{"id":"https://openalex.org/W2003247693","doi":"https://doi.org/10.1039/c2an35483g","title":"Fourier transform infrared imaging analysis in discrimination studies of squamous cell carcinoma","display_name":"Fourier transform infrared imaging analysis in discrimination studies of squamous cell carcinoma","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2003247693","doi":"https://doi.org/10.1039/c2an35483g","mag":"2003247693","pmid":"https://pubmed.ncbi.nlm.nih.gov/22792538"},"language":"en","primary_location":{"id":"doi:10.1039/c2an35483g","doi":"https://doi.org/10.1039/c2an35483g","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c2an35483g","pdf_url":null,"source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061050992","display_name":"Johannes Dominikus Pallua","orcid":"https://orcid.org/0000-0003-0203-213X","observed_orcids":["https://orcid.org/0000-0003-0203-213X"]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"J. D. Pallua","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111604006","display_name":"Christine Pezzei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"C. Pezzei","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109048686","display_name":"B. Zelger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"B. Zelger","raw_affiliation_strings":["Department of Pathology, Innsbruck Medical University, Muellerstra\u00dfe 44, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Innsbruck Medical University, Muellerstra\u00dfe 44, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038967220","display_name":"Georg Schaefer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"G. Schaefer","raw_affiliation_strings":["Department of Urology, Innsbruck Medical University, Anichstra\u00dfe 35, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Innsbruck Medical University, Anichstra\u00dfe 35, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074195237","display_name":"L. K. Bittner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"L. K. Bittner","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043779308","display_name":"V. A. Huck-Pezzei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"V. A. Huck-Pezzei","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060050900","display_name":"S.A. Sch\u00f6nbichler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"S. A. Schoenbichler","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025933410","display_name":"Hans Hahn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"H. Hahn","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049216375","display_name":"A. Kloss-Brandstaetter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"A. Kloss-Brandstaetter","raw_affiliation_strings":["Division of Genetic Epidemiology, Innsbruck Medical University, Schoepfstra\u00dfe 41, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Genetic Epidemiology, Innsbruck Medical University, Schoepfstra\u00dfe 41, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009327709","display_name":"Frank Rudolf Kloss","orcid":"https://orcid.org/0000-0001-6748-6365","observed_orcids":["https://orcid.org/0000-0001-6748-6365"]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"F. Kloss","raw_affiliation_strings":["Department for Cranio-Maxillofacial and Oral Surgery, Innsbruck Medical University, Anichstra\u00dfe 35, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department for Cranio-Maxillofacial and Oral Surgery, Innsbruck Medical University, Anichstra\u00dfe 35, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110029148","display_name":"Guenther Karl Bonn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"G. K. Bonn","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035278611","display_name":"Christian Wolfgang Huck","orcid":"https://orcid.org/0000-0002-6272-3242","observed_orcids":["https://orcid.org/0000-0002-6272-3242"]},"institutions":[{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"C. W. Huck","raw_affiliation_strings":["Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analytical Chemistry and Radiochemistry, CCB-Center for Chemistry and Biomedicine, Leopold-Franzens University, Innrain 80-82-52a, 6020 Innsbruck, Austria","institution_ids":["https://openalex.org/I190249584"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5035278611"],"corresponding_institution_ids":["https://openalex.org/I190249584"],"apc_list":null,"apc_paid":null,"fwci":2.0755,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.89429952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"137","issue":"17","first_page":"3965","last_page":"3965"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12994","display_name":"Infrared