{"id":"https://openalex.org/W2003258557","doi":"https://doi.org/10.1016/0014-5793(96)00767-3","title":"Mitochondrial ATP synthase F1\u2010\u03b2\u2010subunit is a calcium\u2010binding protein","display_name":"Mitochondrial ATP synthase F1\u2010\u03b2\u2010subunit is a calcium\u2010binding protein","publication_year":1996,"publication_date":"1996-08-12","ids":{"openalex":"https://openalex.org/W2003258557","doi":"https://doi.org/10.1016/0014-5793(96)00767-3","mag":"2003258557","pmid":"https://pubmed.ncbi.nlm.nih.gov/8764999"},"language":"en","primary_location":{"id":"doi:10.1016/0014-5793(96)00767-3","doi":"https://doi.org/10.1016/0014-5793(96)00767-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-5793(96)00767-3","pdf_url":null,"source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111796449","display_name":"Michael J. Hubbard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"Michael J. Hubbard","raw_affiliation_strings":["Department of Biochemistry, University of Otago, Dunedin, New Zealand. mother@otago.ac.nz","Department of Biochemistry, University of Otago, P.O. Box\u00a056, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Otago, Dunedin, New Zealand. mother@otago.ac.nz","institution_ids":["https://openalex.org/I80281795"]},{"raw_affiliation_string":"Department of Biochemistry, University of Otago, P.O. Box\u00a056, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045443255","display_name":"Nicola J. McHugh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80281795","display_name":"University of Otago","ror":"https://ror.org/01jmxt844","country_code":"NZ","type":"education","lineage":["https://openalex.org/I80281795"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Nicola J. McHugh","raw_affiliation_strings":["Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin, New Zealand","institution_ids":["https://openalex.org/I80281795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111796449"],"corresponding_institution_ids":["https://openalex.org/I80281795"],"apc_list":{"value":3980,"currency":"USD","value_usd":3980},"apc_paid":null,"fwci":1.1607,"has_fulltext":false,"cited_by_count":120,"citation_normalized_percentile":{"value":0.76430925,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"391","issue":"3","first_page":"323","last_page":"329"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-atp-synthase","display_name":"mitochondrial ATP synthase","score":0.9760000109672546},{"id":"https://openalex.org/keywords/calcium-binding-proteins","display_name":"calcium-binding proteins","score":0.9169999957084656},{"id":"https://openalex.org/keywords/liver-mitochondria","display_name":"liver mitochondria","score":0.8100000023841858},{"id":"https://openalex.org/keywords/atp-production","display_name":"ATP production","score":0.5659999847412109},{"id":"https://openalex.org/keywords/calcium-pump","display_name":"calcium pump","score":0.7200000286102295},{"id":"https://openalex.org/keywords/atp-synthase-regulation","display_name":"ATP synthase regulation","score":0.6589999794960022}],"concepts":[{"id":"https://openalex.org/C119120687","wikidata":"https://www.wikidata.org/wiki/Q4654890","display_name":"ATP synthase gamma subunit","level":5,"score":0.7941446304321289},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.7756622433662415},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.7535713315010071},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5665516257286072},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.546321451663971},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.5391841530799866},{"id":"https://openalex.org/C161473406","wikidata":"https://www.wikidata.org/wiki/Q24719569","display_name":"Gi alpha subunit","level":4,"score":0.46527478098869324},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4176808297634125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41539737582206726},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3405835032463074},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.15336531400680542},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.1310628354549408},{"id":"https://openalex.org/C141315368","wikidata":"https://www.wikidata.org/wiki/Q4654881","display_name":"ATP