{"id":"https://openalex.org/W2003273154","doi":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","title":"ABO(H) antigens and beta-2 microglobulin in transitional cell carcinoma. Predictors of response to intravesical bacillus calmette-guerin","display_name":"ABO(H) antigens and beta-2 microglobulin in transitional cell carcinoma. Predictors of response to intravesical bacillus calmette-guerin","publication_year":1991,"publication_date":"1991-06-15","ids":{"openalex":"https://openalex.org/W2003273154","doi":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","mag":"2003273154","pmid":"https://pubmed.ncbi.nlm.nih.gov/1710534"},"language":"en","primary_location":{"id":"doi:10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","doi":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819910615%2967%3A12%3C3024%3A%3AAID-CNCR2820671216%3E3.0.CO%3B2-Q","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2003273154"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819910615%2967%3A12%3C3024%3A%3AAID-CNCR2820671216%3E3.0.CO%3B2-Q","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111547238","display_name":"Holt Sanders","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Holt Sanders","raw_affiliation_strings":["Department of Surgery (Urology), Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery (Urology), Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012659487","display_name":"Peter A. McCue","orcid":"https://orcid.org/0000-0001-9806-0594","observed_orcids":["https://orcid.org/0000-0001-9806-0594"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter McCue","raw_affiliation_strings":["Departments of Surgery (Urology) and Pathology, Emory University School of Medicine, Atlanta, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery (Urology) and Pathology, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110862536","display_name":"SAM D. JR GRAHAM","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]},{"id":"https://openalex.org/I4210096060","display_name":"Emory Clinic","ror":"https://ror.org/00tb5pg67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4210096060"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sam D. Graham","raw_affiliation_strings":["Departments of Surgery (Urology) and Pathology, Emory University School of Medicine, Atlanta, Georgia","Department of Surgery, Division of Urology, Emory Clinic, 1365 Clifton Road, N.E., Atlanta, GA 30322"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Surgery (Urology) and Pathology, Emory University School of Medicine, Atlanta, Georgia","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Surgery, Division of Urology, Emory Clinic, 1365 Clifton Road, N.E., Atlanta, GA 30322","institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210096060"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110862536"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I4210096060"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":null,"fwci":1.8963,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.83553225,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"67","issue":"12","first_page":"3024","last_page":"3028"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12695","display_name":"Urinary and Genital Oncology Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta2-microglobulin","display_name":"beta2-microglobulin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/superficial-bladder-cancer","display_name":"superficial bladder cancer","score":0.6859999895095825},{"id":"https://openalex.org/keywords/urothelial-carcinoma","display_name":"urothelial carcinoma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/intravesical-chemotherapy","display_name":"intravesical chemotherapy","score":0.8420000076293945},{"id":"https://openalex.org/keywords/bcg-vaccine","display_name":"BCG vaccine","score":0.9729999899864197},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.6819999814033508},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.6499999761581421},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.6940000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7431936860084534},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.678447425365448},{"id":"https://openalex.org/C176080213","wikidata":"https://www.wikidata.org/wiki/Q188010","display_name":"ABO blood group system","level":2,"score":0.647495687007904},{"id":"https://openalex.org/C2778065480","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Transitional cell carcinoma","level":4,"score":0.6286923885345459},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.5825109481811523},{"id":"https://openalex.org/C21957315","wikidata":"https://www.wikidata.org/wiki/Q287896","display_name":"Beta-2 