Thermography in Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":0.9549999833106995},{"id":"https://openalex.org/keywords/fourier-transform-infrared-imaging","display_name":"Fourier transform infrared imaging","score":0.8849999904632568},{"id":"https://openalex.org/keywords/molecular-imaging","display_name":"molecular imaging","score":0.7009999752044678},{"id":"https://openalex.org/keywords/multivariate-image-analysis","display_name":"multivariate image analysis","score":0.8130000233650208},{"id":"https://openalex.org/keywords/formalin-fixed-paraffin-embedded-tissue","display_name":"formalin-fixed paraffin-embedded tissue","score":0.9750000238418579},{"id":"https://openalex.org/keywords/tissue-microarray","display_name":"tissue microarray","score":0.968999981880188},{"id":"https://openalex.org/keywords/cancer-discrimination","display_name":"cancer discrimination","score":0.4659999907016754},{"id":"https://openalex.org/keywords/chemometrics","display_name":"chemometrics","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.6815369725227356},{"id":"https://openalex.org/C102519508","wikidata":"https://www.wikidata.org/wiki/Q6520159","display_name":"Fourier transform","level":2,"score":0.6146603226661682},{"id":"https://openalex.org/C65597285","wikidata":"https://www.wikidata.org/wiki/Q5090469","display_name":"Chemical imaging","level":3,"score":0.4923797845840454},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.48961693048477173},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.41864585876464844},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.41676419973373413},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40529265999794006},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.37785428762435913},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.23604938387870789},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.20346137881278992},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14546650648117065},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11960047483444214},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11925888061523438},{"id":"https://openalex.org/C159078339","wikidata":"https://www.wikidata.org/wiki/Q959005","display_name":"Hyperspectral imaging","level":2,"score":0.11337646842002869},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08045798540115356},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D025341","descriptor_name":"Principal Component Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1039/c2an35483g","doi":"https://doi.org/10.1039/c2an35483g","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c2an35483g","pdf_url":null,"source":{"id":"https://openalex.org/S105746325","display_name":"The Analyst","issn_l":"0003-2654","issn":["0003-2654","1364-5528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"journal-article"},{"id":"pmid:22792538","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22792538","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Analyst","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327491","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W593007606","https://openalex.org/W1540345282","https://openalex.org/W1555036541","https://openalex.org/W1874474895","https://openalex.org/W1969190266","https://openalex.org/W1971637521","https://openalex.org/W1972956380","https://openalex.org/W1975241121","https://openalex.org/W1975374743","https://openalex.org/W1982210717","https://openalex.org/W1984167228","https://openalex.org/W1984993288","https://openalex.org/W1987389391","https://openalex.org/W1987955706","https://openalex.org/W1991745307","https://openalex.org/W1995650527","https://openalex.org/W1997433520","https://openalex.org/W2004128332","https://openalex.org/W2007668113","https://openalex.org/W2009694558","https://openalex.org/W2012994392","https://openalex.org/W2013800800","https://openalex.org/W2015151924","https://openalex.org/W2016081624","https://openalex.org/W2019638166","https://openalex.org/W2020830322","https://openalex.org/W2024971501","https://openalex.org/W2033640080","https://openalex.org/W2040540468","https://openalex.org/W2044214699","https://openalex.org/W2045573336","https://openalex.org/W2057814995","https://openalex.org/W2060719207","https://openalex.org/W2067207141","https://openalex.org/W2070586147","https://openalex.org/W2100299516","https://openalex.org/W2116050737","https://openalex.org/W2135399477","https://openalex.org/W2135908472","https://openalex.org/W2139790640","https://openalex