id":"https://openalex.org/keywords/developmental-mutants","display_name":"developmental mutants","score":0.48100000619888306},{"id":"https://openalex.org/keywords/fungal-development","display_name":"fungal development","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C2776739539","wikidata":"https://www.wikidata.org/wiki/Q133459","display_name":"Neurospora crassa","level":4,"score":0.966577410697937},{"id":"https://openalex.org/C2776769606","wikidata":"https://www.wikidata.org/wiki/Q309943","display_name":"Neurospora","level":5,"score":0.8572244644165039},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8358207941055298},{"id":"https://openalex.org/C174618031","wikidata":"https://www.wikidata.org/wiki/Q177332","display_name":"Spore","level":2,"score":0.8301792144775391},{"id":"https://openalex.org/C2777251434","wikidata":"https://www.wikidata.org/wiki/Q5182483","display_name":"Crassa","level":5,"score":0.8103272318840027},{"id":"https://openalex.org/C198410946","wikidata":"https://www.wikidata.org/wiki/Q845312","display_name":"Budding","level":2,"score":0.7412798404693604},{"id":"https://openalex.org/C90080823","wikidata":"https://www.wikidata.org/wiki/Q193129","display_name":"Hypha","level":2,"score":0.70660400390625},{"id":"https://openalex.org/C43143990","wikidata":"https://www.wikidata.org/wiki/Q612960","display_name":"Conidium","level":2,"score":0.6867690086364746},{"id":"https://openalex.org/C115505304","wikidata":"https://www.wikidata.org/wiki/Q2085099","display_name":"Sporogenesis","level":3,"score":0.6557161211967468},{"id":"https://openalex.org/C2779347548","wikidata":"https://www.wikidata.org/wiki/Q5161043","display_name":"Conidiation","level":4,"score":0.573970377445221},{"id":"https://openalex.org/C148196450","wikidata":"https://www.wikidata.org/wiki/Q21100485","display_name":"Meiosis","level":3,"score":0.5284243226051331},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5041636228561401},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47027164697647095},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.45190492272377014},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4311956465244293},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3066815733909607},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.24180451035499573}],"mesh":[{"descriptor_ui":"D005800","descriptor_name":"Genes, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009492","descriptor_name":"Neurospora crassa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009492","descriptor_name":"Neurospora crassa","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009492","descriptor_name":"Neurospora crassa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013172","descriptor_name":"Spores, Fungal","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013172","descriptor_name":"Spores, Fungal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/bies.950150602","doi":"https://doi.org/10.1002/bies.950150602","is_oa":false,"landing_page_url":"https://doi.org/10.1002/bies.950150602","pdf_url":null,"source":{"id":"https://openalex.org/S27819959","display_name":"BioEssays","issn_l":"0265-9247","issn":["0265-9247","1521-1878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioEssays","raw_type":"journal-article"},{"id":"pmid:8357339","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8357339","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioEssays : news and reviews in molecular, cellular and developmental biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W35173392","https://openalex.org/W1543462028","https://openalex.org/W1551348579","https://openalex.org/W1764152111","https://openalex.org/W1768392717","https://openalex.org/W1768647805","https://openalex.org/W1782142368","https://openalex.org/W1837513873","https://openalex.org/W1897053563","https://openalex.org/W1906346542","https://openalex.org/W1915843950","https://openalex.org/W1916151155","https://openalex.org/W1916193949","https://openalex.org/W1935781249","https://openalex.org/W1945809520","https://openalex.org/W1986657721","https://openalex.org/W1988116260","https://openalex.org/W1989485245","https://openalex.org/W1990283021","https://openalex.org/W1993082622","https://openalex.org/W1998871484","https://openalex.org/W2007378469","https://openalex.org/W2011602921","https://openalex.org/W2018967072","https://openalex.org/W2021624494","https://openalex.org/W2025443352","https://openalex.org/W2025997852","https://openalex.org/W2026230298","https://openalex.org/W2030825540","https://openalex.org/W2031401665","https://openalex.org/W2043148416","https://openalex.org/W2049753026","https://openalex.org/W2052501207","https://openalex.org/W2052639804","https://openalex.org/W2052670332","https://openalex.org/W2054559471","https://openalex.org/W2055747989","https://openalex.org/W2059160267","https://openalex.org/W2065026560","https://openalex.org/W2072442277","https://openalex.org/W2073328740","https://openalex.org/W2076705145","https://openalex.org/W2079430652","https://openalex.org/W2101399690","https://openalex.org/W2109312212","https://openalex.org/W2135385723","https://openalex.org/W2147354554","https://openalex.org/W2155905797","https://openalex.org/W2165436181","https://openalex.org/W2166882700","https://openalex.org/W2170626534","https://openalex.org/W2170712248","https://openalex.org/W2317475090","https://openalex.org/W2323693895","https://openalex.org/W2591868306","https://openalex.org/W2591978139","https://openalex.org/W2593821001","https://openalex.org/W2594917796","https://openalex.org/W2800398444"],"related_works":["https://openalex.org/W2135385723","https://openalex.org/W4302031658","https://openalex.org/W1997801720","https://openalex.org/W2042410606","https://openalex.org/W2076705145","https://openalex.org/W2072442277","https://openalex.org/W107402477","https://openalex.org/W2540536643","https://openalex.org/W1533504433","https://openalex.org/W1512676329"],"abstract_inverted_index":{"Sporulation":[0],"in":[1,60,69,119],"the":[2,15,29,51],"mold":[3],"Neurospora":[4,94],"crassa":[5],"can":[6],"proceed":[7],"along":[8],"three":[9,18],"very":[10],"different":[11,41],"pathways,":[12],"leading":[13],"to":[14,28,103],"production":[16],"of":[17,20,31,53,108],"types":[19],"spores.":[21],"Two":[22],"asexual":[23],"sporulation":[24,95],"pathways":[25,81,96],"that":[26,77,87,110],"lead":[27],"formation":[30,52],"macroconidia":[32],"and":[33,65,82,106,121],"microconidia":[34],"involve":[35],"budding":[36],"from":[37],"hyphae":[38],"by":[39,114],"two":[40],"mechanisms.":[42],"A":[43],"much":[44],"more":[45],"complex":[46,115],"sexual":[47],"reproductive":[48],"pathway":[49],"involves":[50],"a":[54,58,98],"fruiting":[55],"body":[56],"called":[57,72],"perithecium,":[59],"which":[61,102],"meiosis":[62],"takes":[63],"place":[64],"ascospores":[66],"are":[67,88,111],"formed":[68],"sac-like":[70],"cells":[71],"asci.":[73],"Numerous":[74],"mutations":[75],"exist":[76],"affect":[78],"these":[79],"developmental":[80],"genes":[83],"have":[84],"been":[85],"isolated":[86],"expressed":[89],"preferentially":[90],"during":[91],"sporulation.":[92],"The":[93],"offer":[97],"simple":[99],"system":[100],"with":[101],"study":[104],"mechanisms":[105],"regulation":[107],"development":[109],"usually":[112],"obscured":[113],"cell-cell":[116],"interactions":[117],"involved":[118],"animal":[120],"plant":[122],"development.":[123]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2016-06-24T00:00:00"}
