{"id":"https://openalex.org/W2003288709","doi":"https://doi.org/10.1016/j.bmcl.2007.07.056","title":"Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3\u03b2","display_name":"Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3\u03b2","publication_year":2007,"publication_date":"2007-08-20","ids":{"openalex":"https://openalex.org/W2003288709","doi":"https://doi.org/10.1016/j.bmcl.2007.07.056","mag":"2003288709","pmid":"https://pubmed.ncbi.nlm.nih.gov/17764934"},"language":"en","primary_location":{"id":"doi:10.1016/j.bmcl.2007.07.056","doi":"https://doi.org/10.1016/j.bmcl.2007.07.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2007.07.056","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108382767","display_name":"Dongkyu Shin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]},{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dongkyu Shin","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","Department of Chemistry and School of Molecular Science (BK 21), KAIST, Daejeon 305-701, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]},{"raw_affiliation_string":"Department of Chemistry and School of Molecular Science (BK 21), KAIST, Daejeon 305-701, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100626897","display_name":"Seung\u2010Chul Lee","orcid":"https://orcid.org/0000-0002-1034-1410","observed_orcids":["https://orcid.org/0000-0002-1034-1410"]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seung-Chul Lee","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040508274","display_name":"Yong\u2010Seok Heo","orcid":"https://orcid.org/0000-0003-3080-4109","observed_orcids":["https://orcid.org/0000-0003-3080-4109"]},"institutions":[{"id":"https://openalex.org/I24062138","display_name":"Konkuk University","ror":"https://ror.org/025h1m602","country_code":"KR","type":"education","lineage":["https://openalex.org/I24062138"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yong-Seok Heo","raw_affiliation_strings":["Department of Chemistry, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea","institution_ids":["https://openalex.org/I24062138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059562926","display_name":"Woon\u2010Young Lee","orcid":"https://orcid.org/0000-0002-4345-5385","observed_orcids":["https://orcid.org/0000-0002-4345-5385"]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Woon-Young Lee","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026101027","display_name":"Yong\u2010Soon Cho","orcid":"https://orcid.org/0000-0003-1424-1123","observed_orcids":["https://orcid.org/0000-0003-1424-1123"]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yong-Soon Cho","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110946102","display_name":"Yong Eun Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yong Eun Kim","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024344659","display_name":"Young\u2010Lan Hyun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young-Lan Hyun","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109081669","display_name":"Joong Myung Cho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Joong Myung Cho","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113216231","display_name":"Yoon Sup Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yoon Sup Lee","raw_affiliation_strings":["Department of Chemistry and School of Molecular Science (BK 21), KAIST, Daejeon 305-701, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and School of Molecular Science (BK 21), KAIST, Daejeon 305-701, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112192491","display_name":"Seonggu Ro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165981","display_name":"CrystalGenomics (South Korea)","ror":"https://ror.org/05gk7hr65","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210165981"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Seonggu Ro","raw_affiliation_strings":["CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CrystalGenomics, Inc., Asan Institute for Life Sciences, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, Republic of Korea","institution_ids":["https://openalex.org/I4210165981"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5112192491"],"corresponding_institution_ids":["https://openalex.org/I4210165981"],"apc_list":{"value":3880,"currency":"USD","value_usd":3880},"apc_paid":null,"fwci":1.5339,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.79019095,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"17","issue":"20","first_page":"5686","last_page":"5689"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.260699987411499,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.03790000081062317,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glycogen-synthase-kinase-3beta","display_name":"glycogen synthase kinase-3\u03b2","score":0.8809999823570251},{"id":"https://openalex.org/keywords/atp-competitive-inhibitors","display_name":"ATP-competitive inhibitors","score":0.9440000057220459},{"id":"https://openalex.org/keywords/protein-kinase-inhibitors","display_name":"protein kinase inhibitors","score":0.8019999861717224},{"id":"https://openalex.org/keywords/hinge-region","display_name":"hinge region","score":0.6179999709129333},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.7360000014305115},{"id":"https://openalex.org/keywords/first-principles-calculations","display_name":"first-principles calculations","score":0.9010000228881836},{"id":"https://openalex.org/keywords/x-ray-crystal-structure","display_name":"X-ray crystal structure","score":0.6620000004768372},{"id":"https://openalex.org/keywords/kinase-inhibitor-design","display_name":"kinase inhibitor design","score":0.492000013589859}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9080504179000854},{"id":"https://openalex.org/C182996813","wikidata":"https://www.wikidata.org/wiki/Q910847","display_name":"GSK-3","level":3,"score":0.7214080691337585},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.6369690299034119},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5982083678245544},{"id":"https://openalex.org/C192118531","wikidata":"https://www.wikidata.org/wiki/Q86360001","display_name":"Glycogen synthase","level":3,"score":0.5963714122772217},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5293462872505188},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.5160650610923767},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.43594256043434143},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.42335444688796997},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.41437941789627075},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.4107036590576172},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.37133321166038513},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.2247389554977417},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1155858039855957},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001554","descriptor_name":"Benzene","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007093","descriptor_name":"Imidazoles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D038362","descriptor_name":"Glycogen Synthase Kinase 3","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D038362","descriptor_name":"Glycogen Synthase Kinase 3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D047428","descriptor_name":"Protein Kinase Inhibitors","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D047428","descriptor_name":"Protein Kinase Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D047428","descriptor_name":"Protein Kinase Inhibitors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bmcl.2007.07.056","doi":"https://doi.org/10.1016/j.bmcl.2007.07.056","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2007.07.056","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},{"id":"pmid:17764934","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17764934","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & medicinal chemistry letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1833591189","https://openalex.org/W2019811153","https://openalex.org/W2031179697","https://openalex.org/W2051788298","https://openalex.org/W2059317968","https://openalex.org/W2098017074","https://openalex.org/W2114358785","https://openalex.org/W2170161564","https://openalex.org/W2170537843","https://openalex.org/W4293242696"],"related_works":["https://openalex.org/W2950179613","https://openalex.org/W1976241366","https://openalex.org/W2148165059","https://openalex.org/W2088351558","https://openalex.org/W2952409318","https://openalex.org/W2524453358","https://openalex.org/W2172755583","https://openalex.org/W2056810857","https://openalex.org/W2062224156","https://openalex.org/W2083259904"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}