.org/W2159294687","https://openalex.org/W2163171830","https://openalex.org/W2167084755","https://openalex.org/W2171334157","https://openalex.org/W2417191605","https://openalex.org/W2461255982"],"related_works":["https://openalex.org/W7214543904","https://openalex.org/W7216847203","https://openalex.org/W7147345442","https://openalex.org/W3180853865","https://openalex.org/W4415743893","https://openalex.org/W6887883217","https://openalex.org/W1977642291","https://openalex.org/W2074800686","https://openalex.org/W2793635941","https://openalex.org/W3163971454"],"abstract_inverted_index":{"Oral":[0],"squamous":[1,327,340],"cell":[2,328,341],"carcinoma":[3,342],"(OSCC)":[4],"of":[5,15,25,69,73,84,97,108,120,126,136,158,162,180,189,199,268,279,291,313,322,339],"the":[6,20,65,70,81,106,124,133,137,159,187,200,210,223,236,283,292,304,319,323],"oral":[7,21],"cavity":[8],"and":[9,31,36,67,102,139,144,170,178,186,228,242,248,336],"oropharynx":[10],"represents":[11],"more":[12],"than":[13],"95%":[14],"all":[16],"malignant":[17],"neoplasms":[18],"in":[19,114,194,303],"cavity.":[22],"Histomorphological":[23],"evaluation":[24,245],"this":[26,121,148,206],"cancer":[27],"type":[28],"is":[29,89,103,123,152,192,254],"invasive":[30],"remains":[32],"a":[33,90,98],"time":[34],"consuming":[35],"subjective":[37],"technique.":[38],"Therefore,":[39,203],"novel":[40,211],"approaches":[41],"for":[42,64,80,205,214,311],"histological":[43,289],"recognition":[44],"are":[45,184,219],"necessary":[46],"to":[47,154,196,234,256,282],"identify":[48],"malignancy":[49],"at":[50],"an":[51,61,273],"early":[52],"stage.":[53],"Fourier":[54],"transform":[55],"infrared":[56],"(FTIR)":[57],"imaging":[58,88,96,149,182,227,281,315],"has":[59],"become":[60],"essential":[62],"tool":[63],"detection":[66],"characterization":[68],"molecular":[71,95,128],"components":[72],"biological":[74,100],"processes,":[75],"such":[76],"as":[77],"those":[78],"responsible":[79],"dynamic":[82],"properties":[83],"tumor":[85],"progression.":[86],"FTIR":[87,181,226,280,314,348],"modern":[91],"analytical":[92,275],"technique":[93,122],"enabling":[94],"complex":[99],"sample":[101],"based":[104,208],"on":[105,209],"absorption":[107],"IR":[109,259,324],"radiation":[110],"by":[111,288,347],"vibrational":[112],"transitions":[113],"covalent":[115],"bonds.":[116],"One":[117],"major":[118],"advantage":[119,198],"acquisition":[125],"local":[127],"expression":[129],"profiles,":[130],"while":[131],"maintaining":[132],"topographic":[134],"integrity":[135],"tissue":[138,237,265,270,285,298,329,343],"avoiding":[140],"time-consuming":[141],"extraction,":[142],"purification,":[143],"separation":[145],"steps.":[146],"With":[147],"technique,":[150],"it":[151,253],"possible":[153,255],"obtain":[155],"unique":[156],"images":[157,325],"spatial":[160,175],"distribution":[161],"proteins,":[163],"lipids,":[164],"carbohydrates,":[165],"cholesterols,":[166],"nucleic":[167],"acids,":[168],"phospholipids,":[169],"small":[171],"molecules":[172],"with":[173],"high":[174],"resolution.":[176],"Analysis":[177],"visualization":[179],"datasets":[183],"challenging":[185],"use":[188],"chemometric":[190],"tools":[191],"crucial":[193],"order":[195],"take":[197],"full":[201],"measurement.":[202],"methodologies":[204],"task":[207],"developed":[212],"algorithm":[213],"multivariate":[215],"image":[216],"analysis":[217,230,247],"(MIA)":[218],"often":[220],"necessary.":[221],"In":[222],"present":[224],"study,":[225],"data":[229,244,316],"methods":[231],"were":[232],"combined":[233],"optimize":[235],"measurement":[238],"mode":[239],"after":[240],"deparaffinization":[241],"subsequent":[243],"(univariate":[246],"MIAs).":[249],"We":[250],"demonstrate":[251],"that":[252,295,334],"collect":[257],"excellent":[258],"spectra":[260],"from":[261,326],"formalin-fixed":[262],"paraffin-embedded":[263],"(FFPE)":[264],"microarrays":[266],"(TMAs)":[267],"OSCC":[269],"sections":[271,293],"employing":[272],"optimised":[274],"protocol.":[276],"The":[277,307],"correlation":[278],"morphological":[284],"features":[286],"obtained":[287],"staining":[290],"demonstrated":[294],"many":[296],"histomorphological":[297],"patterns":[299],"can":[300,344],"be":[301,345],"visualized":[302],"colour":[305],"images.":[306],"different":[308],"algorithms":[309],"used":[310],"MIAs":[312],"dramatically":[317],"increased":[318],"information":[320],"content":[321],"sections.":[330],"These":[331],"findings":[332],"indicate":[333],"intra-operative":[335],"surgical":[337],"specimens":[338],"characterized":[346],"imaging.":[349]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}