microglobulin","level":2,"score":0.5340757369995117},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5063425302505493},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4959815442562103},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4501476585865021},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41690701246261597},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33109819889068604},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27303269505500793},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.2088940143585205},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.16987282037734985},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000017","descriptor_name":"ABO Blood-Group System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001500","descriptor_name":"BCG Vaccine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001613","descriptor_name":"beta 2-Microglobulin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001743","descriptor_name":"Urinary Bladder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001743","descriptor_name":"Urinary Bladder","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007124","descriptor_name":"Immunoenzyme Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007519","descriptor_name":"Isoantigens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","doi":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819910615%2967%3A12%3C3024%3A%3AAID-CNCR2820671216%3E3.0.CO%3B2-Q","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:1710534","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1710534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","doi":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","is_oa":true,"landing_page_url":"https://doi.org/10.1002/1097-0142(19910615)67:12<3024::aid-cncr2820671216>3.0.co;2-q","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819910615%2967%3A12%3C3024%3A%3AAID-CNCR2820671216%3E3.0.CO%3B2-Q","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2003273154.pdf","grobid_xml":"https://content.openalex.org/works/W2003273154.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1966405491","https://openalex.org/W1988899443","https://openalex.org/W1998438825","https://openalex.org/W2015535991","https://openalex.org/W2019340382","https://openalex.org/W2022797612","https://openalex.org/W2058331779","https://openalex.org/W2068015053","https://openalex.org/W2082766431","https://openalex.org/W2097065895","https://openalex.org/W2098035910","https://openalex.org/W2314674534","https://openalex.org/W2329268594","https://openalex.org/W2396780070","https://openalex.org/W2398637237","https://openalex.org/W2401894708","https://openalex.org/W2409228465","https://openalex.org/W2409885055","https://openalex.org/W2411085454","https://openalex.org/W2411811039","https://openalex.org/W2411940019","https://openalex.org/W2414572565","https://openalex.org/W2416441643","https://openalex.org/W2418118083","https://openalex.org/W2419241445","https://openalex.org/W2474371931","https://openalex.org/W3132426763","https://openalex.org/W4243650202"],"related_works":["https://openalex.org/W2398709700","https://openalex.org/W2420857521","https://openalex.org/W2157707418","https://openalex.org/W2301354725","https://openalex.org/W2111757986","https://openalex.org/W4313784203","https://openalex.org/W2079762622","https://openalex.org/W2766194852","https://openalex.org/W1876405247"],"abstract_inverted_index":{"The":[0],"response":[1,119],"of":[2,9,30,35,37,48,86,92,110,116,133,138,144],"patients":[3,19],"with":[4,66,104],"superficial":[5],"transitional":[6],"cell":[7,50],"carcinoma":[8],"the":[10,38,46,78,81,90,134],"bladder":[11,87],"(STCB)":[12],"to":[13,120],"intravesical":[14,122],"chemotherapy":[15],"is":[16,114,137],"variable;":[17],"some":[18],"enjoy":[20],"a":[21,117],"long":[22],"period":[23],"without":[24],"recurrence,":[25],"whereas":[26],"others":[27,42],"have":[28,43],"recurrence":[29],"tumor":[31],"within":[32],"2":[33],"years":[34],"removal":[36],"primary":[39],"lesion.":[40],"Previously,":[41],"demonstrated":[44],"that":[45,108,131],"loss":[47],"normal":[49],"surface":[51],"antigens,":[52],"such":[53],"as":[54],"ABO(H)":[55,93],"blood":[56],"group":[57],"antigens":[58,94],"or":[59],"beta-2":[60],"microglobulin":[61],"(B2M)":[62],"has":[63],"been":[64],"correlated":[65],"more":[67],"aggressive":[68],"behavior":[69],"by":[70],"tumor.":[71],"In":[72],"this":[73,99],"study,":[74],"using":[75],"immunohistochemical":[76],"techniques,":[77],"authors":[79],"evaluated":[80],"initial":[82],"pretreatment":[83],"biopsy":[84],"specimen":[85],"tumors":[88],"for":[89],"presence":[91],"and":[95,130],"B2M.":[96],"Data":[97],"from":[98],"sample":[100],"patient":[101],"population,":[102],"all":[103],"biopsy-proven":[105],"STCB,":[106],"indicate":[107],"expression":[109,132,143],"these":[111],"two":[112,135],"markers":[113,136],"predictive":[115,140],"therapeutic":[118],"prophylactic":[121],"bacillus":[123],"Calmette-Guerin":[124],"(BCG)":[125],"(Tice":[126],"strain)":[127],"after":[128],"resection,":[129],"greater":[139],"value":[141],"than":[142],"either":[145],"antigen":[146],"alone.":[147]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}