hydrolysis","level":4,"score":0.0823121964931488},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.052377015352249146},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002135","descriptor_name":"Calcium-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002135","descriptor_name":"Calcium-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004658","descriptor_name":"Enamel Organ","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D006180","descriptor_name":"Proton-Translocating ATPases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006180","descriptor_name":"Proton-Translocating ATPases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008930","descriptor_name":"Mitochondria, Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0014-5793(96)00767-3","doi":"https://doi.org/10.1016/0014-5793(96)00767-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0014-5793(96)00767-3","pdf_url":null,"source":{"id":"https://openalex.org/S104830714","display_name":"FEBS Letters","issn_l":"0014-5793","issn":["0014-5793","1873-3468"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS Letters","raw_type":"journal-article"},{"id":"pmid:8764999","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8764999","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"FEBS letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W190061407","https://openalex.org/W575805996","https://openalex.org/W1483583252","https://openalex.org/W1491460216","https://openalex.org/W1536942450","https://openalex.org/W1570515175","https://openalex.org/W1605843386","https://openalex.org/W1653713408","https://openalex.org/W1844259691","https://openalex.org/W1919835673","https://openalex.org/W1975551314","https://openalex.org/W1981522273","https://openalex.org/W1986371653","https://openalex.org/W1989258165","https://openalex.org/W1990765567","https://openalex.org/W1996346962","https://openalex.org/W1996885362","https://openalex.org/W2002713118","https://openalex.org/W2008099154","https://openalex.org/W2017776680","https://openalex.org/W2020572156","https://openalex.org/W2042846004","https://openalex.org/W2046016490","https://openalex.org/W2046452071","https://openalex.org/W2048942378","https://openalex.org/W2058776745","https://openalex.org/W2060479536","https://openalex.org/W2063561324","https://openalex.org/W2065935004","https://openalex.org/W2071010819","https://openalex.org/W2071950147","https://openalex.org/W2075445100","https://openalex.org/W2078400965","https://openalex.org/W2087538072","https://openalex.org/W2123259277","https://openalex.org/W2124813198","https://openalex.org/W2176061808","https://openalex.org/W2255476717","https://openalex.org/W2326791154","https://openalex.org/W4235927881"],"related_works":["https://openalex.org/W2046225321","https://openalex.org/W1504530468","https://openalex.org/W2293413114","https://openalex.org/W2017888883","https://openalex.org/W7223150690","https://openalex.org/W1982113491","https://openalex.org/W1494831128","https://openalex.org/W1539851897","https://openalex.org/W2041421561","https://openalex.org/W1976832661"],"abstract_inverted_index":{"Mitochondrial":[0],"ATP":[1,33,90,95],"synthase":[2,34],"is":[3],"responsive":[4],"to":[5],"changes":[6],"in":[7,26],"cytosolic":[8],"calcium":[9,74,82,101],"concentration,":[10],"but":[11,64],"the":[12,31,58,67,71,78],"regulatory":[13],"mechanisms":[14],"are":[15],"unclear.":[16],"Here":[17],"we":[18],"identified":[19],"a":[20,40],"major":[21],"52":[22],"kDa":[23],"calcium-binding":[24,46],"protein":[25,47],"rat":[27,61],"enamel":[28],"cells":[29],"as":[30,39],"mitochondrial":[32],"F1-beta-subunit.":[35],"The":[36],"F1-beta-subunit":[37,59,80],"behaved":[38],"low":[41],"affinity":[42],"and":[43,92],"moderate":[44],"capacity":[45],"during":[48],"comparative":[49],"45Ca":[50],"overlay":[51],"analyses.":[52],"Equivalent":[53],"behavior":[54],"was":[55],"shown":[56],"by":[57,66],"from":[60],"liver":[62],"mitochondria,":[63],"not":[65],"homologous":[68],"F1-alpha-subunit,":[69],"supporting":[70],"specificity":[72],"of":[73],"binding.":[75],"Evidence":[76],"that":[77],"catalytic":[79],"binds":[81],"specifically":[83],"introduces":[84],"new":[85],"mechanistic":[86],"possibilities":[87],"for":[88,99],"regulating":[89],"synthase,":[91],"thereby":[93],"coordinating":[94],"production":[96],"with":[97],"demand":[98],"ATP-fuelled":[100],"pump":[102],"activity.":[103]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}