{"id":"https://openalex.org/W2003278596","doi":"https://doi.org/10.1098/rspb.1972.0015","title":"Metabolic pathways of steroids in insects","display_name":"Metabolic pathways of steroids in insects","publication_year":1972,"publication_date":"1972-02-15","ids":{"openalex":"https://openalex.org/W2003278596","doi":"https://doi.org/10.1098/rspb.1972.0015","mag":"2003278596","pmid":"https://pubmed.ncbi.nlm.nih.gov/4401777"},"language":"en","primary_location":{"id":"doi:10.1098/rspb.1972.0015","doi":"https://doi.org/10.1098/rspb.1972.0015","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rspb.1972.0015","pdf_url":null,"source":{"id":"https://openalex.org/S3006207977","display_name":"Proceedings of the Royal Society B Biological Sciences","issn_l":"0080-4649","issn":["0080-4649","0962-8452","1471-2954","2053-9193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Royal Society of London. Series B. Biological Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043260178","display_name":"M. J. Thompson","orcid":"https://orcid.org/0000-0002-0279-5340","observed_orcids":["https://orcid.org/0000-0002-0279-5340"]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. J. Thompson","raw_affiliation_strings":["Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043672019","display_name":"James A. Svoboda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. A. Svoboda","raw_affiliation_strings":["Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052645391","display_name":"John N. Kaplanis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. N. Kaplanis","raw_affiliation_strings":["Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007171882","display_name":"William E. Robbins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1312222531","display_name":"Agricultural Research Service","ror":"https://ror.org/02d2m2044","country_code":"US","type":"government","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I1336096307","display_name":"United States Department of Agriculture","ror":"https://ror.org/01na82s61","country_code":"US","type":"government","lineage":["https://openalex.org/I1336096307"]},{"id":"https://openalex.org/I4210125976","display_name":"Beltsville Agricultural Research Center","ror":"https://ror.org/03b08sh51","country_code":"US","type":"facility","lineage":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976","https://openalex.org/I4210138094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. E. Robbins","raw_affiliation_strings":["Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Insect Physiology Laboratory, Entomology Research Division, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland 20705","institution_ids":["https://openalex.org/I1312222531","https://openalex.org/I1336096307","https://openalex.org/I4210125976"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":14.0938,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.99782192,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"180","issue":"1059","first_page":"203","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13736","display_name":"Steroid Chemistry and Biochemistry","score":0.8798999786376953,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13736","display_name":"Steroid Chemistry and Biochemistry","score":0.8798999786376953,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.061000000685453415,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.024800000712275505,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sterol-metabolism","display_name":"sterol metabolism","score":0.8740000128746033},{"id":"https://openalex.org/keywords/phytosterols","display_name":"phytosterols","score":0.8149999976158142},{"id":"https://openalex.org/keywords/cholesterol-synthesis","display_name":"cholesterol biosynthesis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/ecdysteroids","display_name":"ecdysteroids","score":0.800000011920929},{"id":"https://openalex.org/keywords/ecdysone","display_name":"ecdysone","score":0.8830000162124634},{"id":"https://openalex.org/keywords/ecdysteroid-biosynthesis","display_name":"ecdysteroid biosynthesis","score":0.847000002861023},{"id":"https://openalex.org/keywords/sterol-precursors","display_name":"sterol precursors","score":0.7990000247955322},{"id":"https://openalex.org/keywords/insect-physiology","display_name":"insect physiology","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C2778718757","wikidata":"https://www.wikidata.org/wiki/Q143623","display_name":"Sterol","level":3,"score":0.851616621017456},{"id":"https://openalex.org/C41905685","wikidata":"https://www.wikidata.org/wiki/Q381084","display_name":"Moulting","level":3,"score":0.7259626984596252},{"id":"https://openalex.org/C2776905768","wikidata":"https://www.wikidata.org/wiki/Q138983","display_name":"Ecdysteroid","level":3,"score":0.7131351232528687},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.6586925983428955},{"id":"https://openalex.org/C192989942","wikidata":"https://www.wikidata.org/wiki/Q68685","display_name":"Metabolic pathway","level":3,"score":0.6478410959243774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6337673664093018},{"id":"https://openalex.org/C2779718769","wikidata":"https://www.wikidata.org/wiki/Q412457","display_name":"Phytosterol","level":2,"score":0.5725314021110535},{"id":"https://openalex.org/C2780902042","wikidata":"https://www.wikidata.org/wiki/Q177911","display_name":"Steroid","level":3,"score":0.5305647850036621},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5077296495437622},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.45607784390449524},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.4377075433731079},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41762053966522217},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1950429379940033},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.15331825613975525},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.07593837380409241}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001517","descriptor_name":"Coleoptera","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D003058","descriptor_name":"Cockroaches","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003640","descriptor_name":"Dealkylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004440","descriptor_name":"Ecdysone","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D006793","descriptor_name":"Houseflies","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012831","descriptor_name":"Bombyx","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013256","descriptor_name":"Steroids","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D013261","descriptor_name":"Sterols","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1098/rspb.1972.0015","doi":"https://doi.org/10.1098/rspb.1972.0015","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rspb.1972.0015","pdf_url":null,"source":{"id":"https://openalex.org/S3006207977","display_name":"Proceedings of the Royal Society B Biological Sciences","issn_l":"0080-4649","issn":["0080-4649","0962-8452","1471-2954","2053-9193"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Royal Society of London. Series B. Biological Sciences","raw_type":"journal-article"},{"id":"pmid:4401777","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4401777","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the Royal Society of London. Series B, Biological sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W560571822","https://openalex.org/W2084236846"],"related_works":["https://openalex.org/W1974428658","https://openalex.org/W2345917687","https://openalex.org/W136647394","https://openalex.org/W2022581093","https://openalex.org/W4247588603","https://openalex.org/W2493191212","https://openalex.org/W7124716625","https://openalex.org/W4248137605","https://openalex.org/W2001967072","https://openalex.org/W2798570064"],"abstract_inverted_index":{"Abstract":[0],"This":[1],"paper":[2],"discusses":[3],"sterol":[4,60,86],"metabolism":[5,61,68],"and":[6,29,55,67,97,107,128],"utilization":[7],"in":[8,22,43,62,94,103,114,126],"insects":[9,75,115],"with":[10],"particular":[11],"emphasis":[12],"on":[13],"the":[14,40,44,56,70,78,85,89,91,98,101],"two":[15],"known":[16],"major":[17],"metabolic":[18,112],"pathways":[19,113,125],"for":[20],"steroids":[21],"insects:":[23],"(1)":[24],"The":[25,65,105],"conversion":[26,45],"of":[27,39,46,52,59,69,74,81,84,88,100,110],"C28":[28],"C29":[30],"plant":[31],"sterols":[32],"to":[33,48,123],"cholesterol,":[34,49],"including":[35,77],"a":[36],"comprehensive":[37],"survey":[38],"intermediates":[41,93],"involved":[42],"phytosterols":[47],"certain":[50],"inhibitors":[51],"phytosterol":[53],"metabolism,":[54],"end":[57],"products":[58],"insects.":[63,104],"(2)":[64],"biosynthesis":[66],"steroid":[71],"moulting":[72],"hormones":[73],"(ecdysones),":[76],"present":[79],"state":[80],"our":[82],"knowledge":[83],"precursors":[87],"ecdysones,":[90],"ecdysteroid":[92],"their":[95,121],"biosynthesis,":[96],"inactivation":[99],"ecdysteroids":[102],"biological":[106],"physiological":[108],"significance":[109],"these":[111],"is":[116],"discussed,":[117],"as":[118,120],"well":[119],"relationship":[122],"analogous":[124],"plants":[127],"vertebrates.":[129]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}